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The map label for this gene is bgaC [H]

Identifier: 116517213

GI number: 116517213

Start: 65845

End: 67632

Strand: Direct

Name: bgaC [H]

Synonym: SPD_0065

Alternate gene names: 116517213

Gene position: 65845-67632 (Clockwise)

Preceding gene: 116516623

Following gene: 116516149

Centisome position: 3.22

GC content: 41.89

Gene sequence:

>1788_bases
ATGACACGATTTGAGATACGAGATGATTTCTATCTCGATGGAAAATCATTTAAGATTTTATCTGGTGCCATTCATTATTT
TAGGATTCCTCCAGAGGATTGGTATCATTCGCTCTATAACTTGAAGGCTCTTGGTTTTAATACGGTAGAGACTTATGTTG
CTTGGAATTTACACGAGCCTCGTGAAGGTGAGTTTCATTTTGAAGGTGATCTGGATTTAGAGAAATTTCTCCAAATAGCG
CAGGATTTGGGTCTCTACGCAATTGTGCGTCCGTCTCCATTTATCTGTGCGGAATGGGAATTCGGTGGCTTACCAGCTTG
GCTCTTGACCAAGAACATGCGAATTCGCTCATCCGACCCAGCATATATCGAGGCAGTTGGTCGCTACTATGATCAGTTAT
TGCCAAGACTGGTGCCTCGTTTGTTGAACAATGGTGGCAATATTCTCATGATGCAGGTTGAAAATGAGTATGGTTCTTAC
GGAGAAGATAAGGCTTACCTGAGAGCGATTCGACAGCTAATGGAAGAGTGTGGCGTAACCTGTCCCCTCTTTACATCAGA
TGGTCCATGGCGAGCTACTCTGAAAGCTGGAACCTTAATTGAAGAGGACCTCTTTGTAACAGGAAACTTTGGTTCTAAGG
CACCTTACAACTTTTCGCAGATGCAGGAATTCTTTGATGAACATGGTAAGAAATGGCCACTCATGTGTATGGAGTTCTGG
GATGGTTGGTTCAATCGCTGGAAAGAACCGATTATCACACGGGATCCTAAGGAATTGGCAGATGCAGTTCGAGAGGTTTT
GGAACAAGGCTCTATCAATCTTTACATGTTCCACGGTGGTACAAACTTTGGTTTCATGAATGGTTGCTCAGCTCGAGGAA
CTTTGGACCTGCCACAAGTTACATCTTATGATTACGATGCCCTTCTGGATGAAGAAGGAAATCCAACTGCTAAATATCTT
GCAGTCAAGAAGATGATGGCAACACATTTTTCAGAGTATCCGCAGTTGGAACCACTCTACAAAGAGAGTATGGAGTTGGA
TGCTATTCCACTAGTTGAAAAAGTTTCTTTGTTTGAAACCTTAGATAGCTTGTCAAGTCCTGTAGAAAGTCTCTATCCTC
AAAAGATGGAGGAGCTGGGACAAAGTTATGGCTACCTACTTTATCGAACAGAAACAAACTGGGATGCAGAAGAAGAAAGA
CTTCGTATCATTGATGGTCGAGATAGGGCCCAGCTGTATGTCGATGGTCAGTGGGTTAAAACTCAATATCAGACAGAGAT
TGGGGAAGATATTTTTTATCAAGGTAAAAAGAAAGGGCTATCTAGGTTAGATATCTTGATAGAAAATATGGGGCGTGTCA
ACTATGGGCATAAGTTCTTAGCGGATACGCAACGTAAGGGAATTCGGACAGGGGTCTGTAAGGATCTGCATTTCTTACTA
AACTGGAAACACTATCCACTCCCACTAGACAATCCTGAGAAAATTGATTTTTCAAAAGGATGGACTCAAGGACAACCAGC
CTTTTACGCTTATGACTTTACAGTCGAAGAGCCAAAAGATACTTACCTAGACTTGTCTGAGTTTGGTAAGGGAGTTGCCT
TTGTCAATGGGCAGAATCTAGGACGTTTTTGGAACGTTGGCCCAACTCTCTCACTTTATATCCCTCATAGCTATCTCAAG
GAAGGTGCCAACCGTATCATTATCTTTGAAACAGAAGGTCAATATAAAGAAGAGATTCATTTAACTCGTAAACCTACACT
AAAACATATAAAGGGGGAAAACTTATGA

Upstream 100 bases:

>100_bases
AAATATCCCGACAATTTCTATTGACAATTCAAACAGATTGGTTTATAATTAATATAACAACAAATGAAAGCGCAAACTTT
CGCGGTCGGAAGGTAGTTTT

Downstream 100 bases:

>100_bases
CAATTGTAGGATGCCGTATTGATGGACGTTTGATCCACGGACAAGTAGCCAATCTTTGGGCTGGAAAACTAAATGTTTCA
CGCATTATGGTTGTAGACGA

Product: Beta-galactosidase 3

Products: NA

Alternate protein names: Lactase [H]

Number of amino acids: Translated: 595; Mature: 594

Protein sequence:

>595_residues
MTRFEIRDDFYLDGKSFKILSGAIHYFRIPPEDWYHSLYNLKALGFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIA
QDLGLYAIVRPSPFICAEWEFGGLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLNNGGNILMMQVENEYGSY
GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNFSQMQEFFDEHGKKWPLMCMEFW
DGWFNRWKEPIITRDPKELADAVREVLEQGSINLYMFHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYL
AVKKMMATHFSEYPQLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTETNWDAEEER
LRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENMGRVNYGHKFLADTQRKGIRTGVCKDLHFLL
NWKHYPLPLDNPEKIDFSKGWTQGQPAFYAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLK
EGANRIIIFETEGQYKEEIHLTRKPTLKHIKGENL

Sequences:

>Translated_595_residues
MTRFEIRDDFYLDGKSFKILSGAIHYFRIPPEDWYHSLYNLKALGFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIA
QDLGLYAIVRPSPFICAEWEFGGLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLNNGGNILMMQVENEYGSY
GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNFSQMQEFFDEHGKKWPLMCMEFW
DGWFNRWKEPIITRDPKELADAVREVLEQGSINLYMFHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYL
AVKKMMATHFSEYPQLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTETNWDAEEER
LRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENMGRVNYGHKFLADTQRKGIRTGVCKDLHFLL
NWKHYPLPLDNPEKIDFSKGWTQGQPAFYAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLK
EGANRIIIFETEGQYKEEIHLTRKPTLKHIKGENL
>Mature_594_residues
TRFEIRDDFYLDGKSFKILSGAIHYFRIPPEDWYHSLYNLKALGFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQ
DLGLYAIVRPSPFICAEWEFGGLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLNNGGNILMMQVENEYGSYG
EDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNFSQMQEFFDEHGKKWPLMCMEFWD
GWFNRWKEPIITRDPKELADAVREVLEQGSINLYMFHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLA
VKKMMATHFSEYPQLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTETNWDAEEERL
RIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENMGRVNYGHKFLADTQRKGIRTGVCKDLHFLLN
WKHYPLPLDNPEKIDFSKGWTQGQPAFYAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKE
GANRIIIFETEGQYKEEIHLTRKPTLKHIKGENL

Specific function: Preferentially hydrolyzes beta(1->3) galactosyl linkages over beta(1->4) linkages [H]

COG id: COG1874

COG function: function code G; Beta-galactosidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 35 family [H]

Homologues:

Organism=Homo sapiens, GI31543093, Length=606, Percent_Identity=38.6138613861386, Blast_Score=373, Evalue=1e-103,
Organism=Homo sapiens, GI164519026, Length=610, Percent_Identity=37.8688524590164, Blast_Score=354, Evalue=1e-97,
Organism=Homo sapiens, GI119372312, Length=608, Percent_Identity=37.0065789473684, Blast_Score=342, Evalue=7e-94,
Organism=Homo sapiens, GI119372308, Length=608, Percent_Identity=37.0065789473684, Blast_Score=342, Evalue=7e-94,
Organism=Homo sapiens, GI40255043, Length=603, Percent_Identity=35.9867330016584, Blast_Score=328, Evalue=6e-90,
Organism=Homo sapiens, GI208022658, Length=372, Percent_Identity=32.258064516129, Blast_Score=162, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI72000600, Length=601, Percent_Identity=36.4392678868552, Blast_Score=313, Evalue=1e-85,
Organism=Caenorhabditis elegans, GI17568491, Length=611, Percent_Identity=30.7692307692308, Blast_Score=244, Evalue=7e-65,
Organism=Drosophila melanogaster, GI24582088, Length=605, Percent_Identity=38.1818181818182, Blast_Score=358, Evalue=4e-99,
Organism=Drosophila melanogaster, GI24646169, Length=616, Percent_Identity=34.9025974025974, Blast_Score=327, Evalue=1e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008979
- InterPro:   IPR019801
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR001944 [H]

Pfam domain/function: PF01301 Glyco_hydro_35 [H]

EC number: =3.2.1.23 [H]

Molecular weight: Translated: 69011; Mature: 68880

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRFEIRDDFYLDGKSFKILSGAIHYFRIPPEDWYHSLYNLKALGFNTVETYVAWNLHEP
CCEEEECCCEEECCCCEEEEECCEEEEECCCHHHHHHHHHHHCCCCCCEEEEEEECCCCC
REGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFGGLPAWLLTKNMRIRSSDP
CCCCEEECCCCCHHHHHHHHHHCCEEEEECCCCCEEECCCCCCCCHHHHCCCCEEECCCC
AYIEAVGRYYDQLLPRLVPRLLNNGGNILMMQVENEYGSYGEDKAYLRAIRQLMEECGVT
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCE
CPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNFSQMQEFFDEHGKKWPLMCMEFW
EEEECCCCCEEEEEECCCEEECCEEEECCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHH
DGWFNRWKEPIITRDPKELADAVREVLEQGSINLYMFHGGTNFGFMNGCSARGTLDLPQV
HHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCC
TSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYPQLEPLYKESMELDAIPLVEKVSLFET
CCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCHHHHHHHHHH
LDSLSSPVESLYPQKMEELGQSYGYLLYRTETNWDAEEERLRIIDGRDRAQLYVDGQWVK
HHHHHCCHHHHCHHHHHHHHHHCCEEEEEECCCCCCCCCCEEEECCCCCEEEEECCEEEE
TQYQTEIGEDIFYQGKKKGLSRLDILIENMGRVNYGHKFLADTQRKGIRTGVCKDLHFLL
EHHHHHHCHHHHHCCHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHH
NWKHYPLPLDNPEKIDFSKGWTQGQPAFYAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNL
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCEEEHHHCCCCEEEECCCCC
GRFWNVGPTLSLYIPHSYLKEGANRIIIFETEGQYKEEIHLTRKPTLKHIKGENL
CCEECCCCEEEEEECHHHHHCCCCEEEEEECCCCCCHHEEECCCCHHHCCCCCCC
>Mature Secondary Structure 
TRFEIRDDFYLDGKSFKILSGAIHYFRIPPEDWYHSLYNLKALGFNTVETYVAWNLHEP
CEEEECCCEEECCCCEEEEECCEEEEECCCHHHHHHHHHHHCCCCCCEEEEEEECCCCC
REGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFGGLPAWLLTKNMRIRSSDP
CCCCEEECCCCCHHHHHHHHHHCCEEEEECCCCCEEECCCCCCCCHHHHCCCCEEECCCC
AYIEAVGRYYDQLLPRLVPRLLNNGGNILMMQVENEYGSYGEDKAYLRAIRQLMEECGVT
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCE
CPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNFSQMQEFFDEHGKKWPLMCMEFW
EEEECCCCCEEEEEECCCEEECCEEEECCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHH
DGWFNRWKEPIITRDPKELADAVREVLEQGSINLYMFHGGTNFGFMNGCSARGTLDLPQV
HHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCC
TSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYPQLEPLYKESMELDAIPLVEKVSLFET
CCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCHHHHHHHHHH
LDSLSSPVESLYPQKMEELGQSYGYLLYRTETNWDAEEERLRIIDGRDRAQLYVDGQWVK
HHHHHCCHHHHCHHHHHHHHHHCCEEEEEECCCCCCCCCCEEEECCCCCEEEEECCEEEE
TQYQTEIGEDIFYQGKKKGLSRLDILIENMGRVNYGHKFLADTQRKGIRTGVCKDLHFLL
EHHHHHHCHHHHHCCHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHH
NWKHYPLPLDNPEKIDFSKGWTQGQPAFYAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNL
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCEEEHHHCCCCEEEECCCCC
GRFWNVGPTLSLYIPHSYLKEGANRIIIFETEGQYKEEIHLTRKPTLKHIKGENL
CCEECCCCEEEEEECHHHHHCCCCEEEEEECCCCCCHHEEECCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8563148 [H]