Click here to switch to the map view.

The map label for this gene is aroD

Identifier: 116517065

GI number: 116517065

Start: 1239808

End: 1240485

Strand: Reverse

Name: aroD

Synonym: SPD_1211

Alternate gene names: 116517065

Gene position: 1240485-1239808 (Counterclockwise)

Preceding gene: 116516182

Following gene: 116516036

Centisome position: 60.63

GC content: 44.1

Gene sequence:

>678_bases
ATGAAATTAATCGTTTCAGTAATGCCAAGAAGTTTAGAGGAGGCTCAGGCTCTGGATGCCACGAGGTACCTGGATGCCGA
CATCATTGAATGGCGTGCCGACTATCTGCCTAAAGAAGCGATTTTGCAGGTAGCTCCAGCCATTTTTGAAAAATTCGCAG
GCCGTGAGTTGGTTTTCACGCTACGAACTCGCTCCGAAGGTGGAGAAATCGACCTTTCTCCAGAAGAGTATATCCATCTA
ATCAAGGAAGTTGCGCAACTCTATCAACCAGACTATATTGATTTTGAGTACTATAGCTACAAGGATGTTTTTGAGGAAAT
GCTGGACTTCCCAAATCTTGTTTTGAGTTACCATAATTTCCAAGAAACACCTGAGAACATGATGGAAATCTTGTCAGAGT
TGACGATCCTAAATCCAAAACTTGTTAAGGTTGCGGTGATGGCTCACACGGAGCAGGATGTCTTAGACTTGATGAACTAT
ACACGAGGCTTTAAAACCCTCAATCCTGAACAGGAATATGTGACCATTTCTATGGGTAAGGTGGGCAAGGTCTCTCGTAT
CACTGCGGATGTGACTGGTTCGAGTTGGTCTTTTGCCAGTCTGGATGAGGTTAGTGCCCCTGGGCAGATTTCTCTAGCTA
GCATGAAAAAAATCAGGGAGATTTTGGATGAAGCTTGA

Upstream 100 bases:

>100_bases
ACCAGATTTTAAACAAATATGGTCTTCCAGCAGATTTTGCCTATAATAAAAAAGATGAAAGTAGTAATTACCTCAAGGTG
ATTAGTATGAAGGTTAGTAA

Downstream 100 bases:

>100_bases
TGGCTATACACGTTTAGCTGCAGTTGTTGCCAATCCTATTAAGCATTCTATTTCTCCCTTCATCCACAATAGAGCCTTTG
AGGCGACAGCTACCAACGGT

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type I DHQase

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQVAPAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHL
IKEVAQLYQPDYIDFEYYSYKDVFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKIREILDEA

Sequences:

>Translated_225_residues
MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQVAPAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHL
IKEVAQLYQPDYIDFEYYSYKDVFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKIREILDEA
>Mature_225_residues
MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQVAPAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHL
IKEVAQLYQPDYIDFEYYSYKDVFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKIREILDEA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; third step. [C]

COG id: COG0710

COG function: function code E; 3-dehydroquinate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I 3-dehydroquinase family

Homologues:

Organism=Escherichia coli, GI1787984, Length=237, Percent_Identity=31.6455696202532, Blast_Score=118, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROD_STRP2 (Q04JX0)

Other databases:

- EMBL:   CP000410
- RefSeq:   YP_816678.1
- ProteinModelPortal:   Q04JX0
- SMR:   Q04JX0
- STRING:   Q04JX0
- EnsemblBacteria:   EBSTRT00000019416
- GeneID:   4441953
- GenomeReviews:   CP000410_GR
- KEGG:   spd:SPD_1211
- eggNOG:   COG0710
- GeneTree:   EBGT00050000027890
- HOGENOM:   HBG732926
- OMA:   IAKLAVM
- ProtClustDB:   PRK02412
- HAMAP:   MF_00214
- InterPro:   IPR013785
- InterPro:   IPR001381
- Gene3D:   G3DSA:3.20.20.70
- TIGRFAMs:   TIGR01093

Pfam domain/function: PF01487 DHquinase_I

EC number: =4.2.1.10

Molecular weight: Translated: 25720; Mature: 25720

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: PS01028 DEHYDROQUINASE_I

Important sites: ACT_SITE 118-118 ACT_SITE 143-143

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQVAPAIFEKFAGRELVFT
CCEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEE
LRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKDVFEEMLDFPNLVLSYHNF
EEECCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCHHCCHHHHHHHHHCCHHHHHHHHCH
QETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNYTRGFKTLNPEQEYVTISMGK
HCCHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCC
VGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKIREILDEA
CCCHHEEEEECCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQVAPAIFEKFAGRELVFT
CCEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEE
LRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKDVFEEMLDFPNLVLSYHNF
EEECCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCHHCCHHHHHHHHHCCHHHHHHHHCH
QETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNYTRGFKTLNPEQEYVTISMGK
HCCHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCC
VGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKIREILDEA
CCCHHEEEEECCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA