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The map label for this gene is appB [H]

Identifier: 116516656

GI number: 116516656

Start: 1197309

End: 1198259

Strand: Reverse

Name: appB [H]

Synonym: SPD_1169

Alternate gene names: 116516656

Gene position: 1198259-1197309 (Counterclockwise)

Preceding gene: 116515339

Following gene: 116515771

Centisome position: 58.56

GC content: 32.91

Gene sequence:

>951_bases
ATGAAAAAATATATTCTAAAAAAAGTATTATTCATGATTCCTATGTTGTTGATTATTAGCTTTTTAGTATTCATTGCACT
AGATTTAACACCAGCAGATCCATTGACATATATGGTATCTCCAGATATGGCTAGTAGTGCAGAACAAATCGAAAAGCTAA
GACAGCAATTAGGTTTAAATGATCCAGTATTAGTTCGCTATGGAAGATGGCTTTGGCAATTACTCCATGGTGATTTTGGA
TACAGTATTGTAAATGGTAACCCAATTTCCAAAATTGTAGGACAAGCATTGCCTGCAACTTTTGAATTAGCTTTTGTGTC
ATTAATTATTTCAACAATTGTTGGTATTGTAATTGGGGTTATATCAGCCGTTAAACAAAATGGTATTATCGATAATGTTG
CTCGTTTTCTAGCTGTTATCGGAACTGCGATTCCACAATTTTTCTTTGGTATTTTAATTTTAAACTTCTTTGCAATTCAG
TTAAGAATTTTACCTATTGGTGGTAGATTTGCCAGTGGAGATTTTACATTTATTAATAGAGTTGAACACTTAATTCTACC
AGTAATGGCTATGTCAATTGCATTGGTAGCTGCTTTAATGAGATACACACGTAATTCTATGTTGGATGTTTTTAATGCAG
ATTATGTTAAAACAGCTCGTGCAAAAGGTGTTCCTGAATGGAAAGTTTATTTTAAACACATATTTAGAAATGCTATGCGA
CCAATTTTAGTGTTATTGATTTTCCGTCTACCAATGTTAATTGGTGGATCAGTAATTATCGAGAGTGTCTTTTCTTGGCC
TGGAATTGGTTCTATCATCCTATCTAGTGTAACAGCAGGTGACTATCCTGTAATTATGATTACCACATTAATGATTTCTG
TCGTAGTGTTATTTGCTAGTCTACTTGTAGATATTATGGCTGCAATATTAGACCCACGTATTCGTTATTAG

Upstream 100 bases:

>100_bases
AAATTATCAGTGATTAAGTTTGATAATCTTTTAGGAGTGTAGAGATGCTGGTTTATTGAATCATGTATCTCTCACTCTTG
TTTTTTCAGGAGAAATTAAA

Downstream 100 bases:

>100_bases
GAAGGAGGTCAATGTTATGAAACCTATGCCTTTATGGAAAAGAAATTTGAAAAAATTCTATAATAACAAATTGGCCTTTA
TCGGCTTTATATGCTTCATG

Product: oligopeptide ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MKKYILKKVLFMIPMLLIISFLVFIALDLTPADPLTYMVSPDMASSAEQIEKLRQQLGLNDPVLVRYGRWLWQLLHGDFG
YSIVNGNPISKIVGQALPATFELAFVSLIISTIVGIVIGVISAVKQNGIIDNVARFLAVIGTAIPQFFFGILILNFFAIQ
LRILPIGGRFASGDFTFINRVEHLILPVMAMSIALVAALMRYTRNSMLDVFNADYVKTARAKGVPEWKVYFKHIFRNAMR
PILVLLIFRLPMLIGGSVIIESVFSWPGIGSIILSSVTAGDYPVIMITTLMISVVVLFASLLVDIMAAILDPRIRY

Sequences:

>Translated_316_residues
MKKYILKKVLFMIPMLLIISFLVFIALDLTPADPLTYMVSPDMASSAEQIEKLRQQLGLNDPVLVRYGRWLWQLLHGDFG
YSIVNGNPISKIVGQALPATFELAFVSLIISTIVGIVIGVISAVKQNGIIDNVARFLAVIGTAIPQFFFGILILNFFAIQ
LRILPIGGRFASGDFTFINRVEHLILPVMAMSIALVAALMRYTRNSMLDVFNADYVKTARAKGVPEWKVYFKHIFRNAMR
PILVLLIFRLPMLIGGSVIIESVFSWPGIGSIILSSVTAGDYPVIMITTLMISVVVLFASLLVDIMAAILDPRIRY
>Mature_316_residues
MKKYILKKVLFMIPMLLIISFLVFIALDLTPADPLTYMVSPDMASSAEQIEKLRQQLGLNDPVLVRYGRWLWQLLHGDFG
YSIVNGNPISKIVGQALPATFELAFVSLIISTIVGIVIGVISAVKQNGIIDNVARFLAVIGTAIPQFFFGILILNFFAIQ
LRILPIGGRFASGDFTFINRVEHLILPVMAMSIALVAALMRYTRNSMLDVFNADYVKTARAKGVPEWKVYFKHIFRNAMR
PILVLLIFRLPMLIGGSVIIESVFSWPGIGSIILSSVTAGDYPVIMITTLMISVVVLFASLLVDIMAAILDPRIRY

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=316, Percent_Identity=36.0759493670886, Blast_Score=217, Evalue=7e-58,
Organism=Escherichia coli, GI1789965, Length=338, Percent_Identity=31.3609467455621, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI1789888, Length=316, Percent_Identity=36.0759493670886, Blast_Score=205, Evalue=3e-54,
Organism=Escherichia coli, GI1787497, Length=317, Percent_Identity=32.4921135646688, Blast_Score=181, Evalue=4e-47,
Organism=Escherichia coli, GI1787761, Length=317, Percent_Identity=34.0694006309148, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI1787550, Length=265, Percent_Identity=29.0566037735849, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1788504, Length=281, Percent_Identity=33.4519572953737, Blast_Score=137, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35111; Mature: 35111

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKYILKKVLFMIPMLLIISFLVFIALDLTPADPLTYMVSPDMASSAEQIEKLRQQLGLN
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCC
DPVLVRYGRWLWQLLHGDFGYSIVNGNPISKIVGQALPATFELAFVSLIISTIVGIVIGV
CCHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
ISAVKQNGIIDNVARFLAVIGTAIPQFFFGILILNFFAIQLRILPIGGRFASGDFTFINR
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCEECCCCHHHHHH
VEHLILPVMAMSIALVAALMRYTRNSMLDVFNADYVKTARAKGVPEWKVYFKHIFRNAMR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
PILVLLIFRLPMLIGGSVIIESVFSWPGIGSIILSSVTAGDYPVIMITTLMISVVVLFAS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
LLVDIMAAILDPRIRY
HHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKKYILKKVLFMIPMLLIISFLVFIALDLTPADPLTYMVSPDMASSAEQIEKLRQQLGLN
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCC
DPVLVRYGRWLWQLLHGDFGYSIVNGNPISKIVGQALPATFELAFVSLIISTIVGIVIGV
CCHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
ISAVKQNGIIDNVARFLAVIGTAIPQFFFGILILNFFAIQLRILPIGGRFASGDFTFINR
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCEECCCCHHHHHH
VEHLILPVMAMSIALVAALMRYTRNSMLDVFNADYVKTARAKGVPEWKVYFKHIFRNAMR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
PILVLLIFRLPMLIGGSVIIESVFSWPGIGSIILSSVTAGDYPVIMITTLMISVVVLFAS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
LLVDIMAAILDPRIRY
HHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]