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The map label for this gene is nreC [H]

Identifier: 116621985

GI number: 116621985

Start: 3631015

End: 3631665

Strand: Direct

Name: nreC [H]

Synonym: Acid_2870

Alternate gene names: 116621985

Gene position: 3631015-3631665 (Clockwise)

Preceding gene: 116621984

Following gene: 116621991

Centisome position: 36.44

GC content: 62.06

Gene sequence:

>651_bases
ATGAAGCCGATTCGTATCTTGTTGGCTGACGACCACACGGTGGTCCGCGACGGCCTGCGCGCCCTGCTCGAGCGTGAGGA
CGACATGACCGTTGTGGGTGAAGCGGCCGACGGACGCGAAAGCATCCGCATGGCCGAGACCGAATCGCCCGACGTGGTGG
TGATGGACCTGGCGATGCCGAATATGAACGGCATGGAGGCAACGCGCCGCATTCTGGCATCAACCTCGTGCGCCGGCGTC
GTGATCCTCAGCATGCATTCCGACGAGAGCTATGTGCTCGGCGCGCTCAAGGCCGGCGCCAAGGGCTACCTGCTGAAAGA
TTCGATGCGCGGCGAAGTGATCCAGGCCATCCGCGCCGTGTCGGAAGGACGATCTTTCCTGACGAAGAAAATCGCGCGCA
TCATGCAGGAGGATTACGTCAGCCGCCTGCAGCAGCGCGGCCTCGAGGACCGCTACGACCTGCTCAGCGACCGAGAGCGT
GAAGTGCTCCAGATGATCGCCGAGGGCCGCTCCAACAAGGAGGTCGCCAACCTCCTGAATATCAGCCCGACCACGGTCGA
GACGCATCGCGCCCACATCCTGCAAAAGCTGGACATTCATAGCGTACCCGAGTTAATCCTCTACGCCGTGCGCAAGGGCA
TCATCTCCTGA

Upstream 100 bases:

>100_bases
CGACGCCTGGGAGGACGTTTGAAGATTACATCGGAGCCGGGCCGCGGCACCCTGGTGCACGCGGCGCTGCCGCTATCGGA
CCTGGAAAAAAGGAACGGAC

Downstream 100 bases:

>100_bases
ACTGGCTAGCCGCCCTGGCCGCCGCCAGGGACCGGGAGCCCATCGACCGGGGCATCGATTACCTTCTGCGAAAGCGTGTA
CTGCCAGGCGTCGATGATGC

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MKPIRILLADDHTVVRDGLRALLEREDDMTVVGEAADGRESIRMAETESPDVVVMDLAMPNMNGMEATRRILASTSCAGV
VILSMHSDESYVLGALKAGAKGYLLKDSMRGEVIQAIRAVSEGRSFLTKKIARIMQEDYVSRLQQRGLEDRYDLLSDRER
EVLQMIAEGRSNKEVANLLNISPTTVETHRAHILQKLDIHSVPELILYAVRKGIIS

Sequences:

>Translated_216_residues
MKPIRILLADDHTVVRDGLRALLEREDDMTVVGEAADGRESIRMAETESPDVVVMDLAMPNMNGMEATRRILASTSCAGV
VILSMHSDESYVLGALKAGAKGYLLKDSMRGEVIQAIRAVSEGRSFLTKKIARIMQEDYVSRLQQRGLEDRYDLLSDRER
EVLQMIAEGRSNKEVANLLNISPTTVETHRAHILQKLDIHSVPELILYAVRKGIIS
>Mature_216_residues
MKPIRILLADDHTVVRDGLRALLEREDDMTVVGEAADGRESIRMAETESPDVVVMDLAMPNMNGMEATRRILASTSCAGV
VILSMHSDESYVLGALKAGAKGYLLKDSMRGEVIQAIRAVSEGRSFLTKKIARIMQEDYVSRLQQRGLEDRYDLLSDRER
EVLQMIAEGRSNKEVANLLNISPTTVETHRAHILQKLDIHSVPELILYAVRKGIIS

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=213, Percent_Identity=37.0892018779343, Blast_Score=152, Evalue=1e-38,
Organism=Escherichia coli, GI1788521, Length=212, Percent_Identity=35.377358490566, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1790102, Length=202, Percent_Identity=34.1584158415842, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1786747, Length=209, Percent_Identity=29.6650717703349, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1787473, Length=188, Percent_Identity=35.6382978723404, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1788712, Length=208, Percent_Identity=26.9230769230769, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI1788546, Length=211, Percent_Identity=26.0663507109005, Blast_Score=79, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24072; Mature: 24072

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPIRILLADDHTVVRDGLRALLEREDDMTVVGEAADGRESIRMAETESPDVVVMDLAMP
CCCEEEEEECCHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHEECCCCCCCEEEEEECCC
NMNGMEATRRILASTSCAGVVILSMHSDESYVLGALKAGAKGYLLKDSMRGEVIQAIRAV
CCCHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHCCCCCEEECCHHHHHHHHHHHHH
SEGRSFLTKKIARIMQEDYVSRLQQRGLEDRYDLLSDREREVLQMIAEGRSNKEVANLLN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHC
ISPTTVETHRAHILQKLDIHSVPELILYAVRKGIIS
CCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKPIRILLADDHTVVRDGLRALLEREDDMTVVGEAADGRESIRMAETESPDVVVMDLAMP
CCCEEEEEECCHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHEECCCCCCCEEEEEECCC
NMNGMEATRRILASTSCAGVVILSMHSDESYVLGALKAGAKGYLLKDSMRGEVIQAIRAV
CCCHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHCCCCCEEECCHHHHHHHHHHHHH
SEGRSFLTKKIARIMQEDYVSRLQQRGLEDRYDLLSDREREVLQMIAEGRSNKEVANLLN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHC
ISPTTVETHRAHILQKLDIHSVPELILYAVRKGIIS
CCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12426351 [H]