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The map label for this gene is glpO [H]

Identifier: 116516239

GI number: 116516239

Start: 1987848

End: 1989674

Strand: Reverse

Name: glpO [H]

Synonym: SPD_2012

Alternate gene names: 116516239

Gene position: 1989674-1987848 (Counterclockwise)

Preceding gene: 116516212

Following gene: 116516308

Centisome position: 97.24

GC content: 44.55

Gene sequence:

>1827_bases
ATGGAATTTTCAAAAAAAACACGTGAATTGTCAATTAAAAAAATGCAGGAACGCACCCTGGACCTCTTGATTATCGGTGG
AGGAATCACAGGAGCTGGTGTAGCCTTGCAGGCGGCAGCTAGCGGTCTTGAGACTGGTTTGATTGAAATGCAAGACTTTG
CAGAAGGAACATCTAGTCGTTCAACAAAATTGGTTCACGGAGGTCTTCGCTACCTCAAACAATTCGACGTAGAAGTGGTC
TCAGATACGGTTTCTGAACGTGCAGTGGTTCAACAAATCGCTCCACACATTCCAAAACCAGATCCAATGCTCTTACCAGT
TTACGATGAAGATGGAGCAACCTTTAGCCTCTTCCGTCTTAAAGTAGCCATGGACTTGTACGACCTCTTGGCAGGTGTTA
GCAACACACCAACTGCGAACAAGGTTTTGAGCAAGGATCAAGTCTTGGAACGCCAGCCAAACTTGAAGAAGGAAGGCTTG
GTAGGAGGTGGAGTGTATCTTGACTTCCGTAACAACGATGCGCGTCTCGTGATTGAAAACATCAAACGTGCCAACCAAGA
CGGTGCCCTCATTGCCAACCACGTGAAGGCAGAAGGCTTCCTCTTTGACGAAAGTGGCAAGATTACAGGTGTTGTAGCTC
GTGATCTCTTGACAGACCAAGTATTTGAAATCAAGGCCCGTCTGGTTATTAATACAACAGGTCCTTGGAGTGATAAAGTA
CGTAATTTGTCTAATAAGGGAACGCAATTCTCACAAATGCGCCCAACTAAGGGAGTTCACTTGGTAGTGGATTCAAGCAA
AATCAAGGTTTCACAGCCAGTTTACTTTGACACAGGTTTGGGTGACGGTCGTATGGTCTTTGTTCTCCCACGTGAAAACA
AGACTTACTTTGGTACAACTGATACAGACTACACAGGTGATTTGGAGCATCCAAAAGTAACTCAAGAAGATGTAGATTAT
CTACTTGGCATTGTCAACAACCGCTTTCCAGAATCCAACATCACCATTGATGATATCGAAAGCAGCTGGGCAGGTCTTCG
TCCATTGATTGCAGGGAACAGTGCCTCTGACTATAATGGTGGAAATAACGGTACCATCAGTGATGAAAGCTTTGACAACT
TGATTGCGACTGTTGAATCTTATCTCTCCAAAGAAAAAACACGTGAAGATGTTGAGTCTGCTGTCAGCAAGCTTGAAAGT
AGCACATCTGAGAAACATTTGGATCCATCTGCAGTTTCTCGTGGGTCTAGCTTGGATCGTGATGACAATGGTCTTTTGAC
TCTTGCTGGCGGTAAAATCACAGACTACCGTAAGATGGCTGAAGGAGCTATGGAGCGCGTGGTTGACATCCTCAAAGCAG
AATTTGACCGTAGCTTTAAATTGATCAATTCTAAAACTTACCCTGTTTCAGGTGGAGAATTGAACCCAGCAAATGTGGAT
TCAGAAATCGAAGCCTTTGCGCAACTTGGAGTTTCACGTGGTTTGGATAGCAAGGAAGCTCATTACCTAGCAAATCTTTA
CGGTTCAAATGCACCGAAGGTCTTTGCACTTGCTCACAGCTTGGAACAAGCGCCAGGACTCAGCTTGGCAGATACTTTGT
CCCTTCACTATGCAATGCGCAACGAGTTGGCTCTTAGCCCAGTTGACTTCCTTCTTCGTCGTACCAACCATATGCTCTTT
ATGCGTGATAGCTTGGATAGCATCGTTGAGCCAGTTTTGGATGAAATGGGACGATTCTATGACTGGACAGAAGAAGAAAA
AGCAACTTACCGTGCTGATGTCGAAGCAGCTCTCGCTAACAACGATTTAGCAGAATTAAAAAATTAA

Upstream 100 bases:

>100_bases
ACAAGGGCTGGAAGAAGGCTGTGAAAGCAACTCAAGTCTTTGCGGAAGTAGACGACTAATACTGGCAGAATAAAGCGATT
TATTTAGAAAGTGTGTAAAT

Downstream 100 bases:

>100_bases
GAAAAAATAAAAGAGGTGGAGGGCAGCATTCCTTGTCGCCCGTCCCTTCTTTTTAATGGAGACAGAAAGATGATGAATGA
ATTATTTGGAGAATTTCTAG

Product: alpha-glycerophosphate oxidase

Products: NA

Alternate protein names: Exported protein 6; Glycerol-3-phosphate oxidase [H]

Number of amino acids: Translated: 608; Mature: 608

Protein sequence:

>608_residues
MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLETGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVV
SDTVSERAVVQQIAPHIPKPDPMLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKDQVLERQPNLKKEGL
VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLTDQVFEIKARLVINTTGPWSDKV
RNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYFDTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDY
LLGIVNNRFPESNITIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVESAVSKLES
STSEKHLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDILKAEFDRSFKLINSKTYPVSGGELNPANVD
SEIEAFAQLGVSRGLDSKEAHYLANLYGSNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLF
MRDSLDSIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN

Sequences:

>Translated_608_residues
MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLETGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVV
SDTVSERAVVQQIAPHIPKPDPMLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKDQVLERQPNLKKEGL
VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLTDQVFEIKARLVINTTGPWSDKV
RNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYFDTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDY
LLGIVNNRFPESNITIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVESAVSKLES
STSEKHLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDILKAEFDRSFKLINSKTYPVSGGELNPANVD
SEIEAFAQLGVSRGLDSKEAHYLANLYGSNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLF
MRDSLDSIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN
>Mature_608_residues
MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLETGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVV
SDTVSERAVVQQIAPHIPKPDPMLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKDQVLERQPNLKKEGL
VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLTDQVFEIKARLVINTTGPWSDKV
RNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYFDTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDY
LLGIVNNRFPESNITIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVESAVSKLES
STSEKHLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDILKAEFDRSFKLINSKTYPVSGGELNPANVD
SEIEAFAQLGVSRGLDSKEAHYLANLYGSNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLF
MRDSLDSIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=605, Percent_Identity=32.2314049586777, Blast_Score=261, Evalue=2e-69,
Organism=Homo sapiens, GI285002231, Length=605, Percent_Identity=32.2314049586777, Blast_Score=261, Evalue=2e-69,
Organism=Escherichia coli, GI2367226, Length=410, Percent_Identity=28.780487804878, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI1788574, Length=418, Percent_Identity=25.3588516746411, Blast_Score=83, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17509253, Length=606, Percent_Identity=31.023102310231, Blast_Score=226, Evalue=3e-59,
Organism=Caenorhabditis elegans, GI115534726, Length=610, Percent_Identity=29.1803278688525, Blast_Score=219, Evalue=4e-57,
Organism=Saccharomyces cerevisiae, GI6322036, Length=642, Percent_Identity=29.7507788161994, Blast_Score=209, Evalue=8e-55,
Organism=Drosophila melanogaster, GI161077125, Length=609, Percent_Identity=29.5566502463054, Blast_Score=214, Evalue=1e-55,
Organism=Drosophila melanogaster, GI24653942, Length=609, Percent_Identity=29.5566502463054, Blast_Score=214, Evalue=1e-55,
Organism=Drosophila melanogaster, GI24653944, Length=609, Percent_Identity=29.5566502463054, Blast_Score=214, Evalue=1e-55,
Organism=Drosophila melanogaster, GI20130025, Length=609, Percent_Identity=29.5566502463054, Blast_Score=214, Evalue=1e-55,
Organism=Drosophila melanogaster, GI24586295, Length=357, Percent_Identity=33.3333333333333, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI19921278, Length=609, Percent_Identity=25.944170771757, Blast_Score=161, Evalue=2e-39,
Organism=Drosophila melanogaster, GI45550977, Length=456, Percent_Identity=23.2456140350877, Blast_Score=101, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.3.21 [H]

Molecular weight: Translated: 66793; Mature: 66793

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00977 FAD_G3PDH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLETGLIEMQDFAEGTSSR
CCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHCHHHHHHHHCCCCCC
STKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDPMLLPVYDEDGATFSLFRL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEHHHH
KVAMDLYDLLAGVSNTPTANKVLSKDQVLERQPNLKKEGLVGGGVYLDFRNNDARLVIEN
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEECEEEEEEECCCCEEHHHH
IKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLTDQVFEIKARLVINTTGPWSDKV
HHHCCCCCCEEEEEEECCCEEECCCCCEEHHHHHHHHHHHHHEEEEEEEEECCCCCHHHH
RNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYFDTGLGDGRMVFVLPRENKTYFGTT
HHHHCCCCCHHHCCCCCCEEEEEECCCEEECCCEEEECCCCCCEEEEEEECCCCEEECCC
DTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNITIDDIESSWAGLRPLIAGNSASDYNG
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCC
GNNGTISDESFDNLIATVESYLSKEKTREDVESAVSKLESSTSEKHLDPSAVSRGSSLDR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHCCCCCCC
DDNGLLTLAGGKITDYRKMAEGAMERVVDILKAEFDRSFKLINSKTYPVSGGELNPANVD
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCC
SEIEAFAQLGVSRGLDSKEAHYLANLYGSNAPKVFALAHSLEQAPGLSLADTLSLHYAMR
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHH
NELALSPVDFLLRRTNHMLFMRDSLDSIVEPVLDEMGRFYDWTEEEKATYRADVEAALAN
HCCCCCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
NDLAELKN
CCHHHHCC
>Mature Secondary Structure
MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLETGLIEMQDFAEGTSSR
CCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHCHHHHHHHHCCCCCC
STKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDPMLLPVYDEDGATFSLFRL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEHHHH
KVAMDLYDLLAGVSNTPTANKVLSKDQVLERQPNLKKEGLVGGGVYLDFRNNDARLVIEN
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEECEEEEEEECCCCEEHHHH
IKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLTDQVFEIKARLVINTTGPWSDKV
HHHCCCCCCEEEEEEECCCEEECCCCCEEHHHHHHHHHHHHHEEEEEEEEECCCCCHHHH
RNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYFDTGLGDGRMVFVLPRENKTYFGTT
HHHHCCCCCHHHCCCCCCEEEEEECCCEEECCCEEEECCCCCCEEEEEEECCCCEEECCC
DTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNITIDDIESSWAGLRPLIAGNSASDYNG
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCC
GNNGTISDESFDNLIATVESYLSKEKTREDVESAVSKLESSTSEKHLDPSAVSRGSSLDR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHCCCCCCC
DDNGLLTLAGGKITDYRKMAEGAMERVVDILKAEFDRSFKLINSKTYPVSGGELNPANVD
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCC
SEIEAFAQLGVSRGLDSKEAHYLANLYGSNAPKVFALAHSLEQAPGLSLADTLSLHYAMR
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHH
NELALSPVDFLLRRTNHMLFMRDSLDSIVEPVLDEMGRFYDWTEEEKATYRADVEAALAN
HCCCCCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
NDLAELKN
CCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9726992; 11463916; 7934910 [H]