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The map label for this gene is mntH [H]

Identifier: 116621843

GI number: 116621843

Start: 3455120

End: 3456412

Strand: Reverse

Name: mntH [H]

Synonym: Acid_2725

Alternate gene names: 116621843

Gene position: 3456412-3455120 (Counterclockwise)

Preceding gene: 116621845

Following gene: 116621842

Centisome position: 34.68

GC content: 64.73

Gene sequence:

>1293_bases
ATGAATCTACTCGTGCAAACGCCCACGAAGGTGCGCGTGGTGCGCAGCCGCTGGGCTCGCGATCTGCTCACGTTTCTGAT
GGTCTGCGGTCCGGGCCTGATCGTCATGGAAGCCGACAATGACGCCGGCGCGGTCTCCACCTACGCGCAGGCTGGCGCGC
AGCATGGCACTCACCTGCTGTGGCTGCTGGCGATCCTGCTGCCCGTGACTTACTTCGTGCAGGAGATGGTGGTCCGCCTG
GGTATCGCCACCGGCCAGGGACACGCCGCGATGATCTATCAGCGCTTCGGCAAGTGGTGGGGCCGCTTCTCGCTGGTCGA
TCTGCAGCTCGTGAACTTCCTGACGCTGGTAACCGAGTTCGCCGCTATCGCGCTGGCGCTCGAGCGCCTCGGCGTGCGTC
CGCTCTTCGGAGTTCCCGCAGCCGCCATCGCGCTCACAGCCCTGGTCTTCACCGGCGGCTACCGGCGTTGGGAGCGGATT
GTCGTGTCTCTCTGCCTGCTCGACGCGGCATGGCTGGTGCTGGCGTGGAAACTCGGACCCGGCGCCGGCCAGGTGCTTCG
CCACACCGTACCCGCAATGCCGCGCGGCGGCATCAGCACCGGCCTGGTCTTCCTGGTGATCGGGATCGTCGGCACCACTA
TCGCGCCGTGGCAGCTCTTTTTTCAGCAAAGCTCCATCGCCGATAAGCGTCTGCGCTTCGCCGACCTGAAGTTCTCGCGC
CTCGATACGCTTTTGGGCGCTGTCTTTACCGTTGCGATCGCCGGTTGCATGATGCTTGCCGGCGACGCCGCGCTGCGCCA
CGGAATCCGCTTCACGGATCCCGCTCAGATGGCGGTGGACCTGGGACGCATCTTCGGACCGTGGGTGAAGAACTCCATCC
TTCTGTTGATGATCAACGCTGCCGCGCTCGGCACCACCACCATTTCACTTTCCAGCGCGTGGGCCTACGGCGAAGTGGCC
GGTTGGGACCACAGCCTGGAAAAATCGCCGCGCGAGGCCCCGCGCTTCTATGCGGTCTACGCCGCGTGCGTCGCTGCGGC
CGCCGGACTGGTGCTGATCCCCGGCGCGCCGCTGCAACTGATCATTGTGAGCGTGCAGGTGCTCGCCGGGCTCATGCTGC
CCTCGACGATCGTCTTCCTGCAGCTCTTGCTGAACGACCGCGAACTGCTCGGCCCGGAGTTCGCCAACAAGCCGTGGAAC
AACGTACTCAATTGGAGCATCGTGTTTGTGCTGTTGGTGCTCTCGCTGATTTTGGCGGCGCAGGTGATCGCGCCCGGACT
GTTTCCCGCATGA

Upstream 100 bases:

>100_bases
TATCCTCATCCCGCTAGCCGGGACCCTTCTTCTTTGCTTTCGACCATTGCGCCCGAACCTTGTCCGCTCTCGGACAGGTA
CGGACTGATGGGAAAGCCTA

Downstream 100 bases:

>100_bases
GGAGGTGAATCATGAAAAGAGAATTCCAAGTGGTGCACCCGCTCGACGACGTTCGCGAGCGCAAAATCGACATATCCGGA
CTCGGACCGATGCGAATGAC

Product: natural resistance-associated macrophage protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MNLLVQTPTKVRVVRSRWARDLLTFLMVCGPGLIVMEADNDAGAVSTYAQAGAQHGTHLLWLLAILLPVTYFVQEMVVRL
GIATGQGHAAMIYQRFGKWWGRFSLVDLQLVNFLTLVTEFAAIALALERLGVRPLFGVPAAAIALTALVFTGGYRRWERI
VVSLCLLDAAWLVLAWKLGPGAGQVLRHTVPAMPRGGISTGLVFLVIGIVGTTIAPWQLFFQQSSIADKRLRFADLKFSR
LDTLLGAVFTVAIAGCMMLAGDAALRHGIRFTDPAQMAVDLGRIFGPWVKNSILLLMINAAALGTTTISLSSAWAYGEVA
GWDHSLEKSPREAPRFYAVYAACVAAAAGLVLIPGAPLQLIIVSVQVLAGLMLPSTIVFLQLLLNDRELLGPEFANKPWN
NVLNWSIVFVLLVLSLILAAQVIAPGLFPA

Sequences:

>Translated_430_residues
MNLLVQTPTKVRVVRSRWARDLLTFLMVCGPGLIVMEADNDAGAVSTYAQAGAQHGTHLLWLLAILLPVTYFVQEMVVRL
GIATGQGHAAMIYQRFGKWWGRFSLVDLQLVNFLTLVTEFAAIALALERLGVRPLFGVPAAAIALTALVFTGGYRRWERI
VVSLCLLDAAWLVLAWKLGPGAGQVLRHTVPAMPRGGISTGLVFLVIGIVGTTIAPWQLFFQQSSIADKRLRFADLKFSR
LDTLLGAVFTVAIAGCMMLAGDAALRHGIRFTDPAQMAVDLGRIFGPWVKNSILLLMINAAALGTTTISLSSAWAYGEVA
GWDHSLEKSPREAPRFYAVYAACVAAAAGLVLIPGAPLQLIIVSVQVLAGLMLPSTIVFLQLLLNDRELLGPEFANKPWN
NVLNWSIVFVLLVLSLILAAQVIAPGLFPA
>Mature_430_residues
MNLLVQTPTKVRVVRSRWARDLLTFLMVCGPGLIVMEADNDAGAVSTYAQAGAQHGTHLLWLLAILLPVTYFVQEMVVRL
GIATGQGHAAMIYQRFGKWWGRFSLVDLQLVNFLTLVTEFAAIALALERLGVRPLFGVPAAAIALTALVFTGGYRRWERI
VVSLCLLDAAWLVLAWKLGPGAGQVLRHTVPAMPRGGISTGLVFLVIGIVGTTIAPWQLFFQQSSIADKRLRFADLKFSR
LDTLLGAVFTVAIAGCMMLAGDAALRHGIRFTDPAQMAVDLGRIFGPWVKNSILLLMINAAALGTTTISLSSAWAYGEVA
GWDHSLEKSPREAPRFYAVYAACVAAAAGLVLIPGAPLQLIIVSVQVLAGLMLPSTIVFLQLLLNDRELLGPEFANKPWN
NVLNWSIVFVLLVLSLILAAQVIAPGLFPA

Specific function: H(+)-stimulated, highly selective, manganese uptake system [H]

COG id: COG1914

COG function: function code P; Mn2+ and Fe2+ transporters of the NRAMP family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NRAMP family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023056
- InterPro:   IPR001046 [H]

Pfam domain/function: PF01566 Nramp [H]

EC number: NA

Molecular weight: Translated: 46474; Mature: 46474

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS00626 RCC1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCCCCCC
>Mature Secondary Structure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HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA