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The map label for this gene is pkn1 [H]

Identifier: 116624323

GI number: 116624323

Start: 6575021

End: 6575701

Strand: Reverse

Name: pkn1 [H]

Synonym: Acid_5241

Alternate gene names: 116624323

Gene position: 6575701-6575021 (Counterclockwise)

Preceding gene: 116624324

Following gene: 116624322

Centisome position: 65.98

GC content: 65.93

Gene sequence:

>681_bases
ATGACACCCGACGATCTCTTGCCGGTACCCGGCGGCGAATTCCTCATGGGCCAGGCCGATGGGCGCGATGAAGAGCGCCC
GCCGCACCGTGTCGCGCTCACCCCTTTTCGCCTCTGCCGTTATCAGGTGACCAATGCGGATTACGACCACTTCCGGAAGG
CCACCCTCCGCGATAAATCCGAGTATCGCGACCGGCCGGAGTTCTCCGACCCGGCGCAGCCCGTCGTCGCCGTCAACTGG
TTCGACGCCGCCGCCTTCTGCCACTGGCAGGGTGAGCAATGGAACCTGCACCTGCGCCTGCCCACCGAGGCCGAATGGGA
ATTCGCCGCGCGCGGCGGCTTTGCGCAGCGCCTGTACCCGTGGGGCAATGAGCTGCCCGTCATTGCCGCCGATCGCTGGC
GCAACGGCCCGGAACCAGTAGGGCTCGGCGACCCCAACGGCTTCGGCCTTTTCGATCTCTGCCAGAACGTGCATGAGTGG
TGTGCCGATTGGTACGATCCCGGATACTACGCCGTCTCGCCCACTGAAAACCCGCACGGACCCGAACACGGGAAGCGGCG
CGCCTCCCGCGGCGGAGCCTGGCGTCATCACATCAAAGTGTCGCGCTGTGCCGCCAGAAGCAGCATCCCTCCTGAGTTCC
GCTACTCCGACTACGGTTTCCGCGTCGCCGCCCCTTTGTGA

Upstream 100 bases:

>100_bases
CCTTGTGGGGCAGGCAATCTTGCCTGCAGCCGGCTTTCAGCCGGCTTGCCCCGCGCCCACGTGCCTCCTCCCTTTCGCAT
AAGCTCTTAAAAGGTACCCA

Downstream 100 bases:

>100_bases
TTGCGCATATACTGAAGCCGGACGAATTCAGGAGGTAATTGTCGTGAAACTCATATCTTGCTCGTTCGCGGCTCTCACCG
TACTGCTGGTGGGGTGCGGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MTPDDLLPVPGGEFLMGQADGRDEERPPHRVALTPFRLCRYQVTNADYDHFRKATLRDKSEYRDRPEFSDPAQPVVAVNW
FDAAAFCHWQGEQWNLHLRLPTEAEWEFAARGGFAQRLYPWGNELPVIAADRWRNGPEPVGLGDPNGFGLFDLCQNVHEW
CADWYDPGYYAVSPTENPHGPEHGKRRASRGGAWRHHIKVSRCAARSSIPPEFRYSDYGFRVAAPL

Sequences:

>Translated_226_residues
MTPDDLLPVPGGEFLMGQADGRDEERPPHRVALTPFRLCRYQVTNADYDHFRKATLRDKSEYRDRPEFSDPAQPVVAVNW
FDAAAFCHWQGEQWNLHLRLPTEAEWEFAARGGFAQRLYPWGNELPVIAADRWRNGPEPVGLGDPNGFGLFDLCQNVHEW
CADWYDPGYYAVSPTENPHGPEHGKRRASRGGAWRHHIKVSRCAARSSIPPEFRYSDYGFRVAAPL
>Mature_225_residues
TPDDLLPVPGGEFLMGQADGRDEERPPHRVALTPFRLCRYQVTNADYDHFRKATLRDKSEYRDRPEFSDPAQPVVAVNWF
DAAAFCHWQGEQWNLHLRLPTEAEWEFAARGGFAQRLYPWGNELPVIAADRWRNGPEPVGLGDPNGFGLFDLCQNVHEWC
ADWYDPGYYAVSPTENPHGPEHGKRRASRGGAWRHHIKVSRCAARSSIPPEFRYSDYGFRVAAPL

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI257470975, Length=261, Percent_Identity=35.632183908046, Blast_Score=139, Evalue=2e-33,
Organism=Homo sapiens, GI38202250, Length=286, Percent_Identity=32.5174825174825, Blast_Score=132, Evalue=3e-31,
Organism=Homo sapiens, GI257470977, Length=283, Percent_Identity=30.0353356890459, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI194248087, Length=268, Percent_Identity=30.2238805970149, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI194248088, Length=284, Percent_Identity=28.5211267605634, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI226437577, Length=170, Percent_Identity=33.5294117647059, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI194248090, Length=230, Percent_Identity=29.1304347826087, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI20130397, Length=286, Percent_Identity=26.9230769230769, Blast_Score=80, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 25863; Mature: 25732

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPDDLLPVPGGEFLMGQADGRDEERPPHRVALTPFRLCRYQVTNADYDHFRKATLRDKS
CCCCCCCCCCCCCEEEECCCCCCCCCCCCEEEECHHHHHEEEECCCCHHHHHHHHHCCCH
EYRDRPEFSDPAQPVVAVNWFDAAAFCHWQGEQWNLHLRLPTEAEWEFAARGGFAQRLYP
HHCCCCCCCCCCCCEEEEEECCCEEEEEECCCCEEEEEECCCCCCEEHHHCCCCHHHCCC
WGNELPVIAADRWRNGPEPVGLGDPNGFGLFDLCQNVHEWCADWYDPGYYAVSPTENPHG
CCCCCCEEEHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCC
PEHGKRRASRGGAWRHHIKVSRCAARSSIPPEFRYSDYGFRVAAPL
CHHHHHHHHCCCCEEEHHHHHHHHHHCCCCCCCEECCCCEEEECCC
>Mature Secondary Structure 
TPDDLLPVPGGEFLMGQADGRDEERPPHRVALTPFRLCRYQVTNADYDHFRKATLRDKS
CCCCCCCCCCCCEEEECCCCCCCCCCCCEEEECHHHHHEEEECCCCHHHHHHHHHCCCH
EYRDRPEFSDPAQPVVAVNWFDAAAFCHWQGEQWNLHLRLPTEAEWEFAARGGFAQRLYP
HHCCCCCCCCCCCCEEEEEECCCEEEEEECCCCEEEEEECCCCCCEEHHHCCCCHHHCCC
WGNELPVIAADRWRNGPEPVGLGDPNGFGLFDLCQNVHEWCADWYDPGYYAVSPTENPHG
CCCCCCEEEHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCC
PEHGKRRASRGGAWRHHIKVSRCAARSSIPPEFRYSDYGFRVAAPL
CHHHHHHHHCCCCEEEHHHHHHHHHHCCCCCCCEECCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]