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The map label for this gene is yrpG [H]

Identifier: 116621978

GI number: 116621978

Start: 3624704

End: 3625735

Strand: Direct

Name: yrpG [H]

Synonym: Acid_2863

Alternate gene names: 116621978

Gene position: 3624704-3625735 (Clockwise)

Preceding gene: 116621977

Following gene: 116621981

Centisome position: 36.37

GC content: 65.31

Gene sequence:

>1032_bases
ATGGAATATCGGTTGTTAGGTGCCAGCGGCCTCCAAGTCTCGGTGCTCAGCTTCGGCACCATGACTCTCGGCGGCGAGGG
ACGTTTCGCCGCCATGGGCAACGTGCAGGTGGAAGAAGCCCGCCGCCAGATCGAGATCTGCATCGAAGCGGGCGTCAACC
TCTTCGACACCGCCGACATCTACTCTTTCGGCAAATCCGAGGAGGTGCTCGGCCAGGCCCTCGGTGCCCTCCGCAAGGAC
ATCGTCCTCGCCACCAAAGTCTTCGTCGGCCTCGAACCCGGCGCCAACAAGTCCGGCCTCACCCGCCGCCACATCATGGA
AGCCTGCGAGGCCAGCCTCCGCCGCCTCGGAACCGATACCATCGACCTCTACCAGGCGCACAACTTCGACGCCCTCACCC
CGCTCGAGGAAACCCTTCGTGCCTTCGACGACCTGATCCGCTCCGGCAAGATTCGCTACGCCGGCTGTTCGAACTATTCC
GGCTGGCAGCTCATGAAGGCCCACTCCACCTCCGACCGCCTCGCCGTCCAGCGGTATATCTCGCAGCAGATCAACTACTC
CCTGCTGGCCCGCGATGCCGAGCACGAACTCGTGCCTGCGGGCCTGGACCAGCACACCGGCATCATGGCCTGGAGCCCTC
TCCAGTTCGGCCTCCTGTCTGGCAAATTCCGCCGCGGCCAGGCCAAGCCCTCCGAGTCGCGCCTCAACACTCTCGACGCG
CCCGGCACCATCGATGAGGAGCGTCTGTACCGCATCGTCGACGCCCTCGCCGAAATCGCCGCCGTCCGCAACGTCTCCGT
CTCTCAGGTCGCGCTAAATTGGGTGACCTGCAAGCCCGGCGTCGATACCGTCATCATCGGCGCCCGTACCGACCAGCAAC
TCCGCGATAACCTCGCCGCCGCCGCCTGGCGCCTCACCCCCGCCGAAGTCGAACGCCTCGACGAAGTCAGCGCCCTGCCC
TTGCCATACCCCTACTGGCACCAACAAAAATTCGCCGCCGACCGCAACCCTCCGCTCCCCCACACCCGCTGA

Upstream 100 bases:

>100_bases
AAGCGGGCTACGCGGCCCGCTTTTTTGGTGTAACTCCCTTGTTTTCAATGAATGTTTTCGAAAACCGGGCCAAGTATGGC
CCACTTTTGAGGAAAGTGCC

Downstream 100 bases:

>100_bases
CGAGCCGATCGCCTTGACCCCGCCTGCGGCGCCATCACCGCTCGTCGTCACCGCGAACCGCGACCCTCAGGGAGCGATCT
CAACTTTCACGGCCGCGGCG

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MEYRLLGASGLQVSVLSFGTMTLGGEGRFAAMGNVQVEEARRQIEICIEAGVNLFDTADIYSFGKSEEVLGQALGALRKD
IVLATKVFVGLEPGANKSGLTRRHIMEACEASLRRLGTDTIDLYQAHNFDALTPLEETLRAFDDLIRSGKIRYAGCSNYS
GWQLMKAHSTSDRLAVQRYISQQINYSLLARDAEHELVPAGLDQHTGIMAWSPLQFGLLSGKFRRGQAKPSESRLNTLDA
PGTIDEERLYRIVDALAEIAAVRNVSVSQVALNWVTCKPGVDTVIIGARTDQQLRDNLAAAAWRLTPAEVERLDEVSALP
LPYPYWHQQKFAADRNPPLPHTR

Sequences:

>Translated_343_residues
MEYRLLGASGLQVSVLSFGTMTLGGEGRFAAMGNVQVEEARRQIEICIEAGVNLFDTADIYSFGKSEEVLGQALGALRKD
IVLATKVFVGLEPGANKSGLTRRHIMEACEASLRRLGTDTIDLYQAHNFDALTPLEETLRAFDDLIRSGKIRYAGCSNYS
GWQLMKAHSTSDRLAVQRYISQQINYSLLARDAEHELVPAGLDQHTGIMAWSPLQFGLLSGKFRRGQAKPSESRLNTLDA
PGTIDEERLYRIVDALAEIAAVRNVSVSQVALNWVTCKPGVDTVIIGARTDQQLRDNLAAAAWRLTPAEVERLDEVSALP
LPYPYWHQQKFAADRNPPLPHTR
>Mature_343_residues
MEYRLLGASGLQVSVLSFGTMTLGGEGRFAAMGNVQVEEARRQIEICIEAGVNLFDTADIYSFGKSEEVLGQALGALRKD
IVLATKVFVGLEPGANKSGLTRRHIMEACEASLRRLGTDTIDLYQAHNFDALTPLEETLRAFDDLIRSGKIRYAGCSNYS
GWQLMKAHSTSDRLAVQRYISQQINYSLLARDAEHELVPAGLDQHTGIMAWSPLQFGLLSGKFRRGQAKPSESRLNTLDA
PGTIDEERLYRIVDALAEIAAVRNVSVSQVALNWVTCKPGVDTVIIGARTDQQLRDNLAAAAWRLTPAEVERLDEVSALP
LPYPYWHQQKFAADRNPPLPHTR

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=327, Percent_Identity=33.0275229357798, Blast_Score=161, Evalue=7e-40,
Organism=Homo sapiens, GI27436962, Length=309, Percent_Identity=33.9805825242718, Blast_Score=161, Evalue=7e-40,
Organism=Homo sapiens, GI27436966, Length=309, Percent_Identity=33.6569579288026, Blast_Score=158, Evalue=6e-39,
Organism=Homo sapiens, GI27436969, Length=309, Percent_Identity=33.9805825242718, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI4504825, Length=307, Percent_Identity=33.8762214983713, Blast_Score=155, Evalue=4e-38,
Organism=Homo sapiens, GI27436971, Length=327, Percent_Identity=31.1926605504587, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI223718702, Length=297, Percent_Identity=29.96632996633, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI41327764, Length=291, Percent_Identity=29.553264604811, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI41152114, Length=296, Percent_Identity=28.7162162162162, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI87081735, Length=320, Percent_Identity=35.9375, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI1789199, Length=361, Percent_Identity=32.409972299169, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1789375, Length=314, Percent_Identity=30.8917197452229, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1788070, Length=336, Percent_Identity=30.3571428571429, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1788081, Length=296, Percent_Identity=32.7702702702703, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI48994888, Length=277, Percent_Identity=27.7978339350181, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI212645785, Length=327, Percent_Identity=26.2996941896024, Blast_Score=78, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6325169, Length=337, Percent_Identity=28.1899109792285, Blast_Score=147, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6323998, Length=326, Percent_Identity=27.6073619631902, Blast_Score=117, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6319958, Length=303, Percent_Identity=26.4026402640264, Blast_Score=110, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6319951, Length=331, Percent_Identity=26.2839879154079, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6322615, Length=257, Percent_Identity=25.6809338521401, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6321052, Length=158, Percent_Identity=30.379746835443, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24640980, Length=321, Percent_Identity=27.1028037383178, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI45549126, Length=321, Percent_Identity=27.1028037383178, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24646155, Length=333, Percent_Identity=30.03003003003, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24646159, Length=319, Percent_Identity=30.4075235109718, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37897; Mature: 37897

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS00104 EPSP_SYNTHASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYRLLGASGLQVSVLSFGTMTLGGEGRFAAMGNVQVEEARRQIEICIEAGVNLFDTADI
CCEEEECCCCCEEEEEEECEEEECCCCCEEEECCCCHHHHHHHHHHHHHCCCCCEECHHH
YSFGKSEEVLGQALGALRKDIVLATKVFVGLEPGANKSGLTRRHIMEACEASLRRLGTDT
HHCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
IDLYQAHNFDALTPLEETLRAFDDLIRSGKIRYAGCSNYSGWQLMKAHSTSDRLAVQRYI
EEHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEECCCHHHHHHHHHH
SQQINYSLLARDAEHELVPAGLDQHTGIMAWSPLQFGLLSGKFRRGQAKPSESRLNTLDA
HHHCCHHHEECCCCCCCCCCCCCCCCCEEEECCHHHHHHCCCCCCCCCCCCHHHHCCCCC
PGTIDEERLYRIVDALAEIAAVRNVSVSQVALNWVTCKPGVDTVIIGARTDQQLRDNLAA
CCCCCHHHHHHHHHHHHHHHHHHCCCHHHEEEEEEEECCCCCEEEEECCCCHHHHHHHHH
AAWRLTPAEVERLDEVSALPLPYPYWHQQKFAADRNPPLPHTR
HHHCCCHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCCC
>Mature Secondary Structure
MEYRLLGASGLQVSVLSFGTMTLGGEGRFAAMGNVQVEEARRQIEICIEAGVNLFDTADI
CCEEEECCCCCEEEEEEECEEEECCCCCEEEECCCCHHHHHHHHHHHHHCCCCCEECHHH
YSFGKSEEVLGQALGALRKDIVLATKVFVGLEPGANKSGLTRRHIMEACEASLRRLGTDT
HHCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
IDLYQAHNFDALTPLEETLRAFDDLIRSGKIRYAGCSNYSGWQLMKAHSTSDRLAVQRYI
EEHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEECCCHHHHHHHHHH
SQQINYSLLARDAEHELVPAGLDQHTGIMAWSPLQFGLLSGKFRRGQAKPSESRLNTLDA
HHHCCHHHEECCCCCCCCCCCCCCCCCEEEECCHHHHHHCCCCCCCCCCCCHHHHCCCCC
PGTIDEERLYRIVDALAEIAAVRNVSVSQVALNWVTCKPGVDTVIIGARTDQQLRDNLAA
CCCCCHHHHHHHHHHHHHHHHHHCCCHHHEEEEEEEECCCCCEEEEECCCCHHHHHHHHH
AAWRLTPAEVERLDEVSALPLPYPYWHQQKFAADRNPPLPHTR
HHHCCCHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9308178; 9384377 [H]