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The map label for this gene is glnS [H]

Identifier: 116515189

GI number: 116515189

Start: 292106

End: 293755

Strand: Direct

Name: glnS [H]

Synonym: BCc_263

Alternate gene names: 116515189

Gene position: 292106-293755 (Clockwise)

Preceding gene: 116515186

Following gene: 116515190

Centisome position: 70.15

GC content: 19.94

Gene sequence:

>1650_bases
ATGAAAAAAAAAAGAAACAGTAATTTTATTATTAATATAGTAAAAAAATCATTAATACAAAATTCAAAAAAAAAAATAAA
AACACGTTTTCCTCCAGAACCTAATGGTTATTTACATATAGGACATGCAAAATCAATTTGTTTAAATTTTAATATTGCAA
AAAAATATAATGGAATTTGCAATCTTAGATTTGATGACACTAATCCAAATAAAGAAAAAATAAAATATATTAATGCTATT
AAAAAAGATATCCGATGGTTAGGATATAAATGGAACGGTAAGACTAAATATACTTCTAATTATTTTGATAAAATGTATAA
ATATGCTATAAAGTTAATTGAAAAAAAATTAGCATATGTAGAAGAACTAAACAAAACTGATATTAAAAAATATAGAGGAA
CATTAAAAAAACCAGGAATAAATAGTCCATATAGAAATCGAACAGTACAAGAAAATTTAATTTTATTTAATAAAATGAAA
CTTGGCATGTTTCCAGAAGGATCTCTTTGTTTAAGAGCTAAAATAGATATGAGTTCTCCATATATTATATTGAGAGATCC
CGTATTATACAGAATTATTTTTTCTAAACATCATCAAACAAATTATAAATGGTATATTTATCCAATGTATGATTTTGCAC
ATTGTATTGCAGATACAATAGAAAAAATTACACATTCCCTATGTACTTTAGAATTTCAAGATAATCGTCAATTATACAAA
TGGATATTAAAAAAACTAAATTTTAAGAATAAAACACCTAAACAATATGAATATTCAAAATTAAATTTAGAATACACTAT
TGTATCTAAACGAAAGATACAAAAATTAATTGATAATAAAATAGTAAAAGGATGGAAAGATTCAAGATTATATACTATAT
CTGGACTAAGAAATAGAGGATATACAAAAAAATCAATTAATACTTTTTGTCAAAAAATTGGAATAACTAAACAACAAAAT
ACAATAGAAATATCATTATTAGAATCATGTATAAGAAAAGAACTTAATATGAATTCTCCAAGAAGAATGGCAATTCTTAA
TCCAATTAAAGTAATAATTACTAATATTTCAAGAAAAGATATTAAATATTTAAATATCCCAAATCATCCACAAAAAAAAG
AAATGGGAACTAGAAAAGTACTTTTTTCTAATAAAATATATATTGAAAAAAAAGATTTTTCTGAAAAAAATATAACAGGA
TATAGAGGATTAATTTTAGGAAAAAGAGTACGATTAAAATATTCTTATATTATTAAAGCAAACAAAATCTTAAAAGACAA
AAATAATCAAATAATTTGTATTTTATGTACATATTATTCAAAAAAAAAATATAATAATATATATAAAGATAAAAATATTG
GTATAATTCACTGGATAGCAAAAAATAATTCAATTGTAGCTGATTTTCAATTATTTGATACATTATTTACTACTAAAAAT
CCTGAAAAAGAAAAAAATATTTTAAAATTTTATAATCCAAAATCGTTTATTATTAAAAGAGGATATGTAGAATCAATTAT
TCAAAAAGAAAAAATAAAACATGCATATCAATTTGAAAGAATTGGATATTTTTATAAAAGAAAAAAAAGAAAAAATATAG
AAGTATTTAATAGAATTGTATCATTAAAAAAAAGATATAAAAATAATTAA

Upstream 100 bases:

>100_bases
TTATAATATAAATATAATTACTTATATTTATATTTATATTTAATTATTATTAAAATTTAATAAAATAAATAATTTAATAA
ATAATTAATAAAGGCAATGT

Downstream 100 bases:

>100_bases
GACAATTTATTTTAAAAAAAAAATTTTATTAAATAAAATTAAATTTTCATTAAAAAATTAATATATTTTAAAGGCTATAA
TATGTCAAAAATAAAAAAAA

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS [H]

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MKKKRNSNFIINIVKKSLIQNSKKKIKTRFPPEPNGYLHIGHAKSICLNFNIAKKYNGICNLRFDDTNPNKEKIKYINAI
KKDIRWLGYKWNGKTKYTSNYFDKMYKYAIKLIEKKLAYVEELNKTDIKKYRGTLKKPGINSPYRNRTVQENLILFNKMK
LGMFPEGSLCLRAKIDMSSPYIILRDPVLYRIIFSKHHQTNYKWYIYPMYDFAHCIADTIEKITHSLCTLEFQDNRQLYK
WILKKLNFKNKTPKQYEYSKLNLEYTIVSKRKIQKLIDNKIVKGWKDSRLYTISGLRNRGYTKKSINTFCQKIGITKQQN
TIEISLLESCIRKELNMNSPRRMAILNPIKVIITNISRKDIKYLNIPNHPQKKEMGTRKVLFSNKIYIEKKDFSEKNITG
YRGLILGKRVRLKYSYIIKANKILKDKNNQIICILCTYYSKKKYNNIYKDKNIGIIHWIAKNNSIVADFQLFDTLFTTKN
PEKEKNILKFYNPKSFIIKRGYVESIIQKEKIKHAYQFERIGYFYKRKKRKNIEVFNRIVSLKKRYKNN

Sequences:

>Translated_549_residues
MKKKRNSNFIINIVKKSLIQNSKKKIKTRFPPEPNGYLHIGHAKSICLNFNIAKKYNGICNLRFDDTNPNKEKIKYINAI
KKDIRWLGYKWNGKTKYTSNYFDKMYKYAIKLIEKKLAYVEELNKTDIKKYRGTLKKPGINSPYRNRTVQENLILFNKMK
LGMFPEGSLCLRAKIDMSSPYIILRDPVLYRIIFSKHHQTNYKWYIYPMYDFAHCIADTIEKITHSLCTLEFQDNRQLYK
WILKKLNFKNKTPKQYEYSKLNLEYTIVSKRKIQKLIDNKIVKGWKDSRLYTISGLRNRGYTKKSINTFCQKIGITKQQN
TIEISLLESCIRKELNMNSPRRMAILNPIKVIITNISRKDIKYLNIPNHPQKKEMGTRKVLFSNKIYIEKKDFSEKNITG
YRGLILGKRVRLKYSYIIKANKILKDKNNQIICILCTYYSKKKYNNIYKDKNIGIIHWIAKNNSIVADFQLFDTLFTTKN
PEKEKNILKFYNPKSFIIKRGYVESIIQKEKIKHAYQFERIGYFYKRKKRKNIEVFNRIVSLKKRYKNN
>Mature_549_residues
MKKKRNSNFIINIVKKSLIQNSKKKIKTRFPPEPNGYLHIGHAKSICLNFNIAKKYNGICNLRFDDTNPNKEKIKYINAI
KKDIRWLGYKWNGKTKYTSNYFDKMYKYAIKLIEKKLAYVEELNKTDIKKYRGTLKKPGINSPYRNRTVQENLILFNKMK
LGMFPEGSLCLRAKIDMSSPYIILRDPVLYRIIFSKHHQTNYKWYIYPMYDFAHCIADTIEKITHSLCTLEFQDNRQLYK
WILKKLNFKNKTPKQYEYSKLNLEYTIVSKRKIQKLIDNKIVKGWKDSRLYTISGLRNRGYTKKSINTFCQKIGITKQQN
TIEISLLESCIRKELNMNSPRRMAILNPIKVIITNISRKDIKYLNIPNHPQKKEMGTRKVLFSNKIYIEKKDFSEKNITG
YRGLILGKRVRLKYSYIIKANKILKDKNNQIICILCTYYSKKKYNNIYKDKNIGIIHWIAKNNSIVADFQLFDTLFTTKN
PEKEKNILKFYNPKSFIIKRGYVESIIQKEKIKHAYQFERIGYFYKRKKRKNIEVFNRIVSLKKRYKNN

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI4826960, Length=541, Percent_Identity=39.3715341959335, Blast_Score=412, Evalue=1e-115,
Organism=Homo sapiens, GI62241042, Length=380, Percent_Identity=37.1052631578947, Blast_Score=245, Evalue=9e-65,
Organism=Escherichia coli, GI1786895, Length=547, Percent_Identity=52.1023765996344, Blast_Score=635, Evalue=0.0,
Organism=Escherichia coli, GI1788743, Length=95, Percent_Identity=33.6842105263158, Blast_Score=70, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17543332, Length=538, Percent_Identity=39.0334572490706, Blast_Score=379, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI17511007, Length=378, Percent_Identity=33.0687830687831, Blast_Score=206, Evalue=2e-53,
Organism=Saccharomyces cerevisiae, GI6324742, Length=573, Percent_Identity=37.17277486911, Blast_Score=358, Evalue=1e-99,
Organism=Saccharomyces cerevisiae, GI6321192, Length=526, Percent_Identity=31.7490494296578, Blast_Score=268, Evalue=2e-72,
Organism=Drosophila melanogaster, GI17864488, Length=536, Percent_Identity=39.1791044776119, Blast_Score=404, Evalue=1e-113,
Organism=Drosophila melanogaster, GI24649466, Length=368, Percent_Identity=36.6847826086957, Blast_Score=233, Evalue=2e-61,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C [H]

EC number: =6.1.1.18 [H]

Molecular weight: Translated: 65666; Mature: 65666

Theoretical pI: Translated: 10.68; Mature: 10.68

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKRNSNFIINIVKKSLIQNSKKKIKTRFPPEPNGYLHIGHAKSICLNFNIAKKYNGIC
CCCCCCCCCEEHHHHHHHHHCHHHHHCCCCCCCCCCEEEECCCCEEEEEEEEHHHCCCEE
NLRFDDTNPNKEKIKYINAIKKDIRWLGYKWNGKTKYTSNYFDKMYKYAIKLIEKKLAYV
EEEECCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
EELNKTDIKKYRGTLKKPGINSPYRNRTVQENLILFNKMKLGMFPEGSLCLRAKIDMSSP
HHCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHEEEEEEEEECCCCCCCEEEEEEECCCCC
YIILRDPVLYRIIFSKHHQTNYKWYIYPMYDFAHCIADTIEKITHSLCTLEFQDNRQLYK
EEEEECCHHEEHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHH
WILKKLNFKNKTPKQYEYSKLNLEYTIVSKRKIQKLIDNKIVKGWKDSRLYTISGLRNRG
HHHHHCCCCCCCCCCCEEEEEEEEEEEECHHHHHHHHHHHHHCCCCCCEEEEEECCCCCC
YTKKSINTFCQKIGITKQQNTIEISLLESCIRKELNMNSPRRMAILNPIKVIITNISRKD
CCHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHCCCCCCCEEEHHCHHHHHHCCCCCCC
IKYLNIPNHPQKKEMGTRKVLFSNKIYIEKKDFSEKNITGYRGLILGKRVRLKYSYIIKA
EEEECCCCCCCHHHCCCEEEEEECEEEEEECCCCCCCCCCCHHEEECCEEEEEEEEEEEE
NKILKDKNNQIICILCTYYSKKKYNNIYKDKNIGIIHWIAKNNSIVADFQLFDTLFTTKN
HHHHCCCCCCEEEEEEECCCHHHHCCCCCCCCCEEEEEEECCCCEEEHHHHHHHHHCCCC
PEKEKNILKFYNPKSFIIKRGYVESIIQKEKIKHAYQFERIGYFYKRKKRKNIEVFNRIV
CCHHHCHHEEECCCHHEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
SLKKRYKNN
HHHHHHCCC
>Mature Secondary Structure
MKKKRNSNFIINIVKKSLIQNSKKKIKTRFPPEPNGYLHIGHAKSICLNFNIAKKYNGIC
CCCCCCCCCEEHHHHHHHHHCHHHHHCCCCCCCCCCEEEECCCCEEEEEEEEHHHCCCEE
NLRFDDTNPNKEKIKYINAIKKDIRWLGYKWNGKTKYTSNYFDKMYKYAIKLIEKKLAYV
EEEECCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
EELNKTDIKKYRGTLKKPGINSPYRNRTVQENLILFNKMKLGMFPEGSLCLRAKIDMSSP
HHCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHEEEEEEEEECCCCCCCEEEEEEECCCCC
YIILRDPVLYRIIFSKHHQTNYKWYIYPMYDFAHCIADTIEKITHSLCTLEFQDNRQLYK
EEEEECCHHEEHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHH
WILKKLNFKNKTPKQYEYSKLNLEYTIVSKRKIQKLIDNKIVKGWKDSRLYTISGLRNRG
HHHHHCCCCCCCCCCCEEEEEEEEEEEECHHHHHHHHHHHHHCCCCCCEEEEEECCCCCC
YTKKSINTFCQKIGITKQQNTIEISLLESCIRKELNMNSPRRMAILNPIKVIITNISRKD
CCHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHCCCCCCCEEEHHCHHHHHHCCCCCCC
IKYLNIPNHPQKKEMGTRKVLFSNKIYIEKKDFSEKNITGYRGLILGKRVRLKYSYIIKA
EEEECCCCCCCHHHCCCEEEEEECEEEEEECCCCCCCCCCCHHEEECCEEEEEEEEEEEE
NKILKDKNNQIICILCTYYSKKKYNNIYKDKNIGIIHWIAKNNSIVADFQLFDTLFTTKN
HHHHCCCCCCEEEEEEECCCHHHHCCCCCCCCCEEEEEEECCCCEEEHHHHHHHHHCCCC
PEKEKNILKFYNPKSFIIKRGYVESIIQKEKIKHAYQFERIGYFYKRKKRKNIEVFNRIV
CCHHHCHHEEECCCHHEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
SLKKRYKNN
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA