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The map label for this gene is aroQ

Identifier: 116515182

GI number: 116515182

Start: 284943

End: 285401

Strand: Direct

Name: aroQ

Synonym: BCc_251

Alternate gene names: 116515182

Gene position: 284943-285401 (Clockwise)

Preceding gene: 116515181

Following gene: 116515184

Centisome position: 68.43

GC content: 22.88

Gene sequence:

>459_bases
ATGAAAAAAAAAATTAATATATTGTTAATTAACGGACCTAATTTAAATTTATTAGGAACAAGAGAACCAGAAATATATGG
AAAAAAAACACTAGAACAAATAGTTAATAAAATTAAAAAAAAATCAATTCTTTTAAATGTTACTTTATATGATTTTCAAT
CTAATGCAGAACATAAAATAGTAGAAAAAATACATAATTGTAAGAAAAATAATATACAATTTATTTTAATTAATCCCGGT
GCTTTTACTCATACTAGTATTTCTATACGAGATGCTTTATCAGCTATAAATATACCATTTTTTGAAATTCATATATCTAA
CATCTTTGCTAGAGAAAATTTTAGATCTCACTCCTGGATGTCTGATATAGCACAAGGTGTTATATCAGGTTTTGGAAATT
ACGGATATCAAATAGCATTAAAGACTGCAGTAAAATTTTTATTAGAAAAAGAAAAATAA

Upstream 100 bases:

>100_bases
TTATATTTTTTATAAAAAACTATAATTTTTTTTTTAAAATGTTATTATATAATAATATAATTATTTTAATTTATAAATTT
TTATTTATATGGTAGATATT

Downstream 100 bases:

>100_bases
TTAATTTTTATTTTTTATAAAAAACAATATATATAATATTTATATATTAAAATTTTTTGATTTTTTAAAGATATTATTTT
TATAATAAATATTTAATTTT

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MKKKINILLINGPNLNLLGTREPEIYGKKTLEQIVNKIKKKSILLNVTLYDFQSNAEHKIVEKIHNCKKNNIQFILINPG
AFTHTSISIRDALSAINIPFFEIHISNIFARENFRSHSWMSDIAQGVISGFGNYGYQIALKTAVKFLLEKEK

Sequences:

>Translated_152_residues
MKKKINILLINGPNLNLLGTREPEIYGKKTLEQIVNKIKKKSILLNVTLYDFQSNAEHKIVEKIHNCKKNNIQFILINPG
AFTHTSISIRDALSAINIPFFEIHISNIFARENFRSHSWMSDIAQGVISGFGNYGYQIALKTAVKFLLEKEK
>Mature_152_residues
MKKKINILLINGPNLNLLGTREPEIYGKKTLEQIVNKIKKKSILLNVTLYDFQSNAEHKIVEKIHNCKKNNIQFILINPG
AFTHTSISIRDALSAINIPFFEIHISNIFARENFRSHSWMSDIAQGVISGFGNYGYQIALKTAVKFLLEKEK

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ_BUCCC (Q057I1)

Other databases:

- EMBL:   CP000263
- RefSeq:   YP_802811.1
- ProteinModelPortal:   Q057I1
- SMR:   Q057I1
- STRING:   Q057I1
- EnsemblBacteria:   EBBUCT00000001224
- GeneID:   4440755
- GenomeReviews:   CP000263_GR
- KEGG:   bcc:BCc_251
- eggNOG:   COG0757
- GeneTree:   EBGT00050000008123
- HOGENOM:   HBG284657
- OMA:   HSYIAPI
- BioCyc:   BAPH372461:BCC_251-MONOMER
- HAMAP:   MF_00169
- InterPro:   IPR001874
- InterPro:   IPR018509
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 17357; Mature: 17357

Theoretical pI: Translated: 10.35; Mature: 10.35

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 26-26 ACT_SITE 104-104 BINDING 78-78 BINDING 84-84 BINDING 91-91 BINDING 115-115

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKINILLINGPNLNLLGTREPEIYGKKTLEQIVNKIKKKSILLNVTLYDFQSNAEHKI
CCCEEEEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHCEEEEEEEEEECCCCCHHHH
VEKIHNCKKNNIQFILINPGAFTHTSISIRDALSAINIPFFEIHISNIFARENFRSHSWM
HHHHHCCCCCCEEEEEECCCCCEECEEHHHHHHHHHCCCEEEEEEEHHHHHCCCCCCHHH
SDIAQGVISGFGNYGYQIALKTAVKFLLEKEK
HHHHHHHHHCCCCCCEEEHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKKINILLINGPNLNLLGTREPEIYGKKTLEQIVNKIKKKSILLNVTLYDFQSNAEHKI
CCCEEEEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHCEEEEEEEEEECCCCCHHHH
VEKIHNCKKNNIQFILINPGAFTHTSISIRDALSAINIPFFEIHISNIFARENFRSHSWM
HHHHHCCCCCCEEEEEECCCCCEECEEHHHHHHHHHCCCEEEEEEEHHHHHCCCCCCHHH
SDIAQGVISGFGNYGYQIALKTAVKFLLEKEK
HHHHHHHHHCCCCCCEEEHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA