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The map label for this gene is aceE [H]

Identifier: 116515071

GI number: 116515071

Start: 152550

End: 155210

Strand: Direct

Name: aceE [H]

Synonym: BCc_131

Alternate gene names: 116515071

Gene position: 152550-155210 (Clockwise)

Preceding gene: 116515070

Following gene: 116515072

Centisome position: 36.64

GC content: 25.44

Gene sequence:

>2661_bases
ATGTCAAAAGATATTTTTAAAGATACTGATATTCTTGAAACTAATGAATGGATAGAATCAATTAATTCTGTAATTTCTAG
ATGTGGTAAGAAAAGAGCTTGTTTTTTAATAAATAAATTATTAAATTTAGATGTATTACAAGATTATCATTTATATAAAA
AAAATTTTACTCATTATATTAATACTATTCATGTTAATGATGAATTTAAATATCCTGGTAATATTTATTTAGAAGAAAAA
ATTTGTTCAGCTGTTCGTTGGAATGCTATTATGATAGTATTACATGCTTCGAGAAAAAATTTAGATTTAGGTGGACATAT
TTCTTCTTTTCAATCTTCCGCTATGATTTATGAAGTGTGTTTTAATCATTTTTTTCGCGCTTCTAATAATTATGATGGAG
GTGATTTAATTTATTTTCAAGGGCATTCAGCTCCAGGTATTTATGCTAGAGCATTTTTAGAAAATCGTTTAACAGATAAA
CAAATGTATAATTTTAGACAAGAAACTAATAATTTAGGTTTATCTTCGTATCCTCATCCTAAATTAATGTCTAATTTTTG
GCAATTTCCAACTGTTTCTATGGGTTTAAGTGCAATTTCTGCAATCTATCAAGCAAAATTTTTAAAATATTTAATGAATA
GAAATTTGAAAGATACATCTAAACAAAAAGTTTATGCTTTTTTAGGTGATGGAGAAATGGATGAATCAGAATCAAAAGGA
GCTATAACAATAGCAGCAAGGGAAAAATTAGATAATTTAATCTTTGTAGTGAATTGTAATTTACAACGTTTAGATGGTCC
GGTGTTAGGAAACGGGAAAATTATTAATGAATTAAATGATATTTTTTCTGGTGCAGGTTGGTATGTTATTAAGGTAATTT
GGGGAAGTGAATGGGATTATTTATTAAAAAAAGATTATTCAGGACATTTAAAAAAATTAATGAATGAAACATTAGATGGA
GATTATCAAACTTTTAGTTCAAAAAATGGTGCTTATATTCGTAAACATTTTTTTGGTAGATATAAAGAAACTAAAAAATT
AGTAGAAAATATGACAGACAATGATATTGAAAATTTAAAAAAGGGTGGGCATGATTTTAAAAAAATTTATTCAGCTTTTT
GTTTAGCACAATCAATAAAAAATAAACCAGTTATTATATTAATACATACTATTAAGGGATATGGTTTAGGGAAAATTGCT
GAAGGAAAAAATATTGCTCATCAAATAAAGAATTTAGATATACAAGATTTAGAACATTTAAAAAAACATTTAAAAATAGA
ATTAGATTCTAAATCCACAAAACAATTATCTTTTATAAAATTTTCTTCTAATTCTGAAGAATATAAATATATATGTAATC
AAAGAAAAAAATTATATGGATATGTTCCTAAAAGATTAGAAAATTTTACTGAAAAATTAGTTATACCAGAATTAAATGAT
TTTTCTTCTTTATTTAAAGAACAAAAAAGACCAATTTCAACAACTGTTATTTTTATTCGAATATTAAATATTTTATTAAA
AAATATTCATTTAAAAAATAGAATTGTTCCAATTATTGCAGATGAAGCTCGTACTTTCGGTATGGAAGGTTTTTTTCGTC
AGATTGGAATTTATAATTATCAAGGACAAAAATATATACCAGCTGATAAAGATCAGTTTTTTTATTATAAAGAAGATTAT
ACGGGACAAATTTTACAAGAAGGTATAAATGAATTAGGTGCTTGTTCTTCTTGGTTAGCTGCAGCTACTTCTTATAGTAC
TAATAATTTTCCAATGATACCTTTTTATATTTATTATTCCATGTTTGGTTTTCAAAGAATAGGAGATTTTTTATGGTCTT
GTGGAGATCAAAAAGCTAGGGGTTTTTTAATAGGTGCTACTGCAGGTAAAACTACTTTAAATGGAGAAGGATTACAACAT
GCTGATGGTCATAGTCATATTTTATCATCTACTATTCCTAATTGTGTATCGTATGATCCAACATATAGTTATGAACTTGC
AGTAATTATACAATCTGGATTAACTAGAATGTATGGAGAAAAACAAGAAGATATTTTTTATTATATTACTACATATAATG
AAAATTATGTAATGCCTAAAATGTCTGAAGATATGGTTTATGGTATTTGTAAAGGAGCATATAAATTAGATACTTTAAAA
GGAAATAATGGTCATATTCAATTTTTAGGGTCAGGTTCTATTTTATGTGTTATAAGAAATGCAGCTGATATCTTATTGTC
AGATTATAATATTGGTTCTGATATTTATAGTGTTACTTCATTTACAGAAATTGCTCGTGATGGTCAAGATTGTTTTCGTT
GGAATATGCGAAATCCTTTGAGTAAAAAAAGAACACCGTATATTACTAGTATTATGAATAATTCTCCTGCTATTGCAGTT
ACAGATTATATGAAAATTTTTTCAGAACAAATTCGTGCATATATACCTGCAAAAGTATTTAATGTTTTAGGAACAGATGG
ATATGGTAGATCAGATAGTCGTGAAAAATTACGTTGTTTTTTTGAAATTGACGAAACAAATATTATTTGTTCTGCATTAC
ATGCATTAGTAGTACAAGGTGATATAGATTCTAGTATATTTTTAGATGCATTAAAAAAATTTAATATTTTTTCAAATAAA
TTGAATCCACGTTTAGCATAA

Upstream 100 bases:

>100_bases
AAATCATTTTTAATATTTAATATTTTTAAAGAAATAAGTAATAAACTATTTAAAATTAATTTATAAAATTTTAAGTTTAA
TATTTAAAGGATTATGAAAT

Downstream 100 bases:

>100_bases
GAGGTGATATAGTGGACGTAGAAGTTCGTGTACCAGATATTGGAATTAAAGATGTTGAAGTAATTGAAATTTTCGTAAAA
AAAGGAGATATAGTTAGTAA

Product: pyruvate dehydrogenase subunit E1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 886; Mature: 885

Protein sequence:

>886_residues
MSKDIFKDTDILETNEWIESINSVISRCGKKRACFLINKLLNLDVLQDYHLYKKNFTHYINTIHVNDEFKYPGNIYLEEK
ICSAVRWNAIMIVLHASRKNLDLGGHISSFQSSAMIYEVCFNHFFRASNNYDGGDLIYFQGHSAPGIYARAFLENRLTDK
QMYNFRQETNNLGLSSYPHPKLMSNFWQFPTVSMGLSAISAIYQAKFLKYLMNRNLKDTSKQKVYAFLGDGEMDESESKG
AITIAAREKLDNLIFVVNCNLQRLDGPVLGNGKIINELNDIFSGAGWYVIKVIWGSEWDYLLKKDYSGHLKKLMNETLDG
DYQTFSSKNGAYIRKHFFGRYKETKKLVENMTDNDIENLKKGGHDFKKIYSAFCLAQSIKNKPVIILIHTIKGYGLGKIA
EGKNIAHQIKNLDIQDLEHLKKHLKIELDSKSTKQLSFIKFSSNSEEYKYICNQRKKLYGYVPKRLENFTEKLVIPELND
FSSLFKEQKRPISTTVIFIRILNILLKNIHLKNRIVPIIADEARTFGMEGFFRQIGIYNYQGQKYIPADKDQFFYYKEDY
TGQILQEGINELGACSSWLAAATSYSTNNFPMIPFYIYYSMFGFQRIGDFLWSCGDQKARGFLIGATAGKTTLNGEGLQH
ADGHSHILSSTIPNCVSYDPTYSYELAVIIQSGLTRMYGEKQEDIFYYITTYNENYVMPKMSEDMVYGICKGAYKLDTLK
GNNGHIQFLGSGSILCVIRNAADILLSDYNIGSDIYSVTSFTEIARDGQDCFRWNMRNPLSKKRTPYITSIMNNSPAIAV
TDYMKIFSEQIRAYIPAKVFNVLGTDGYGRSDSREKLRCFFEIDETNIICSALHALVVQGDIDSSIFLDALKKFNIFSNK
LNPRLA

Sequences:

>Translated_886_residues
MSKDIFKDTDILETNEWIESINSVISRCGKKRACFLINKLLNLDVLQDYHLYKKNFTHYINTIHVNDEFKYPGNIYLEEK
ICSAVRWNAIMIVLHASRKNLDLGGHISSFQSSAMIYEVCFNHFFRASNNYDGGDLIYFQGHSAPGIYARAFLENRLTDK
QMYNFRQETNNLGLSSYPHPKLMSNFWQFPTVSMGLSAISAIYQAKFLKYLMNRNLKDTSKQKVYAFLGDGEMDESESKG
AITIAAREKLDNLIFVVNCNLQRLDGPVLGNGKIINELNDIFSGAGWYVIKVIWGSEWDYLLKKDYSGHLKKLMNETLDG
DYQTFSSKNGAYIRKHFFGRYKETKKLVENMTDNDIENLKKGGHDFKKIYSAFCLAQSIKNKPVIILIHTIKGYGLGKIA
EGKNIAHQIKNLDIQDLEHLKKHLKIELDSKSTKQLSFIKFSSNSEEYKYICNQRKKLYGYVPKRLENFTEKLVIPELND
FSSLFKEQKRPISTTVIFIRILNILLKNIHLKNRIVPIIADEARTFGMEGFFRQIGIYNYQGQKYIPADKDQFFYYKEDY
TGQILQEGINELGACSSWLAAATSYSTNNFPMIPFYIYYSMFGFQRIGDFLWSCGDQKARGFLIGATAGKTTLNGEGLQH
ADGHSHILSSTIPNCVSYDPTYSYELAVIIQSGLTRMYGEKQEDIFYYITTYNENYVMPKMSEDMVYGICKGAYKLDTLK
GNNGHIQFLGSGSILCVIRNAADILLSDYNIGSDIYSVTSFTEIARDGQDCFRWNMRNPLSKKRTPYITSIMNNSPAIAV
TDYMKIFSEQIRAYIPAKVFNVLGTDGYGRSDSREKLRCFFEIDETNIICSALHALVVQGDIDSSIFLDALKKFNIFSNK
LNPRLA
>Mature_885_residues
SKDIFKDTDILETNEWIESINSVISRCGKKRACFLINKLLNLDVLQDYHLYKKNFTHYINTIHVNDEFKYPGNIYLEEKI
CSAVRWNAIMIVLHASRKNLDLGGHISSFQSSAMIYEVCFNHFFRASNNYDGGDLIYFQGHSAPGIYARAFLENRLTDKQ
MYNFRQETNNLGLSSYPHPKLMSNFWQFPTVSMGLSAISAIYQAKFLKYLMNRNLKDTSKQKVYAFLGDGEMDESESKGA
ITIAAREKLDNLIFVVNCNLQRLDGPVLGNGKIINELNDIFSGAGWYVIKVIWGSEWDYLLKKDYSGHLKKLMNETLDGD
YQTFSSKNGAYIRKHFFGRYKETKKLVENMTDNDIENLKKGGHDFKKIYSAFCLAQSIKNKPVIILIHTIKGYGLGKIAE
GKNIAHQIKNLDIQDLEHLKKHLKIELDSKSTKQLSFIKFSSNSEEYKYICNQRKKLYGYVPKRLENFTEKLVIPELNDF
SSLFKEQKRPISTTVIFIRILNILLKNIHLKNRIVPIIADEARTFGMEGFFRQIGIYNYQGQKYIPADKDQFFYYKEDYT
GQILQEGINELGACSSWLAAATSYSTNNFPMIPFYIYYSMFGFQRIGDFLWSCGDQKARGFLIGATAGKTTLNGEGLQHA
DGHSHILSSTIPNCVSYDPTYSYELAVIIQSGLTRMYGEKQEDIFYYITTYNENYVMPKMSEDMVYGICKGAYKLDTLKG
NNGHIQFLGSGSILCVIRNAADILLSDYNIGSDIYSVTSFTEIARDGQDCFRWNMRNPLSKKRTPYITSIMNNSPAIAVT
DYMKIFSEQIRAYIPAKVFNVLGTDGYGRSDSREKLRCFFEIDETNIICSALHALVVQGDIDSSIFLDALKKFNIFSNKL
NPRLA

Specific function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydroge

COG id: COG2609

COG function: function code C; Pyruvate dehydrogenase complex, dehydrogenase (E1) component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786304, Length=887, Percent_Identity=64.0360766629087, Blast_Score=1223, Evalue=0.0,

Paralogues:

None

Copy number: 1140 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 400 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004660
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =1.2.4.1 [H]

Molecular weight: Translated: 101533; Mature: 101402

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKDIFKDTDILETNEWIESINSVISRCGKKRACFLINKLLNLDVLQDYHLYKKNFTHYI
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
NTIHVNDEFKYPGNIYLEEKICSAVRWNAIMIVLHASRKNLDLGGHISSFQSSAMIYEVC
EEEEECCCCCCCCCEEEHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
FNHFFRASNNYDGGDLIYFQGHSAPGIYARAFLENRLTDKQMYNFRQETNNLGLSSYPHP
HHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCH
KLMSNFWQFPTVSMGLSAISAIYQAKFLKYLMNRNLKDTSKQKVYAFLGDGEMDESESKG
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCC
AITIAAREKLDNLIFVVNCNLQRLDGPVLGNGKIINELNDIFSGAGWYVIKVIWGSEWDY
EEEEEEHHCCCCEEEEEECCHHCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEECCCCCH
LLKKDYSGHLKKLMNETLDGDYQTFSSKNGAYIRKHFFGRYKETKKLVENMTDNDIENLK
HHHCCCHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
KGGHDFKKIYSAFCLAQSIKNKPVIILIHTIKGYGLGKIAEGKNIAHQIKNLDIQDLEHL
HCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHCCCHHHHHHH
KKHLKIELDSKSTKQLSFIKFSSNSEEYKYICNQRKKLYGYVPKRLENFTEKLVIPELND
HHHCEEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCHH
FSSLFKEQKRPISTTVIFIRILNILLKNIHLKNRIVPIIADEARTFGMEGFFRQIGIYNY
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHCCHHHHHHHHCCEEC
QGQKYIPADKDQFFYYKEDYTGQILQEGINELGACSSWLAAATSYSTNNFPMIPFYIYYS
CCCEECCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
MFGFQRIGDFLWSCGDQKARGFLIGATAGKTTLNGEGLQHADGHSHILSSTIPNCVSYDP
HHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCC
TYSYELAVIIQSGLTRMYGEKQEDIFYYITTYNENYVMPKMSEDMVYGICKGAYKLDTLK
CCCEEEEHHHHHHHHHHCCCCCCCEEEEEEEECCCEECCCCCCHHHHHHHCCCEEEEEEE
GNNGHIQFLGSGSILCVIRNAADILLSDYNIGSDIYSVTSFTEIARDGQDCFRWNMRNPL
CCCCEEEEEECCCEEEEEECCCHHEEECCCCCCHHHHHHHHHHHHHCCHHHHHCCCCCCC
SKKRTPYITSIMNNSPAIAVTDYMKIFSEQIRAYIPAKVFNVLGTDGYGRSDSREKLRCF
CCCCCCCEEHHHCCCCCEEHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCEEEEE
FEIDETNIICSALHALVVQGDIDSSIFLDALKKFNIFSNKLNPRLA
EEECCCHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SKDIFKDTDILETNEWIESINSVISRCGKKRACFLINKLLNLDVLQDYHLYKKNFTHYI
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
NTIHVNDEFKYPGNIYLEEKICSAVRWNAIMIVLHASRKNLDLGGHISSFQSSAMIYEVC
EEEEECCCCCCCCCEEEHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
FNHFFRASNNYDGGDLIYFQGHSAPGIYARAFLENRLTDKQMYNFRQETNNLGLSSYPHP
HHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCH
KLMSNFWQFPTVSMGLSAISAIYQAKFLKYLMNRNLKDTSKQKVYAFLGDGEMDESESKG
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCC
AITIAAREKLDNLIFVVNCNLQRLDGPVLGNGKIINELNDIFSGAGWYVIKVIWGSEWDY
EEEEEEHHCCCCEEEEEECCHHCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEECCCCCH
LLKKDYSGHLKKLMNETLDGDYQTFSSKNGAYIRKHFFGRYKETKKLVENMTDNDIENLK
HHHCCCHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
KGGHDFKKIYSAFCLAQSIKNKPVIILIHTIKGYGLGKIAEGKNIAHQIKNLDIQDLEHL
HCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHCCCHHHHHHH
KKHLKIELDSKSTKQLSFIKFSSNSEEYKYICNQRKKLYGYVPKRLENFTEKLVIPELND
HHHCEEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCHH
FSSLFKEQKRPISTTVIFIRILNILLKNIHLKNRIVPIIADEARTFGMEGFFRQIGIYNY
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHCCHHHHHHHHCCEEC
QGQKYIPADKDQFFYYKEDYTGQILQEGINELGACSSWLAAATSYSTNNFPMIPFYIYYS
CCCEECCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
MFGFQRIGDFLWSCGDQKARGFLIGATAGKTTLNGEGLQHADGHSHILSSTIPNCVSYDP
HHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCC
TYSYELAVIIQSGLTRMYGEKQEDIFYYITTYNENYVMPKMSEDMVYGICKGAYKLDTLK
CCCEEEEHHHHHHHHHHCCCCCCCEEEEEEEECCCEECCCCCCHHHHHHHCCCEEEEEEE
GNNGHIQFLGSGSILCVIRNAADILLSDYNIGSDIYSVTSFTEIARDGQDCFRWNMRNPL
CCCCEEEEEECCCEEEEEECCCHHEEECCCCCCHHHHHHHHHHHHHCCHHHHHCCCCCCC
SKKRTPYITSIMNNSPAIAVTDYMKIFSEQIRAYIPAKVFNVLGTDGYGRSDSREKLRCF
CCCCCCCEEHHHCCCCCEEHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCEEEEE
FEIDETNIICSALHALVVQGDIDSSIFLDALKKFNIFSNKLNPRLA
EEECCCHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]