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The map label for this gene is ctsA [H]

Identifier: 116622210

GI number: 116622210

Start: 3928473

End: 3929237

Strand: Reverse

Name: ctsA [H]

Synonym: Acid_3102

Alternate gene names: 116622210

Gene position: 3929237-3928473 (Counterclockwise)

Preceding gene: 116622211

Following gene: 116622209

Centisome position: 39.43

GC content: 64.05

Gene sequence:

>765_bases
ATGGATGCCTGGCGTACGGCGATAGCCACTTCTGACGCGACCAGCCTGCGGGTGAGCGGCTACGACATCACGGCGCTGAT
GAAGCTGAGCTTCACCGATACCATCTTCCTTCTGCACCAGGGCCGCTTGCCCAACTCGAACGAACGCAGGCTGCTGGACG
CAATTCTCATCGGAGTTGCCGATCATGGGTCCGGCGCGCCCTCTTGCGCTACCGCAAGACTGGTGGCCTCTGGTAACCGG
CAGTCGCTCTCAGCCGCTGTCGCCGCGGGGATTCTTGCCATTGGGGACGAACACGGCGGGGCGGGCTCCGCCTGCATGGA
ACTGATCGCCGAAGGGGTGGAGCGCAGTTCGCGCGATTCCATCCCGCTGGTGGAAGCGGCTAGCCGAATTACCGCCGAGG
CGATAGCTCAGAAGCGCCGCCTGCCGGGCTTCGGACACCGCGTCCACACACACGACCCTCGCACGGACGTCCTGTTCGAT
ATGGCGCGTGAATCCGGCCTGGCCGGCAAGGGGATCGAGTTCGTCACCGCGCTCGAAGTCGCCATCCGCGAGCAGATCCG
CCCCTTGCCGATCAATATCGATGGTGCGCTCGCGGCCGTCCTGTTCGATATGGGCTTCCCTCCCCTCTTCGGCAAACTGG
TCTTCATCATCGGTCGCGTTGCCGGTCTCAGCGCCGAAGTCGCCGAGGAGTACGCGCGCGAGAAAGCGATGCGGATCCGC
ATTCCGGTGACCTATGATGGGCCGCCTCCACGGGAGATCGAATAA

Upstream 100 bases:

>100_bases
AGGACGCTCGCGGCTCCGATCTGATCCTTGTTTTCGTTAACCGTGCTGCTACCGTTACGCCCGGATTTCCCGTCCCGGCC
TGACTGATAATTGAAGGATC

Downstream 100 bases:

>100_bases
CATGGCAAGGCTCATCACAGACGAGGAAAAACAGGTCGCGCACGAACTGTTGGAACGCGGGCGCGCCGCCATGCAGTGCA
TCGAGAATTACGACCAGGCG

Product: citrate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MDAWRTAIATSDATSLRVSGYDITALMKLSFTDTIFLLHQGRLPNSNERRLLDAILIGVADHGSGAPSCATARLVASGNR
QSLSAAVAAGILAIGDEHGGAGSACMELIAEGVERSSRDSIPLVEAASRITAEAIAQKRRLPGFGHRVHTHDPRTDVLFD
MARESGLAGKGIEFVTALEVAIREQIRPLPINIDGALAAVLFDMGFPPLFGKLVFIIGRVAGLSAEVAEEYAREKAMRIR
IPVTYDGPPPREIE

Sequences:

>Translated_254_residues
MDAWRTAIATSDATSLRVSGYDITALMKLSFTDTIFLLHQGRLPNSNERRLLDAILIGVADHGSGAPSCATARLVASGNR
QSLSAAVAAGILAIGDEHGGAGSACMELIAEGVERSSRDSIPLVEAASRITAEAIAQKRRLPGFGHRVHTHDPRTDVLFD
MARESGLAGKGIEFVTALEVAIREQIRPLPINIDGALAAVLFDMGFPPLFGKLVFIIGRVAGLSAEVAEEYAREKAMRIR
IPVTYDGPPPREIE
>Mature_254_residues
MDAWRTAIATSDATSLRVSGYDITALMKLSFTDTIFLLHQGRLPNSNERRLLDAILIGVADHGSGAPSCATARLVASGNR
QSLSAAVAAGILAIGDEHGGAGSACMELIAEGVERSSRDSIPLVEAASRITAEAIAQKRRLPGFGHRVHTHDPRTDVLFD
MARESGLAGKGIEFVTALEVAIREQIRPLPINIDGALAAVLFDMGFPPLFGKLVFIIGRVAGLSAEVAEEYAREKAMRIR
IPVTYDGPPPREIE

Specific function: Catalyzes The Synthesis Of 2-Methylcitrate From Propionyl-CoA And Oxaloacetate. Also Catalyzes The Condensation Of Oxaloacetate With Acetyl-CoA But With A Lower Specificity. [C]

COG id: COG0372

COG function: function code C; Citrate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the citrate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786527, Length=221, Percent_Identity=28.0542986425339, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016142
- InterPro:   IPR016143
- InterPro:   IPR002020
- InterPro:   IPR016141
- InterPro:   IPR019810 [H]

Pfam domain/function: PF00285 Citrate_synt [H]

EC number: =2.3.3.1 [H]

Molecular weight: Translated: 27093; Mature: 27093

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAWRTAIATSDATSLRVSGYDITALMKLSFTDTIFLLHQGRLPNSNERRLLDAILIGVA
CCCHHHHHCCCCCCEEEECCCCEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHC
DHGSGAPSCATARLVASGNRQSLSAAVAAGILAIGDEHGGAGSACMELIAEGVERSSRDS
CCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHCCCCCC
IPLVEAASRITAEAIAQKRRLPGFGHRVHTHDPRTDVLFDMARESGLAGKGIEFVTALEV
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHH
AIREQIRPLPINIDGALAAVLFDMGFPPLFGKLVFIIGRVAGLSAEVAEEYAREKAMRIR
HHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCEEEE
IPVTYDGPPPREIE
EEEEECCCCCCCCC
>Mature Secondary Structure
MDAWRTAIATSDATSLRVSGYDITALMKLSFTDTIFLLHQGRLPNSNERRLLDAILIGVA
CCCHHHHHCCCCCCEEEECCCCEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHC
DHGSGAPSCATARLVASGNRQSLSAAVAAGILAIGDEHGGAGSACMELIAEGVERSSRDS
CCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHCCCCCC
IPLVEAASRITAEAIAQKRRLPGFGHRVHTHDPRTDVLFDMARESGLAGKGIEFVTALEV
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHH
AIREQIRPLPINIDGALAAVLFDMGFPPLFGKLVFIIGRVAGLSAEVAEEYAREKAMRIR
HHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCEEEE
IPVTYDGPPPREIE
EEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1311544 [H]