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The map label for this gene is mtnN [H]

Identifier: 116689465

GI number: 116689465

Start: 1596017

End: 1596811

Strand: Direct

Name: mtnN [H]

Synonym: Bcen2424_1443

Alternate gene names: 116689465

Gene position: 1596017-1596811 (Clockwise)

Preceding gene: 116689464

Following gene: 116689467

Centisome position: 45.81

GC content: 71.19

Gene sequence:

>795_bases
ATGGACGTCGACCTCGCCGTGACGCCTGCCGCGCGCCCGCTCGGCATTCTGGCCGCGCTGCCCGAGGAGCTCGGCGACCT
GATCGCCGCGATGCGCGCCGACGGCGCGATGAAGACGGTCACGCTCGGCCGCCGCGATTACCACGTCGGCACCGTGCACG
GCGCGGCCTGCGTCGTCACGCTCGCGCGGATCGGCAAGGTCGCGGCCGCCGCGACGGTCAGCGCGCTGATCCACGTGTTC
GGCGTGTCGGGCGTGGTGTTCACCGGCGTCGCGGGCGGTGTGTCGCGCACGGTTCGGGTCGGCGACGTCGTCGTGGCCGA
TACGCTGCTGCAGCACGATCTCGACGCGTCGCCGCTCTTTCCGCGCTACGAGGTGCCCTTGCTCGGCATCACGCGTTTCG
CGACCGACGCGGCGCTGACGGCCCGCTTGCGGGCTGCATGCACGCTGTTCGTCGAGGAGGAGGGCGCGCGGTTCGCCGAG
CGCTTCGGGCTCGCCGGCGCGGCGCTGCACGCGGGGCTCGTCATCAGCGGCGACCGTTTCGTGTCGAGCGAGCAGGAGGT
CGTTGCGCTGCGCGACGCGCTGCCGGACGCACTCGCGGTCGAGATGGAAGGCGCGGCGATCGCGCAGGTGTGCGCGGAAC
ACGACGTGCCGTTCGCGCTCGTGCGCACGATCTCCGATACGGCCGACGATCACGCGACGCAGTCGTTCTCGCATTTCCTG
TCGGCGATCGCGAGCAGCTATTCGTCCGGCATCCTCAAGCGTTTTCTGACGCTGCATGCGACGACGGCGGCCTGA

Upstream 100 bases:

>100_bases
TCGAAGGCAACGGCACCGACGCGAAGGCGCAGGTGAAGTTCAAGCGCCACGGCGAGAAATGGCTCGCGCTCGCGGTCGCG
AAACTGCAGGCGGTGGAATG

Downstream 100 bases:

>100_bases
AGCCGCCGTCTCGTACTTTTCCCATCAAACCGCTCGACTGGCCGCGGCGCGCACGCCGCGGCCAGTCGTTCGTCACGCCT
TTTTGCGCCGGCTGCTTTCG

Product: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase

Products: NA

Alternate protein names: MTA/SAH nucleosidase; MTAN; 5'-methylthioadenosine nucleosidase; MTA nucleosidase; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase [H]

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MDVDLAVTPAARPLGILAALPEELGDLIAAMRADGAMKTVTLGRRDYHVGTVHGAACVVTLARIGKVAAAATVSALIHVF
GVSGVVFTGVAGGVSRTVRVGDVVVADTLLQHDLDASPLFPRYEVPLLGITRFATDAALTARLRAACTLFVEEEGARFAE
RFGLAGAALHAGLVISGDRFVSSEQEVVALRDALPDALAVEMEGAAIAQVCAEHDVPFALVRTISDTADDHATQSFSHFL
SAIASSYSSGILKRFLTLHATTAA

Sequences:

>Translated_264_residues
MDVDLAVTPAARPLGILAALPEELGDLIAAMRADGAMKTVTLGRRDYHVGTVHGAACVVTLARIGKVAAAATVSALIHVF
GVSGVVFTGVAGGVSRTVRVGDVVVADTLLQHDLDASPLFPRYEVPLLGITRFATDAALTARLRAACTLFVEEEGARFAE
RFGLAGAALHAGLVISGDRFVSSEQEVVALRDALPDALAVEMEGAAIAQVCAEHDVPFALVRTISDTADDHATQSFSHFL
SAIASSYSSGILKRFLTLHATTAA
>Mature_264_residues
MDVDLAVTPAARPLGILAALPEELGDLIAAMRADGAMKTVTLGRRDYHVGTVHGAACVVTLARIGKVAAAATVSALIHVF
GVSGVVFTGVAGGVSRTVRVGDVVVADTLLQHDLDASPLFPRYEVPLLGITRFATDAALTARLRAACTLFVEEEGARFAE
RFGLAGAALHAGLVISGDRFVSSEQEVVALRDALPDALAVEMEGAAIAQVCAEHDVPFALVRTISDTADDHATQSFSHFL
SAIASSYSSGILKRFLTLHATTAA

Specific function: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786354, Length=238, Percent_Identity=32.7731092436975, Blast_Score=98, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 27402; Mature: 27402

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVDLAVTPAARPLGILAALPEELGDLIAAMRADGAMKTVTLGRRDYHVGTVHGAACVVT
CCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEHHHHHHHHH
LARIGKVAAAATVSALIHVFGVSGVVFTGVAGGVSRTVRVGDVVVADTLLQHDLDASPLF
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHCEEEHHHHHHHHHHHHHCCCCCCCC
PRYEVPLLGITRFATDAALTARLRAACTLFVEEEGARFAERFGLAGAALHAGLVISGDRF
CCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHCCCHHHHHCCEEEECCHH
VSSEQEVVALRDALPDALAVEMEGAAIAQVCAEHDVPFALVRTISDTADDHATQSFSHFL
CCCCHHHHHHHHCCCCHHEEEECCHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHH
SAIASSYSSGILKRFLTLHATTAA
HHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDVDLAVTPAARPLGILAALPEELGDLIAAMRADGAMKTVTLGRRDYHVGTVHGAACVVT
CCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEHHHHHHHHH
LARIGKVAAAATVSALIHVFGVSGVVFTGVAGGVSRTVRVGDVVVADTLLQHDLDASPLF
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHCEEEHHHHHHHHHHHHHCCCCCCCC
PRYEVPLLGITRFATDAALTARLRAACTLFVEEEGARFAERFGLAGAALHAGLVISGDRF
CCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHCCCHHHHHCCEEEECCHH
VSSEQEVVALRDALPDALAVEMEGAAIAQVCAEHDVPFALVRTISDTADDHATQSFSHFL
CCCCHHHHHHHHCCCCHHEEEECCHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHH
SAIASSYSSGILKRFLTLHATTAA
HHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA