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The map label for this gene is polC [H]

Identifier: 116515938

GI number: 116515938

Start: 891532

End: 892122

Strand: Direct

Name: polC [H]

Synonym: SPD_0879

Alternate gene names: 116515938

Gene position: 891532-892122 (Clockwise)

Preceding gene: 116515331

Following gene: 116516500

Centisome position: 43.57

GC content: 39.93

Gene sequence:

>591_bases
ATGGAACGATTAGAAGATTACATTGCTTTTGATTTAGAATTTAATCAGCACGAAGGACAAACACACTTGATTCAAGTATC
GGCAGTGCGTTTTAGAGATGGTCGGGAAATCGATGCCTATGATTCCTATGTTCATACCAGCGTCCCTCTAAAAAGCTTTA
TCAATGGTTTGACCGGGATTACAGCTGAGACCTTAAAAGATGCTCCTCCAGTTGAGAAAGTCTTAGAAGAATTCCAAGAG
TTTGTGGGTTCTTTGCTGATGATAGGCTACAATGCTGCTAAAAGTGATTTACCTATTTTAGCAGAGCATGGTTTAGACTA
TAGCCAACAGTACAAGGTGGATTTGTATGATGAAGCTTTTGAACGTCGGAGTTCAGATTTACATGGTATTGCCAATCTCA
AATTGCAAACTGTTGCCTCATTTCTTGGATTTCAAGGTCAGTCTCATAATAGTTTAGAGGATGCTCGGATGACGGCGCGT
GTTTACGAATCCTTCTTAGAGTCGGATCAAGCTAGGGAATTGTTAGAGACAGAAAGTAGCTTATCAAACAATCCTTTTGG
TGGCTTGGACTTGTCTCAATTATTTGACTAG

Upstream 100 bases:

>100_bases
TAATCAAGGAGCTGTTTAGGTTAAATGCTAACCTGATGGCTTCTTTTGTTTGTGAATAGTATAGTTGATTAGAACAGAGA
CAGTAGAGGAGAGGTACAGA

Downstream 100 bases:

>100_bases
GAGTGCCTATGAAACCTGAAAAACCTAAAAAATTGGGTCTTAAACAGATTTACCTCAATCTTGATAAAATCCTCTTTCTA
TTTTTCTTGATTTTTATGAT

Product: DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: PolIII [H]

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYVHTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQE
FVGSLLMIGYNAAKSDLPILAEHGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD

Sequences:

>Translated_196_residues
MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYVHTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQE
FVGSLLMIGYNAAKSDLPILAEHGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD
>Mature_196_residues
MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYVHTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQE
FVGSLLMIGYNAAKSDLPILAEHGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD

Specific function: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011708
- InterPro:   IPR006054
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR023223
- InterPro:   IPR016027
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR006308
- InterPro:   IPR012337 [H]

Pfam domain/function: PF07733 DNA_pol3_alpha; PF00929 Exonuc_X-T; PF02811 PHP [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 22136; Mature: 22136

Theoretical pI: Translated: 4.23; Mature: 4.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYVHTSVPLKSFINGLTGI
CCHHHHHHEEEEEECCCCCCEEEEEEEEEEECCCCCCCHHHHHHHCCCCHHHHHHHHHCC
TAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAEHGLDYSQQYKVDLYDEAF
HHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCHHCCCCHHHHHH
ERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTARVYESFLESDQARELLETESS
HHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LSNNPFGGLDLSQLFD
CCCCCCCCCCHHHHCC
>Mature Secondary Structure
MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYVHTSVPLKSFINGLTGI
CCHHHHHHEEEEEECCCCCCEEEEEEEEEEECCCCCCCHHHHHHHCCCCHHHHHHHHHCC
TAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAEHGLDYSQQYKVDLYDEAF
HHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCHHCCCCHHHHHH
ERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTARVYESFLESDQARELLETESS
HHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LSNNPFGGLDLSQLFD
CCCCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]