Click here to switch to the map view.

The map label for this gene is yqhT [H]

Identifier: 116516135

GI number: 116516135

Start: 182039

End: 183100

Strand: Direct

Name: yqhT [H]

Synonym: SPD_0177

Alternate gene names: 116516135

Gene position: 182039-183100 (Clockwise)

Preceding gene: 116517125

Following gene: 116516433

Centisome position: 8.9

GC content: 43.5

Gene sequence:

>1062_bases
ATGAATAAACGCGTACAAGCATTTCTAGCTAAAATGCAAGAAAAAGAACTAGATGGTATCATCATCAACAATCTTAAAAA
CGTCTATTATTTGACTGGTTTTTGGGGCTCAAACGGAACAGTCTTTATCAGCCGTGACCGTCAGGTCTTAGTGACAGACT
CTCGCTATATCATCGCAGCTAAGCAAGAAACCAGTGGTTTTGAGATTGTGGCTGATCGTGATGAATTGGCTGTCATTGCA
GGAATTGTTAAGGACATGGGCTTGACTCGTATCGGTTTTGAAGATGAGATTTCAGTGTCTTATTACCACCGTATGCAGGC
AGCTTTTGCAGGTTTGGACTTGCTTCCACAAACTCAGTTTGTGGAAGGTCTTCGTATGATTAAGGATGAGGCAGAGATTG
CAGCGATTCGCAAGGCTTGTTCTATCTCAGACCAAGCTTTCCGCGATGCGCTTGACTTTATCAAACCAGGAAAAACTGAA
ATTGAGATTGCCAACTTCCTTGATTTCCGCATGCGTGAGTTGGGAGCATCTGGCTTATCTTTTGATACGATCCTAGCTAG
CGGTATCAATTCTTCTAAACCCCATGCCCATCCAATGCACAAACCAGTGGAGTTGGGAGAAGCCATTACCATGGACTTCG
GCTGTCTCTATGACCACTATGTCAGTGATATGACCCGGACTATCTATCTAGGGCATGTTAGCGATGAGCAGGCAGAGATT
TACAATACGGTTCTAAAAGCTAACCAAGCCTTGATTGACCAAGCTAAGGCAGGCTTAGGTTTCCGTGACTTTGACAAAAT
CCCTCGTGATATTATCATTGAGGCAGGTTATGGTGACTACTTTACTCACGGCATTGGCCACGGTATTGGTCTGGATATCC
ATGAGGAACCCTACTTTAGCCAGACTTCTACAGAAACTATTAAGACAGGTATGGTCTTGACCGATGAACCAGGTATCTAT
ATCGAAGGCAAATATGGCGTTCGTATCGAGGATGATATCCTGATTACAGAGACAGGTTGTGAATTATTGACCCTAGCTCC
AAAAGAGTTGATAGTCATTTAG

Upstream 100 bases:

>100_bases
GGTGTCGGTGGTGGAACCATCATCGTAACAGGAACTCCAGAAGAAGTAGCTGCCAACGAAGCCAGCTATACAGGACACTA
TTTGAAAGGAAAGTTACATC

Downstream 100 bases:

>100_bases
TTGTTTGTCAAGAAAAAAGTACGAAAATGACGAAAAAAGTCAAAAAAAATTAAAAATAGGTCGCAAGTCGGATGTTTTTT
ATGGTATAATAGACTAAACT

Product: peptidase M24 family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFISRDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIA
GIVKDMGLTRIGFEDEISVSYYHRMQAAFAGLDLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYDHYVSDMTRTIYLGHVSDEQAEI
YNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAGYGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMVLTDEPGIY
IEGKYGVRIEDDILITETGCELLTLAPKELIVI

Sequences:

>Translated_353_residues
MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFISRDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIA
GIVKDMGLTRIGFEDEISVSYYHRMQAAFAGLDLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYDHYVSDMTRTIYLGHVSDEQAEI
YNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAGYGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMVLTDEPGIY
IEGKYGVRIEDDILITETGCELLTLAPKELIVI
>Mature_353_residues
MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFISRDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIA
GIVKDMGLTRIGFEDEISVSYYHRMQAAFAGLDLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYDHYVSDMTRTIYLGHVSDEQAEI
YNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAGYGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMVLTDEPGIY
IEGKYGVRIEDDILITETGCELLTLAPKELIVI

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=264, Percent_Identity=29.9242424242424, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI264681563, Length=251, Percent_Identity=29.8804780876494, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI93141226, Length=178, Percent_Identity=35.3932584269663, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI149589008, Length=288, Percent_Identity=26.0416666666667, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI260593665, Length=288, Percent_Identity=26.0416666666667, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI264681565, Length=248, Percent_Identity=28.2258064516129, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI164420681, Length=273, Percent_Identity=25.6410256410256, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI260593663, Length=231, Percent_Identity=26.8398268398268, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1788728, Length=350, Percent_Identity=38.2857142857143, Blast_Score=228, Evalue=3e-61,
Organism=Escherichia coli, GI1789275, Length=252, Percent_Identity=30.952380952381, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1790282, Length=292, Percent_Identity=26.027397260274, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17508215, Length=291, Percent_Identity=29.553264604811, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71989583, Length=266, Percent_Identity=25.187969924812, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17509539, Length=233, Percent_Identity=29.6137339055794, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6321118, Length=279, Percent_Identity=26.8817204301075, Blast_Score=96, Evalue=9e-21,
Organism=Saccharomyces cerevisiae, GI6320922, Length=273, Percent_Identity=27.8388278388278, Blast_Score=84, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6322999, Length=189, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=2e-16,
Organism=Drosophila melanogaster, GI19920384, Length=269, Percent_Identity=29.7397769516729, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI21357079, Length=288, Percent_Identity=30.9027777777778, Blast_Score=111, Evalue=8e-25,
Organism=Drosophila melanogaster, GI17137632, Length=363, Percent_Identity=24.7933884297521, Blast_Score=72, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 39370; Mature: 39370

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFISRDRQVLVTDSRYIIAA
CCHHHHHHHHHHHHHHCCCEEEECCCCEEEEEEEECCCCEEEEECCCEEEEECCEEEEEE
KQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYYHRMQAAFAGLDLLPQTQF
ECCCCCEEEEECCCHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHH
VEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTEIEIANFLDFRMRELGASGLS
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCCCCC
FDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYDHYVSDMTRTIYLGHVSDEQAEI
HHHHHHCCCCCCCCCCCCCCCCHHHCCEEEEHHHHHHHHHHHCCEEEEEEEECCCHHHHH
YNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAGYGDYFTHGIGHGIGLDIHEEPYFS
HHHHHHHHHHHHHHHHHCCCCHHHHHCCCEEEEECCCCCHHHHHCCCCCCCCCCCCCCCC
QTSTETIKTGMVLTDEPGIYIEGKYGVRIEDDILITETGCELLTLAPKELIVI
CCCCHHHHCCEEEECCCCEEEECCCCCEEECCEEEEECCCCEEEECCCEEEEC
>Mature Secondary Structure
MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFISRDRQVLVTDSRYIIAA
CCHHHHHHHHHHHHHHCCCEEEECCCCEEEEEEEECCCCEEEEECCCEEEEECCEEEEEE
KQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYYHRMQAAFAGLDLLPQTQF
ECCCCCEEEEECCCHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHH
VEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTEIEIANFLDFRMRELGASGLS
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCCCCC
FDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYDHYVSDMTRTIYLGHVSDEQAEI
HHHHHHCCCCCCCCCCCCCCCCHHHCCEEEEHHHHHHHHHHHCCEEEEEEEECCCHHHHH
YNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAGYGDYFTHGIGHGIGLDIHEEPYFS
HHHHHHHHHHHHHHHHHCCCCHHHHHCCCEEEEECCCCCHHHHHCCCCCCCCCCCCCCCC
QTSTETIKTGMVLTDEPGIYIEGKYGVRIEDDILITETGCELLTLAPKELIVI
CCCCHHHHCCEEEECCCCEEEECCCCCEEECCEEEEECCCCEEEECCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]