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The map label for this gene is pgi

Identifier: 116515287

GI number: 116515287

Start: 392364

End: 394004

Strand: Reverse

Name: pgi

Synonym: BCc_372

Alternate gene names: 116515287

Gene position: 394004-392364 (Counterclockwise)

Preceding gene: 116515289

Following gene: 116515286

Centisome position: 94.63

GC content: 21.69

Gene sequence:

>1641_bases
ATGAAAAATATTAATCCTATGAAAACACATGCATGGAAAAAATTACAAAATCATTTTTTTGATGTTAAAAATATTTATAT
AAAAGATTTTTTTTGTTTAGATAAAAATAGATTTGCAAATTTTTCTGTTTTTTTTAAAGATTTTATGTTAATAGATTTTT
CGAAAAATAGAATTTCTTCTCAAACATTAAAACTTTTGTTTCAATTAGCCCAAGAATGTTATTTAGATGATGCTATAAAA
AATATGTTTTTAGGAAAAATAATTAATAAAACAGAAAATCGTCCAGTTTTACATGTAGCTTTACGTAATCGATTAAATAA
TAAAATTATTTTAAATAATATTGATATTATGAATGAAATTCAAATAGAATTAAAAAAGATAAAATGTTTTTCTGAATCAA
TCATTGATGGATCTTGGAAAGGTTTTACTGGAAAATCTATTTCTGACGTAGTTAATATTGGAATAGGTGGTTCTTATTTA
GGTCCTTATATGATTACTGAAGCATTAAAAATTTATAAAAATCATTTAAATATTCATTATATTTCGAATATAGATGGTAC
AGAAATTTCTGAAGTATTAAAAAAAATTAATTTAGAAACTACTATATTTTTAATAGCTTCTAAATCTTTTTCCACAGATG
AAACAATTAGTAATGCAAATTATTTAAAAAAATGGTGTATTTTAAAAACAAATTATAAAAAATATTTTTCTAAACATTTT
TTTGCTTTATGTGAAAATATAAAAACTGCTATAAATTTTGGGATAAAATATGAAAATATTTTTAAATTTTGGGATTGGGT
AGGTGGTCGATATTCTTTATGGTCTTCTTCCGGATTATCTATTGTTTTATCAATAGGTTTTAAGAATTTTGAATCATTAT
TATACGGCGCATATTTAATGGATCAACATTTTTTACATACAAAGATTTCTAAAAATATTCCTATTATATTAGCTTTAATT
AGTATTTGGTATACTAATTTTTTTAATACAGAAACAGAGGCTATATTTCCGTATGATAAATATTTGCATGTTTTACCAGA
ATATTTACAACAAAGTTATATGGAATCTAATGGTAAATCTATTGATCGTAATGGAAAATTAGTTACTTGGAATACTTGTC
CTATCATTTGGGGTAGTACAGGTACTAATGGACAACATTCATTTTTTCAGCTTTTACATCAAGGAACTACAATGGTTCCA
TGTGATTTTATAATTCCAGCAATTAGTCATAATTTGATTAATGATCATCATAAAAAACTATTATCAAATTTCTTAGCACA
AACAGCTTCTTTAGCATTTGGAAATATTAATAAAGATATTATGAATATGAATTTAAAATATTCTTCAGAAAATTTTATTT
TTTCTCATAAAACTTATTTTGGCAACAAACCTAGTAATTCAATTTTTTTAAAAAAAATTACTCCTATTTCTTTAGGGTCT
TTAATAGCTTTATATGAACATAAAATTTTTGTTCAAGGTGTTATTTTAAATATTTTTAGTTTTGATCAATGGGGAGTAGA
ATTAGGAAAAACTGTAGCAAATAATATTTATAATAATTTATTTAAAAAAAAAAAAATAAATGTTTATGATTGTTCTACTA
TAGGTTTGATTAATTTATATAAATATTGGAATAGAATTTAA

Upstream 100 bases:

>100_bases
AATTAATTATTTTATTTAATAAATATAAAAAATTTTTATATTTATTATATATGAAGTTTAGTTAGTTGTAAAAATAATTT
AAAACTAAGAGAGGTAGATT

Downstream 100 bases:

>100_bases
TTCTATAATTATTTTATAATATATAATATATAATAATTATTAATTAATAATATTTTTTAAATTAATAAAATATTAATTAA
TAATTAAATTTTAATTAAAT

Product: Pgi

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI

Number of amino acids: Translated: 546; Mature: 546

Protein sequence:

>546_residues
MKNINPMKTHAWKKLQNHFFDVKNIYIKDFFCLDKNRFANFSVFFKDFMLIDFSKNRISSQTLKLLFQLAQECYLDDAIK
NMFLGKIINKTENRPVLHVALRNRLNNKIILNNIDIMNEIQIELKKIKCFSESIIDGSWKGFTGKSISDVVNIGIGGSYL
GPYMITEALKIYKNHLNIHYISNIDGTEISEVLKKINLETTIFLIASKSFSTDETISNANYLKKWCILKTNYKKYFSKHF
FALCENIKTAINFGIKYENIFKFWDWVGGRYSLWSSSGLSIVLSIGFKNFESLLYGAYLMDQHFLHTKISKNIPIILALI
SIWYTNFFNTETEAIFPYDKYLHVLPEYLQQSYMESNGKSIDRNGKLVTWNTCPIIWGSTGTNGQHSFFQLLHQGTTMVP
CDFIIPAISHNLINDHHKKLLSNFLAQTASLAFGNINKDIMNMNLKYSSENFIFSHKTYFGNKPSNSIFLKKITPISLGS
LIALYEHKIFVQGVILNIFSFDQWGVELGKTVANNIYNNLFKKKKINVYDCSTIGLINLYKYWNRI

Sequences:

>Translated_546_residues
MKNINPMKTHAWKKLQNHFFDVKNIYIKDFFCLDKNRFANFSVFFKDFMLIDFSKNRISSQTLKLLFQLAQECYLDDAIK
NMFLGKIINKTENRPVLHVALRNRLNNKIILNNIDIMNEIQIELKKIKCFSESIIDGSWKGFTGKSISDVVNIGIGGSYL
GPYMITEALKIYKNHLNIHYISNIDGTEISEVLKKINLETTIFLIASKSFSTDETISNANYLKKWCILKTNYKKYFSKHF
FALCENIKTAINFGIKYENIFKFWDWVGGRYSLWSSSGLSIVLSIGFKNFESLLYGAYLMDQHFLHTKISKNIPIILALI
SIWYTNFFNTETEAIFPYDKYLHVLPEYLQQSYMESNGKSIDRNGKLVTWNTCPIIWGSTGTNGQHSFFQLLHQGTTMVP
CDFIIPAISHNLINDHHKKLLSNFLAQTASLAFGNINKDIMNMNLKYSSENFIFSHKTYFGNKPSNSIFLKKITPISLGS
LIALYEHKIFVQGVILNIFSFDQWGVELGKTVANNIYNNLFKKKKINVYDCSTIGLINLYKYWNRI
>Mature_546_residues
MKNINPMKTHAWKKLQNHFFDVKNIYIKDFFCLDKNRFANFSVFFKDFMLIDFSKNRISSQTLKLLFQLAQECYLDDAIK
NMFLGKIINKTENRPVLHVALRNRLNNKIILNNIDIMNEIQIELKKIKCFSESIIDGSWKGFTGKSISDVVNIGIGGSYL
GPYMITEALKIYKNHLNIHYISNIDGTEISEVLKKINLETTIFLIASKSFSTDETISNANYLKKWCILKTNYKKYFSKHF
FALCENIKTAINFGIKYENIFKFWDWVGGRYSLWSSSGLSIVLSIGFKNFESLLYGAYLMDQHFLHTKISKNIPIILALI
SIWYTNFFNTETEAIFPYDKYLHVLPEYLQQSYMESNGKSIDRNGKLVTWNTCPIIWGSTGTNGQHSFFQLLHQGTTMVP
CDFIIPAISHNLINDHHKKLLSNFLAQTASLAFGNINKDIMNMNLKYSSENFIFSHKTYFGNKPSNSIFLKKITPISLGS
LIALYEHKIFVQGVILNIFSFDQWGVELGKTVANNIYNNLFKKKKINVYDCSTIGLINLYKYWNRI

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family

Homologues:

Organism=Homo sapiens, GI18201905, Length=540, Percent_Identity=48.1481481481481, Blast_Score=527, Evalue=1e-150,
Organism=Homo sapiens, GI296080693, Length=540, Percent_Identity=44.8148148148148, Blast_Score=473, Evalue=1e-133,
Organism=Escherichia coli, GI1790457, Length=547, Percent_Identity=59.2321755027422, Blast_Score=696, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71996703, Length=529, Percent_Identity=49.5274102079395, Blast_Score=535, Evalue=1e-152,
Organism=Caenorhabditis elegans, GI71996708, Length=529, Percent_Identity=49.5274102079395, Blast_Score=535, Evalue=1e-152,
Organism=Saccharomyces cerevisiae, GI6319673, Length=541, Percent_Identity=47.6894639556377, Blast_Score=504, Evalue=1e-143,
Organism=Drosophila melanogaster, GI24651916, Length=542, Percent_Identity=51.1070110701107, Blast_Score=559, Evalue=1e-159,
Organism=Drosophila melanogaster, GI24651914, Length=542, Percent_Identity=51.1070110701107, Blast_Score=559, Evalue=1e-159,
Organism=Drosophila melanogaster, GI17737445, Length=542, Percent_Identity=51.1070110701107, Blast_Score=559, Evalue=1e-159,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): G6PI_BUCCC (Q056X6)

Other databases:

- EMBL:   CP000263
- RefSeq:   YP_802916.1
- ProteinModelPortal:   Q056X6
- SMR:   Q056X6
- STRING:   Q056X6
- EnsemblBacteria:   EBBUCT00000001440
- GeneID:   4440963
- GenomeReviews:   CP000263_GR
- KEGG:   bcc:BCc_372
- eggNOG:   COG0166
- GeneTree:   EBGT00050000008090
- HOGENOM:   HBG352954
- OMA:   GPKIVSQ
- BioCyc:   BAPH372461:BCC_372-MONOMER
- GO:   GO:0005737
- GO:   GO:0006094
- GO:   GO:0006096
- HAMAP:   MF_00473
- InterPro:   IPR001672
- InterPro:   IPR023096
- InterPro:   IPR018189
- Gene3D:   G3DSA:1.10.1390.10
- PANTHER:   PTHR11469
- PRINTS:   PR00662

Pfam domain/function: PF00342 PGI

EC number: =5.3.1.9

Molecular weight: Translated: 63296; Mature: 63296

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1; PS00174 P_GLUCOSE_ISOMERASE_2; PS51463 P_GLUCOSE_ISOMERASE_3

Important sites: ACT_SITE 355-355 ACT_SITE 386-386 ACT_SITE 510-510

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNINPMKTHAWKKLQNHFFDVKNIYIKDFFCLDKNRFANFSVFFKDFMLIDFSKNRISS
CCCCCCHHHHHHHHHHHHHCCHHHEEEEEEEEECCCCCCCHHHEEEEEEEEECCCHHHHH
QTLKLLFQLAQECYLDDAIKNMFLGKIINKTENRPVLHVALRNRLNNKIILNNIDIMNEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHCCCEEEEECCCHHHHH
QIELKKIKCFSESIIDGSWKGFTGKSISDVVNIGIGGSYLGPYMITEALKIYKNHLNIHY
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEE
ISNIDGTEISEVLKKINLETTIFLIASKSFSTDETISNANYLKKWCILKTNYKKYFSKHF
ECCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCHHHCCHHHHHHHHEEECCHHHHHHHHH
FALCENIKTAINFGIKYENIFKFWDWVGGRYSLWSSSGLSIVLSIGFKNFESLLYGAYLM
HHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCEEEEEECHHHHHHHHHHHHHH
DQHFLHTKISKNIPIILALISIWYTNFFNTETEAIFPYDKYLHVLPEYLQQSYMESNGKS
HHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEECCHHHHHHHHHHHHHHHHHHCCCCE
IDRNGKLVTWNTCPIIWGSTGTNGQHSFFQLLHQGTTMVPCDFIIPAISHNLINDHHKKL
ECCCCCEEEEECCEEEECCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
LSNFLAQTASLAFGNINKDIMNMNLKYSSENFIFSHKTYFGNKPSNSIFLKKITPISLGS
HHHHHHHHHHHHCCCCCHHHHEEEEEECCCCEEEEECEECCCCCCCCEEEEEECCCCHHH
LIALYEHKIFVQGVILNIFSFDQWGVELGKTVANNIYNNLFKKKKINVYDCSTIGLINLY
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHH
KYWNRI
HHHHCC
>Mature Secondary Structure
MKNINPMKTHAWKKLQNHFFDVKNIYIKDFFCLDKNRFANFSVFFKDFMLIDFSKNRISS
CCCCCCHHHHHHHHHHHHHCCHHHEEEEEEEEECCCCCCCHHHEEEEEEEEECCCHHHHH
QTLKLLFQLAQECYLDDAIKNMFLGKIINKTENRPVLHVALRNRLNNKIILNNIDIMNEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHCCCEEEEECCCHHHHH
QIELKKIKCFSESIIDGSWKGFTGKSISDVVNIGIGGSYLGPYMITEALKIYKNHLNIHY
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEE
ISNIDGTEISEVLKKINLETTIFLIASKSFSTDETISNANYLKKWCILKTNYKKYFSKHF
ECCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCHHHCCHHHHHHHHEEECCHHHHHHHHH
FALCENIKTAINFGIKYENIFKFWDWVGGRYSLWSSSGLSIVLSIGFKNFESLLYGAYLM
HHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCEEEEEECHHHHHHHHHHHHHH
DQHFLHTKISKNIPIILALISIWYTNFFNTETEAIFPYDKYLHVLPEYLQQSYMESNGKS
HHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEECCHHHHHHHHHHHHHHHHHHCCCCE
IDRNGKLVTWNTCPIIWGSTGTNGQHSFFQLLHQGTTMVPCDFIIPAISHNLINDHHKKL
ECCCCCEEEEECCEEEECCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
LSNFLAQTASLAFGNINKDIMNMNLKYSSENFIFSHKTYFGNKPSNSIFLKKITPISLGS
HHHHHHHHHHHHCCCCCHHHHEEEEEECCCCEEEEECEECCCCCCCCEEEEEECCCCHHH
LIALYEHKIFVQGVILNIFSFDQWGVELGKTVANNIYNNLFKKKKINVYDCSTIGLINLY
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHH
KYWNRI
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA