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The map label for this gene is nreB [H]

Identifier: 116621984

GI number: 116621984

Start: 3629655

End: 3631043

Strand: Direct

Name: nreB [H]

Synonym: Acid_2869

Alternate gene names: 116621984

Gene position: 3629655-3631043 (Clockwise)

Preceding gene: 116621982

Following gene: 116621985

Centisome position: 36.42

GC content: 64.07

Gene sequence:

>1389_bases
GTGCAGTCTCACCCGGGTAGTCAGGTTGCCGTTTCCGAAGAGAAGCGCCGCAGGCCTTCGTGGCTGATTTTGTCCCTCGG
TTTCGGCGGACTCCTGACCTGTATCGTTGTGGCTGCGGTTGGCACCCTGGCGGCGCTGGACCGGGTACGCAGTAATGAGG
TGCATTCCCGCAAGATGTTTCTCGAGCGGCTCAGCGCGCTCGACCAGATCCGCGCGCAAATCTACCTCTCCGGCACCTAC
GTGCGCGATTTCCTGCTCTCGCCGGATCCGCTGACGGCCCAGGCGCAGGCCGCGCACCTCGGACCATTGGAGCGCGACAC
CCACAACGCGATTGAAGCTTACCGCCGCAATCTGGAGCCCGAAGAGCGCGAGCCGTTTCTGGCGCTCCGCAAGGAAATCG
AGGCCTACTGGCAGGTGCTCGACACCACCGTGGGGTGGACCCAACAGGATCGCGATCGCCTGCGATTTTCGTTCTTCTAT
AACGAACTGGTGCCGCGCCGCACCGCGATGCTGCAGATCGCGGACCGCATCGCGCTGGTCAATGAACGCGGTCTCACCCG
CTCCGAAGGACAGTCGGCCTCTGCCGCCGGGAACTTGCGGCGATACCTGATGCTGACCTTCGCAGGCACTCTCGGCGGCG
GCCTGATTCTGGCGCTGGTGACCATCGCCTTCACGCTGCGGCTGGAGCGCGAACTGGAATTGCGCAGGTCGGATTTGCAG
GAGCTTTCGACTCTGCTCCTGCGCGCGCAGGAGAACGAGCGCCGCGCGCTGGCGCGCGAGCTTCACGATGAGATCGGCCA
ATCGCTCTCGGCGATCCTCATGGAAACCGAGGGCGCCGAATGCGCGGAACGCCGCGCCGATCTGAGCAGCCATCTCGATT
CGATCAAGGGGCTGGCGGAGAAGACCGTCAACCAGGTACGCGATCTGGCGCTGCTTTTGCGGCCTTCGATGCTGGACGAC
CTGGGCCTGGCGCCGGCTTTGAACTGGCATGCACGCGAGACCAGCAAGCGCACCGGCCTGAACGTGGTGGTCTCCGCGGA
CGACGCGATCGACGATCTTCCCGACGAGCACCGCACCTGCATTTACCGCCTGGTGCAGGAGGCGGTCAACAACGCGGTCC
GCCACGCCAATGCGCGCACAGTCGATGTGTCGGTTCGCAAGGAAGGACATAAGGTGAACGTGACTGTGCGGGATAACGGC
GCGGGGTTCGACACGCGCTTCCTGCGCGGCCTCGGACTGTTGGGCATGGAGGAGCGCGTACGACGCCTGGGAGGACGTTT
GAAGATTACATCGGAGCCGGGCCGCGGCACCCTGGTGCACGCGGCGCTGCCGCTATCGGACCTGGAAAAAAGGAACGGAC
ATGAAGCCGATTCGTATCTTGTTGGCTGA

Upstream 100 bases:

>100_bases
AATCCTTTCTTGAAATGATTGAAACACCATTGCACCTCTCAGTGAAATCCTGTCCGCACAGTATTTCTTCGTACCTCAGC
CTGGTCTACACTCAAGAAAA

Downstream 100 bases:

>100_bases
CGACCACACGGTGGTCCGCGACGGCCTGCGCGCCCTGCTCGAGCGTGAGGACGACATGACCGTTGTGGGTGAAGCGGCCG
ACGGACGCGAAAGCATCCGC

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Nitrogen regulation protein B [H]

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MQSHPGSQVAVSEEKRRRPSWLILSLGFGGLLTCIVVAAVGTLAALDRVRSNEVHSRKMFLERLSALDQIRAQIYLSGTY
VRDFLLSPDPLTAQAQAAHLGPLERDTHNAIEAYRRNLEPEEREPFLALRKEIEAYWQVLDTTVGWTQQDRDRLRFSFFY
NELVPRRTAMLQIADRIALVNERGLTRSEGQSASAAGNLRRYLMLTFAGTLGGGLILALVTIAFTLRLERELELRRSDLQ
ELSTLLLRAQENERRALARELHDEIGQSLSAILMETEGAECAERRADLSSHLDSIKGLAEKTVNQVRDLALLLRPSMLDD
LGLAPALNWHARETSKRTGLNVVVSADDAIDDLPDEHRTCIYRLVQEAVNNAVRHANARTVDVSVRKEGHKVNVTVRDNG
AGFDTRFLRGLGLLGMEERVRRLGGRLKITSEPGRGTLVHAALPLSDLEKRNGHEADSYLVG

Sequences:

>Translated_462_residues
MQSHPGSQVAVSEEKRRRPSWLILSLGFGGLLTCIVVAAVGTLAALDRVRSNEVHSRKMFLERLSALDQIRAQIYLSGTY
VRDFLLSPDPLTAQAQAAHLGPLERDTHNAIEAYRRNLEPEEREPFLALRKEIEAYWQVLDTTVGWTQQDRDRLRFSFFY
NELVPRRTAMLQIADRIALVNERGLTRSEGQSASAAGNLRRYLMLTFAGTLGGGLILALVTIAFTLRLERELELRRSDLQ
ELSTLLLRAQENERRALARELHDEIGQSLSAILMETEGAECAERRADLSSHLDSIKGLAEKTVNQVRDLALLLRPSMLDD
LGLAPALNWHARETSKRTGLNVVVSADDAIDDLPDEHRTCIYRLVQEAVNNAVRHANARTVDVSVRKEGHKVNVTVRDNG
AGFDTRFLRGLGLLGMEERVRRLGGRLKITSEPGRGTLVHAALPLSDLEKRNGHEADSYLVG
>Mature_462_residues
MQSHPGSQVAVSEEKRRRPSWLILSLGFGGLLTCIVVAAVGTLAALDRVRSNEVHSRKMFLERLSALDQIRAQIYLSGTY
VRDFLLSPDPLTAQAQAAHLGPLERDTHNAIEAYRRNLEPEEREPFLALRKEIEAYWQVLDTTVGWTQQDRDRLRFSFFY
NELVPRRTAMLQIADRIALVNERGLTRSEGQSASAAGNLRRYLMLTFAGTLGGGLILALVTIAFTLRLERELELRRSDLQ
ELSTLLLRAQENERRALARELHDEIGQSLSAILMETEGAECAERRADLSSHLDSIKGLAEKTVNQVRDLALLLRPSMLDD
LGLAPALNWHARETSKRTGLNVVVSADDAIDDLPDEHRTCIYRLVQEAVNNAVRHANARTVDVSVRKEGHKVNVTVRDNG
AGFDTRFLRGLGLLGMEERVRRLGGRLKITSEPGRGTLVHAALPLSDLEKRNGHEADSYLVG

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxyg

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI87082311, Length=211, Percent_Identity=36.0189573459716, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787474, Length=194, Percent_Identity=29.8969072164948, Blast_Score=76, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR017203 [H]

Pfam domain/function: PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 51640; Mature: 51640

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSHPGSQVAVSEEKRRRPSWLILSLGFGGLLTCIVVAAVGTLAALDRVRSNEVHSRKMF
CCCCCCCCEEECHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
LERLSALDQIRAQIYLSGTYVRDFLLSPDPLTAQAQAAHLGPLERDTHNAIEAYRRNLEP
HHHHHHHHHHHHHHEECHHHHHHHHCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHCCCC
EEREPFLALRKEIEAYWQVLDTTVGWTQQDRDRLRFSFFYNELVPRRTAMLQIADRIALV
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NERGLTRSEGQSASAAGNLRRYLMLTFAGTLGGGLILALVTIAFTLRLERELELRRSDLQ
HCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELSTLLLRAQENERRALARELHDEIGQSLSAILMETEGAECAERRADLSSHLDSIKGLAE
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
KTVNQVRDLALLLRPSMLDDLGLAPALNWHARETSKRTGLNVVVSADDAIDDLPDEHRTC
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCEEEEECCHHHHCCCCHHHHH
IYRLVQEAVNNAVRHANARTVDVSVRKEGHKVNVTVRDNGAGFDTRFLRGLGLLGMEERV
HHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEECCCCCCHHHHHHHCCCCCHHHHH
RRLGGRLKITSEPGRGTLVHAALPLSDLEKRNGHEADSYLVG
HHCCCEEEEECCCCCCEEEEEECCHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MQSHPGSQVAVSEEKRRRPSWLILSLGFGGLLTCIVVAAVGTLAALDRVRSNEVHSRKMF
CCCCCCCCEEECHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
LERLSALDQIRAQIYLSGTYVRDFLLSPDPLTAQAQAAHLGPLERDTHNAIEAYRRNLEP
HHHHHHHHHHHHHHEECHHHHHHHHCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHCCCC
EEREPFLALRKEIEAYWQVLDTTVGWTQQDRDRLRFSFFYNELVPRRTAMLQIADRIALV
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NERGLTRSEGQSASAAGNLRRYLMLTFAGTLGGGLILALVTIAFTLRLERELELRRSDLQ
HCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELSTLLLRAQENERRALARELHDEIGQSLSAILMETEGAECAERRADLSSHLDSIKGLAE
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
KTVNQVRDLALLLRPSMLDDLGLAPALNWHARETSKRTGLNVVVSADDAIDDLPDEHRTC
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCEEEEECCHHHHCCCCHHHHH
IYRLVQEAVNNAVRHANARTVDVSVRKEGHKVNVTVRDNGAGFDTRFLRGLGLLGMEERV
HHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEECCCCCCHHHHHHHCCCCCHHHHH
RRLGGRLKITSEPGRGTLVHAALPLSDLEKRNGHEADSYLVG
HHCCCEEEEECCCCCCEEEEEECCHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12426351 [H]