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The map label for this gene is yabD [H]

Identifier: 116516605

GI number: 116516605

Start: 1783593

End: 1784366

Strand: Reverse

Name: yabD [H]

Synonym: SPD_1788

Alternate gene names: 116516605

Gene position: 1784366-1783593 (Counterclockwise)

Preceding gene: 116516291

Following gene: 116515737

Centisome position: 87.21

GC content: 45.48

Gene sequence:

>774_bases
ATGATTTTTGATACACATACACACTTGAATGTAGAAGAATTTGCAGGTCGTGAGGCAGAAGAAATTGCCTTGGCTGCTGA
GATGGGTGTGACACAGATGAATATTGTTGGTTTTGATAAACCGACGATTGAGCATGCCTTGGAGTTGGTAGATGAGTATG
AGCAGCTCTATGCGACTATTGGTTGGCATCCTACAGAAGCTGGTACTTATACAGAGGAAGTTGAGGCTTACTTGTTGGAT
AAGTTAAAACATTCCAAGGTTGTGGCTTTAGGTGAAATTGGCTTAGACTACCATTGGATGACAGCGCCCAAAGAGGTGCA
GGAGCAGGTTTTTCGCCGTCAGATTCAGCTATCTAAGGACTTGGATTTGCCTTTTGTTGTCCATACCCGTGATGCGCTGG
AAGATACCTATGAGATTATCAAGAGTGAGGGCGTTGGTCCTCGTGGTGGTATCATGCATTCATTTTCAGGGACGCTTGAG
TGGGCAGAGAAGTTTGTGGATCTTGGTATGACCATTTCCTTCTCAGGAGTGGTGACCTTCAAGAAGGCAACTGACCTCCA
AGAAGCAGCTAAAGAGTTACCTTTGGACAAGATGTTGGTAGAAACAGATGCGCCTTACTTAGCACCTGTACCCAAGCGTG
GTCGTGAAAATAAAACAGCCTATACTCGCTATGTGGTCGACTTTATCGCTGACTTGCGTGGTATGACGACAGAAGAGCTG
GCGGTAGCAACGACTGCAAATGCAGAACGCATTTTTGGATTGGACAGCAAGTAA

Upstream 100 bases:

>100_bases
CAGAATAGCTCTCTATTGAAGAGAGGAGGGGAAACCGAAAAATTAGGTGCCCCTCCTCTTTTTTGGTATAATAGAAGGAT
AGAAAACGAGGTTAGAAGAG

Downstream 100 bases:

>100_bases
TGAAAGAGAGAATTTCCCAAGTTATCGTGGTTGAAGGTCGTGATGATACGGTCAATCTCAAGCGTTATTTCGATGTGGAG
ACCTATGAGACTCGAGGTTC

Product: hydrolase, TatD family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIEHALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLD
KLKHSKVVALGEIGLDYHWMTAPKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENKTAYTRYVVDFIADLRGMTTEEL
AVATTANAERIFGLDSK

Sequences:

>Translated_257_residues
MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIEHALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLD
KLKHSKVVALGEIGLDYHWMTAPKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENKTAYTRYVVDFIADLRGMTTEEL
AVATTANAERIFGLDSK
>Mature_257_residues
MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIEHALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLD
KLKHSKVVALGEIGLDYHWMTAPKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENKTAYTRYVVDFIADLRGMTTEEL
AVATTANAERIFGLDSK

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI225903424, Length=229, Percent_Identity=37.117903930131, Blast_Score=117, Evalue=8e-27,
Organism=Homo sapiens, GI14042943, Length=194, Percent_Identity=33.5051546391753, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI225903439, Length=181, Percent_Identity=33.1491712707182, Blast_Score=104, Evalue=9e-23,
Organism=Homo sapiens, GI110349730, Length=266, Percent_Identity=27.4436090225564, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI110349734, Length=266, Percent_Identity=27.4436090225564, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI226061853, Length=271, Percent_Identity=27.3062730627306, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI226061614, Length=257, Percent_Identity=26.8482490272374, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI226061595, Length=228, Percent_Identity=27.6315789473684, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1787342, Length=264, Percent_Identity=39.3939393939394, Blast_Score=185, Evalue=2e-48,
Organism=Escherichia coli, GI87082439, Length=255, Percent_Identity=31.3725490196078, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI48994985, Length=258, Percent_Identity=31.0077519379845, Blast_Score=134, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI17559024, Length=258, Percent_Identity=27.1317829457364, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71980746, Length=264, Percent_Identity=27.6515151515151, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17543026, Length=218, Percent_Identity=27.9816513761468, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17565396, Length=179, Percent_Identity=30.1675977653631, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI221330018, Length=199, Percent_Identity=33.1658291457286, Blast_Score=104, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24586117, Length=199, Percent_Identity=33.1658291457286, Blast_Score=104, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24648690, Length=287, Percent_Identity=29.616724738676, Blast_Score=103, Evalue=9e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 28875; Mature: 28875

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS01137 TATD_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIEHALELVDEYEQLYATI
CEECCCCCCCHHHHCCCCHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHH
GWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTAPKEVQEQVFRRQIQLSKD
CCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHCC
LDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLEWAEKFVDLGMTISFSGVVTF
CCCCEEEECHHHHHHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHHHCCCEEEECCEEEE
KKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENKTAYTRYVVDFIADLRGMTTEEL
HHHCCHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHE
AVATTANAERIFGLDSK
EEEECCCCHHEECCCCC
>Mature Secondary Structure
MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIEHALELVDEYEQLYATI
CEECCCCCCCHHHHCCCCHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHH
GWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTAPKEVQEQVFRRQIQLSKD
CCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHCC
LDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLEWAEKFVDLGMTISFSGVVTF
CCCCEEEECHHHHHHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHHHCCCEEEECCEEEE
KKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENKTAYTRYVVDFIADLRGMTTEEL
HHHCCHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHE
AVATTANAERIFGLDSK
EEEECCCCHHEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]