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The map label for this gene is lytR [H]

Identifier: 116622021

GI number: 116622021

Start: 3686423

End: 3687178

Strand: Direct

Name: lytR [H]

Synonym: Acid_2906

Alternate gene names: 116622021

Gene position: 3686423-3687178 (Clockwise)

Preceding gene: 116622020

Following gene: 116622022

Centisome position: 36.99

GC content: 60.98

Gene sequence:

>756_bases
ATGAAACGATTCCGGCTCTTAATCGTTGATGACGAACCACTGATCCGCGCCGGCATCCGTGACGGCCTTTCCGGCAGGGA
CGACATCGAAGTCGCCGGCGAGTGCGGAAGCGTTTCGGAAGCGGTAGACCTCCTGCGTTCGGACGAAGTAGACCTGGTTT
TGCTCGATGTAGAACTGCCCGATGGCAAGGGTTTCGACGTGATCCGGCGGGTTGGGACGTACCGGATGCCAGCGGTCGTG
TTCGTGACGGCATACGACAAGTACGCCATTCAGGCATTTGAAGTGAACGCCGTGGACTATCTGCTAAAACCCTTCGACCA
GAGCCGTCTGCTGGCGAGTCTGGATCGAGTCAGGGACCGGCTGGCCGGGGCAGGAGAATCGCTGGCGCGGCGGCTCGAAG
CGCTGATTCAATCGCGTGAAACGCAGTGGCCGCAGACGCTCGTCGTACGCCAGGGTGAGCGGTACGATTTGATCTCGGTG
ACGTCTGTGGACTGGATCGAAGCGGCGAATAACTACGCTGTCCTGCACTGCGGGACGGTGGACCATGTTTTCGGCGAGAC
GCTGGCTAGCCTGGAGACGCGACTCGATCCAGCGAAGTTCCTGCGCGTGCATCGATCGGTGATTGTAAACTCGGCGCGCA
TTGTCGCGGTGCACACGATGATTGGCGGCGTCTACGAGTTGGAATTGCGGGGCGGCACGCGCGTCAAGACCGGGCGGCAG
TACCGCGATCGAATCCGCAAGCTGCTCGGCGCGTGA

Upstream 100 bases:

>100_bases
CGGCACGGGTTCTCCATACGCCGGTTGCAGGAGGGCGGAACCGAGGTCCGCATTACGCTACCATTGCGGTTTACCAACTC
AGTCCGTCATACCCGCGCGC

Downstream 100 bases:

>100_bases
GGCGGGACTCGCTGCTCGCCTCGGGATTGGTGTGGTTCACCAGCTAGCGCGGGGTGTTCGCCAGGAACCAGATGTAAATA
TCAAGCGCGGGCCGCATGAT

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MKRFRLLIVDDEPLIRAGIRDGLSGRDDIEVAGECGSVSEAVDLLRSDEVDLVLLDVELPDGKGFDVIRRVGTYRMPAVV
FVTAYDKYAIQAFEVNAVDYLLKPFDQSRLLASLDRVRDRLAGAGESLARRLEALIQSRETQWPQTLVVRQGERYDLISV
TSVDWIEAANNYAVLHCGTVDHVFGETLASLETRLDPAKFLRVHRSVIVNSARIVAVHTMIGGVYELELRGGTRVKTGRQ
YRDRIRKLLGA

Sequences:

>Translated_251_residues
MKRFRLLIVDDEPLIRAGIRDGLSGRDDIEVAGECGSVSEAVDLLRSDEVDLVLLDVELPDGKGFDVIRRVGTYRMPAVV
FVTAYDKYAIQAFEVNAVDYLLKPFDQSRLLASLDRVRDRLAGAGESLARRLEALIQSRETQWPQTLVVRQGERYDLISV
TSVDWIEAANNYAVLHCGTVDHVFGETLASLETRLDPAKFLRVHRSVIVNSARIVAVHTMIGGVYELELRGGTRVKTGRQ
YRDRIRKLLGA
>Mature_251_residues
MKRFRLLIVDDEPLIRAGIRDGLSGRDDIEVAGECGSVSEAVDLLRSDEVDLVLLDVELPDGKGFDVIRRVGTYRMPAVV
FVTAYDKYAIQAFEVNAVDYLLKPFDQSRLLASLDRVRDRLAGAGESLARRLEALIQSRETQWPQTLVVRQGERYDLISV
TSVDWIEAANNYAVLHCGTVDHVFGETLASLETRLDPAKFLRVHRSVIVNSARIVAVHTMIGGVYELELRGGTRVKTGRQ
YRDRIRKLLGA

Specific function: Member of the two-component regulatory system lytR/lytS that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082052, Length=250, Percent_Identity=33.2, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1788724, Length=245, Percent_Identity=24.0816326530612, Blast_Score=95, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 28126; Mature: 28126

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRFRLLIVDDEPLIRAGIRDGLSGRDDIEVAGECGSVSEAVDLLRSDEVDLVLLDVELP
CCCEEEEEECCCHHHHHHHHCCCCCCCCEEECCCCCCHHHHHHHHHCCCCCEEEEEEECC
DGKGFDVIRRVGTYRMPAVVFVTAYDKYAIQAFEVNAVDYLLKPFDQSRLLASLDRVRDR
CCCCHHHHHHHCCCCCCEEEEEEECCCEEEEEEEEHHHHHHHCCCCHHHHHHHHHHHHHH
LAGAGESLARRLEALIQSRETQWPQTLVVRQGERYDLISVTSVDWIEAANNYAVLHCGTV
HCCCCHHHHHHHHHHHHHHCCCCCHHHEEECCCCEEEEEECCCHHHHCCCCEEEEEECCH
DHVFGETLASLETRLDPAKFLRVHRSVIVNSARIVAVHTMIGGVYELELRGGTRVKTGRQ
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHEEEEEEHHCCEEEEEECCCCCCCCCHH
YRDRIRKLLGA
HHHHHHHHHCC
>Mature Secondary Structure
MKRFRLLIVDDEPLIRAGIRDGLSGRDDIEVAGECGSVSEAVDLLRSDEVDLVLLDVELP
CCCEEEEEECCCHHHHHHHHCCCCCCCCEEECCCCCCHHHHHHHHHCCCCCEEEEEEECC
DGKGFDVIRRVGTYRMPAVVFVTAYDKYAIQAFEVNAVDYLLKPFDQSRLLASLDRVRDR
CCCCHHHHHHHCCCCCCEEEEEEECCCEEEEEEEEHHHHHHHCCCCHHHHHHHHHHHHHH
LAGAGESLARRLEALIQSRETQWPQTLVVRQGERYDLISVTSVDWIEAANNYAVLHCGTV
HCCCCHHHHHHHHHHHHHHCCCCCHHHEEECCCCEEEEEECCCHHHHCCCCEEEEEECCH
DHVFGETLASLETRLDPAKFLRVHRSVIVNSARIVAVHTMIGGVYELELRGGTRVKTGRQ
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHEEEEEEHHCCEEEEEECCCCCCCCCHH
YRDRIRKLLGA
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA