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The map label for this gene is rnb [H]

Identifier: 116515104

GI number: 116515104

Start: 195292

End: 197238

Strand: Direct

Name: rnb [H]

Synonym: BCc_168

Alternate gene names: 116515104

Gene position: 195292-197238 (Clockwise)

Preceding gene: 116515103

Following gene: 116515105

Centisome position: 46.9

GC content: 20.18

Gene sequence:

>1947_bases
ATGTTTTATAATAATCCTTTACTTATAAAATTAAAAAATAAATTATATAAAAAAAAAAAAATAGAAGGAATAGTTAAAAG
TACTACAAAAGGATTTGGATTTTTAGAAGTCGATTCTAAAAAAACATATTTTATTCCTTCAAAAAATATGAAGAAAGTTA
TTCATGGAGACCGTATTATAGGTCTAATTAAATTAGAAAATAACAAAGAAATAGTATATCCAAAAATATTAATTGAACCC
TTTTTAAAAAAATTTATTGGATCAATATTAAAAAAAAATAATATTATATATATACAAGCAAATTATCCGTATATTAAAGA
TTTAATTTTTTATCGATATAAAACATCAGTTTTCAGATCTTGGAAAAATGGAGATTGGGTAATAGCAGAATTAGATACAC
ATAGTTTACGAGATAATAATCATTTTAGTATTAATATACTAAAATTTATTTCTGAAAAAAATGATCCATTAACTCCATGG
AATGTAATTTTATCAAAATATAATTTAGAAAAAAAATCTCCAAAAATTAATTTTAATTATATATTAAATAATAATAATTT
AAAAGATAAACGAATAGATTTAACATATTTAGATTTTATTACTATTGATAATAGTAATACGCAAGATATTGATGATGCTC
TTTTTGTAAAGAAAACAAAAAAAAATAAATTAACATTAATTGTTGCTATCGCAGATCCAACTGAATATATATTAATTAAT
ACTAAAGTTGACGATATAGCAAAAAAAAGAGTTTTTACAAATTATTTACCTGGCTTTAATATATCTATGTTACCTAAAGA
ATTTTCTGAAGATCTTTGTTCATTAAAACCACATGTAAAGCGACCTGTATTAGCATGTAAGATAATCATTGATAATGAAG
GAAAAATTTTAATGAAAAAAACAAAATTTTTTTTAGCATGGATTGAATCAAAAGGTAAATTATCGTATCAAAATGTATCA
AATTGGTTAGAAAAATTAGGAAATTGGCAACCAGATAACAAAAAAATTAAAAAACAAATTTTATTACTATATAAAATGTA
TAAAATTAGAAATATGTGGAGAAAAAAAAATGCATTAATATTTCCAGATAATATTGAATATAAATTTCATTTATCAAAAA
CATGGGAAATTTTAAATATTTCAGTAGAAAAAAGAAGTATTGCACATAAAATTGTTGAAGAGTCTATGATTTCAGCTAAT
ATTTGTGCTGCTAGTTTCTTAAAAAAAAAATTAGGTTTTGGATTATATAATTCACATTCTGGTTTTGATACTTTTAACGC
AAAAAATGCTATTAATTTTTTAAAAAAATATAATATTATTTTTACTTTAGAAGAAATTATGACATTATCTGGATTTTGTA
AATTAAAACGAAAATTAAATAAATTATCTAATAAATATATTAATTATAGAATTCAAAAATTTCAGTCTTTTGGAGAAATA
AGTTTAATACCTAAACCACATTTTTCTCTTGGACTTCCATATTATGCTACTTGGACATCTCCAATTAGAAAATATAGTGA
TATGATTAATCATAGATTAATTAAATCTATAATTATAGGAAAAAAAAAAATTTCTCCTCCTGATACAAATATTATTCCTC
AAATAATACATCGTAAATATAAAATTCGTATGGCTTTAAAAGAAATAGAGGAATGGTTATATTTTAAATACTATAATAAA
AAAAAAAGTGACAAAAAAAAATATCAAGCTAATATTATTGATATTTCTAAAGGAGGAATTAAAGCTCGTTTATTGAAAAC
TGGTGCTTATATTTTTATTCCAGTTACTTATATTCATAAAATTCGTCATGAATTAAATCTTAATTCTGAAAAAGGAATAA
TATATATAAAAAATAAGATTTATTATAAAGTATCTGATATTATTATAGTATCTTTGTTAAAGATAAATAATGGTAATAAA
AAAATTATAGCAACTATGATAAATTAA

Upstream 100 bases:

>100_bases
AAAATATATTTTTATATATAAATATTTTATATATCATTTTTTTCTAAAAGTAAAAAATTATTTTTCTTTAAAAATCATAC
TAAAATTAGGTTATCATATT

Downstream 100 bases:

>100_bases
CATTTTATTAAAAATTTTTTATCTAATTAAATATTAAATTTAATAAATAATTATTTTTATTAATTTATTCAATAAATATA
TAAATTTTTAAAATGAATAT

Product: exoribonuclease II

Products: NA

Alternate protein names: Exoribonuclease II; RNase II; Ribonuclease II [H]

Number of amino acids: Translated: 648; Mature: 648

Protein sequence:

>648_residues
MFYNNPLLIKLKNKLYKKKKIEGIVKSTTKGFGFLEVDSKKTYFIPSKNMKKVIHGDRIIGLIKLENNKEIVYPKILIEP
FLKKFIGSILKKNNIIYIQANYPYIKDLIFYRYKTSVFRSWKNGDWVIAELDTHSLRDNNHFSINILKFISEKNDPLTPW
NVILSKYNLEKKSPKINFNYILNNNNLKDKRIDLTYLDFITIDNSNTQDIDDALFVKKTKKNKLTLIVAIADPTEYILIN
TKVDDIAKKRVFTNYLPGFNISMLPKEFSEDLCSLKPHVKRPVLACKIIIDNEGKILMKKTKFFLAWIESKGKLSYQNVS
NWLEKLGNWQPDNKKIKKQILLLYKMYKIRNMWRKKNALIFPDNIEYKFHLSKTWEILNISVEKRSIAHKIVEESMISAN
ICAASFLKKKLGFGLYNSHSGFDTFNAKNAINFLKKYNIIFTLEEIMTLSGFCKLKRKLNKLSNKYINYRIQKFQSFGEI
SLIPKPHFSLGLPYYATWTSPIRKYSDMINHRLIKSIIIGKKKISPPDTNIIPQIIHRKYKIRMALKEIEEWLYFKYYNK
KKSDKKKYQANIIDISKGGIKARLLKTGAYIFIPVTYIHKIRHELNLNSEKGIIYIKNKIYYKVSDIIIVSLLKINNGNK
KIIATMIN

Sequences:

>Translated_648_residues
MFYNNPLLIKLKNKLYKKKKIEGIVKSTTKGFGFLEVDSKKTYFIPSKNMKKVIHGDRIIGLIKLENNKEIVYPKILIEP
FLKKFIGSILKKNNIIYIQANYPYIKDLIFYRYKTSVFRSWKNGDWVIAELDTHSLRDNNHFSINILKFISEKNDPLTPW
NVILSKYNLEKKSPKINFNYILNNNNLKDKRIDLTYLDFITIDNSNTQDIDDALFVKKTKKNKLTLIVAIADPTEYILIN
TKVDDIAKKRVFTNYLPGFNISMLPKEFSEDLCSLKPHVKRPVLACKIIIDNEGKILMKKTKFFLAWIESKGKLSYQNVS
NWLEKLGNWQPDNKKIKKQILLLYKMYKIRNMWRKKNALIFPDNIEYKFHLSKTWEILNISVEKRSIAHKIVEESMISAN
ICAASFLKKKLGFGLYNSHSGFDTFNAKNAINFLKKYNIIFTLEEIMTLSGFCKLKRKLNKLSNKYINYRIQKFQSFGEI
SLIPKPHFSLGLPYYATWTSPIRKYSDMINHRLIKSIIIGKKKISPPDTNIIPQIIHRKYKIRMALKEIEEWLYFKYYNK
KKSDKKKYQANIIDISKGGIKARLLKTGAYIFIPVTYIHKIRHELNLNSEKGIIYIKNKIYYKVSDIIIVSLLKINNGNK
KIIATMIN
>Mature_648_residues
MFYNNPLLIKLKNKLYKKKKIEGIVKSTTKGFGFLEVDSKKTYFIPSKNMKKVIHGDRIIGLIKLENNKEIVYPKILIEP
FLKKFIGSILKKNNIIYIQANYPYIKDLIFYRYKTSVFRSWKNGDWVIAELDTHSLRDNNHFSINILKFISEKNDPLTPW
NVILSKYNLEKKSPKINFNYILNNNNLKDKRIDLTYLDFITIDNSNTQDIDDALFVKKTKKNKLTLIVAIADPTEYILIN
TKVDDIAKKRVFTNYLPGFNISMLPKEFSEDLCSLKPHVKRPVLACKIIIDNEGKILMKKTKFFLAWIESKGKLSYQNVS
NWLEKLGNWQPDNKKIKKQILLLYKMYKIRNMWRKKNALIFPDNIEYKFHLSKTWEILNISVEKRSIAHKIVEESMISAN
ICAASFLKKKLGFGLYNSHSGFDTFNAKNAINFLKKYNIIFTLEEIMTLSGFCKLKRKLNKLSNKYINYRIQKFQSFGEI
SLIPKPHFSLGLPYYATWTSPIRKYSDMINHRLIKSIIIGKKKISPPDTNIIPQIIHRKYKIRMALKEIEEWLYFKYYNK
KKSDKKKYQANIIDISKGGIKARLLKTGAYIFIPVTYIHKIRHELNLNSEKGIIYIKNKIYYKVSDIIIVSLLKINNGNK
KIIATMIN

Specific function: Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction [H]

COG id: COG4776

COG function: function code K; Exoribonuclease II

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014623, Length=351, Percent_Identity=27.9202279202279, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI190014625, Length=353, Percent_Identity=27.1954674220963, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI134288890, Length=428, Percent_Identity=25.2336448598131, Blast_Score=96, Evalue=1e-19,
Organism=Escherichia coli, GI1787542, Length=645, Percent_Identity=46.3565891472868, Blast_Score=636, Evalue=0.0,
Organism=Escherichia coli, GI87082383, Length=517, Percent_Identity=25.7253384912959, Blast_Score=160, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI212645896, Length=362, Percent_Identity=27.3480662983425, Blast_Score=109, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17553506, Length=491, Percent_Identity=24.4399185336049, Blast_Score=93, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6324552, Length=362, Percent_Identity=26.5193370165746, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323943, Length=356, Percent_Identity=26.9662921348315, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24649634, Length=394, Percent_Identity=28.4263959390863, Blast_Score=118, Evalue=2e-26,
Organism=Drosophila melanogaster, GI19922976, Length=400, Percent_Identity=26.25, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24654597, Length=400, Percent_Identity=26.25, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24654592, Length=400, Percent_Identity=26.25, Blast_Score=103, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011804 [H]

Pfam domain/function: PF08206 OB_RNB; PF00773 RNB [H]

EC number: =3.1.13.1 [H]

Molecular weight: Translated: 76185; Mature: 76185

Theoretical pI: Translated: 10.53; Mature: 10.53

Prosite motif: PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFYNNPLLIKLKNKLYKKKKIEGIVKSTTKGFGFLEVDSKKTYFIPSKNMKKVIHGDRII
CCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEECCCCHHHHHCCCEEE
GLIKLENNKEIVYPKILIEPFLKKFIGSILKKNNIIYIQANYPYIKDLIFYRYKTSVFRS
EEEEECCCCEEEEHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHC
WKNGDWVIAELDTHSLRDNNHFSINILKFISEKNDPLTPWNVILSKYNLEKKSPKINFNY
CCCCCEEEEECCCCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHCCCCCCCCEEEEEE
ILNNNNLKDKRIDLTYLDFITIDNSNTQDIDDALFVKKTKKNKLTLIVAIADPTEYILIN
EEECCCCCCCEEEEEEEEEEEECCCCCCCCCHHHEEEECCCCEEEEEEEEECCCEEEEEE
TKVDDIAKKRVFTNYLPGFNISMLPKEFSEDLCSLKPHVKRPVLACKIIIDNEGKILMKK
CCHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHCCCCCCCCCEEEEEEEECCCCCEEEEE
TKFFLAWIESKGKLSYQNVSNWLEKLGNWQPDNKKIKKQILLLYKMYKIRNMWRKKNALI
HEEEEEEECCCCCEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEE
FPDNIEYKFHLSKTWEILNISVEKRSIAHKIVEESMISANICAASFLKKKLGFGLYNSHS
CCCCCEEEEEECCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCC
GFDTFNAKNAINFLKKYNIIFTLEEIMTLSGFCKLKRKLNKLSNKYINYRIQKFQSFGEI
CCCCCCHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
SLIPKPHFSLGLPYYATWTSPIRKYSDMINHRLIKSIIIGKKKISPPDTNIIPQIIHRKY
EECCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
KIRMALKEIEEWLYFKYYNKKKSDKKKYQANIIDISKGGIKARLLKTGAYIFIPVTYIHK
HHHHHHHHHHHHHEEEEECCCCCCCHHHEEEEEEECCCCCEEEEEECCCEEEEEHHHHHH
IRHELNLNSEKGIIYIKNKIYYKVSDIIIVSLLKINNGNKKIIATMIN
HHHHCCCCCCCCEEEEECEEEEEEHHEEEEEEEEECCCCCEEEEEEEC
>Mature Secondary Structure
MFYNNPLLIKLKNKLYKKKKIEGIVKSTTKGFGFLEVDSKKTYFIPSKNMKKVIHGDRII
CCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEECCCCHHHHHCCCEEE
GLIKLENNKEIVYPKILIEPFLKKFIGSILKKNNIIYIQANYPYIKDLIFYRYKTSVFRS
EEEEECCCCEEEEHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHC
WKNGDWVIAELDTHSLRDNNHFSINILKFISEKNDPLTPWNVILSKYNLEKKSPKINFNY
CCCCCEEEEECCCCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHCCCCCCCCEEEEEE
ILNNNNLKDKRIDLTYLDFITIDNSNTQDIDDALFVKKTKKNKLTLIVAIADPTEYILIN
EEECCCCCCCEEEEEEEEEEEECCCCCCCCCHHHEEEECCCCEEEEEEEEECCCEEEEEE
TKVDDIAKKRVFTNYLPGFNISMLPKEFSEDLCSLKPHVKRPVLACKIIIDNEGKILMKK
CCHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHCCCCCCCCCEEEEEEEECCCCCEEEEE
TKFFLAWIESKGKLSYQNVSNWLEKLGNWQPDNKKIKKQILLLYKMYKIRNMWRKKNALI
HEEEEEEECCCCCEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEE
FPDNIEYKFHLSKTWEILNISVEKRSIAHKIVEESMISANICAASFLKKKLGFGLYNSHS
CCCCCEEEEEECCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCC
GFDTFNAKNAINFLKKYNIIFTLEEIMTLSGFCKLKRKLNKLSNKYINYRIQKFQSFGEI
CCCCCCHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
SLIPKPHFSLGLPYYATWTSPIRKYSDMINHRLIKSIIIGKKKISPPDTNIIPQIIHRKY
EECCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
KIRMALKEIEEWLYFKYYNKKKSDKKKYQANIIDISKGGIKARLLKTGAYIFIPVTYIHK
HHHHHHHHHHHHHEEEEECCCCCCCHHHEEEEEEECCCCCEEEEEECCCEEEEEHHHHHH
IRHELNLNSEKGIIYIKNKIYYKVSDIIIVSLLKINNGNKKIIATMIN
HHHHCCCCCCCCEEEEECEEEEEEHHEEEEEEEEECCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA