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The map label for this gene is cad [H]

Identifier: 116516967

GI number: 116516967

Start: 826193

End: 827668

Strand: Direct

Name: cad [H]

Synonym: SPD_0809

Alternate gene names: 116516967

Gene position: 826193-827668 (Clockwise)

Preceding gene: 116516245

Following gene: 116515725

Centisome position: 40.38

GC content: 43.83

Gene sequence:

>1476_bases
TTGAAAGAGTTAGATCAAAACCAAGCCCCAATTTATGAGTCCTTGGTGAAGTTACGCAAGAAAAGGATTGTTCCCTTTGA
TGTTCCAGGTCACAAGCGTGGACGGGGAAATCCAGAACTTGTCGAACTCTTAGGAGAAAAATGTGTAGGCATTGATGTCA
ATTCGATGAAACCCTTGGATAATTTAGGCCATCCTATTTCGATTATTCGTGATGCAGAGGAGCTGGCTGCAGATGCTTTT
GGAGCTAGCCATGCCTTTCTAATGATTGGTGGAACAACTTCATCGGTGCAGACTATGATTCTGGCAACCTGCAAGGCAGG
AGATAAGATTATTCTGCCACGAAATGTCCATAAATCTGCTATCAATGCGTTGGTTCTATGTGGTGCCATTCCCATCTATA
TCGAGATGAGTGTAGATCCTAAGATTGGTATCGCTTTAGGTCTTGAAAATGACCGAGTAGCACAGGCCATAAAGGACCAT
CCAGATGCTAAGGCTATCCTAATCAACAATCCTACTTACTACGGCATATGTTCAGACCTAAAGGGGTTGACAGAAATGGC
TCATGAAGCTGGCATGATGGTTTTAGTAGATGAAGCCCATGGAGCGCATTTGCATTTCACTGGTAAACTTCCAATTTCTG
CTATGGATGCAGGAGCTGATATGGCAGCAGTTTCCATGCATAAGTCTGGTGGGAGTTTGACACAAAGTTCGCTTCTTTTA
ATCGGGGAGCAGATGAATCCCGAGTACGTTCGTCAGATTATAAACCTGACACAGTCTACATCTGCCTCTTACTTATTGAT
GGCTAGTTTGGATATTTCACGTCGCAACTTGGCCCTTCGTGGTAAAGAGTCGTTTGAGGAAGTCATTGAGCTATCCGAGT
ACGCTCGTCATGAAATCAATGCCATTGGCGGTTACTATGCTTACTCAAAAGAGTTAATAGATGGTGTGTCGGTCTGTGAT
TTTGATGTAACCAAGTTGTCAGTTTACACTCAGGGAATAGGCTTAACAGGTATCGAGGTTTATGACCTCTTGCGAGACGA
ATACGACATTCAGATCGAGTTTGGTGATATCGGCAATATCTTGGCCTATATTTCCATCGGCGACCGCATCCAAGACATCG
AGCGCTTGGTTGGTGCTCTGGCTGATATTAAGAGACTCTATTCACGAGATGGGAAGGACTTAATAGCTGGAGAATATATT
CAGCCCGAGTTGGTGCTGTCTCCACAAGAAGCCTTCTATTCAGAGAGAAAAAGTTTGACCTTAGATGAGTCTGTTGGACA
GGTCTGTGGAGAATTTGTCATGTGCTATCCTCCAGGGATTCCTATCTTGGCTCCTGGTGAACGCATTACACGAGAAATTG
TAGACTATATCCAATTCGCCAAGGAACGTGGTTGCTCCCTCCAAGGGACGGAAGATCCAGAGGTCAATCATATCAACGTT
ATTAAGAGAAAGACAAACTATAAGAAAAGTCAATAG

Upstream 100 bases:

>100_bases
AGAAGATTGCAGAGCAGGTGAAAACCTGCTCTTTTTTCATGAGTCAACCTTTAGTTCCTTAGTTTTCATAAGGTCCTAAA
AATATTGAAAGGAGTATGTT

Downstream 100 bases:

>100_bases
TTTTATCTAAACTATTTCTTATTTCAATTTGATGATTTGGCGATGATTTTAGAGCACGGCAAAAAGCCCTTGAATTAGAA
GCGGTCAATCGCTTAATTTC

Product: lysine decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 491

Protein sequence:

>491_residues
MKELDQNQAPIYESLVKLRKKRIVPFDVPGHKRGRGNPELVELLGEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAF
GASHAFLMIGGTTSSVQTMILATCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAGADMAAVSMHKSGGSLTQSSLLL
IGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRNLALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCD
FDVTKLSVYTQGIGLTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGKDLIAGEYI
QPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERITREIVDYIQFAKERGCSLQGTEDPEVNHINV
IKRKTNYKKSQ

Sequences:

>Translated_491_residues
MKELDQNQAPIYESLVKLRKKRIVPFDVPGHKRGRGNPELVELLGEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAF
GASHAFLMIGGTTSSVQTMILATCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAGADMAAVSMHKSGGSLTQSSLLL
IGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRNLALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCD
FDVTKLSVYTQGIGLTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGKDLIAGEYI
QPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERITREIVDYIQFAKERGCSLQGTEDPEVNHINV
IKRKTNYKKSQ
>Mature_491_residues
MKELDQNQAPIYESLVKLRKKRIVPFDVPGHKRGRGNPELVELLGEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAF
GASHAFLMIGGTTSSVQTMILATCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAGADMAAVSMHKSGGSLTQSSLLL
IGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRNLALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCD
FDVTKLSVYTQGIGLTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGKDLIAGEYI
QPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERITREIVDYIQFAKERGCSLQGTEDPEVNHINV
IKRKTNYKKSQ

Specific function: Catalyzes the formation of agmatine from arginine [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1786384, Length=558, Percent_Identity=22.7598566308244, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI221142684, Length=352, Percent_Identity=24.1477272727273, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI87082193, Length=378, Percent_Identity=24.3386243386243, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 53903; Mature: 53903

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKELDQNQAPIYESLVKLRKKRIVPFDVPGHKRGRGNPELVELLGEKCVGIDVNSMKPLD
CCCCCCCCCHHHHHHHHHHHHCCCEECCCCCCCCCCCHHHHHHHCCCEECCCCCCCCCHH
NLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILATCKAGDKIILPRNVHKSA
HCCCCHHHHHCHHHHHHHHCCCCCEEEEECCCCHHHHHHHHEEECCCCEEEECCCHHHHH
INALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDHPDAKAILINNPTYYGICSDL
HHHHHHHCCCEEEEEEECCCCEEEEEECCCHHHHHHHHCCCCCCEEEECCCEEEEHHHHH
KGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAGADMAAVSMHKSGGSLTQSSLLL
HHHHHHHHHCCEEEEEECCCCCEEEEECCCCCEECCCCCCEEEEEEECCCCCCCCCEEEE
IGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRNLALRGKESFEEVIELSEYARHEIN
EECCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEECCHHHHHHHHHHHHHHHHHHH
AIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIGLTGIEVYDLLRDEYDIQIEFGDIGNI
HCCCHHHHHHHHHCCCEECCCCCEEEEEEECCCCCCHHHHHHHHCCCEEEEEEECCCCCE
LAYISIGDRIQDIERLVGALADIKRLYSRDGKDLIAGEYIQPELVLSPQEAFYSERKSLT
EEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCEEECCHHHHHHHHCCCC
LDESVGQVCGEFVMCYPPGIPILAPGERITREIVDYIQFAKERGCSLQGTEDPEVNHINV
HHHHHHHHHHCEEEECCCCCCEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEE
IKRKTNYKKSQ
EEECCCCCCCC
>Mature Secondary Structure
MKELDQNQAPIYESLVKLRKKRIVPFDVPGHKRGRGNPELVELLGEKCVGIDVNSMKPLD
CCCCCCCCCHHHHHHHHHHHHCCCEECCCCCCCCCCCHHHHHHHCCCEECCCCCCCCCHH
NLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILATCKAGDKIILPRNVHKSA
HCCCCHHHHHCHHHHHHHHCCCCCEEEEECCCCHHHHHHHHEEECCCCEEEECCCHHHHH
INALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDHPDAKAILINNPTYYGICSDL
HHHHHHHCCCEEEEEEECCCCEEEEEECCCHHHHHHHHCCCCCCEEEECCCEEEEHHHHH
KGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAGADMAAVSMHKSGGSLTQSSLLL
HHHHHHHHHCCEEEEEECCCCCEEEEECCCCCEECCCCCCEEEEEEECCCCCCCCCEEEE
IGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRNLALRGKESFEEVIELSEYARHEIN
EECCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEECCHHHHHHHHHHHHHHHHHHH
AIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIGLTGIEVYDLLRDEYDIQIEFGDIGNI
HCCCHHHHHHHHHCCCEECCCCCEEEEEEECCCCCCHHHHHHHHCCCEEEEEEECCCCCE
LAYISIGDRIQDIERLVGALADIKRLYSRDGKDLIAGEYIQPELVLSPQEAFYSERKSLT
EEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCEEECCHHHHHHHHCCCC
LDESVGQVCGEFVMCYPPGIPILAPGERITREIVDYIQFAKERGCSLQGTEDPEVNHINV
HHHHHHHHHHCEEEECCCCCCEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEE
IKRKTNYKKSQ
EEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]