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The map label for this gene is spxA [H]

Identifier: 116516433

GI number: 116516433

Start: 183232

End: 183630

Strand: Direct

Name: spxA [H]

Synonym: SPD_0178

Alternate gene names: 116516433

Gene position: 183232-183630 (Clockwise)

Preceding gene: 116516135

Following gene: 116515403

Centisome position: 8.96

GC content: 39.1

Gene sequence:

>399_bases
ATGATTAAAATTTATACAGTCTCAAGTTGTACTAGCTGTAAAAAAGCAAAAACCTGGCTCAATGCCCACCAGTTAAGTTA
TAAAGAACAAAACCTTGGTAAAGAAGGAATTACGAGAGAAGAATTACTGGATATTCTAACCAAAACAGATAACGGAATAG
CCAGCATCGTTTCGTCTAAAAATCGCTATGCCAAAGCCCTTGGAGTGGATATTGAAGATTTGAGTGTCAATGAAGTTCTC
AATCTGATTATGGAAACACCGAGAATTTTAAAGAGCCCAATCCTTGTAGATGAAAAACGCCTGCAAGTTGGCTACAAGGA
AGACGATATTCGTGCCTTCCTACCACGCTCTGTCCGTAATGTAGAAAATGCAGAAGCACGTTTGCGTGCAGCTCTATAA

Upstream 100 bases:

>100_bases
GAAAAAAGTCAAAAAAAATTAAAAATAGGTCGCAAGTCGGATGTTTTTTATGGTATAATAGACTAAACTGATAGTAACAT
GTAGCGAAAGGGGTAGGTAC

Downstream 100 bases:

>100_bases
ACATCAAGGCTGGGAGCACTTCCCAGTCTTATTCTATTTTAATTTCAAAAAGAAAGAAGAAAGAAATGAAAAAAATAGTT
CTTGTTAGTCTAGCTTTCCT

Product: transcriptional regulator Spx

Products: NA

Alternate protein names: Thermoresistant insertional mutant protein A [H]

Number of amino acids: Translated: 132; Mature: 132

Protein sequence:

>132_residues
MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLDILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVL
NLIMETPRILKSPILVDEKRLQVGYKEDDIRAFLPRSVRNVENAEARLRAAL

Sequences:

>Translated_132_residues
MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLDILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVL
NLIMETPRILKSPILVDEKRLQVGYKEDDIRAFLPRSVRNVENAEARLRAAL
>Mature_132_residues
MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLDILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVL
NLIMETPRILKSPILVDEKRLQVGYKEDDIRAFLPRSVRNVENAEARLRAAL

Specific function: Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes invo

COG id: COG1393

COG function: function code P; Arsenate reductase and related proteins, glutaredoxin family

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsC family. Spx subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006660
- InterPro:   IPR012336
- InterPro:   IPR012335
- InterPro:   IPR006504 [H]

Pfam domain/function: PF03960 ArsC [H]

EC number: NA

Molecular weight: Translated: 14890; Mature: 14890

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLDILTKTDNGIASIVSSK
CEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHCC
NRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQVGYKEDDIRAFLPRSVRN
HHHHHHHCCCCCCCCHHHHHHHHHHCHHHHHCCCCCCHHHHHCCCCCCHHHHHHHHHHHH
VENAEARLRAAL
HHHHHHHHHHCC
>Mature Secondary Structure
MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLDILTKTDNGIASIVSSK
CEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHCC
NRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQVGYKEDDIRAFLPRSVRN
HHHHHHHCCCCCCCCHHHHHHHHHHCHHHHHCCCCCCHHHHHCCCCCCHHHHHHHHHHHH
VENAEARLRAAL
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471; 10048028 [H]