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The map label for this gene is yycG [H]

Identifier: 116689460

GI number: 116689460

Start: 1586487

End: 1588874

Strand: Direct

Name: yycG [H]

Synonym: Bcen2424_1438

Alternate gene names: 116689460

Gene position: 1586487-1588874 (Clockwise)

Preceding gene: 116689459

Following gene: 116689461

Centisome position: 45.54

GC content: 69.56

Gene sequence:

>2388_bases
ATGAAACCCGACTCCGTTTCTCCGCGGCGGCACCTCGGCCGCCGCTTCCTGATCGAATGGATCGCGATCGGCTGCCTCGG
GATCGCGGTGATTCTCGTGTGCGCGCTCGGCCGCCTGTCGTCGAGTGTCGACGGGCTGATCTACGACCGGCTGCTGATGC
TGCGCAGCCTGCCGCTGTCGCCCGACGTGGTCGTCGTCGACATCGACAACCAGAGCGTATCCGCGCTCGGCCGCTGGCCG
TGGCCGCGCGACGTGCATGCGCGGCTGCTCGATACGCTGGCGCGCGCGCAGCCGGCCGCGGTCGTCTACGACGTGCTGTT
TACCGAACCGTCGCCGGAGGATCGCGCGTTCGCGGACGCGATGAGTCGCGTGCCGACCTTCCTGCCCGTGCTGTTGAGCC
CCGAGCAGGCGGACGGCACGCGCTCCGTCGATCCGCCGGTCGCCGCGCTCGCCGCGCGCGCGACGGGGCTGGGCCATATC
AATCTCGAAGTCGATCGCGACGGCATCGTGCGCAGCGTCGCGCTGTTCGAAAGCGACGGCCGCGTGCGCTGGCCGCAACT
GATGGTGCCCGTCTATCGCGCGATCCAGGCCGGCCGGCTGCACCCGGTCGGCGGCATGCCCGGCGCGGACGCGCACGACC
TGTCGCGTGATGCGGCGGGCGATGGCCGCTACCTGATTCCGTTCAGCCGCAATACGCCCGCGTATCCGACGCTGTCGTTC
GACGACGTGCTCGAAGGGCGCGTGAAGCCCGACGCGCTGCGCGGCAAGATCGTCGTCGTCGGCGTGACGGCGTCCGGGCT
GTACGATCGCTTCGCGACGCCGGTGTCCGGCGAGTTCGGCCCGCTCGCCGGCGTGTATATCCATGCCAACGTGCTCGACA
TGCTGGCGACCGGCAGTGCGATCTCGCCCGCGTCGCGTGCGGGGTTGTTCGTCGCGTCGCTGCTGCCGCTCGCCGTGTTG
CTGGGCGGCTTCCTGATGCTGTCGCCGTGGCGTGCGTTGCTGCTGACGCTGAGCCTGGCCGCGCTCGCCGTCGTCGCGAG
CCTGGCGCTGCTGTTCGAGGCGCGCATCTGGCTGACGCCGGCGCCCGCGATCTTCGGGCTGATCGCCGTCTATCCGATCT
GGAACTGGCGGCGGCTGGAAATGACGATGTCGTACCTGCGCCGCGAGCTGCAGAAGCTCGCCGACGAGCCGCACCTGCTG
CCGGAGGCGCCGCGCACGCGCAGCGTCGGCGGCGACGTGCTGGAGCGGCAGATGGCGCTGATGGCGCAGGCCGCGCAGCG
TGTGCAGGACATGAAGCGCTTCGTGTGGGACAGCCTCGACAGCATGCCCGAGCCGATCTTCGTGACCGACCTCGCCGGCA
CCGTGCTGATCGCCAACCATGCGGCGAAACGCTACGGGTCGCGGCTCGCGCTGCCGCTGCCGGAAGGGCGGCCGCTGCGC
ACCGCGCTCGGCGAGCTGACCTTCATGAAGACCGTCGACGGCAACGCCGAGCATGACGCGGCGATCCGCGAGCACTGGCC
GGCCGTGCTCGATCCGACGCTCGAGGCCGAGCACGACGCGATGGCGCGCGGCATCGAGGTGCGCGATCGCGACGGGCTCG
ACCATCTGCTACGCTACGCGGCATGTACGAACGCGCAAGGGCGCGTGACCGGCTGGATTGCCGGCCTCGTCGACGTGACC
GAGCTGCACGCGGCCGAGCGGCAGCGCGAGGAAGCGCTGCACCTGCTGTCGCACGACATGCGTTCGCCGCAGTCGTCGAT
CCTCGCGCTGGTCGAGATCGAGCGCGATCGCGTCGAAAGCGACGCGATGCGCGGGCTGCTCGCGCGAATCGAGCGCTATG
CGCACCGCGCGCTGTCGCTCGCCGACGAGTTCGTGCAACTGGCGCGCGCCGAGTCGCAGGCGTACCAGCTCGAGGTGACG
AGCCTCGTCGACGTGCTGATCGACGCGAGCGACGAGGTGTGGCCGCAGGCGCAGGCGAAGCACATTCGCGTGGAGACCGG
CGTGGGCACCGACATGTGCTGGGTGCGCGCGGACCGCTCGCTGATCACGCGCGCCTTCGTGAACCTGCTGAACAATGCGG
TCAAATACAGTCCGTCCGACACGGTGATCACGTGTACGCTGACGGTCGAGCACGCATCGAAGCGGATGTTCTGTACGATT
CGCGATCAGGGGTACGGCATTGCGCCGGAAGATCAGCGGCATCTGTTCGAGCGTTTCAAGCGATTCCATGCCGGCGAGCG
GCCCGAAATCTCGGGTTCCGGGCTCGGCATGGCGTTCGTGAAGACGGTCGTCACGCGCCATGGGGGCAGCGTGTCGGTCG
ACAGCGAAGTGGGTGTCGGCACCGCGGTGACGGTGTCGCTGCCCGCGATCGACGAGCCGTCCGCCTGA

Upstream 100 bases:

>100_bases
TATTTCTGGGCCGTGACCGTCGAGGAATTCGAAGGCGGCAAGTTCTACGAGAAGACCAGTCCGGTCAGCGCGTTCACGTT
GTCGCGCTGATCCGCGGCGC

Downstream 100 bases:

>100_bases
CAGGGCCGGGCGCGACGGCAGGCATTTGGGGAAAGTCATGAGAAAGCAATGGGCAGCGACCGCGCTGGCGGCGTCGCTGT
TGACGGGTTGCGCCGGCGTG

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 795; Mature: 795

Protein sequence:

>795_residues
MKPDSVSPRRHLGRRFLIEWIAIGCLGIAVILVCALGRLSSSVDGLIYDRLLMLRSLPLSPDVVVVDIDNQSVSALGRWP
WPRDVHARLLDTLARAQPAAVVYDVLFTEPSPEDRAFADAMSRVPTFLPVLLSPEQADGTRSVDPPVAALAARATGLGHI
NLEVDRDGIVRSVALFESDGRVRWPQLMVPVYRAIQAGRLHPVGGMPGADAHDLSRDAAGDGRYLIPFSRNTPAYPTLSF
DDVLEGRVKPDALRGKIVVVGVTASGLYDRFATPVSGEFGPLAGVYIHANVLDMLATGSAISPASRAGLFVASLLPLAVL
LGGFLMLSPWRALLLTLSLAALAVVASLALLFEARIWLTPAPAIFGLIAVYPIWNWRRLEMTMSYLRRELQKLADEPHLL
PEAPRTRSVGGDVLERQMALMAQAAQRVQDMKRFVWDSLDSMPEPIFVTDLAGTVLIANHAAKRYGSRLALPLPEGRPLR
TALGELTFMKTVDGNAEHDAAIREHWPAVLDPTLEAEHDAMARGIEVRDRDGLDHLLRYAACTNAQGRVTGWIAGLVDVT
ELHAAERQREEALHLLSHDMRSPQSSILALVEIERDRVESDAMRGLLARIERYAHRALSLADEFVQLARAESQAYQLEVT
SLVDVLIDASDEVWPQAQAKHIRVETGVGTDMCWVRADRSLITRAFVNLLNNAVKYSPSDTVITCTLTVEHASKRMFCTI
RDQGYGIAPEDQRHLFERFKRFHAGERPEISGSGLGMAFVKTVVTRHGGSVSVDSEVGVGTAVTVSLPAIDEPSA

Sequences:

>Translated_795_residues
MKPDSVSPRRHLGRRFLIEWIAIGCLGIAVILVCALGRLSSSVDGLIYDRLLMLRSLPLSPDVVVVDIDNQSVSALGRWP
WPRDVHARLLDTLARAQPAAVVYDVLFTEPSPEDRAFADAMSRVPTFLPVLLSPEQADGTRSVDPPVAALAARATGLGHI
NLEVDRDGIVRSVALFESDGRVRWPQLMVPVYRAIQAGRLHPVGGMPGADAHDLSRDAAGDGRYLIPFSRNTPAYPTLSF
DDVLEGRVKPDALRGKIVVVGVTASGLYDRFATPVSGEFGPLAGVYIHANVLDMLATGSAISPASRAGLFVASLLPLAVL
LGGFLMLSPWRALLLTLSLAALAVVASLALLFEARIWLTPAPAIFGLIAVYPIWNWRRLEMTMSYLRRELQKLADEPHLL
PEAPRTRSVGGDVLERQMALMAQAAQRVQDMKRFVWDSLDSMPEPIFVTDLAGTVLIANHAAKRYGSRLALPLPEGRPLR
TALGELTFMKTVDGNAEHDAAIREHWPAVLDPTLEAEHDAMARGIEVRDRDGLDHLLRYAACTNAQGRVTGWIAGLVDVT
ELHAAERQREEALHLLSHDMRSPQSSILALVEIERDRVESDAMRGLLARIERYAHRALSLADEFVQLARAESQAYQLEVT
SLVDVLIDASDEVWPQAQAKHIRVETGVGTDMCWVRADRSLITRAFVNLLNNAVKYSPSDTVITCTLTVEHASKRMFCTI
RDQGYGIAPEDQRHLFERFKRFHAGERPEISGSGLGMAFVKTVVTRHGGSVSVDSEVGVGTAVTVSLPAIDEPSA
>Mature_795_residues
MKPDSVSPRRHLGRRFLIEWIAIGCLGIAVILVCALGRLSSSVDGLIYDRLLMLRSLPLSPDVVVVDIDNQSVSALGRWP
WPRDVHARLLDTLARAQPAAVVYDVLFTEPSPEDRAFADAMSRVPTFLPVLLSPEQADGTRSVDPPVAALAARATGLGHI
NLEVDRDGIVRSVALFESDGRVRWPQLMVPVYRAIQAGRLHPVGGMPGADAHDLSRDAAGDGRYLIPFSRNTPAYPTLSF
DDVLEGRVKPDALRGKIVVVGVTASGLYDRFATPVSGEFGPLAGVYIHANVLDMLATGSAISPASRAGLFVASLLPLAVL
LGGFLMLSPWRALLLTLSLAALAVVASLALLFEARIWLTPAPAIFGLIAVYPIWNWRRLEMTMSYLRRELQKLADEPHLL
PEAPRTRSVGGDVLERQMALMAQAAQRVQDMKRFVWDSLDSMPEPIFVTDLAGTVLIANHAAKRYGSRLALPLPEGRPLR
TALGELTFMKTVDGNAEHDAAIREHWPAVLDPTLEAEHDAMARGIEVRDRDGLDHLLRYAACTNAQGRVTGWIAGLVDVT
ELHAAERQREEALHLLSHDMRSPQSSILALVEIERDRVESDAMRGLLARIERYAHRALSLADEFVQLARAESQAYQLEVT
SLVDVLIDASDEVWPQAQAKHIRVETGVGTDMCWVRADRSLITRAFVNLLNNAVKYSPSDTVITCTLTVEHASKRMFCTI
RDQGYGIAPEDQRHLFERFKRFHAGERPEISGSGLGMAFVKTVVTRHGGSVSVDSEVGVGTAVTVSLPAIDEPSA

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG4252

COG function: function code T; Predicted transmembrane sensor domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=387, Percent_Identity=26.6149870801034, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1786783, Length=222, Percent_Identity=29.2792792792793, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1786600, Length=238, Percent_Identity=26.890756302521, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1786912, Length=237, Percent_Identity=25.3164556962025, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1788549, Length=297, Percent_Identity=24.2424242424242, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI145693157, Length=227, Percent_Identity=22.0264317180617, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1790436, Length=232, Percent_Identity=27.5862068965517, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1787894, Length=244, Percent_Identity=27.8688524590164, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1789149, Length=225, Percent_Identity=24, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1788393, Length=235, Percent_Identity=24.2553191489362, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1789808, Length=214, Percent_Identity=27.5700934579439, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790346, Length=239, Percent_Identity=25.1046025104602, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 86946; Mature: 86946

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPDSVSPRRHLGRRFLIEWIAIGCLGIAVILVCALGRLSSSVDGLIYDRLLMLRSLPLS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PDVVVVDIDNQSVSALGRWPWPRDVHARLLDTLARAQPAAVVYDVLFTEPSPEDRAFADA
CCEEEEEECCCCHHHHCCCCCCHHHHHHHHHHHHHCCCHHHEEHHHCCCCCCCHHHHHHH
MSRVPTFLPVLLSPEQADGTRSVDPPVAALAARATGLGHINLEVDRDGIVRSVALFESDG
HHHCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEEECCCCHHHHHHEEECCC
RVRWPQLMVPVYRAIQAGRLHPVGGMPGADAHDLSRDAAGDGRYLIPFSRNTPAYPTLSF
CEECHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCCCCCEEEEECCCCCCCCCCCH
DDVLEGRVKPDALRGKIVVVGVTASGLYDRFATPVSGEFGPLAGVYIHANVLDMLATGSA
HHHHCCCCCCHHHCCEEEEEEECCHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHHHCCCC
ISPASRAGLFVASLLPLAVLLGGFLMLSPWRALLLTLSLAALAVVASLALLFEARIWLTP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
APAIFGLIAVYPIWNWRRLEMTMSYLRRELQKLADEPHLLPEAPRTRSVGGDVLERQMAL
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHH
MAQAAQRVQDMKRFVWDSLDSMPEPIFVTDLAGTVLIANHAAKRYGSRLALPLPEGRPLR
HHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHEEHHHHHHHHCCEEEEECCCCCCHH
TALGELTFMKTVDGNAEHDAAIREHWPAVLDPTLEAEHDAMARGIEVRDRDGLDHLLRYA
HHHHHHHEEEECCCCCCCCHHHHHCCCHHCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHH
ACTNAQGRVTGWIAGLVDVTELHAAERQREEALHLLSHDMRSPQSSILALVEIERDRVES
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEEEHHHHHHH
DAMRGLLARIERYAHRALSLADEFVQLARAESQAYQLEVTSLVDVLIDASDEVWPQAQAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHCCCCCCCCCCCCC
HIRVETGVGTDMCWVRADRSLITRAFVNLLNNAVKYSPSDTVITCTLTVEHASKRMFCTI
EEEEECCCCCCCCEECCCHHHHHHHHHHHHHHHHEECCCCCEEEEEEEEECCCCEEEEEE
RDQGYGIAPEDQRHLFERFKRFHAGERPEISGSGLGMAFVKTVVTRHGGSVSVDSEVGVG
ECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCC
TAVTVSLPAIDEPSA
EEEEEEECCCCCCCC
>Mature Secondary Structure
MKPDSVSPRRHLGRRFLIEWIAIGCLGIAVILVCALGRLSSSVDGLIYDRLLMLRSLPLS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PDVVVVDIDNQSVSALGRWPWPRDVHARLLDTLARAQPAAVVYDVLFTEPSPEDRAFADA
CCEEEEEECCCCHHHHCCCCCCHHHHHHHHHHHHHCCCHHHEEHHHCCCCCCCHHHHHHH
MSRVPTFLPVLLSPEQADGTRSVDPPVAALAARATGLGHINLEVDRDGIVRSVALFESDG
HHHCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEEECCCCHHHHHHEEECCC
RVRWPQLMVPVYRAIQAGRLHPVGGMPGADAHDLSRDAAGDGRYLIPFSRNTPAYPTLSF
CEECHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCCCCCEEEEECCCCCCCCCCCH
DDVLEGRVKPDALRGKIVVVGVTASGLYDRFATPVSGEFGPLAGVYIHANVLDMLATGSA
HHHHCCCCCCHHHCCEEEEEEECCHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHHHCCCC
ISPASRAGLFVASLLPLAVLLGGFLMLSPWRALLLTLSLAALAVVASLALLFEARIWLTP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
APAIFGLIAVYPIWNWRRLEMTMSYLRRELQKLADEPHLLPEAPRTRSVGGDVLERQMAL
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHH
MAQAAQRVQDMKRFVWDSLDSMPEPIFVTDLAGTVLIANHAAKRYGSRLALPLPEGRPLR
HHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHEEHHHHHHHHCCEEEEECCCCCCHH
TALGELTFMKTVDGNAEHDAAIREHWPAVLDPTLEAEHDAMARGIEVRDRDGLDHLLRYA
HHHHHHHEEEECCCCCCCCHHHHHCCCHHCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHH
ACTNAQGRVTGWIAGLVDVTELHAAERQREEALHLLSHDMRSPQSSILALVEIERDRVES
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEEEHHHHHHH
DAMRGLLARIERYAHRALSLADEFVQLARAESQAYQLEVTSLVDVLIDASDEVWPQAQAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHCCCCCCCCCCCCC
HIRVETGVGTDMCWVRADRSLITRAFVNLLNNAVKYSPSDTVITCTLTVEHASKRMFCTI
EEEEECCCCCCCCEECCCHHHHHHHHHHHHHHHHEECCCCCEEEEEEEEECCCCEEEEEE
RDQGYGIAPEDQRHLFERFKRFHAGERPEISGSGLGMAFVKTVVTRHGGSVSVDSEVGVG
ECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCC
TAVTVSLPAIDEPSA
EEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]