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The map label for this gene is sppA [H]

Identifier: 116515107

GI number: 116515107

Start: 199051

End: 200916

Strand: Reverse

Name: sppA [H]

Synonym: BCc_171

Alternate gene names: 116515107

Gene position: 200916-199051 (Counterclockwise)

Preceding gene: 116515108

Following gene: 116515101

Centisome position: 48.25

GC content: 18.7

Gene sequence:

>1866_bases
ATGAAAATTTTTTTTTTAATAATATTAAAAATATTTAAATTTATATCAATAACATATAATTTAATAAAAAAAATATTTTT
AAATATTTTTATATTATTATTTTTAAGTATTTTTGTTCTTTTAATATATGAAATTAAAAAAAAAAATATATTTTTTTCAA
AAAACAATAAATCAGGAATTCTAGTTATTGATTTAAATCAGACTCTCAAAGAAGAACCAATTAGAAATATATCTTTATAT
AAACATCATAATTATTTTTTAAATTTTTTTAATTGGAGTAATAATTCTTCTGTTTATGAAATTACTAAAAAAATTGAACA
GGCTAAAGAAGACCCTAAAATAAAAGGAATACAATTAAATTTTTCAGATTCATTTACTAGTAATCAAGTTATATTAGAAT
ATTTTGGAAAAAAATTATATGAATTTAAACAATCCAACAAACCAATTATATCAATAGGTAAAAATTATTCACAAAGCGGA
TATTATTTAGCTAGTTTTTCAAATAAAATTTTTTTATTACCCGATGGTTCTGTACATATTAATGGTATTGCAAATACCAA
AATATTTTTGAAAAAAATTATAGATACATTAAAAATTCATTTACATGTTTTTAGAATCGGAAAATATAAAAATGCTGTAG
AATCTGTTTTAAGAAATTCTCCTTCTAAAATAAATAAGAAAATTGATCAATTAATCATTCGTTTTAAATGGAAAAAATAT
TTACAAAAAATTGCTAGTAATAGAAATACTGTTCTAACAGAAATATGTCCTAATCCTAATATTTTTACAAAATTTTTTAA
AAAAAAAAATAATAATTATACAAAATATGCCTTATATCACAATTTAGTAGATAAAATTCTTAAAAAAAATAGTATTAAAA
AATATTTAAATAATTTTTTTAAAAATAAAGATAAAAATTATAATTATAATTTTATTAATATAAATAATTATTATATTAAT
AAAAAGAAAATAACTTTAAATTCGAATAAAATCAAAGTTATAATTTCTAATGGAATTATTGAAAATAATTGTAAGAGATC
CGCTAATTTAAATATTGAAAATTTATTAAATGAAATTGATGAAGCAAAAAATGATTCTAGCGTTAAAGCTGTAATATTAC
GTATAAATAGTCCAGGTGGAACTGTTAAATATTCAGAAATTATAAGAAAAAAATTATTAGAATTACATAAATGTAATAAA
CCATTGATTATTTCTATGGGTGATGTATGTGCCTCTGGAGGATATTGGATATCAACAGCAGGAGATTATATAATTGCTCA
TGATACTACATTAACTGGATCTATTGGAATATTTGCTGTAATACCTACAATTGAAAAAATATTATCAACTATAGGAATTA
AACAATATCAAATAAAAACAAAATATTATGAAGATTTCAGTATTTTTCATGAATTATCTGAACAAAGTAAAAAAAGTATT
GGTGATAATATTATTAGAGAATATAAAAAATTTATTACAATAGTAGCACAATCTCGAAAATTATCATATAAAAAAACACA
TAGTATTTCACAAGGAAGAGTCTGGACAGGTTATCAAGCTCAAAAAATAGGATTAGTAGATGAAATAGGAGATTTGGATC
ATGCAATTAAAAAAGCTGCTCAATTAGCAAATATTAAAAATTATTGTGTTATCTGGTCTAAATTAGAAAAAAAATCAACA
GCAAATGTTACAAGTAACATGAATAATTCAATAAATATTAAACAAAAAAATATTTTGAACATGCTTATTAAAAGATTTTT
TATAAATAAAAATTTATTTGAACAAGATAATTTATATCTTTTTTATAAAATAATTTTTTCTAAAAAAATATTTTCTCTTT
GTTTAGAGAATTTTGTTTTTAAATAA

Upstream 100 bases:

>100_bases
ATAATTTTAATATTAAAATATAATAAAATATTTATAAAATTTTTTATAAAAAAAATTAATAAATATTATAAAAAGCAAAT
TAAAAAGGGTTAATATCAAT

Downstream 100 bases:

>100_bases
AAATAATTAAAATACATAAAACACCAACAAAAAATTAATAATATTTTTTGGTGTTCTTATATATTTTTTGTTTATATCAA
TATGTTTTTTTTAATAAAAA

Product: hypothetical protein

Products: NA

Alternate protein names: Endopeptidase IV; Protease IV; Signal peptide peptidase [H]

Number of amino acids: Translated: 621; Mature: 621

Protein sequence:

>621_residues
MKIFFLIILKIFKFISITYNLIKKIFLNIFILLFLSIFVLLIYEIKKKNIFFSKNNKSGILVIDLNQTLKEEPIRNISLY
KHHNYFLNFFNWSNNSSVYEITKKIEQAKEDPKIKGIQLNFSDSFTSNQVILEYFGKKLYEFKQSNKPIISIGKNYSQSG
YYLASFSNKIFLLPDGSVHINGIANTKIFLKKIIDTLKIHLHVFRIGKYKNAVESVLRNSPSKINKKIDQLIIRFKWKKY
LQKIASNRNTVLTEICPNPNIFTKFFKKKNNNYTKYALYHNLVDKILKKNSIKKYLNNFFKNKDKNYNYNFININNYYIN
KKKITLNSNKIKVIISNGIIENNCKRSANLNIENLLNEIDEAKNDSSVKAVILRINSPGGTVKYSEIIRKKLLELHKCNK
PLIISMGDVCASGGYWISTAGDYIIAHDTTLTGSIGIFAVIPTIEKILSTIGIKQYQIKTKYYEDFSIFHELSEQSKKSI
GDNIIREYKKFITIVAQSRKLSYKKTHSISQGRVWTGYQAQKIGLVDEIGDLDHAIKKAAQLANIKNYCVIWSKLEKKST
ANVTSNMNNSINIKQKNILNMLIKRFFINKNLFEQDNLYLFYKIIFSKKIFSLCLENFVFK

Sequences:

>Translated_621_residues
MKIFFLIILKIFKFISITYNLIKKIFLNIFILLFLSIFVLLIYEIKKKNIFFSKNNKSGILVIDLNQTLKEEPIRNISLY
KHHNYFLNFFNWSNNSSVYEITKKIEQAKEDPKIKGIQLNFSDSFTSNQVILEYFGKKLYEFKQSNKPIISIGKNYSQSG
YYLASFSNKIFLLPDGSVHINGIANTKIFLKKIIDTLKIHLHVFRIGKYKNAVESVLRNSPSKINKKIDQLIIRFKWKKY
LQKIASNRNTVLTEICPNPNIFTKFFKKKNNNYTKYALYHNLVDKILKKNSIKKYLNNFFKNKDKNYNYNFININNYYIN
KKKITLNSNKIKVIISNGIIENNCKRSANLNIENLLNEIDEAKNDSSVKAVILRINSPGGTVKYSEIIRKKLLELHKCNK
PLIISMGDVCASGGYWISTAGDYIIAHDTTLTGSIGIFAVIPTIEKILSTIGIKQYQIKTKYYEDFSIFHELSEQSKKSI
GDNIIREYKKFITIVAQSRKLSYKKTHSISQGRVWTGYQAQKIGLVDEIGDLDHAIKKAAQLANIKNYCVIWSKLEKKST
ANVTSNMNNSINIKQKNILNMLIKRFFINKNLFEQDNLYLFYKIIFSKKIFSLCLENFVFK
>Mature_621_residues
MKIFFLIILKIFKFISITYNLIKKIFLNIFILLFLSIFVLLIYEIKKKNIFFSKNNKSGILVIDLNQTLKEEPIRNISLY
KHHNYFLNFFNWSNNSSVYEITKKIEQAKEDPKIKGIQLNFSDSFTSNQVILEYFGKKLYEFKQSNKPIISIGKNYSQSG
YYLASFSNKIFLLPDGSVHINGIANTKIFLKKIIDTLKIHLHVFRIGKYKNAVESVLRNSPSKINKKIDQLIIRFKWKKY
LQKIASNRNTVLTEICPNPNIFTKFFKKKNNNYTKYALYHNLVDKILKKNSIKKYLNNFFKNKDKNYNYNFININNYYIN
KKKITLNSNKIKVIISNGIIENNCKRSANLNIENLLNEIDEAKNDSSVKAVILRINSPGGTVKYSEIIRKKLLELHKCNK
PLIISMGDVCASGGYWISTAGDYIIAHDTTLTGSIGIFAVIPTIEKILSTIGIKQYQIKTKYYEDFSIFHELSEQSKKSI
GDNIIREYKKFITIVAQSRKLSYKKTHSISQGRVWTGYQAQKIGLVDEIGDLDHAIKKAAQLANIKNYCVIWSKLEKKST
ANVTSNMNNSINIKQKNILNMLIKRFFINKNLFEQDNLYLFYKIIFSKKIFSLCLENFVFK

Specific function: Digestion of the cleaved signal peptides. This activity is necessary to maintain proper secretion of mature proteins across the membrane [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1788064, Length=586, Percent_Identity=34.1296928327645, Blast_Score=363, Evalue=1e-101,
Organism=Escherichia coli, GI1787527, Length=167, Percent_Identity=28.7425149700599, Blast_Score=78, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004634
- InterPro:   IPR004635
- InterPro:   IPR002142 [H]

Pfam domain/function: PF01343 Peptidase_S49 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 72331; Mature: 72331

Theoretical pI: Translated: 10.44; Mature: 10.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIFFLIILKIFKFISITYNLIKKIFLNIFILLFLSIFVLLIYEIKKKNIFFSKNNKSGI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCEE
LVIDLNQTLKEEPIRNISLYKHHNYFLNFFNWSNNSSVYEITKKIEQAKEDPKIKGIQLN
EEEECCHHHHHCCCCCCEEEEECCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEE
FSDSFTSNQVILEYFGKKLYEFKQSNKPIISIGKNYSQSGYYLASFSNKIFLLPDGSVHI
CCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEECCCEEEEEECCCEEE
NGIANTKIFLKKIIDTLKIHLHVFRIGKYKNAVESVLRNSPSKINKKIDQLIIRFKWKKY
EECCCHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LQKIASNRNTVLTEICPNPNIFTKFFKKKNNNYTKYALYHNLVDKILKKNSIKKYLNNFF
HHHHHCCCCEEEEEECCCCCHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
KNKDKNYNYNFININNYYINKKKITLNSNKIKVIISNGIIENNCKRSANLNIENLLNEID
CCCCCCCCEEEEEEEEEEEEEEEEEEECCEEEEEEECCEECCCCCCCCCCCHHHHHHHHH
EAKNDSSVKAVILRINSPGGTVKYSEIIRKKLLELHKCNKPLIISMGDVCASGGYWISTA
HCCCCCCEEEEEEEEECCCCCEEHHHHHHHHHHHHHHCCCCEEEEECHHHCCCCEEEECC
GDYIIAHDTTLTGSIGIFAVIPTIEKILSTIGIKQYQIKTKYYEDFSIFHELSEQSKKSI
CCEEEEECCEEECCCHHEEHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHH
GDNIIREYKKFITIVAQSRKLSYKKTHSISQGRVWTGYQAQKIGLVDEIGDLDHAIKKAA
HHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEECCCCHHHCCCHHHHHHHHHHHHHHH
QLANIKNYCVIWSKLEKKSTANVTSNMNNSINIKQKNILNMLIKRFFINKNLFEQDNLYL
HHHCCCCCEEEEHHHHCCCCCCHHCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCEEE
FYKIIFSKKIFSLCLENFVFK
EHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIFFLIILKIFKFISITYNLIKKIFLNIFILLFLSIFVLLIYEIKKKNIFFSKNNKSGI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCEE
LVIDLNQTLKEEPIRNISLYKHHNYFLNFFNWSNNSSVYEITKKIEQAKEDPKIKGIQLN
EEEECCHHHHHCCCCCCEEEEECCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEE
FSDSFTSNQVILEYFGKKLYEFKQSNKPIISIGKNYSQSGYYLASFSNKIFLLPDGSVHI
CCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEECCCEEEEEECCCEEE
NGIANTKIFLKKIIDTLKIHLHVFRIGKYKNAVESVLRNSPSKINKKIDQLIIRFKWKKY
EECCCHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LQKIASNRNTVLTEICPNPNIFTKFFKKKNNNYTKYALYHNLVDKILKKNSIKKYLNNFF
HHHHHCCCCEEEEEECCCCCHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
KNKDKNYNYNFININNYYINKKKITLNSNKIKVIISNGIIENNCKRSANLNIENLLNEID
CCCCCCCCEEEEEEEEEEEEEEEEEEECCEEEEEEECCEECCCCCCCCCCCHHHHHHHHH
EAKNDSSVKAVILRINSPGGTVKYSEIIRKKLLELHKCNKPLIISMGDVCASGGYWISTA
HCCCCCCEEEEEEEEECCCCCEEHHHHHHHHHHHHHHCCCCEEEEECHHHCCCCEEEECC
GDYIIAHDTTLTGSIGIFAVIPTIEKILSTIGIKQYQIKTKYYEDFSIFHELSEQSKKSI
CCEEEEECCEEECCCHHEEHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHH
GDNIIREYKKFITIVAQSRKLSYKKTHSISQGRVWTGYQAQKIGLVDEIGDLDHAIKKAA
HHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEECCCCHHHCCCHHHHHHHHHHHHHHH
QLANIKNYCVIWSKLEKKSTANVTSNMNNSINIKQKNILNMLIKRFFINKNLFEQDNLYL
HHHCCCCCEEEEHHHHCCCCCCHHCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCEEE
FYKIIFSKKIFSLCLENFVFK
EHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]