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The map label for this gene is fibB [H]

Identifier: 116515311

GI number: 116515311

Start: 549074

End: 550306

Strand: Direct

Name: fibB [H]

Synonym: SPD_0536

Alternate gene names: 116515311

Gene position: 549074-550306 (Clockwise)

Preceding gene: 116515318

Following gene: 116516355

Centisome position: 26.83

GC content: 35.28

Gene sequence:

>1233_bases
ATGGCACTAACAACACTCACGAAAGAAGAGTTTCAGACTTATTCTGATCAGGTTTCTTCTCGTTCCTTTATGCAATCTGT
CCAGATGGGGGATTTGCTAGAAAAAAGAGGGGCTCGAATTGTTTATCTTGCTTTGAAACAAGAAGGAGAAATTCAAGTTG
CAGCTCTGGTTTATAGCTTGCCCATGCTGGGTGGTCTGCATATGGAACTCAATTCGGGGCCGATTTATACCCAACAAGAT
GCTCTTCCAGTTTTTTATGCAGAGTTAAAAGAATATGCCAAGCAAAATGGTGTATTAGAGTTGCTTGTAAAACCTTATGA
AACTTATCAAACTTTTGATAGCCAAGGTAATCCAATAGATGCTGAGAAAAAAAGTATTATTCAAGGTTTGACTGATTTAG
GTTATCAATTTGATGGCTTAACAACAGGTTACCCAGGTGGAGAACCAGATTGGTTATACTATAAAGATTTAACTGAATTA
ACTGAAAAGAGTTTGCTTAAAAGTTTTAGCAAAAAGGGTAAACCCTTGGTGAAAAAGGCTGAAACCTTTGGCATTCGGTT
GAAAAAGTTAAAACGTGAAGAACTATCGATTTTTAAGAATATAACAAAAGAAACCTCTGAACGTAGAGAATATAGTGATA
AAAGTTTAGAATATTATGAGCATTTTTATGATACTTTTGGAGAACAAGCGGAGTTTCTCATAGCAAGCTTAAATTTTTCG
GACTATATGAGCAAATTGCAAGGTGAACAAAGTAAACTAGAAGAAAACTTGGACAAGTTGCGACTTGATTTGAGTAAAAA
TCCTCATTCTGAGAAAAAACAAAATCAACTGAGAGAATATTCTAGTCAATTTGAAACGTTTGAAGTTCGAAAAGCAGAAG
CGCGAGACTTGATTGAAAAATATGGAGAAGAAGATATTGTTTTAGCTGGGAGTTTATTTGTTTATATGCCTCAGGAAACG
ACTTATCTCTTTAGTGGTTCCTACACTGAGTTTAATAAGTTCTATGCCCCTGCCCTGCTTCAAAAATATGTTATGTTGGA
AAGCATAAAACGTGGAATACCTAAATACAACTTCCTAGGCATTCAAGGGATTTTTGATGGAAGTGATGGTGTTTTGCGTT
TTAAACAGAATTTTAATGGCTATATTGTACGCAAAGCAGGTACTTTCCGTTACCATCCATCTCCTTTAAAATACAAAGCT
ATCCAGTTACTCAAAAAAATAGTAGGACGTTAA

Upstream 100 bases:

>100_bases
TTGGGTGAATTTACAATGCCCACTCATCCTCTCTATCCTCTGTTAAGACTTGCTCTTGATTTCCGTAAAACATTAAGAAA
AAAACATAGAAAGTAAGTAT

Downstream 100 bases:

>100_bases
GATGAAAAAGTCAGTATTTAGATTTCTTTTAGCTTCTTTTAGTAAAATAATTCTTATTTGCTAGAAAGGTGGAGAGACAT
GCGCTGGCTTTTTCGTTTGA

Product: beta-lactam resistance factor

Products: NA

Alternate protein names: Factor essential for expression of methicillin resistance A [H]

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLALKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQD
ALPVFYAELKEYAKQNGVLELLVKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEYYEHFYDTFGEQAEFLIASLNFS
DYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQLREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQET
TYLFSGSYTEFNKFYAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYHPSPLKYKA
IQLLKKIVGR

Sequences:

>Translated_410_residues
MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLALKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQD
ALPVFYAELKEYAKQNGVLELLVKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEYYEHFYDTFGEQAEFLIASLNFS
DYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQLREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQET
TYLFSGSYTEFNKFYAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYHPSPLKYKA
IQLLKKIVGR
>Mature_409_residues
ALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLALKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDA
LPVFYAELKEYAKQNGVLELLVKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTELT
EKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEYYEHFYDTFGEQAEFLIASLNFSD
YMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQLREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETT
YLFSGSYTEFNKFYAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYHPSPLKYKAI
QLLKKIVGR

Specific function: Catalyzes the formation of the pentaglycine interpeptide bridge, which is characteristic of the S.aureus peptidoglycan. Adds glycines 2 and 3 of the pentaglycine bridge, using glycyl- tRNA(Gly) as donor. Involved in resistance to methicillin [H]

COG id: COG2348

COG function: function code V; Uncharacterized protein involved in methicillin resistance

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the femABX family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016181
- InterPro:   IPR003447
- InterPro:   IPR010978 [H]

Pfam domain/function: PF02388 FemAB [H]

EC number: NA

Molecular weight: Translated: 47300; Mature: 47168

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLALKQEGEIQVAALVYSL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEHHHHHHHH
PMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELLVKPYETYQTFDSQGNPID
HHHCCEEEEECCCCCEECCCCCHHHHHHHHHHHHHCCEEEEHHCCHHHHHHHCCCCCCCC
AEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTELTEKSLLKSFSKKGKPLVKKA
HHHHHHHHHHHHCCEEECCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCHHHHHH
ETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEYYEHFYDTFGEQAEFLIASLNFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHEEEECCHH
DYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQLREYSSQFETFEVRKAEARDLIEK
HHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKFYAPALLQKYVMLESIKRGIPKYNFLG
HCCCCEEEECEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
IQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYHPSPLKYKAIQLLKKIVGR
EEEEEECCCCEEEEEECCCEEEEEECCCEEECCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
ALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLALKQEGEIQVAALVYSL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEHHHHHHHH
PMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELLVKPYETYQTFDSQGNPID
HHHCCEEEEECCCCCEECCCCCHHHHHHHHHHHHHCCEEEEHHCCHHHHHHHCCCCCCCC
AEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTELTEKSLLKSFSKKGKPLVKKA
HHHHHHHHHHHHCCEEECCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCHHHHHH
ETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEYYEHFYDTFGEQAEFLIASLNFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHEEEECCHH
DYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQLREYSSQFETFEVRKAEARDLIEK
HHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKFYAPALLQKYVMLESIKRGIPKYNFLG
HCCCCEEEECEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
IQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYHPSPLKYKAIQLLKKIVGR
EEEEEECCCCEEEEEECCCEEEEEECCCEEECCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA