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The map label for this gene is murM/fibA [H]

Identifier: 116515318

GI number: 116515318

Start: 547849

End: 549069

Strand: Direct

Name: murM/fibA [H]

Synonym: SPD_0535

Alternate gene names: 116515318

Gene position: 547849-549069 (Clockwise)

Preceding gene: 116516440

Following gene: 116515311

Centisome position: 26.78

GC content: 36.94

Gene sequence:

>1221_bases
ATGTACCGTTATCAAATTGGCATTCCCACATTAGAATATGATCAGTTTGTCAAAGAACATGAATTAGCCAATGTATTACA
AAGTAGTGCTTGGGAGGAAGTTAAGTCTAATTGGCAACATGAGAAGTTTGGTGTTTACAGGGAAGAAAAATTACTGGCGA
CAGCTAGTATTTTGATTAGAACTCTTCCGCTAGGCTATAAAATGTTTTACATCCCAAGAGGACCTATATTGGATTATGGG
GATAAAGAACTCTTGAATTTTGCCATTCAGTCTATTAAGTCCTATGCTCGCAGTAAGAGAGTGGTTTTTGTGACTTTTGA
CCCAAGTATTTGCCTATCTCAAAGTTTAATCAATCAGGAAAAGACAGAATTTCCTGAAAATCTGGCTATTATTGATAGTT
TGCAACAAATGGGAGTAAGGTGGTCAGGAAAAACGGAGGAAATGGGAGACACCATTCAACCTCGTATTCAGGCGAAAATA
TACAAGGAAAATTTTGAAGAAGATAAACTTTCCAAGTCAACAAAACAGGCTATTCGAACAGCACGAAACAAAGGGCTTGA
GATTCAATATGGTGGACTGGAACTATTAGATTCATTTTCGGAGTTGATGAAAAAAACTGAGAAGCGAAAAGAGATTCATT
TGAGGAATGAAGCCTATTATAAAAAATTGTTAGATAATTTTAAGGACAAGGCCTATATCACCTTGGCCACCTTGGATGTT
TCTAAACGTTCGCAAGAATTAGAAGAACAGTTAGCGAAAAATAGAGCCTTGGAAGAGACCTTTACTGAGTCGACTCGAAC
TTCAAAAGTAGAAGCGCAGAAGAAGGAAAAAGAACGTTTGTTAGAGGAATTGACCTTCTTGCAGGAATATATAGATGTAG
GTCAAGCGAGAGTTCCTTTAGCGGCTACTTTGAGTTTGGAATTTGGTACTACCTCTGTCAATATATATGCTGGTATGGAT
GATGATTTTAAACGTTACAATGCACCAATTTTAACATGGTATGAAACGGCTCGCTATGCCTTTGAGCGAGGTATGGTCTG
GCAAAATTTAGGTGGTGTTGAAAACTCTCTCAATGGTGGACTTTATCATTTTAAGGAAAAATTTAATCCAACGATTGAAG
AATACTTGGGTGAATTTACAATGCCCACTCATCCTCTCTATCCTCTGTTAAGACTTGCTCTTGATTTCCGTAAAACATTA
AGAAAAAAACATAGAAAGTAA

Upstream 100 bases:

>100_bases
GCATAGGGGGAGTAGAACTAAAATAAAATATGTTTTCACTAGACTTTTCAAACGAAAGTAGTAGAATAGTAATAAAATAC
TGGAGGAAAGAGAGTAGGAA

Downstream 100 bases:

>100_bases
GTATATGGCACTAACAACACTCACGAAAGAAGAGTTTCAGACTTATTCTGATCAGGTTTCTTCTCGTTCCTTTATGCAAT
CTGTCCAGATGGGGGATTTG

Product: serine/alanine-adding enzyme MurM

Products: NA

Alternate protein names: Factor essential for expression of methicillin resistance X [H]

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFGVYREEKLLATASILIRTLPLGYKMFYIPRGPILDYG
DKELLNFAIQSIKSYARSKRVVFVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEAYYKKLLDNFKDKAYITLATLDV
SKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKEKERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMD
DDFKRYNAPILTWYETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRLALDFRKTL
RKKHRK

Sequences:

>Translated_406_residues
MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFGVYREEKLLATASILIRTLPLGYKMFYIPRGPILDYG
DKELLNFAIQSIKSYARSKRVVFVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEAYYKKLLDNFKDKAYITLATLDV
SKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKEKERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMD
DDFKRYNAPILTWYETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRLALDFRKTL
RKKHRK
>Mature_406_residues
MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFGVYREEKLLATASILIRTLPLGYKMFYIPRGPILDYG
DKELLNFAIQSIKSYARSKRVVFVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEAYYKKLLDNFKDKAYITLATLDV
SKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKEKERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMD
DDFKRYNAPILTWYETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRLALDFRKTL
RKKHRK

Specific function: Catalyzes the incorporation of the first glycine of the pentaglycine interpeptide bridge, which is characteristic of the S.aureus peptidoglycan. This glycine is added to the epsilon-amino group of the L-lysine of the membrane-bound lipid II intermediate (

COG id: COG2348

COG function: function code V; Uncharacterized protein involved in methicillin resistance

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the femABX family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016181
- InterPro:   IPR003447 [H]

Pfam domain/function: PF02388 FemAB [H]

EC number: NA

Molecular weight: Translated: 47442; Mature: 47442

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFGVYREEKLLATASILIR
CCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHH
TLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRVVFVTFDPSICLSQSLINQE
HHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHH
KTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKIYKENFEEDKLSKSTKQAIRT
HHCCCCHHHHHHHHHHCCCCCCCCCHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
ARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEAYYKKLLDNFKDKAYITLATLDV
HHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECH
SKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKEKERLLEELTFLQEYIDVGQARVPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
AATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWYETARYAFERGMVWQNLGGVENSLNGG
EEEEEEEECCCEEEEEECCCHHHHHHCCCEEEHHHHHHHHHHHCCHHHHCCCCCCCCCCC
LYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRLALDFRKTLRKKHRK
HHHHHHHCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFGVYREEKLLATASILIR
CCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHH
TLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRVVFVTFDPSICLSQSLINQE
HHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHH
KTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKIYKENFEEDKLSKSTKQAIRT
HHCCCCHHHHHHHHHHCCCCCCCCCHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
ARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEAYYKKLLDNFKDKAYITLATLDV
HHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECH
SKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKEKERLLEELTFLQEYIDVGQARVPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
AATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWYETARYAFERGMVWQNLGGVENSLNGG
EEEEEEEECCCEEEEEECCCHHHHHHCCCEEEHHHHHHHHHHHCCHHHHCCCCCCCCCCC
LYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRLALDFRKTLRKKHRK
HHHHHHHCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA