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The map label for this gene is licC [H]

Identifier: 116515962

GI number: 116515962

Start: 425989

End: 427311

Strand: Direct

Name: licC [H]

Synonym: SPD_0424

Alternate gene names: 116515962

Gene position: 425989-427311 (Clockwise)

Preceding gene: 116517188

Following gene: 116515811

Centisome position: 20.82

GC content: 39.3

Gene sequence:

>1323_bases
ATGAACAATATTTTAGCGTTTTTAGAAACAAAAGTCGCTCCGTTTGGTGAAAAAGTTGGCAACCAACGGCATTTGAAAGC
TATTCGTGAAGGATTTATGATGGCAATGCCTTTGATTTTAGTCGGCTCTTTATTTCTTATTCTAATCAGTTGGCCTCAAG
AGGCTTTTACAAATTGGCTGAATAGTGTTGGATTGCTAAGTATCTTGACAACTATGAATCAGTCAACAGTAGCGATTATC
TCCTTGGTCGCTTGTTTCGGTATTGCCTACAGGTTGTCGGAAGGATATGGTACAGATGGTCCGTCGGCAGGGATCATAGC
CTTATCCAGTTTTGTATTGATGGCACCTCGTTTTTCGAGTATGGTTTATGATAAAAATGGGGAGCAGGTCAAGCAGTTAT
TTGGCGGCGCAATACCATTTTCTAGCCTGAATGCATCTTCTTTGTTTATGGCGATTACTATTGGATTGGTTACAGCAGAG
ATTTATCGTATGTTTATCCAGCGCGGAATTACGATAAAAATGCCAAGTGGTGTCCCAGATGTGGTAAGTAAATCATTTTC
AGCTCTTTTACCTGGCTTTACTACTTTTGTTTTGTGGGCTCTGGTCTTAAAAGGTCTTGAAGCGGCAGGAGTTGCAGGAG
GTCTCAACGGACTCCTAGGTGCAATTGTTGGAACACCGCTTAAGTTAATTGCAGGAACGCTTCCAGGTATGATTCTATGT
GTTATTGTAAACTCATTCTTTTGGTTCTGTGGAGTTAATGGGGGACAAGTTTTAAATGCTTTTGTAGATCCAGTTTGGTT
ACAATTTACTACAGAAAACCAAGAAGCTGTGGCTGCAGGACAAACACTCCAACACATTATTACATTACCGTTTAAAGATT
TATTTGTATTTATTGGTGGCGGTGGAGCGACTATTGGTCTTGCGATTTGTCTCTTCCTATTTAGTAAGAGTCGTGCGAAT
AAAACATTAGGTAAGCTAGCTATTATACCGTCTATTTTTAATATCAATACAGCTATTCTATTTACGTTTCCAACAGTTTT
AAATCCGATTATGCTGATTCCGTTTATTGCTACTCCTACAATCAATGCCTTGATTACCTATGTATCAATGGCTGTAGGAT
TAGTACCCTATACAACAGGTGTAATCCTTCCGTGGACAATGCCACCGATTATAGGAGGCTTCCTTGCAACAGGGGCTAGT
TGGCGAGGAGCTCTATTACAAGTTGTTTTGATTTTGGTTTCTGTAGCAATTTATTATCCATTCTTCAAAATTGCAGATAA
ACGCAATCTTGAAAAAGAAAAAGCTACTGTTGGAGGGAAATAA

Upstream 100 bases:

>100_bases
CAAAGAAAAAAATATTGTAAAAACAACAAAAAATATATTGACAACGCTTTCTGTTAGTGGTATATTTAATTTATAAAAAA
TAAAAAAAGGAGTTCCGGTG

Downstream 100 bases:

>100_bases
GATGGTTATCAGAGTATTTGATCAACAGAAAAATACTTATTCTAGCTTTGCCTTAGAGGAATTAAGTTACTATATGAATC
GGGTCTTTAAGACTAACATA

Product: PTS system, cellobiose-specific IIC component

Products: pyruvate; diacetylchitobiose-6-phosphate [Cytoplasm]; cellobiose-6-phosphate [Cytoplasm] [C]

Alternate protein names: EIIC-Lic; PTS system lichenan-specific EIIC component [H]

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSLFLILISWPQEAFTNWLNSVGLLSILTTMNQSTVAII
SLVACFGIAYRLSEGYGTDGPSAGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGLLGAIVGTPLKLIAGTLPGMILC
VIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEAVAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRAN
KTLGKLAIIPSIFNINTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIGGFLATGAS
WRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK

Sequences:

>Translated_440_residues
MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSLFLILISWPQEAFTNWLNSVGLLSILTTMNQSTVAII
SLVACFGIAYRLSEGYGTDGPSAGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGLLGAIVGTPLKLIAGTLPGMILC
VIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEAVAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRAN
KTLGKLAIIPSIFNINTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIGGFLATGAS
WRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK
>Mature_440_residues
MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSLFLILISWPQEAFTNWLNSVGLLSILTTMNQSTVAII
SLVACFGIAYRLSEGYGTDGPSAGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGLLGAIVGTPLKLIAGTLPGMILC
VIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEAVAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRAN
KTLGKLAIIPSIFNINTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIGGFLATGAS
WRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG1455

COG function: function code G; Phosphotransferase system cellobiose-specific component IIC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=461, Percent_Identity=31.6702819956616, Blast_Score=204, Evalue=9e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: NA

Molecular weight: Translated: 47050; Mature: 47050

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSLFLILISWPQEAFTNWL
CCCHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
NSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPSAGIIALSSFVLMAPRFSS
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHH
MVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAEIYRMFIQRGITIKMPSGVPD
HHCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHH
VVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGLLGAIVGTPLKLIAGTLPGMILC
HHHHHHHHHCCHHHHHHHHHHHHHCCHHHCHHCCHHHHHHHHHCCHHHHHHHHHHHHHHH
VIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEAVAAGQTLQHIITLPFKDLFVFIGG
HHHHHHHHHHCCCHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHCCCHHEEEEECC
GGATIGLAICLFLFSKSRANKTLGKLAIIPSIFNINTAILFTFPTVLNPIMLIPFIATPT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEECHHHHHHHHHHHHHCCCH
INALITYVSMAVGLVPYTTGVILPWTMPPIIGGFLATGASWRGALLQVVLILVSVAIYYP
HHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
FFKIADKRNLEKEKATVGGK
HHHHHHHCCCCHHHHCCCCC
>Mature Secondary Structure
MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSLFLILISWPQEAFTNWL
CCCHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
NSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPSAGIIALSSFVLMAPRFSS
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHH
MVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAEIYRMFIQRGITIKMPSGVPD
HHCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHH
VVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGLLGAIVGTPLKLIAGTLPGMILC
HHHHHHHHHCCHHHHHHHHHHHHHCCHHHCHHCCHHHHHHHHHCCHHHHHHHHHHHHHHH
VIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEAVAAGQTLQHIITLPFKDLFVFIGG
HHHHHHHHHHCCCHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHCCCHHEEEEECC
GGATIGLAICLFLFSKSRANKTLGKLAIIPSIFNINTAILFTFPTVLNPIMLIPFIATPT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEECHHHHHHHHHHHHHCCCH
INALITYVSMAVGLVPYTTGVILPWTMPPIIGGFLATGASWRGALLQVVLILVSVAIYYP
HHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
FFKIADKRNLEKEKATVGGK
HHHHHHHCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: diacetylchitobiose [Periplasm]; phosphoenolpyruvate; cellobiose [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + diacetylchitobiose [Periplasm] = pyruvate + diacetylchitobiose-6-phosphate [Cytoplasm] phosphoenolpyruvate + cellobiose [Periplasm] = cellobiose-6-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8990303; 8969509; 9384377 [H]