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The map label for this gene is coaE [H]

Identifier: 116516997

GI number: 116516997

Start: 873149

End: 873754

Strand: Direct

Name: coaE [H]

Synonym: SPD_0859

Alternate gene names: 116516997

Gene position: 873149-873754 (Clockwise)

Preceding gene: 116515925

Following gene: 116516183

Centisome position: 42.67

GC content: 44.72

Gene sequence:

>606_bases
ATGGGAAAAATCATCGGAATCACTGGGGGAATTGCCTCAGGTAAGTCAACTGTGACAAATTTTCTAAGACAGCAAGGCTT
TCAAGCAGTGGATGCCGACGCAGTCGTCCACCAACTACAGAAACCTGGTGGTCGTCTGTTTGAGGCTCTAGTACAGCACT
TTGGGCAAGAAATCATTCTTGAAAACGGAGAACTCAATCGCCCTCTCCTAGCTAGTCTCATCTTTTCAAATCCTGAAGAG
CAAAAATGGTCTAATCAAATTCAAGGGGAGATTATCCGTGAGGAACTGGCTACTTTGAGAGAACAGTTGGCTCAGACAGA
AGAGATTTTCTTCATGGATATTCCCCTACTTTTTGAGCAGGACTACAGCGATTGGTTTGCTGAGACTTGGTTGGTCTATG
TGGACCGAGATGCCCAAGTAGAACGCTTAATGAAAAGGGACCAGTTGTCCAAAGATGAAGCTGAGTCTCGTCTGGCAGCC
CAGTGGCCTTTAGAAAAAAAGAAAGATTTGGCCAGCCAGGTTCTTGATAATAATGGCAATCAGAACCAGCTTCTTAATCA
AGTGCATATCCTTCTTGAGGGAGGTAGGCAAGATGACAGAGATTAA

Upstream 100 bases:

>100_bases
AGACTGGTCAAGAATGTGTACGCTGTGGTACCATCATTGAGAAAATTCAACTAGGCGGACGTGGAACCCACTTTTGTCCA
AACTGTCAAAGGAGGGACTG

Downstream 100 bases:

>100_bases
CTGGAAGGATAATCTGCGTATTGCCTGGTTTGGTAATTTTCTGACAGGAGCCAGTATTTCTTTGGTTGTACCTTTTATGC
CCATCTTCGTGGAAAATCTA

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MGKIIGITGGIASGKSTVTNFLRQQGFQAVDADAVVHQLQKPGGRLFEALVQHFGQEIILENGELNRPLLASLIFSNPEE
QKWSNQIQGEIIREELATLREQLAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD

Sequences:

>Translated_201_residues
MGKIIGITGGIASGKSTVTNFLRQQGFQAVDADAVVHQLQKPGGRLFEALVQHFGQEIILENGELNRPLLASLIFSNPEE
QKWSNQIQGEIIREELATLREQLAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD
>Mature_200_residues
GKIIGITGGIASGKSTVTNFLRQQGFQAVDADAVVHQLQKPGGRLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQ
KWSNQIQGEIIREELATLREQLAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAAQ
WPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=191, Percent_Identity=39.2670157068063, Blast_Score=139, Evalue=1e-33,
Organism=Homo sapiens, GI191252795, Length=191, Percent_Identity=39.2670157068063, Blast_Score=139, Evalue=1e-33,
Organism=Homo sapiens, GI110227607, Length=162, Percent_Identity=31.4814814814815, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI110227605, Length=162, Percent_Identity=31.4814814814815, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI110227603, Length=162, Percent_Identity=31.4814814814815, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI110227601, Length=162, Percent_Identity=31.4814814814815, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI205277394, Length=162, Percent_Identity=31.4814814814815, Blast_Score=88, Evalue=6e-18,
Organism=Escherichia coli, GI1786292, Length=188, Percent_Identity=34.0425531914894, Blast_Score=112, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17554944, Length=193, Percent_Identity=40.9326424870466, Blast_Score=137, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI25143409, Length=159, Percent_Identity=28.9308176100629, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320402, Length=193, Percent_Identity=33.6787564766839, Blast_Score=98, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24644728, Length=179, Percent_Identity=35.195530726257, Blast_Score=116, Evalue=9e-27,
Organism=Drosophila melanogaster, GI24658602, Length=164, Percent_Identity=35.9756097560976, Blast_Score=104, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22948; Mature: 22817

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKIIGITGGIASGKSTVTNFLRQQGFQAVDADAVVHQLQKPGGRLFEALVQHFGQEIIL
CCCEEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCHHHHH
ENGELNRPLLASLIFSNPEEQKWSNQIQGEIIREELATLREQLAQTEEIFFMDIPLLFEQ
CCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHC
DYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAAQWPLEKKKDLASQVLDNNGN
CHHHHHHHHHHHEECCCHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
QNQLLNQVHILLEGGRQDDRD
HHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
GKIIGITGGIASGKSTVTNFLRQQGFQAVDADAVVHQLQKPGGRLFEALVQHFGQEIIL
CCEEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCHHHHH
ENGELNRPLLASLIFSNPEEQKWSNQIQGEIIREELATLREQLAQTEEIFFMDIPLLFEQ
CCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHC
DYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAAQWPLEKKKDLASQVLDNNGN
CHHHHHHHHHHHEECCCHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
QNQLLNQVHILLEGGRQDDRD
HHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11463916 [H]