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The map label for this gene is hisS [H]

Identifier: 116515113

GI number: 116515113

Start: 205733

End: 207010

Strand: Direct

Name: hisS [H]

Synonym: BCc_177

Alternate gene names: 116515113

Gene position: 205733-207010 (Clockwise)

Preceding gene: 116515112

Following gene: 116515114

Centisome position: 49.41

GC content: 19.25

Gene sequence:

>1278_bases
ATGAATGTGTCATATCGATCAATTCGCGGAATGCACGATCTTTTTTTTTTAGATACTTACGAATTAAATCGAATAGAAGT
AATAATTAAAAATATAGTACATTCCTATGCATTTTCAGAAATTAGATTACCAATAGTTGAAGAAACAAGATTATTTACTA
AAGCTATTGGAAATGATACTGATATTATTAATAAAGAAATGTATAATTTTTATGATAAAAAAAAAAAAAAAATTTCTTTA
CGACCAGAAGGAACAGTAGGTTGTATTCGTGCATGTATACAAAATAACATTTTTTATCAATCTCAAATTCAAAAATTTTG
GTATCACGGTCCCATGTTTCGTTATGAACGACCTCAAAAAGGACGTTTTAGACAATTTCATCAATTTGGAATAGAATTAT
TCGGCTCAAAAAATATAATTTCTGATTATGAACTTATTATATTAACAATAAATATTTGGAAAAAATTAAATATATTAAAA
TATTTAACTTTAGAAATAAATTCAATTGGTTCTATAGAAGATAGAGTAAAATACTCTTTGGATTTAAATAGTTTTTTAAA
AAAAAATATACATAAAATAAAAAAAAATAAAAAAAAAATATTATTAAATAATTCTATTAGATTATTAGATAATAAGGATA
TTTATATAAAAAAACTATTAAAATCTGCTCCAATATTAAAAAATTATTTAAATTTACAATCATGTATTCGTTTTAAAAAA
CTATGTAATTTATTACATTATTTTAAAATAAAATTTATTATAAATAAAAAACTAGTTAGAGGATTAGATTATTATAATGA
TACAGTATTTGAATGGAAATCTAATCTTTTAGGATCAAAAAATACTATTTGTGCAGGCGGTCGTTATGATCATTTAGTAA
AATTTTTAGGAGGAAAAGACAATCCAGCAATTGGTGTAGCTATAGGAATGGATAGATTATTACTTTTAATAAAATCTATT
TATTTAAATAAATATAATTTTTTTCTTATAGATGTTAATATTATTTTTTTAGAATCAATATATTTAAAATTAGCTATAAA
AATATCAGAAGAATTGCGTGTTCTTTGGCCTGTTTTAAAAATTAATACATGTTTAAATATTATTAAAAAAAAAAATTTTT
TTAAATATTCTAAAACATCAAAATCAAAATATTTATTAATTTTATCATCTACATTTTTAAAAAATAATAAAATTCATTTA
ATAAATATTTCAAAAAAAGAAAAAAAAACAATAAATTTTACTAGAATTTTTCAAAATCCGTGTATTTTTAATCATTAA

Upstream 100 bases:

>100_bases
TGGGCAATTAATAGCTTAATATTATTTTAAATAAGTAATATTTATTTATAAATATTAAGTACACAAATAATAATAGTATT
AATATAGGAAATTATAAAAT

Downstream 100 bases:

>100_bases
TTATGATATATAGTTATTTTTATATTTTTAAAAATTTTAATATTATTAAATAAATATATATTAAATAATATAAATTTATT
ATCATTTTTAAAATAAATAT

Product: hypothetical protein

Products: NA

Alternate protein names: Histidine--tRNA ligase; HisRS [H]

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MNVSYRSIRGMHDLFFLDTYELNRIEVIIKNIVHSYAFSEIRLPIVEETRLFTKAIGNDTDIINKEMYNFYDKKKKKISL
RPEGTVGCIRACIQNNIFYQSQIQKFWYHGPMFRYERPQKGRFRQFHQFGIELFGSKNIISDYELIILTINIWKKLNILK
YLTLEINSIGSIEDRVKYSLDLNSFLKKNIHKIKKNKKKILLNNSIRLLDNKDIYIKKLLKSAPILKNYLNLQSCIRFKK
LCNLLHYFKIKFIINKKLVRGLDYYNDTVFEWKSNLLGSKNTICAGGRYDHLVKFLGGKDNPAIGVAIGMDRLLLLIKSI
YLNKYNFFLIDVNIIFLESIYLKLAIKISEELRVLWPVLKINTCLNIIKKKNFFKYSKTSKSKYLLILSSTFLKNNKIHL
INISKKEKKTINFTRIFQNPCIFNH

Sequences:

>Translated_425_residues
MNVSYRSIRGMHDLFFLDTYELNRIEVIIKNIVHSYAFSEIRLPIVEETRLFTKAIGNDTDIINKEMYNFYDKKKKKISL
RPEGTVGCIRACIQNNIFYQSQIQKFWYHGPMFRYERPQKGRFRQFHQFGIELFGSKNIISDYELIILTINIWKKLNILK
YLTLEINSIGSIEDRVKYSLDLNSFLKKNIHKIKKNKKKILLNNSIRLLDNKDIYIKKLLKSAPILKNYLNLQSCIRFKK
LCNLLHYFKIKFIINKKLVRGLDYYNDTVFEWKSNLLGSKNTICAGGRYDHLVKFLGGKDNPAIGVAIGMDRLLLLIKSI
YLNKYNFFLIDVNIIFLESIYLKLAIKISEELRVLWPVLKINTCLNIIKKKNFFKYSKTSKSKYLLILSSTFLKNNKIHL
INISKKEKKTINFTRIFQNPCIFNH
>Mature_425_residues
MNVSYRSIRGMHDLFFLDTYELNRIEVIIKNIVHSYAFSEIRLPIVEETRLFTKAIGNDTDIINKEMYNFYDKKKKKISL
RPEGTVGCIRACIQNNIFYQSQIQKFWYHGPMFRYERPQKGRFRQFHQFGIELFGSKNIISDYELIILTINIWKKLNILK
YLTLEINSIGSIEDRVKYSLDLNSFLKKNIHKIKKNKKKILLNNSIRLLDNKDIYIKKLLKSAPILKNYLNLQSCIRFKK
LCNLLHYFKIKFIINKKLVRGLDYYNDTVFEWKSNLLGSKNTICAGGRYDHLVKFLGGKDNPAIGVAIGMDRLLLLIKSI
YLNKYNFFLIDVNIIFLESIYLKLAIKISEELRVLWPVLKINTCLNIIKKKNFFKYSKTSKSKYLLILSSTFLKNNKIHL
INISKKEKKTINFTRIFQNPCIFNH

Specific function: Unknown

COG id: COG0124

COG function: function code J; Histidyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1788861, Length=406, Percent_Identity=42.1182266009852, Blast_Score=362, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR015807
- InterPro:   IPR004516 [H]

Pfam domain/function: PF00587 tRNA-synt_2b [H]

EC number: =6.1.1.21 [H]

Molecular weight: Translated: 50341; Mature: 50341

Theoretical pI: Translated: 10.49; Mature: 10.49

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVSYRSIRGMHDLFFLDTYELNRIEVIIKNIVHSYAFSEIRLPIVEETRLFTKAIGNDT
CCCCHHHHCCCHHEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCH
DIINKEMYNFYDKKKKKISLRPEGTVGCIRACIQNNIFYQSQIQKFWYHGPMFRYERPQK
HHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCEECCCCCC
GRFRQFHQFGIELFGSKNIISDYELIILTINIWKKLNILKYLTLEINSIGSIEDRVKYSL
CHHHHHHHHHHHEECCCCCCCCCEEEEEEEEHHHHHCCCEEEEEEECCCCCHHHHHEEEE
DLNSFLKKNIHKIKKNKKKILLNNSIRLLDNKDIYIKKLLKSAPILKNYLNLQSCIRFKK
CHHHHHHHHHHHHHCCCCEEEEECCEEEEECCCHHHHHHHHHCHHHHHHHHHHHHHHHHH
LCNLLHYFKIKFIINKKLVRGLDYYNDTVFEWKSNLLGSKNTICAGGRYDHLVKFLGGKD
HHHHHHHHHHHHEECHHHHHHHHHCCCHHHHHHHHCCCCCCCEECCCCHHHHHHHHCCCC
NPAIGVAIGMDRLLLLIKSIYLNKYNFFLIDVNIIFLESIYLKLAIKISEELRVLWPVLK
CCEEEEEECHHHHHHHHHHHHHCCEEEEEEEEHHHHHHHHHHHHEEEHHHHHHHHHHHHH
INTCLNIIKKKNFFKYSKTSKSKYLLILSSTFLKNNKIHLINISKKEKKTINFTRIFQNP
HHHHHHHHHHCCCEEECCCCCCEEEEEEEEHHHCCCCEEEEECCCCCCHHEEHEEEECCC
CIFNH
CCCCC
>Mature Secondary Structure
MNVSYRSIRGMHDLFFLDTYELNRIEVIIKNIVHSYAFSEIRLPIVEETRLFTKAIGNDT
CCCCHHHHCCCHHEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCH
DIINKEMYNFYDKKKKKISLRPEGTVGCIRACIQNNIFYQSQIQKFWYHGPMFRYERPQK
HHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCEECCCCCC
GRFRQFHQFGIELFGSKNIISDYELIILTINIWKKLNILKYLTLEINSIGSIEDRVKYSL
CHHHHHHHHHHHEECCCCCCCCCEEEEEEEEHHHHHCCCEEEEEEECCCCCHHHHHEEEE
DLNSFLKKNIHKIKKNKKKILLNNSIRLLDNKDIYIKKLLKSAPILKNYLNLQSCIRFKK
CHHHHHHHHHHHHHCCCCEEEEECCEEEEECCCHHHHHHHHHCHHHHHHHHHHHHHHHHH
LCNLLHYFKIKFIINKKLVRGLDYYNDTVFEWKSNLLGSKNTICAGGRYDHLVKFLGGKD
HHHHHHHHHHHHEECHHHHHHHHHCCCHHHHHHHHCCCCCCCEECCCCHHHHHHHHCCCC
NPAIGVAIGMDRLLLLIKSIYLNKYNFFLIDVNIIFLESIYLKLAIKISEELRVLWPVLK
CCEEEEEECHHHHHHHHHHHHHCCEEEEEEEEHHHHHHHHHHHHEEEHHHHHHHHHHHHH
INTCLNIIKKKNFFKYSKTSKSKYLLILSSTFLKNNKIHLINISKKEKKTINFTRIFQNP
HHHHHHHHHHCCCEEECCCCCCEEEEEEEEHHHCCCCEEEEECCCCCCHHEEHEEEECCC
CIFNH
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10993077 [H]