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The map label for this gene is lacA

Identifier: 116515890

GI number: 116515890

Start: 1081765

End: 1082190

Strand: Reverse

Name: lacA

Synonym: SPD_1053

Alternate gene names: 116515890

Gene position: 1082190-1081765 (Counterclockwise)

Preceding gene: 116516900

Following gene: 116517129

Centisome position: 52.89

GC content: 41.31

Gene sequence:

>426_bases
ATGTCTATTGTTATCGGTGCAGATGCTGCAGGTTTGAGATTGAAAGAAGTTGTGAAAGACTTCTTAGAAAAAGAAAACTT
CCACCTTGTGGATGTTACAGCTGAAGGTCAAGACTTTGTTGATGTGACTCTCGCTGTTGCTGCAGAAGTAAACAAAGAAG
AACAAAACCTTGGTATCGTGATTGATGCTTATGGAGCTGGTCCATTTATGGTTGCAACTAAGATCAAAGGAATGGTTGCT
GCAGAAGTATCTGACGAACGTTCAGCTTATATGACTCGTGGCCACAACAACTCACGTATGATCACTATGGGTGCACAACT
TGTTGGTGATGAATTGGCTAAAAACATCGCTAAAGGATTTGTTAACGGTAAATACGATGGTGGACGTCATCAAATCCGGG
TCGACATGTTGAACAAAATGGGCTAA

Upstream 100 bases:

>100_bases
AGTAGTATATTATGTTTGTGAGGACTAATTGACTGTTTTTTAAAGACAGCCAATACACTGCTGGAATCCAGCATAGAAAA
AATAAAAAGGAGTATACAAT

Downstream 100 bases:

>100_bases
TTAGATTACAGTAAGAAAGGTAAGTTAAAAATGAGAATTGCAATTGGATGCGACCACATCGTAACAGATGAAAAAATGGC
GGTTTCAGAATTTTTGAAAT

Product: galactose-6-phosphate isomerase subunit LacA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 141; Mature: 140

Protein sequence:

>141_residues
MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTLAVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVA
AEVSDERSAYMTRGHNNSRMITMGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG

Sequences:

>Translated_141_residues
MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTLAVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVA
AEVSDERSAYMTRGHNNSRMITMGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG
>Mature_140_residues
SIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTLAVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAA
EVSDERSAYMTRGHNNSRMITMGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG

Specific function: In Addition To Its Activity On D-Ribose 5-Phosphate It Probably Also Has Activity On D-Allose 6-Phosphate. [C]

COG id: COG0698

COG function: function code G; Ribose 5-phosphate isomerase RpiB

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lacAB/rpiB family

Homologues:

Organism=Escherichia coli, GI1790528, Length=141, Percent_Identity=31.9148936170213, Blast_Score=73, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LACA_STRP2 (Q04KC1)

Other databases:

- EMBL:   CP000410
- RefSeq:   YP_816527.1
- ProteinModelPortal:   Q04KC1
- SMR:   Q04KC1
- STRING:   Q04KC1
- EnsemblBacteria:   EBSTRT00000018991
- GeneID:   4441388
- GenomeReviews:   CP000410_GR
- KEGG:   spd:SPD_1053
- eggNOG:   COG0698
- GeneTree:   EBGT00050000027285
- HOGENOM:   HBG636953
- OMA:   ARMITVG
- ProtClustDB:   PRK08621
- HAMAP:   MF_01555
- InterPro:   IPR004783
- InterPro:   IPR003500
- Gene3D:   G3DSA:3.40.1400.10
- PIRSF:   PIRSF005384
- TIGRFAMs:   TIGR01118
- TIGRFAMs:   TIGR00689

Pfam domain/function: PF02502 LacAB_rpiB; SSF89623 Rib/Gal_isomrase

EC number: =5.3.1.26

Molecular weight: Translated: 15245; Mature: 15114

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTLAVAAEVNKEEQNLGIV
CEEEEECCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCHHHHEEEEEECCCCCCCCCCEE
IDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMITMGAQLVGDELAKNIAKGF
EECCCCCCEEEEEHHCCEEEEECCCCCHHHEECCCCCCEEEEECHHHHHHHHHHHHHHHC
VNGKYDGGRHQIRVDMLNKMG
CCCCCCCCCEEEEEEECCCCC
>Mature Secondary Structure 
SIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTLAVAAEVNKEEQNLGIV
EEEEECCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCHHHHEEEEEECCCCCCCCCCEE
IDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMITMGAQLVGDELAKNIAKGF
EECCCCCCEEEEEHHCCEEEEECCCCCHHHEECCCCCCEEEEECHHHHHHHHHHHHHHHC
VNGKYDGGRHQIRVDMLNKMG
CCCCCCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA