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The map label for this gene is yheS [H]

Identifier: 116517191

GI number: 116517191

Start: 1170469

End: 1172028

Strand: Direct

Name: yheS [H]

Synonym: SPD_1137

Alternate gene names: 116517191

Gene position: 1170469-1172028 (Clockwise)

Preceding gene: 116515975

Following gene: 116516833

Centisome position: 57.2

GC content: 39.87

Gene sequence:

>1560_bases
ATGCACTATGAACATTCTAGAAAGGGAAATCATATGATAAAAATCAATCATCTAACCATCACACAAAACAAAGATTTACG
AGATCTTGTATCTGACCTAACCATGACCATCCAAGACGGGGAAAAGGTAGCTATTATTGGCGAAGAAGGAAATGGTAAAT
CAACCTTACTTAAAACTTTAATGGGGGAAGATTTGTCTGATTTCACTATCAAGGGAGACATCCAGTCTGATTATCAGTCA
CTGGCCTACATTCCTCAAAAAGTCCCTGAGGACCTAAAAAAGAAAACTTTACACGACTACTTCTTTTTAGATTCTATTGA
TTTAGACTACAGTATCCTCTATCGTTTGGCGGAGGAATTGCATTTTGATAGCAATCGTTTCGCAAGTGACCAAGAGATTG
GCAATCTATCAGGGGGCGAAGCTTTGAAAATTCAGCTTATCCATGAGTTAGCCAAACCCTTTGAGATTCTATTTTTAGAT
GAACCTTCAAATGACCTAGACCTTGAGACAGTTGATTGGCTAAAAGGCCAGATTCAAAAGACCAGGCAAACCGTTATTTT
CATTTCCCATGATGAAGACTTTCTTTCTGAAACGGCAGACACTATTGTTCACTTGCGACTGGTCAAACACCGTAAAGAAG
CGGAAACGCTAGTAGAGCATTTAGACTATGATAGCTATAGTGAGCAGAGAAAGGCTAATTTTGCCAAACAAAGTCAGCAA
GCTGCTAACAACCAAAGAGCCTACGATAAAACCATGAAAAAACATCGGAGAGTCAAGCAAAATGTAGAAACTGCGCTTCG
AGCTACCAAAGATAGTACTGCCGGTCGCCTATTGGCTAAAAAGATGAAAACTGTCCTCTCACAAGAAAAACGCTACGAAA
AGGCAGCTCAGTCCATGACTCAAAAGCCACTTGAAGAGGAACAAATCCAACTTTTCTTTTCAGACATCCAACCATTACCA
GCTTCTAAAGTCTTAGTCCAACTGGAAAAAGAAAATTTGTCCATTGACGACCGAGTTTTGGTTCAAAAACTACAACTAAC
TGTCCGTGGGCAAGAAAAAATCGGTATTATCGGGCCAAATGGTGTTGGGAAATCAACTCTGTTAGCCAAATTAAAGCAAC
TTCTGAATGATAAAAGAGAGATTTCCCTTGGTTTTATGCCACAAGATTACCACAAAAAACTGCAATTGGATTTATCACCA
ATAGCTTATATCAGCAAAACTGGGGAAAAAGAGGAACTTCAGAAAATCCAATCTCACCTAGCCAGTCTCAATTTCAGTTA
TCCAGAAATGCACCATCAAATTCGCTCCTTATCTGGCGGACAACAGGGAAAACTCCTGCTTTTGGATTTAGTCCTGCGCA
AACCAAACTTTCTCCTGCTGGATGAACCCACACGAAACTTTTCTCCCACTTCTCAACCCCAAATCAGAAAACTCTTTGCA
ACCTATCCAGGCGGTCTCATCACTGTTTCGCATGACCGTCGTTTCTTAAAAGAAATCTGCTCGATCATCTATCGCATGAC
AGAACACGGTTTGAAGCTAGTTAATTTAGAAGATTTATAA

Upstream 100 bases:

>100_bases
CTCTTTTTGTGTGCTCTTTTATGCTCTTTTTCTGGCATGTTAATAGAGTTTTTTTTGACATAGACTTTGGGCTCTACTAG
GTAAAGTAGAGCTTTTTGTT

Downstream 100 bases:

>100_bases
ATTTGCAACATAGCAGATAGGTGGGGCAAAAACACAATTTTAGGAGAAAAAGAAGTAAATCTTCCCATAGTAAAACGCAT
AATATCAAGTTTTCACACCT

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 519; Mature: 519

Protein sequence:

>519_residues
MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLTMTIQDGEKVAIIGEEGNGKSTLLKTLMGEDLSDFTIKGDIQSDYQS
LAYIPQKVPEDLKKKTLHDYFFLDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLVEHLDYDSYSEQRKANFAKQSQQ
AANNQRAYDKTMKKHRRVKQNVETALRATKDSTAGRLLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLP
ASKVLVQLEKENLSIDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHKKLQLDLSP
IAYISKTGEKEELQKIQSHLASLNFSYPEMHHQIRSLSGGQQGKLLLLDLVLRKPNFLLLDEPTRNFSPTSQPQIRKLFA
TYPGGLITVSHDRRFLKEICSIIYRMTEHGLKLVNLEDL

Sequences:

>Translated_519_residues
MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLTMTIQDGEKVAIIGEEGNGKSTLLKTLMGEDLSDFTIKGDIQSDYQS
LAYIPQKVPEDLKKKTLHDYFFLDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLVEHLDYDSYSEQRKANFAKQSQQ
AANNQRAYDKTMKKHRRVKQNVETALRATKDSTAGRLLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLP
ASKVLVQLEKENLSIDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHKKLQLDLSP
IAYISKTGEKEELQKIQSHLASLNFSYPEMHHQIRSLSGGQQGKLLLLDLVLRKPNFLLLDEPTRNFSPTSQPQIRKLFA
TYPGGLITVSHDRRFLKEICSIIYRMTEHGLKLVNLEDL
>Mature_519_residues
MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLTMTIQDGEKVAIIGEEGNGKSTLLKTLMGEDLSDFTIKGDIQSDYQS
LAYIPQKVPEDLKKKTLHDYFFLDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLVEHLDYDSYSEQRKANFAKQSQQ
AANNQRAYDKTMKKHRRVKQNVETALRATKDSTAGRLLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLP
ASKVLVQLEKENLSIDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHKKLQLDLSP
IAYISKTGEKEELQKIQSHLASLNFSYPEMHHQIRSLSGGQQGKLLLLDLVLRKPNFLLLDEPTRNFSPTSQPQIRKLFA
TYPGGLITVSHDRRFLKEICSIIYRMTEHGLKLVNLEDL

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI10947137, Length=514, Percent_Identity=24.3190661478599, Blast_Score=134, Evalue=3e-31,
Organism=Homo sapiens, GI27881506, Length=514, Percent_Identity=24.3190661478599, Blast_Score=134, Evalue=3e-31,
Organism=Homo sapiens, GI148612853, Length=392, Percent_Identity=24.7448979591837, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI69354671, Length=391, Percent_Identity=26.8542199488491, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI10947135, Length=391, Percent_Identity=26.8542199488491, Blast_Score=117, Evalue=3e-26,
Organism=Escherichia coli, GI1789751, Length=532, Percent_Identity=28.5714285714286, Blast_Score=191, Evalue=1e-49,
Organism=Escherichia coli, GI2367384, Length=537, Percent_Identity=28.4916201117318, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1787182, Length=522, Percent_Identity=26.2452107279693, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1787041, Length=546, Percent_Identity=23.992673992674, Blast_Score=134, Evalue=9e-33,
Organism=Caenorhabditis elegans, GI17555318, Length=537, Percent_Identity=24.7672253258845, Blast_Score=151, Evalue=9e-37,
Organism=Caenorhabditis elegans, GI17553372, Length=531, Percent_Identity=25.4237288135593, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17559834, Length=536, Percent_Identity=25, Blast_Score=130, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6321121, Length=550, Percent_Identity=24.7272727272727, Blast_Score=136, Evalue=6e-33,
Organism=Saccharomyces cerevisiae, GI6320874, Length=515, Percent_Identity=24.8543689320388, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6323278, Length=193, Percent_Identity=31.6062176165803, Blast_Score=80, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6324314, Length=193, Percent_Identity=31.6062176165803, Blast_Score=77, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6325030, Length=182, Percent_Identity=29.1208791208791, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24642252, Length=532, Percent_Identity=24.812030075188, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI18859989, Length=532, Percent_Identity=24.812030075188, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24666836, Length=393, Percent_Identity=27.2264631043257, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24641342, Length=538, Percent_Identity=26.5799256505576, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24661270, Length=169, Percent_Identity=28.4023668639053, Blast_Score=66, Evalue=7e-11,
Organism=Drosophila melanogaster, GI21355589, Length=169, Percent_Identity=28.4023668639053, Blast_Score=66, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 59545; Mature: 59545

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLTMTIQDGEKVAIIGEEGNGKSTLLKTL
CCCCCCCCCCEEEEEEEEEEECCCCHHHHHHHHEEEEECCCEEEEEECCCCCHHHHHHHH
MGEDLSDFTIKGDIQSDYQSLAYIPQKVPEDLKKKTLHDYFFLDSIDLDYSILYRLAEEL
HCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHH
HFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLDEPSNDLDLETVDWLKGQIQK
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHH
TRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLVEHLDYDSYSEQRKANFAKQSQQ
CCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
AANNQRAYDKTMKKHRRVKQNVETALRATKDSTAGRLLAKKMKTVLSQEKRYEKAAQSMT
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLSIDDRVLVQKLQLTVRGQEKIGIIGPN
HCCCHHHHHHHHHHHCCCCCHHHHHEEECCCCCCCHHHHHHHHHHHHEECCCEEEEECCC
GVGKSTLLAKLKQLLNDKREISLGFMPQDYHKKLQLDLSPIAYISKTGEKEELQKIQSHL
CCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHEECCCCHHHHHHCCCCHHHHHHHHHHH
ASLNFSYPEMHHQIRSLSGGQQGKLLLLDLVLRKPNFLLLDEPTRNFSPTSQPQIRKLFA
HHCCCCCHHHHHHHHHCCCCCCCCEEHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHH
TYPGGLITVSHDRRFLKEICSIIYRMTEHGLKLVNLEDL
HCCCCEEEECCCHHHHHHHHHHHHHHHHCCEEEEEECCC
>Mature Secondary Structure
MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLTMTIQDGEKVAIIGEEGNGKSTLLKTL
CCCCCCCCCCEEEEEEEEEEECCCCHHHHHHHHEEEEECCCEEEEEECCCCCHHHHHHHH
MGEDLSDFTIKGDIQSDYQSLAYIPQKVPEDLKKKTLHDYFFLDSIDLDYSILYRLAEEL
HCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHH
HFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLDEPSNDLDLETVDWLKGQIQK
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHH
TRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLVEHLDYDSYSEQRKANFAKQSQQ
CCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
AANNQRAYDKTMKKHRRVKQNVETALRATKDSTAGRLLAKKMKTVLSQEKRYEKAAQSMT
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLSIDDRVLVQKLQLTVRGQEKIGIIGPN
HCCCHHHHHHHHHHHCCCCCHHHHHEEECCCCCCCHHHHHHHHHHHHEECCCEEEEECCC
GVGKSTLLAKLKQLLNDKREISLGFMPQDYHKKLQLDLSPIAYISKTGEKEELQKIQSHL
CCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHEECCCCHHHHHHCCCCHHHHHHHHHHH
ASLNFSYPEMHHQIRSLSGGQQGKLLLLDLVLRKPNFLLLDEPTRNFSPTSQPQIRKLFA
HHCCCCCHHHHHHHHHCCCCCCCCEEHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHH
TYPGGLITVSHDRRFLKEICSIIYRMTEHGLKLVNLEDL
HCCCCEEEECCCHHHHHHHHHHHHHHHHCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]