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The map label for this gene is pheA [H]

Identifier: 116515473

GI number: 116515473

Start: 1232551

End: 1233399

Strand: Reverse

Name: pheA [H]

Synonym: SPD_1203

Alternate gene names: 116515473

Gene position: 1233399-1232551 (Counterclockwise)

Preceding gene: 116517070

Following gene: 116516217

Centisome position: 60.28

GC content: 42.64

Gene sequence:

>849_bases
ATGAAAATTGCTTATCTAGGTCCCAAGGGATCATTTTCACACCACGTTGTGCAGACAGCTTTTCCTCATGAGGAATTGCA
GGCTTTTGCCAACATTACAGATGTCATCAAGGCTTATGAGCAAGGATTAGTGAACTATTCTGTGGTGCCAGTTGAAAATT
CTATTGAGGGTAGTGTTCATGAAACCTTGGACTATCTTTTTCATCAGGCTCACATCCAAGCAGTAGCAGAAATCGTTCAG
CCTATTCATCAGCAGTTGATGGTGGTTCCAGGCCATACTAAGATTGAAAAGATTTTTTCACATCCACAGGCCTTGGCTCA
AGGAAAGAAATTCATCGATGAACAATATCCAGAGGCTCAAATCGAGGTAACAGCTAGTACAGCTTATGCGGCCCGTTTTA
TTTCCGAACATCCAGACCAGCCCTTTGCAGCAGTTGCACCTAGAAGTTCTGCTGAAGAATATGGATTGGAACTGATTGCC
GAGGATATTCAGGAAATGGAAGCCAATTTCACACGTTTCTGGGTTCTAGGAGCTGAAAAGCCTAGTATTCCCTTGCAAGC
ACAAACTGAAAAGATGAGTTTGGCCTTGACATTACCTGACAACCTTCCAGGTGCACTTTATAAGGCCCTGTCGACCTTTG
CTTGGCGAGGAATTGACTTGACAAAAATTGAAAGTCGTCCACTCAAGACAGCACTGGGTGAATACTTTTTCATTATCGAT
GTGGATTATACCGATAAGGACTTGGTCCACTTTGCCCAAAAAGAATTAGAAGCGATTGGAATCCAGTATAAAATTCTGGG
TGCCTATCCTATTTATCCAATATCAGACCATGGAAAGGAGAGAAGATGA

Upstream 100 bases:

>100_bases
TAGCTATTTTCCAAGAAAGACAGGCTTGGTATGAGGAAGTGGCTAGTCGGGTTTTGGATGTGACCAAGCTAAGCCCAGAG
GAAATTATAGAGGAACTAAG

Downstream 100 bases:

>100_bases
GTAAAGAAAATCCCTTAAGTCATCATGAGCAGTTGCGTTATGATTATTTGCTAAAAAATATTCACTATCTCAATGAGAGA
GAAAAAAATGAGTTTGCCTA

Product: prephenate dehydratase

Products: NA

Alternate protein names: PDT [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLVNYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQ
PIHQQLMVVPGHTKIEKIFSHPQALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGIDLTKIESRPLKTALGEYFFIID
VDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISDHGKERR

Sequences:

>Translated_282_residues
MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLVNYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQ
PIHQQLMVVPGHTKIEKIFSHPQALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGIDLTKIESRPLKTALGEYFFIID
VDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISDHGKERR
>Mature_282_residues
MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLVNYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQ
PIHQQLMVVPGHTKIEKIFSHPQALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGIDLTKIESRPLKTALGEYFFIID
VDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISDHGKERR

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=276, Percent_Identity=31.5217391304348, Blast_Score=120, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF00800 PDT [H]

EC number: =4.2.1.51 [H]

Molecular weight: Translated: 31650; Mature: 31650

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLVNYSVVPVENSIEGSVH
CEEEEECCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHH
ETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHPQALAQGKKFIDEQYPEAQ
HHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCHHHHHHHCCHHHHHHHHHHHHHCCCCCE
IEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIAEDIQEMEANFTRFWVLGAEK
EEEEEHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCC
PSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGIDLTKIESRPLKTALGEYFFIID
CCCCCEECCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEECCCCCHHHHHCCEEEEEE
VDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISDHGKERR
ECCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLVNYSVVPVENSIEGSVH
CEEEEECCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHH
ETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHPQALAQGKKFIDEQYPEAQ
HHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCHHHHHHHCCHHHHHHHHHHHHHCCCCCE
IEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIAEDIQEMEANFTRFWVLGAEK
EEEEEHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCC
PSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGIDLTKIESRPLKTALGEYFFIID
CCCCCEECCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEECCCCCHHHHHCCEEEEEE
VDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISDHGKERR
ECCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]