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The map label for this gene is cps2K [H]

Identifier: 116516033

GI number: 116516033

Start: 325843

End: 327081

Strand: Direct

Name: cps2K [H]

Synonym: SPD_0326

Alternate gene names: 116516033

Gene position: 325843-327081 (Clockwise)

Preceding gene: 116516835

Following gene: 116517147

Centisome position: 15.92

GC content: 36.56

Gene sequence:

>1239_bases
GTGAAAATAGCAGTAGCAGGTACGGGATATGTTGGTCTATCCATTGCAGTTTTATTGTCTCAACAACATCAAGTAATGGC
GGTGGACATTATTCCTGAGAAGGTCGAATTAATTAATCAAAGAAAGTCACCTATTCAAGATGACTATATAGAGAAATATC
TGGCAAAAAAGGATTTAAATTTAGTGGCTACATTGGATGCAAAAGAAGCATATCAAGATGCGGATTTTGTTGTGATTGCA
GCTCCAACTAACTATGATCCAAAGAAGAACTTTTTTGACACTTCTGCTGTAGAGTCTGTCATTGAAACGGCGCTTAAATA
TAATCCAGATGCCATCATGGTCATTAAAAGTACAGTTCCAGTTGGTTATACAGAGTCAGCTCGAAAGAAATTTCAGACTG
AAAATATCTTATTTAGTCCTGAATTTTTGCGTGAGTCAAAGGCGCTTTACGATAACTTATATCCCAGCCGTATTATTTTA
GGGACAGATAAAAATAATGAACGCTTGGTAAGTGCTGCTGAGACATTTGCGAGATTGCTCCAAGAAGGCGCTTTAAAAGA
AAACATTGATACATTATACATGGGCTTTACTGAAGCTGAGGCGGTCAAGCTTTTTGCAAATACTTACCTTGCTTTGCGTG
TTTCTTATTTTAATGAGCTGGATACTTATTCTGAGATGAAGGGGCTAGACACTCAAGCTATTATTGATGGAGTTGGTTTG
GATCCCCGTATTGGTTCGCACTACAACAATCCTTCCTTCGGCTATGGTGGCTATTGTCTTCCTAAAGATACCAAGCAACT
TCTTGCCAACTATGAAGATATACCAGAAGAACTTATAGGAGCCATAGTACGGAGCAATTCGACACGTAAAGACTTTATTG
CTGATCAGGTTCTTAAGATGGTAGATTATTATGATTATTCAGCCCATAATATTTTCGATGAGAGAGTAGAAAAAGATATT
ATTATTGGCATCTATAGATTGACCATGAAGAGTAATAGCGATAATTTTCGTCAAAGCTCTATTCAAGGTATTATGAAACG
TATAAAAGCTAAGGGAGTAAGAGTAGTTATTTATGAACCCACTTTAGAAAGCGGGAGTACATTTTTTGGAAGTTCCGTTA
TCAATGATTTAGAGGAATTCAAACGACTGAGTAATGCCATTGTTGCTAATCGCTATGATAACTCATTAGAAGATGTCAAG
GAAAAAGTCTATACACGTGATATTTTTGAAAGAGATTAA

Upstream 100 bases:

>100_bases
TAGTTATGTTATTTTATAAAGAAATAAAGAGTATTATTGGTGAATTAAAAAAGTTTCTAACATAAGAACCAATAAGTACG
AGTATTGAAAGGAGAAAAAT

Downstream 100 bases:

>100_bases
TTTAGTATAATAAAAATGAAAAAAATAATTGTTAGAAGCGGTCCATACTGAGAAGCAATGGGAACGCTCAGCGACAGAAC
TTCCTCCATTTATCATTAAA

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MKIAVAGTGYVGLSIAVLLSQQHQVMAVDIIPEKVELINQRKSPIQDDYIEKYLAKKDLNLVATLDAKEAYQDADFVVIA
APTNYDPKKNFFDTSAVESVIETALKYNPDAIMVIKSTVPVGYTESARKKFQTENILFSPEFLRESKALYDNLYPSRIIL
GTDKNNERLVSAAETFARLLQEGALKENIDTLYMGFTEAEAVKLFANTYLALRVSYFNELDTYSEMKGLDTQAIIDGVGL
DPRIGSHYNNPSFGYGGYCLPKDTKQLLANYEDIPEELIGAIVRSNSTRKDFIADQVLKMVDYYDYSAHNIFDERVEKDI
IIGIYRLTMKSNSDNFRQSSIQGIMKRIKAKGVRVVIYEPTLESGSTFFGSSVINDLEEFKRLSNAIVANRYDNSLEDVK
EKVYTRDIFERD

Sequences:

>Translated_412_residues
MKIAVAGTGYVGLSIAVLLSQQHQVMAVDIIPEKVELINQRKSPIQDDYIEKYLAKKDLNLVATLDAKEAYQDADFVVIA
APTNYDPKKNFFDTSAVESVIETALKYNPDAIMVIKSTVPVGYTESARKKFQTENILFSPEFLRESKALYDNLYPSRIIL
GTDKNNERLVSAAETFARLLQEGALKENIDTLYMGFTEAEAVKLFANTYLALRVSYFNELDTYSEMKGLDTQAIIDGVGL
DPRIGSHYNNPSFGYGGYCLPKDTKQLLANYEDIPEELIGAIVRSNSTRKDFIADQVLKMVDYYDYSAHNIFDERVEKDI
IIGIYRLTMKSNSDNFRQSSIQGIMKRIKAKGVRVVIYEPTLESGSTFFGSSVINDLEEFKRLSNAIVANRYDNSLEDVK
EKVYTRDIFERD
>Mature_412_residues
MKIAVAGTGYVGLSIAVLLSQQHQVMAVDIIPEKVELINQRKSPIQDDYIEKYLAKKDLNLVATLDAKEAYQDADFVVIA
APTNYDPKKNFFDTSAVESVIETALKYNPDAIMVIKSTVPVGYTESARKKFQTENILFSPEFLRESKALYDNLYPSRIIL
GTDKNNERLVSAAETFARLLQEGALKENIDTLYMGFTEAEAVKLFANTYLALRVSYFNELDTYSEMKGLDTQAIIDGVGL
DPRIGSHYNNPSFGYGGYCLPKDTKQLLANYEDIPEELIGAIVRSNSTRKDFIADQVLKMVDYYDYSAHNIFDERVEKDI
IIGIYRLTMKSNSDNFRQSSIQGIMKRIKAKGVRVVIYEPTLESGSTFFGSSVINDLEEFKRLSNAIVANRYDNSLEDVK
EKVYTRDIFERD

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=385, Percent_Identity=27.5324675324675, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI296040438, Length=263, Percent_Identity=30.0380228136882, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI296040443, Length=233, Percent_Identity=29.1845493562232, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1788340, Length=412, Percent_Identity=59.4660194174757, Blast_Score=496, Evalue=1e-142,
Organism=Escherichia coli, GI48994968, Length=425, Percent_Identity=25.4117647058824, Blast_Score=75, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17560350, Length=402, Percent_Identity=29.3532338308458, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI17136908, Length=387, Percent_Identity=27.1317829457364, Blast_Score=119, Evalue=6e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 46614; Mature: 46614

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAVAGTGYVGLSIAVLLSQQHQVMAVDIIPEKVELINQRKSPIQDDYIEKYLAKKDLN
CEEEEECCCHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHCCCCCCHHHHHHHHHHCCCC
LVATLDAKEAYQDADFVVIAAPTNYDPKKNFFDTSAVESVIETALKYNPDAIMVIKSTVP
EEEEECHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCC
VGYTESARKKFQTENILFSPEFLRESKALYDNLYPSRIILGTDKNNERLVSAAETFARLL
CCCCHHHHHHHCCCCEEECHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHH
QEGALKENIDTLYMGFTEAEAVKLFANTYLALRVSYFNELDTYSEMKGLDTQAIIDGVGL
HHCCHHHCCHHEEECCCHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHCCCHHHHHCCCCC
DPRIGSHYNNPSFGYGGYCLPKDTKQLLANYEDIPEELIGAIVRSNSTRKDFIADQVLKM
CCCCCCCCCCCCCCCCCEECCHHHHHHHHCHHCCHHHHHHHHHHCCCCHHHHHHHHHHHH
VDYYDYSAHNIFDERVEKDIIIGIYRLTMKSNSDNFRQSSIQGIMKRIKAKGVRVVIYEP
HHHCCCCHHHHHHHHHCHHHEEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEECC
TLESGSTFFGSSVINDLEEFKRLSNAIVANRYDNSLEDVKEKVYTRDIFERD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIAVAGTGYVGLSIAVLLSQQHQVMAVDIIPEKVELINQRKSPIQDDYIEKYLAKKDLN
CEEEEECCCHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHCCCCCCHHHHHHHHHHCCCC
LVATLDAKEAYQDADFVVIAAPTNYDPKKNFFDTSAVESVIETALKYNPDAIMVIKSTVP
EEEEECHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCC
VGYTESARKKFQTENILFSPEFLRESKALYDNLYPSRIILGTDKNNERLVSAAETFARLL
CCCCHHHHHHHCCCCEEECHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHH
QEGALKENIDTLYMGFTEAEAVKLFANTYLALRVSYFNELDTYSEMKGLDTQAIIDGVGL
HHCCHHHCCHHEEECCCHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHCCCHHHHHCCCCC
DPRIGSHYNNPSFGYGGYCLPKDTKQLLANYEDIPEELIGAIVRSNSTRKDFIADQVLKM
CCCCCCCCCCCCCCCCCEECCHHHHHHHHCHHCCHHHHHHHHHHCCCCHHHHHHHHHHHH
VDYYDYSAHNIFDERVEKDIIIGIYRLTMKSNSDNFRQSSIQGIMKRIKAKGVRVVIYEP
HHHCCCCHHHHHHHHHCHHHEEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEECC
TLESGSTFFGSSVINDLEEFKRLSNAIVANRYDNSLEDVKEKVYTRDIFERD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7682279; 11677609 [H]