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The map label for this gene is aroE

Identifier: 116515230

GI number: 116515230

Start: 353033

End: 353875

Strand: Reverse

Name: aroE

Synonym: BCc_312

Alternate gene names: 116515230

Gene position: 353875-353033 (Counterclockwise)

Preceding gene: 116515233

Following gene: 116515229

Centisome position: 84.99

GC content: 19.93

Gene sequence:

>843_bases
ATGCAAAATAGTAAATATTGTGAAAAAAAAATTCATATTGCTTTGTTCGGAAATCCCATAGAGCATTCTTTATCTCCATT
AATACATAAAAATTTTTCTAAAGAGATAAAAATTAATTATAATTATAACTCTTTTTTATGTACAAAATCAAATTTTTTTG
TTATAGTAAAAAATTTTTTTCAAAATGGTGGTTTTGGATGCAACATTACTGTTCCTTTTAAAAAAAAATCATTTCAAATT
TCAAATAAAAATACTAAATATGTAAAAATTTCTAATTCGGTAAATGTTTTAAAAAAAAGTTCAAATAATAATATTATTGG
TTACAACACGGATGGAATTGGATTAATTTATGATTTAAATCGTTTAAAATATATCACAGAAAATTCTTTTATTTTAATAT
TAGGTTCAGGTGGAGCTGTATATTCTATTGTATATCATTTATTAAAAAAAAAATGTTGTATTTTTATTTTAAATCGAACA
ATTAGTAAATCATGTATTTTAGTAAATAAATTTAAAAAATTTGGAAAAATTTTTGTTTTTGATAAAAATTTATATACAAA
AAAATTTGATATTATTATTAATGCCACTTCATGCGGGTTATATAATTTCTCTCCTAAATTTCCAAAAAATTTGATATTTC
CAAATACAAAATGTTATGATATTTCTTATTCAAAAAATAAAAAATTAACCCCTTTTTTATCTACTTGTAGAGATTTAGGT
AGTAGAAAATATTCTGATGGCTTAGGAATGTTAGTAGCACAAGCAGCATATTCATGTTATATATGGTTTAACATACTACC
AAACATTAAAAAAAATATTAATTTATTAAAATCTATTATATAA

Upstream 100 bases:

>100_bases
AATTTACCAGAATATTTAATTAACTATTTATTAATATAAATATAATAATTTTTTTTTATATTATTGTTTTTGATTTTATT
AAAATTTTTAGGAATTTAAA

Downstream 100 bases:

>100_bases
ATGTTTTTTTATTTCAAATAATTTAAATATTTTTTTATATAAAAAAATATCTATTAAAAATATAATAAAAAAACTTGACT
CTTTTTGTGTATTCTGTATT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MQNSKYCEKKIHIALFGNPIEHSLSPLIHKNFSKEIKINYNYNSFLCTKSNFFVIVKNFFQNGGFGCNITVPFKKKSFQI
SNKNTKYVKISNSVNVLKKSSNNNIIGYNTDGIGLIYDLNRLKYITENSFILILGSGGAVYSIVYHLLKKKCCIFILNRT
ISKSCILVNKFKKFGKIFVFDKNLYTKKFDIIINATSCGLYNFSPKFPKNLIFPNTKCYDISYSKNKKLTPFLSTCRDLG
SRKYSDGLGMLVAQAAYSCYIWFNILPNIKKNINLLKSII

Sequences:

>Translated_280_residues
MQNSKYCEKKIHIALFGNPIEHSLSPLIHKNFSKEIKINYNYNSFLCTKSNFFVIVKNFFQNGGFGCNITVPFKKKSFQI
SNKNTKYVKISNSVNVLKKSSNNNIIGYNTDGIGLIYDLNRLKYITENSFILILGSGGAVYSIVYHLLKKKCCIFILNRT
ISKSCILVNKFKKFGKIFVFDKNLYTKKFDIIINATSCGLYNFSPKFPKNLIFPNTKCYDISYSKNKKLTPFLSTCRDLG
SRKYSDGLGMLVAQAAYSCYIWFNILPNIKKNINLLKSII
>Mature_280_residues
MQNSKYCEKKIHIALFGNPIEHSLSPLIHKNFSKEIKINYNYNSFLCTKSNFFVIVKNFFQNGGFGCNITVPFKKKSFQI
SNKNTKYVKISNSVNVLKKSSNNNIIGYNTDGIGLIYDLNRLKYITENSFILILGSGGAVYSIVYHLLKKKCCIFILNRT
ISKSCILVNKFKKFGKIFVFDKNLYTKKFDIIINATSCGLYNFSPKFPKNLIFPNTKCYDISYSKNKKLTPFLSTCRDLG
SRKYSDGLGMLVAQAAYSCYIWFNILPNIKKNINLLKSII

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family

Homologues:

Organism=Escherichia coli, GI1789675, Length=266, Percent_Identity=40.2255639097744, Blast_Score=228, Evalue=4e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROE_BUCCC (Q057D3)

Other databases:

- EMBL:   CP000263
- RefSeq:   YP_802859.1
- ProteinModelPortal:   Q057D3
- SMR:   Q057D3
- STRING:   Q057D3
- EnsemblBacteria:   EBBUCT00000001300
- GeneID:   4440670
- GenomeReviews:   CP000263_GR
- KEGG:   bcc:BCc_312
- eggNOG:   COG0169
- GeneTree:   EBGT00050000008051
- HOGENOM:   HBG553408
- OMA:   DQYVVFG
- BioCyc:   BAPH372461:BCC_312-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00222
- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151
- Gene3D:   G3DSA:3.40.50.720
- TIGRFAMs:   TIGR00507

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N

EC number: =1.1.1.25

Molecular weight: Translated: 32079; Mature: 32079

Theoretical pI: Translated: 10.35; Mature: 10.35

Prosite motif: NA

Important sites: ACT_SITE 74-74

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNSKYCEKKIHIALFGNPIEHSLSPLIHKNFSKEIKINYNYNSFLCTKSNFFVIVKNFF
CCCCCCCCEEEEEEEECCCHHHHHHHHHHCCCCCEEEEEECCCEEEEECCCEEEEEEHHH
QNGGFGCNITVPFKKKSFQISNKNTKYVKISNSVNVLKKSSNNNIIGYNTDGIGLIYDLN
HCCCCEEEEEECCCCCEEEECCCCEEEEEECCCEEEEEECCCCCEEEECCCCEEEEEECC
RLKYITENSFILILGSGGAVYSIVYHLLKKKCCIFILNRTISKSCILVNKFKKFGKIFVF
CEEEEECCCEEEEEECCCHHHHHHHHHHHHHHEEEEEECCCCCCEEEHHHHHHCCEEEEE
DKNLYTKKFDIIINATSCGLYNFSPKFPKNLIFPNTKCYDISYSKNKKLTPFLSTCRDLG
ECCCCEEEEEEEEEEEECCEECCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHC
SRKYSDGLGMLVAQAAYSCYIWFNILPNIKKNINLLKSII
CCCCCCCHHHHHHHHHHEEEEEEEECCCHHHHHHHHHHCC
>Mature Secondary Structure
MQNSKYCEKKIHIALFGNPIEHSLSPLIHKNFSKEIKINYNYNSFLCTKSNFFVIVKNFF
CCCCCCCCEEEEEEEECCCHHHHHHHHHHCCCCCEEEEEECCCEEEEECCCEEEEEEHHH
QNGGFGCNITVPFKKKSFQISNKNTKYVKISNSVNVLKKSSNNNIIGYNTDGIGLIYDLN
HCCCCEEEEEECCCCCEEEECCCCEEEEEECCCEEEEEECCCCCEEEECCCCEEEEEECC
RLKYITENSFILILGSGGAVYSIVYHLLKKKCCIFILNRTISKSCILVNKFKKFGKIFVF
CEEEEECCCEEEEEECCCHHHHHHHHHHHHHHEEEEEECCCCCCEEEHHHHHHCCEEEEE
DKNLYTKKFDIIINATSCGLYNFSPKFPKNLIFPNTKCYDISYSKNKKLTPFLSTCRDLG
ECCCCEEEEEEEEEEEECCEECCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHC
SRKYSDGLGMLVAQAAYSCYIWFNILPNIKKNINLLKSII
CCCCCCCHHHHHHHHHHEEEEEEEECCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA