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The map label for this gene is appC [H]

Identifier: 116515771

GI number: 116515771

Start: 1196441

End: 1197292

Strand: Reverse

Name: appC [H]

Synonym: SPD_1168

Alternate gene names: 116515771

Gene position: 1197292-1196441 (Counterclockwise)

Preceding gene: 116516656

Following gene: 116515706

Centisome position: 58.52

GC content: 36.62

Gene sequence:

>852_bases
ATGAAACCTATGCCTTTATGGAAAAGAAATTTGAAAAAATTCTATAATAACAAATTGGCCTTTATCGGCTTTATATGCTT
CATGCTAATTCTATTAGCATGTATTCTAGCACCTTTATTGACAACCTATTCTCCAGATGTTGTTGATTTAGGATCTATGA
ACCGTCCTCCTTCAGCAAAACACATTCTGGGAACAGATAAACTAGGTCGTGACGTATTTGCTCGAATCCTATATGGTGGT
CGAGTTTCAATTCAAGTCGGGATGTATGGAGCGATTTGTGGAGCGGTTATTGGTACTGTACTTGGTGGTATTGCTGGATA
TTTTGGTGGGAAAATTGATGCTCTTCTAGTTCGTCTAGCAGAATTATTCTTAACATTCCCGAATATGATTGTCATTCTCT
TGCTTTCAAGTATTTTTGGACAAGGTGTATTCAATCTTATCTTCGTATTCTCAGTAATGGGTTGGATGACAACGTTCCGA
ATGGTTCGTAATGAGTTCATGTCTTTGAAACAAGAAACATATGTGGATGTATGTAGAGCTTTTGGTTTTTCTGACAGTCG
AATTATCTTTAATAATATTTTAAGAAATGCTATCTCACCAGTAATTGTATCGTTGTCTTTAAACGTTGCTGGTTTCATTC
TCAGTGAGGCAGGTCTTAGTTTCTTAGGAGTAGGTGTTCCTTCTGATATTCCTACTTGGGGAAATATCATAAATGCTGCC
AAAACAGCCGATGTTATTAAAAATAGTTGGTGGCTGTGGTTAGTTCCAGGGTCAATCATTACTCTTTTCGTTCTTTCTAT
CAACTTTATTGGTGATGGATTACGAGATATAATGGATCCGAAACAACAGTAG

Upstream 100 bases:

>100_bases
TTAATGATTTCTGTCGTAGTGTTATTTGCTAGTCTACTTGTAGATATTATGGCTGCAATATTAGACCCACGTATTCGTTA
TTAGGAAGGAGGTCAATGTT

Downstream 100 bases:

>100_bases
GAGGTTGACAAAATGAATCAAACAGTTTTAGATGTAAAAAACTTAAAAACTGAATTCATCACTGATAAAAAAGCATTTCC
GATTATTAAAGATGTAAACT

Product: oligopeptide ABC transporter pemease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MKPMPLWKRNLKKFYNNKLAFIGFICFMLILLACILAPLLTTYSPDVVDLGSMNRPPSAKHILGTDKLGRDVFARILYGG
RVSIQVGMYGAICGAVIGTVLGGIAGYFGGKIDALLVRLAELFLTFPNMIVILLLSSIFGQGVFNLIFVFSVMGWMTTFR
MVRNEFMSLKQETYVDVCRAFGFSDSRIIFNNILRNAISPVIVSLSLNVAGFILSEAGLSFLGVGVPSDIPTWGNIINAA
KTADVIKNSWWLWLVPGSIITLFVLSINFIGDGLRDIMDPKQQ

Sequences:

>Translated_283_residues
MKPMPLWKRNLKKFYNNKLAFIGFICFMLILLACILAPLLTTYSPDVVDLGSMNRPPSAKHILGTDKLGRDVFARILYGG
RVSIQVGMYGAICGAVIGTVLGGIAGYFGGKIDALLVRLAELFLTFPNMIVILLLSSIFGQGVFNLIFVFSVMGWMTTFR
MVRNEFMSLKQETYVDVCRAFGFSDSRIIFNNILRNAISPVIVSLSLNVAGFILSEAGLSFLGVGVPSDIPTWGNIINAA
KTADVIKNSWWLWLVPGSIITLFVLSINFIGDGLRDIMDPKQQ
>Mature_283_residues
MKPMPLWKRNLKKFYNNKLAFIGFICFMLILLACILAPLLTTYSPDVVDLGSMNRPPSAKHILGTDKLGRDVFARILYGG
RVSIQVGMYGAICGAVIGTVLGGIAGYFGGKIDALLVRLAELFLTFPNMIVILLLSSIFGQGVFNLIFVFSVMGWMTTFR
MVRNEFMSLKQETYVDVCRAFGFSDSRIIFNNILRNAISPVIVSLSLNVAGFILSEAGLSFLGVGVPSDIPTWGNIINAA
KTADVIKNSWWLWLVPGSIITLFVLSINFIGDGLRDIMDPKQQ

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787760, Length=265, Percent_Identity=33.5849056603774, Blast_Score=178, Evalue=3e-46,
Organism=Escherichia coli, GI1787054, Length=276, Percent_Identity=32.6086956521739, Blast_Score=176, Evalue=1e-45,
Organism=Escherichia coli, GI1787498, Length=280, Percent_Identity=36.0714285714286, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI1789889, Length=239, Percent_Identity=34.7280334728033, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI1789964, Length=285, Percent_Identity=33.6842105263158, Blast_Score=140, Evalue=7e-35,
Organism=Escherichia coli, GI1788505, Length=227, Percent_Identity=33.0396475770925, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1787549, Length=284, Percent_Identity=26.7605633802817, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31177; Mature: 31177

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPMPLWKRNLKKFYNNKLAFIGFICFMLILLACILAPLLTTYSPDVVDLGSMNRPPSAK
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCC
HILGTDKLGRDVFARILYGGRVSIQVGMYGAICGAVIGTVLGGIAGYFGGKIDALLVRLA
HHCCCHHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
ELFLTFPNMIVILLLSSIFGQGVFNLIFVFSVMGWMTTFRMVRNEFMSLKQETYVDVCRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGFSDSRIIFNNILRNAISPVIVSLSLNVAGFILSEAGLSFLGVGVPSDIPTWGNIINAA
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEECCCCCCCCCHHHHHHHH
KTADVIKNSWWLWLVPGSIITLFVLSINFIGDGLRDIMDPKQQ
HHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKPMPLWKRNLKKFYNNKLAFIGFICFMLILLACILAPLLTTYSPDVVDLGSMNRPPSAK
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCC
HILGTDKLGRDVFARILYGGRVSIQVGMYGAICGAVIGTVLGGIAGYFGGKIDALLVRLA
HHCCCHHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
ELFLTFPNMIVILLLSSIFGQGVFNLIFVFSVMGWMTTFRMVRNEFMSLKQETYVDVCRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGFSDSRIIFNNILRNAISPVIVSLSLNVAGFILSEAGLSFLGVGVPSDIPTWGNIINAA
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEECCCCCCCCCHHHHHHHH
KTADVIKNSWWLWLVPGSIITLFVLSINFIGDGLRDIMDPKQQ
HHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]