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The map label for this gene is frc [H]

Identifier: 116622198

GI number: 116622198

Start: 3910861

End: 3912072

Strand: Direct

Name: frc [H]

Synonym: Acid_3090

Alternate gene names: 116622198

Gene position: 3910861-3912072 (Clockwise)

Preceding gene: 116622196

Following gene: 116622199

Centisome position: 39.24

GC content: 65.1

Gene sequence:

>1212_bases
ATGGCATACCCTCAAGGGGTGCAGCCAGAGAGTACTAACAGCCAGGGACCGCTGGGCGGCATCCGCGTGCTCGACCTGAG
CGCGTACATCGCCGGACCCTATGCGTGTTCCCTCCTCGCCGATCTCGGGGCCGAGGTGATCAAGGTCGAGCCACCGCAGG
GCGACACATTGCGTCACTACCCTTCGACGCTCCCGCAGGAGTCGCGCTGCTTCCTGGGAACCAACCGCGGCAAGCTCGGC
ATCGTCCTCGATCTGAAGCAGGCGGAGGGGCAGGAGGTGATCCTGCGCATGGCCGGCACCGCGGACGTGCTCGTCCACAA
CTTCCGGTCCGGTGTACCCGCCCGGCTCGGCATCGATTATGAACGGCTGCGCCGGGTCAACCCGCGGCTGATCTACTGCG
CCCTGACGGGCTACGGCGACAGCGGACCGCTCAAAAACAAGGCCGGTTACGATCAGGTGCTGCAGAGCATCACGGGAATC
TGTGCCTTGCAGGGTCCGCCGGGTGAGCCGCAGATTGTGTACGGCTCGGTGGTCGATTATTACGCCGCGTCGCAGATCGC
ATTTGGCGTCACCGCCGCGCTCTATCGACGCGAGCACACCGGGGAAGGCCAGTACGTGGGAGTTTCGCTGCTCGCCTCCG
CGCTGGCGATGCAGTCCGGACGCTTCGTCTGGTCGGGGAACGAAGGCCGCGACGTGGGGCGCGATATGCGCTCCGGCGGC
ATCACGGGAATTCATCCCACGCGGAAGGGCTTCATTTACCTCTCGGCCAATACACCGCATTTCTGGCAGGCGCTCTGCGA
ATTGCTTGGATTGCCCGACCTGGCGGAGGACCCCAGGTACAACACGGTGCGCAAACGCGCCCAACGCGCTGCCGAAATCG
TACCCCGAATGCGCGCCGTCCTCAGCGGCCGTACCGCGCTGGAGTGGGAGCAGGTGTTCGGCGAACGCGTACCTTGCGGC
GCGATCCGGCCGATCGAGGACATGTTCGATCATCCGCAGGTTCTCGCCGAAGGTCTGGTAACCGAATTCGAACATCCAAA
CGTTGGCCGCTATCGCGGCATGGCGAAGCCAGTGCAGTTCAGCGAGACGCCGTGCGTCGATCCCTACGCCGCGCCCGCTC
TCGGCCAGCACACCGCGGAGGTCCTGGCGCGCTACGGCTACTCCGAACAGGAAGTGCGGCGGCTGCGAGAATTCGGCGTC
ATCCCTGCTTGA

Upstream 100 bases:

>100_bases
AACAGGCGCCAGATGAAGGGGAGGAAAGGTACTTGAAAATACAAGCCTGAACTGTGAAGAATGTTACCACTCGCGGGCGA
GCGCGTCAAGATCTACTCCG

Downstream 100 bases:

>100_bases
TATGGAACCGCTCAACGAACAACTCATCGAACGTATCGACGCCTATATCGAGGCGCTCTTCACTCCGCCCGACGCGGTTC
TCTCCGAGAACCTGGCCGAC

Product: Formyl-CoA transferase

Products: NA

Alternate protein names: Formyl-CoA transferase [H]

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MAYPQGVQPESTNSQGPLGGIRVLDLSAYIAGPYACSLLADLGAEVIKVEPPQGDTLRHYPSTLPQESRCFLGTNRGKLG
IVLDLKQAEGQEVILRMAGTADVLVHNFRSGVPARLGIDYERLRRVNPRLIYCALTGYGDSGPLKNKAGYDQVLQSITGI
CALQGPPGEPQIVYGSVVDYYAASQIAFGVTAALYRREHTGEGQYVGVSLLASALAMQSGRFVWSGNEGRDVGRDMRSGG
ITGIHPTRKGFIYLSANTPHFWQALCELLGLPDLAEDPRYNTVRKRAQRAAEIVPRMRAVLSGRTALEWEQVFGERVPCG
AIRPIEDMFDHPQVLAEGLVTEFEHPNVGRYRGMAKPVQFSETPCVDPYAAPALGQHTAEVLARYGYSEQEVRRLREFGV
IPA

Sequences:

>Translated_403_residues
MAYPQGVQPESTNSQGPLGGIRVLDLSAYIAGPYACSLLADLGAEVIKVEPPQGDTLRHYPSTLPQESRCFLGTNRGKLG
IVLDLKQAEGQEVILRMAGTADVLVHNFRSGVPARLGIDYERLRRVNPRLIYCALTGYGDSGPLKNKAGYDQVLQSITGI
CALQGPPGEPQIVYGSVVDYYAASQIAFGVTAALYRREHTGEGQYVGVSLLASALAMQSGRFVWSGNEGRDVGRDMRSGG
ITGIHPTRKGFIYLSANTPHFWQALCELLGLPDLAEDPRYNTVRKRAQRAAEIVPRMRAVLSGRTALEWEQVFGERVPCG
AIRPIEDMFDHPQVLAEGLVTEFEHPNVGRYRGMAKPVQFSETPCVDPYAAPALGQHTAEVLARYGYSEQEVRRLREFGV
IPA
>Mature_402_residues
AYPQGVQPESTNSQGPLGGIRVLDLSAYIAGPYACSLLADLGAEVIKVEPPQGDTLRHYPSTLPQESRCFLGTNRGKLGI
VLDLKQAEGQEVILRMAGTADVLVHNFRSGVPARLGIDYERLRRVNPRLIYCALTGYGDSGPLKNKAGYDQVLQSITGIC
ALQGPPGEPQIVYGSVVDYYAASQIAFGVTAALYRREHTGEGQYVGVSLLASALAMQSGRFVWSGNEGRDVGRDMRSGGI
TGIHPTRKGFIYLSANTPHFWQALCELLGLPDLAEDPRYNTVRKRAQRAAEIVPRMRAVLSGRTALEWEQVFGERVPCGA
IRPIEDMFDHPQVLAEGLVTEFEHPNVGRYRGMAKPVQFSETPCVDPYAAPALGQHTAEVLARYGYSEQEVRRLREFGVI
PA

Specific function: Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate [H]

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=403, Percent_Identity=32.258064516129, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI300863124, Length=429, Percent_Identity=30.3030303030303, Blast_Score=199, Evalue=3e-51,
Organism=Homo sapiens, GI300863126, Length=399, Percent_Identity=30.5764411027569, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI13376042, Length=429, Percent_Identity=27.7389277389277, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI266456254, Length=398, Percent_Identity=29.1457286432161, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI42794625, Length=398, Percent_Identity=29.1457286432161, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI266458393, Length=262, Percent_Identity=32.824427480916, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI266458397, Length=259, Percent_Identity=32.4324324324324, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI42822893, Length=142, Percent_Identity=40.1408450704225, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI266458395, Length=142, Percent_Identity=40.1408450704225, Blast_Score=91, Evalue=3e-18,
Organism=Escherichia coli, GI87082093, Length=384, Percent_Identity=29.4270833333333, Blast_Score=178, Evalue=4e-46,
Organism=Escherichia coli, GI1788717, Length=418, Percent_Identity=29.4258373205742, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1786222, Length=400, Percent_Identity=25.75, Blast_Score=115, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI32564160, Length=329, Percent_Identity=25.531914893617, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI115535051, Length=324, Percent_Identity=25.3086419753086, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24648431, Length=401, Percent_Identity=35.6608478802993, Blast_Score=214, Evalue=7e-56,
Organism=Drosophila melanogaster, GI24585488, Length=323, Percent_Identity=30.3405572755418, Blast_Score=124, Evalue=9e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673
- InterPro:   IPR017659 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: =2.8.3.16 [H]

Molecular weight: Translated: 44030; Mature: 43899

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYPQGVQPESTNSQGPLGGIRVLDLSAYIAGPYACSLLADLGAEVIKVEPPQGDTLRHY
CCCCCCCCCCCCCCCCCCCCEEEEEEHHHHCCHHHHHHHHHCCCCEEEECCCCCCCHHHC
PSTLPQESRCFLGTNRGKLGIVLDLKQAEGQEVILRMAGTADVLVHNFRSGVPARLGIDY
CCCCCCCCCEEEECCCCCEEEEEEECCCCCCEEEEEECCHHHHHHHHHHCCCCCEECCCH
ERLRRVNPRLIYCALTGYGDSGPLKNKAGYDQVLQSITGICALQGPPGEPQIVYGSVVDY
HHHHCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHCEEEECCCCCCCEEEECHHHHH
YAASQIAFGVTAALYRREHTGEGQYVGVSLLASALAMQSGRFVWSGNEGRDVGRDMRSGG
HHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCC
ITGIHPTRKGFIYLSANTPHFWQALCELLGLPDLAEDPRYNTVRKRAQRAAEIVPRMRAV
CCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LSGRTALEWEQVFGERVPCGAIRPIEDMFDHPQVLAEGLVTEFEHPNVGRYRGMAKPVQF
HCCCCHHHHHHHHCCCCCCCCCCCHHHHHCCHHHHHHHHHHHCCCCCCHHHCCCCCCCCC
SETPCVDPYAAPALGQHTAEVLARYGYSEQEVRRLREFGVIPA
CCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCC
>Mature Secondary Structure 
AYPQGVQPESTNSQGPLGGIRVLDLSAYIAGPYACSLLADLGAEVIKVEPPQGDTLRHY
CCCCCCCCCCCCCCCCCCCEEEEEEHHHHCCHHHHHHHHHCCCCEEEECCCCCCCHHHC
PSTLPQESRCFLGTNRGKLGIVLDLKQAEGQEVILRMAGTADVLVHNFRSGVPARLGIDY
CCCCCCCCCEEEECCCCCEEEEEEECCCCCCEEEEEECCHHHHHHHHHHCCCCCEECCCH
ERLRRVNPRLIYCALTGYGDSGPLKNKAGYDQVLQSITGICALQGPPGEPQIVYGSVVDY
HHHHCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHCEEEECCCCCCCEEEECHHHHH
YAASQIAFGVTAALYRREHTGEGQYVGVSLLASALAMQSGRFVWSGNEGRDVGRDMRSGG
HHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCC
ITGIHPTRKGFIYLSANTPHFWQALCELLGLPDLAEDPRYNTVRKRAQRAAEIVPRMRAV
CCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LSGRTALEWEQVFGERVPCGAIRPIEDMFDHPQVLAEGLVTEFEHPNVGRYRGMAKPVQF
HCCCCHHHHHHHHCCCCCCCCCCCHHHHHCCHHHHHHHHHHHCCCCCCHHHCCCCCCCCC
SETPCVDPYAAPALGQHTAEVLARYGYSEQEVRRLREFGVIPA
CCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]