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The map label for this gene is tdk

Identifier: 116516420

GI number: 116516420

Start: 916739

End: 917338

Strand: Direct

Name: tdk

Synonym: SPD_0904

Alternate gene names: 116516420

Gene position: 916739-917338 (Clockwise)

Preceding gene: 116516238

Following gene: 116516070

Centisome position: 44.8

GC content: 44.33

Gene sequence:

>600_bases
ATGGCACAGTTGTACTATCGTTATGGGACCATGAACTCTGGTAAAACGATTGAGATTCTCAAAGTGGCCTATAACTACGA
GGAGCAAGGAAAAGGTGTTGTCATTATGACCTCGGCTCTGGATACGCGTGACGGTGTTGGCTATGTGTCGAGTCGAATTG
GCATGAAACGCCCTGCCCTTGCGATTGAGGAAACAACGGATATCTTTGGCTATATCCGAGACCTACCAGAAAAACCTTAC
TGTGTTTTGGTCGATGAAGCCCAGTTTCTTAAACGCCACCATGTTTACGACCTAGCTCGTGTTGTGGACGAGTTAGACAT
ACCCGTCATGGCTTTTGGCTTGAAAAATGACTTTCGCAATGAATTGTTCGAAGGTTCCAAATATCTCTTGCTTTTAGCGG
ACAAGATTGACGAAATCAAGACCATCTGTCAGTATTGCAAGAAAAAGGCGACCATGGTGTTGCGAACACAGGATGGACTG
CCCGTTTACGATGGAGAACAGATCCAGATTGGTGGTAATGAAACCTATATCTCGGTTTGCCGTAAACATTATTTTGCGCC
AATGATAACCTCTAACAAGGAGCAAAACTATGACAATTGA

Upstream 100 bases:

>100_bases
GATTTCTTCCATTTTACCACATTTTGCCGTTTAAAGCTTAAGAAAATTATGATATACTAGAATGTAGCAAAAATTTAGAA
ATGGACGTGAAGCAAGAAAC

Downstream 100 bases:

>100_bases
ACTAAGAGATGTTACAATGGAAAATTATTTTGATGTTTTAAATTTGGATGTCAAGGAATATCAAAAACAATTCATTGCAA
CCAACGCAATTAGTTTAGCT

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRDGVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPY
CVLVDEAQFLKRHHVYDLARVVDELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
PVYDGEQIQIGGNETYISVCRKHYFAPMITSNKEQNYDN

Sequences:

>Translated_199_residues
MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRDGVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPY
CVLVDEAQFLKRHHVYDLARVVDELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
PVYDGEQIQIGGNETYISVCRKHYFAPMITSNKEQNYDN
>Mature_198_residues
AQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRDGVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYC
VLVDEAQFLKRHHVYDLARVVDELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGLP
VYDGEQIQIGGNETYISVCRKHYFAPMITSNKEQNYDN

Specific function: Phosphorylates Both Thymidine And Deoxyuridine. [C]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family

Homologues:

Organism=Escherichia coli, GI1787490, Length=187, Percent_Identity=54.0106951871658, Blast_Score=206, Evalue=1e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KITH_STRPN (Q97R22)

Other databases:

- EMBL:   AE005672
- PIR:   B97987
- PIR:   D95117
- RefSeq:   NP_345493.1
- ProteinModelPortal:   Q97R22
- SMR:   Q97R22
- EnsemblBacteria:   EBSTRT00000025720
- GeneID:   931532
- GenomeReviews:   AE005672_GR
- KEGG:   spn:SP_1018
- TIGR:   SP_1018
- GeneTree:   EBGT00050000028198
- HOGENOM:   HBG522108
- OMA:   FRYGAMN
- ProtClustDB:   PRK04296
- BioCyc:   SPNE170187-1:SP_1018-MONOMER
- BRENDA:   2.7.1.21
- GO:   GO:0005737
- HAMAP:   MF_00124
- InterPro:   IPR001267
- InterPro:   IPR020633
- InterPro:   IPR020634
- PANTHER:   PTHR11441
- PIRSF:   PIRSF035805

Pfam domain/function: PF00265 TK

EC number: =2.7.1.21

Molecular weight: Translated: 22827; Mature: 22695

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS00603 TK_CELLULAR_TYPE

Important sites: ACT_SITE 86-86

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRDGVGYVSSRIGMKRPAL
CCEEEEEECCCCCCCEEEEEEEEECHHHCCCEEEEEEECCCCCCCCHHHHHHCCCCCCCE
AIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVVDELDIPVMAFGLKNDFRN
EEHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHH
ELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGLPVYDGEQIQIGGNETYISVC
HHHCCCCEEEEEEHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCEEEECCCHHHHHHH
RKHYFAPMITSNKEQNYDN
HHHHCCCCEECCCCCCCCC
>Mature Secondary Structure 
AQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRDGVGYVSSRIGMKRPAL
CEEEEEECCCCCCCEEEEEEEEECHHHCCCEEEEEEECCCCCCCCHHHHHHCCCCCCCE
AIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVVDELDIPVMAFGLKNDFRN
EEHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHH
ELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGLPVYDGEQIQIGGNETYISVC
HHHCCCCEEEEEEHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCEEEECCCHHHHHHH
RKHYFAPMITSNKEQNYDN
HHHHCCCCEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11463916