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The map label for this gene is dinP

Identifier: 116516092

GI number: 116516092

Start: 418187

End: 419248

Strand: Reverse

Name: dinP

Synonym: SPD_0419

Alternate gene names: 116516092

Gene position: 419248-418187 (Counterclockwise)

Preceding gene: 116516200

Following gene: 116517055

Centisome position: 20.49

GC content: 40.68

Gene sequence:

>1062_bases
ATGTTGATTTTTCCTTTGTTAAATGATTTGTCAAGAAAAATCATCCATATTGACATGGATGCCTTTTTTGCTGCGGTGGA
AATCAAGGATAATCCTAAACTCAGAGGAAAACCTGTCATTATTGGAAGCGACCCTCGACAAACAGGTGGGCGGGGAGTCG
TTTCTACCTGTAGCTATGAGGCTCGAGCTTTTGGTGTCCATTCTGCCATGAGTTCCAAGGAAGCTTATGAACGTTGTCCC
CAGGCCGTCTTTATCTCAGGAAATTATGAGAAATACAAAGCTGTGGGACTCCAGATTCGAGCTATTTTTAAGCGCTATAC
AGATTTGATTGAACCCATGAGTATTGACGAAGCCTATTTGGATGTGACAGAAAATAAACTCGGTATCAAGTCAGCGGTCA
AAATTGCTCGCCTCATTCAAAAAGATATCTGGCAAGAACTCCATCTAACTGCTTCTGCCGGTATTTCCTATAACAAGTTC
TTAGCTAAAATGGCGAGTGATTATCAAAAACCTCATGGTTTGACAGTGATTCTACCTGAACAGGCTGAGGATTTTCTCAA
ACAAATGGATATTTCCAAATTTCATGGAGTAGGAAAAAAGACAGTAGAACGTCTTCATCAAATGGGCGTTTTTACTGGTG
CTGATTTACTTGAAGTTCCTGAGGTGACCCTAATAGACCGTTTTGGTAGACTAGGCTATGATCTGTATCGAAAGGCTCGT
GGCATTCACAACTCTCCAGTCAAATCCAATCGCATCCGTAAATCAATCGGCAAGGAGAAAACCTACGGGAAGATTCTCCG
TGCTGAGGAAGATATCAAAAAAGAGCTGACTCTTCTATCAGAAAAAGTCGCTCTCAATCTACATCAACAAGAAAAAGCTG
GAAAAATTGTCATTTTGAAAATCCGCTACGAGGACTTTTCAACTCTTACCAAACGAAAAAGTATTGCTCAAAAAACACAA
GATGCTAGTCAGATAAGCCAAATAGCCCTGCAACTCTATGAAGAATTAAGTGAGAAAGAAAGAGGTGTCCGCCTATTGGG
GATTACCATGACTGGATTTTAA

Upstream 100 bases:

>100_bases
ATAGAACTGACGAAGTCAGCTCAAAATACTGTTTTGAGGTTGCAGATGGAAGCTGACGTGGTTTGAAGAGATTTTTGAAA
AGTATAAAAAGGTGCTAGGC

Downstream 100 bases:

>100_bases
AGCTCAATGAAAATCAAAGAGCAAACTAGGAGGCTAGCCGCAGGCTGCTCAAAACACTGTTTTGAGGTTGCAGATAAAGC
TGACGCGGTTTGAAGAGATT

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MLIFPLLNDLSRKIIHIDMDAFFAAVEIKDNPKLRGKPVIIGSDPRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCP
QAVFISGNYEKYKAVGLQIRAIFKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLEVPEVTLIDRFGRLGYDLYRKAR
GIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKELTLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSIAQKTQ
DASQISQIALQLYEELSEKERGVRLLGITMTGF

Sequences:

>Translated_353_residues
MLIFPLLNDLSRKIIHIDMDAFFAAVEIKDNPKLRGKPVIIGSDPRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCP
QAVFISGNYEKYKAVGLQIRAIFKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLEVPEVTLIDRFGRLGYDLYRKAR
GIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKELTLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSIAQKTQ
DASQISQIALQLYEELSEKERGVRLLGITMTGF
>Mature_353_residues
MLIFPLLNDLSRKIIHIDMDAFFAAVEIKDNPKLRGKPVIIGSDPRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCP
QAVFISGNYEKYKAVGLQIRAIFKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLEVPEVTLIDRFGRLGYDLYRKAR
GIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKELTLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSIAQKTQ
DASQISQIALQLYEELSEKERGVRLLGITMTGF

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain

Homologues:

Organism=Homo sapiens, GI84043967, Length=338, Percent_Identity=29.2899408284024, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI7706681, Length=339, Percent_Identity=29.2035398230088, Blast_Score=141, Evalue=9e-34,
Organism=Homo sapiens, GI154350220, Length=322, Percent_Identity=27.3291925465839, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI7705344, Length=115, Percent_Identity=44.3478260869565, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI5729982, Length=396, Percent_Identity=26.5151515151515, Blast_Score=101, Evalue=1e-21,
Organism=Escherichia coli, GI1786425, Length=348, Percent_Identity=40.8045977011494, Blast_Score=238, Evalue=3e-64,
Organism=Escherichia coli, GI1787432, Length=212, Percent_Identity=29.2452830188679, Blast_Score=88, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI193205700, Length=417, Percent_Identity=29.4964028776978, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17537959, Length=369, Percent_Identity=26.2872628726287, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI193205702, Length=347, Percent_Identity=26.5129682997118, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI115534089, Length=125, Percent_Identity=39.2, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI19923006, Length=412, Percent_Identity=24.5145631067961, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI21355641, Length=351, Percent_Identity=27.6353276353276, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24644984, Length=351, Percent_Identity=27.6353276353276, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24668444, Length=127, Percent_Identity=34.6456692913386, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DPO4_STRP2 (Q04M21)

Other databases:

- EMBL:   CP000410
- RefSeq:   YP_815927.1
- ProteinModelPortal:   Q04M21
- SMR:   Q04M21
- STRING:   Q04M21
- EnsemblBacteria:   EBSTRT00000018977
- GeneID:   4442686
- GenomeReviews:   CP000410_GR
- KEGG:   spd:SPD_0419
- eggNOG:   COG0389
- GeneTree:   EBGT00050000028150
- HOGENOM:   HBG734504
- OMA:   VICAASY
- ProtClustDB:   PRK02406
- GO:   GO:0005737
- HAMAP:   MF_01113
- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880
- Gene3D:   G3DSA:3.30.1490.100
- PANTHER:   PTHR11076

Pfam domain/function: PF00817 IMS; SSF100879 DNA_pol_Y-fam_little_finger

EC number: =2.7.7.7

Molecular weight: Translated: 39895; Mature: 39895

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: PS50173 UMUC

Important sites: ACT_SITE 117-117

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIFPLLNDLSRKIIHIDMDAFFAAVEIKDNPKLRGKPVIIGSDPRQTGGRGVVSTCSYE
CEEEHHHHHHHHHEEEEEHHHEEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCHHCCCH
ARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKAVGLQIRAIFKRYTDLIEPMSIDEAYL
HHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
DVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKFLAKMASDYQKPHGLTVILPE
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECH
QAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLEVPEVTLIDRFGRLGYDLYRKAR
HHHHHHHHHCHHHHHCCCHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHC
GIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKELTLLSEKVALNLHQQEKAGKIVILK
CCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
IRYEDFSTLTKRKSIAQKTQDASQISQIALQLYEELSEKERGVRLLGITMTGF
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCC
>Mature Secondary Structure
MLIFPLLNDLSRKIIHIDMDAFFAAVEIKDNPKLRGKPVIIGSDPRQTGGRGVVSTCSYE
CEEEHHHHHHHHHEEEEEHHHEEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCHHCCCH
ARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKAVGLQIRAIFKRYTDLIEPMSIDEAYL
HHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
DVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKFLAKMASDYQKPHGLTVILPE
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECH
QAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLEVPEVTLIDRFGRLGYDLYRKAR
HHHHHHHHHCHHHHHCCCHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHC
GIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKELTLLSEKVALNLHQQEKAGKIVILK
CCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
IRYEDFSTLTKRKSIAQKTQDASQISQIALQLYEELSEKERGVRLLGITMTGF
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA