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The map label for this gene is yccK [H]

Identifier: 116622024

GI number: 116622024

Start: 3689983

End: 3690966

Strand: Direct

Name: yccK [H]

Synonym: Acid_2909

Alternate gene names: 116622024

Gene position: 3689983-3690966 (Clockwise)

Preceding gene: 116622023

Following gene: 116622025

Centisome position: 37.03

GC content: 58.43

Gene sequence:

>984_bases
ATGCAAAAGCGAAACCTGGGAAAGAGCGGGCTGGAAGTGTCAGCCCTTGGCTTCGGCTGCATGGGCCTCAGCTTCGGCTT
TGGCCCGGCTACCGAGAAGAGTGAGGCGATCAAGGTAATCCGCGCCGCTTATGACGGCGGCGTGACCTTCTTTGATACCG
CCGAGGCATACGGTCCGTTTACCAACGAGGAGCTGGTCGGCGAAGCGCTGGCTCCGATTCGCGACAAGGTAGTCATCGCC
ACCAAATTCGGCTTCGAAAGCGGAGTGCCAAACCAGGGCACGAACAGCAAGCCGGAACGGATCAGGGCGGTGGCGGAAGC
GGCGCTGAAGCGCCTGAATACCGGTGTGATCGATCTGTTCTATCAGCACCGGGTGGACCCGAATGTGCCCATTGAAGATG
TCGCCGGCACAGTCAGGGATCTGATTCGGGAGGGCAAGGTAAGGCACTTCGGTATGTCGGAAGCCGGTGCGGAGAACATT
CGTCGCGCTCACCGCGTGCAGCCGGTTACAGCTCTTCAGAGTGAGTACTCGCTGTGGTGGCGGGAGCCGGAGAAGGAGAT
TCTGCCGACACTGGAGGAACTCGGCATCGGCTTTGTCCCGTTCAGCCCGCTGGGAAAGGGTTTTCTGACCGGAGCCATTT
CCGAAAAGACAGAGTTCGATAAGAGTGACTTCCGTAATATCGTTCCGCGCTTTTCCGCGGAAGCGCGAAAAGCGAACATG
GCACTGGTGGATGTTCTTGGGAAGATCGCGGAGCAGAAGAAGGCGACGAAAGCGCAGATCGCCCTCGCCTGGCTGCTCGC
TCAGAAGCCGTGGATTGTTCCGATTCCCGGAACCACCAAGCTGCATCGCGTGCAAGAGAATCTGGGCGGCGCGGAAGTGG
AACTGACACCGGAAGAGTTGCAAACCATTCACCAGGCCATCTCCGAAATCGAGGTTCAAGGAGACCGATATCCGGCTCAC
TACCAAAATCTGGTCAACCGGTAG

Upstream 100 bases:

>100_bases
TCAGGGCGCGCGGATGGGGCGAGGCATTTTGTCGCTCTCCGGTGTGGAAGCGCCTGCAAAGCAGAGATGACCAGTAGCTG
CTAGAAAGGAAGGAAGAACC

Downstream 100 bases:

>100_bases
GTCTTGCTTGCGACCGGTCACGGCTTTGGTCCTCTTACTGCTCGCGAACGTGGACGACGTGATTGCAAAAGACGCGGGTC
ATTTAGGAGCGCAGAATACC

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MQKRNLGKSGLEVSALGFGCMGLSFGFGPATEKSEAIKVIRAAYDGGVTFFDTAEAYGPFTNEELVGEALAPIRDKVVIA
TKFGFESGVPNQGTNSKPERIRAVAEAALKRLNTGVIDLFYQHRVDPNVPIEDVAGTVRDLIREGKVRHFGMSEAGAENI
RRAHRVQPVTALQSEYSLWWREPEKEILPTLEELGIGFVPFSPLGKGFLTGAISEKTEFDKSDFRNIVPRFSAEARKANM
ALVDVLGKIAEQKKATKAQIALAWLLAQKPWIVPIPGTTKLHRVQENLGGAEVELTPEELQTIHQAISEIEVQGDRYPAH
YQNLVNR

Sequences:

>Translated_327_residues
MQKRNLGKSGLEVSALGFGCMGLSFGFGPATEKSEAIKVIRAAYDGGVTFFDTAEAYGPFTNEELVGEALAPIRDKVVIA
TKFGFESGVPNQGTNSKPERIRAVAEAALKRLNTGVIDLFYQHRVDPNVPIEDVAGTVRDLIREGKVRHFGMSEAGAENI
RRAHRVQPVTALQSEYSLWWREPEKEILPTLEELGIGFVPFSPLGKGFLTGAISEKTEFDKSDFRNIVPRFSAEARKANM
ALVDVLGKIAEQKKATKAQIALAWLLAQKPWIVPIPGTTKLHRVQENLGGAEVELTPEELQTIHQAISEIEVQGDRYPAH
YQNLVNR
>Mature_327_residues
MQKRNLGKSGLEVSALGFGCMGLSFGFGPATEKSEAIKVIRAAYDGGVTFFDTAEAYGPFTNEELVGEALAPIRDKVVIA
TKFGFESGVPNQGTNSKPERIRAVAEAALKRLNTGVIDLFYQHRVDPNVPIEDVAGTVRDLIREGKVRHFGMSEAGAENI
RRAHRVQPVTALQSEYSLWWREPEKEILPTLEELGIGFVPFSPLGKGFLTGAISEKTEFDKSDFRNIVPRFSAEARKANM
ALVDVLGKIAEQKKATKAQIALAWLLAQKPWIVPIPGTTKLHRVQENLGGAEVELTPEELQTIHQAISEIEVQGDRYPAH
YQNLVNR

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436971, Length=319, Percent_Identity=30.7210031347962, Blast_Score=128, Evalue=9e-30,
Organism=Homo sapiens, GI27436964, Length=308, Percent_Identity=31.1688311688312, Blast_Score=121, Evalue=7e-28,
Organism=Homo sapiens, GI27436962, Length=308, Percent_Identity=31.1688311688312, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI27436966, Length=308, Percent_Identity=31.1688311688312, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI27436969, Length=307, Percent_Identity=28.9902280130293, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI4504825, Length=304, Percent_Identity=28.9473684210526, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI223718702, Length=202, Percent_Identity=31.1881188118812, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI41152114, Length=202, Percent_Identity=30.1980198019802, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI41327764, Length=162, Percent_Identity=30.8641975308642, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI87081735, Length=312, Percent_Identity=33.3333333333333, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1789375, Length=331, Percent_Identity=30.8157099697885, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1788070, Length=338, Percent_Identity=29.2899408284024, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1787674, Length=302, Percent_Identity=29.1390728476821, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1788081, Length=309, Percent_Identity=25.8899676375405, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1789199, Length=352, Percent_Identity=27.8409090909091, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI48994888, Length=287, Percent_Identity=26.8292682926829, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6325169, Length=335, Percent_Identity=29.5522388059701, Blast_Score=128, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6325384, Length=337, Percent_Identity=27.893175074184, Blast_Score=116, Evalue=6e-27,
Organism=Saccharomyces cerevisiae, GI6323998, Length=326, Percent_Identity=26.6871165644172, Blast_Score=106, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6319958, Length=296, Percent_Identity=24.6621621621622, Blast_Score=100, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6319951, Length=299, Percent_Identity=24.7491638795987, Blast_Score=96, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6322615, Length=251, Percent_Identity=24.3027888446215, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24640980, Length=319, Percent_Identity=24.1379310344828, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI45549126, Length=319, Percent_Identity=24.1379310344828, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24646155, Length=158, Percent_Identity=32.9113924050633, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24646159, Length=222, Percent_Identity=25.6756756756757, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36022; Mature: 36022

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKRNLGKSGLEVSALGFGCMGLSFGFGPATEKSEAIKVIRAAYDGGVTFFDTAEAYGPF
CCCCCCCCCCCEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCEEEEECHHHCCCC
TNEELVGEALAPIRDKVVIATKFGFESGVPNQGTNSKPERIRAVAEAALKRLNTGVIDLF
CCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHH
YQHRVDPNVPIEDVAGTVRDLIREGKVRHFGMSEAGAENIRRAHRVQPVTALQSEYSLWW
HHHCCCCCCCHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
REPEKEILPTLEELGIGFVPFSPLGKGFLTGAISEKTEFDKSDFRNIVPRFSAEARKANM
CCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
ALVDVLGKIAEQKKATKAQIALAWLLAQKPWIVPIPGTTKLHRVQENLGGAEVELTPEEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCCEEEECHHHH
QTIHQAISEIEVQGDRYPAHYQNLVNR
HHHHHHHHHHHHCCCCCCHHHHHHHCC
>Mature Secondary Structure
MQKRNLGKSGLEVSALGFGCMGLSFGFGPATEKSEAIKVIRAAYDGGVTFFDTAEAYGPF
CCCCCCCCCCCEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCEEEEECHHHCCCC
TNEELVGEALAPIRDKVVIATKFGFESGVPNQGTNSKPERIRAVAEAALKRLNTGVIDLF
CCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHH
YQHRVDPNVPIEDVAGTVRDLIREGKVRHFGMSEAGAENIRRAHRVQPVTALQSEYSLWW
HHHCCCCCCCHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
REPEKEILPTLEELGIGFVPFSPLGKGFLTGAISEKTEFDKSDFRNIVPRFSAEARKANM
CCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
ALVDVLGKIAEQKKATKAQIALAWLLAQKPWIVPIPGTTKLHRVQENLGGAEVELTPEEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCCEEEECHHHH
QTIHQAISEIEVQGDRYPAHYQNLVNR
HHHHHHHHHHHHCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]