Click here to switch to the map view.

The map label for this gene is ahpC [C]

Identifier: 116515058

GI number: 116515058

Start: 135380

End: 135982

Strand: Reverse

Name: ahpC [C]

Synonym: BCc_117

Alternate gene names: 116515058

Gene position: 135982-135380 (Counterclockwise)

Preceding gene: 116515060

Following gene: 116515057

Centisome position: 32.66

GC content: 24.38

Gene sequence:

>603_bases
ATGACTTTAGTATCTAAAAAAGCACCAAATTTTATTGCTCCAGCTATTTTAAAAAATGGACAAATAATTCAAAATTTTAA
CTTTAAAAATTTTTCTAAAAATAAAACTACTGTATTATTTTTCTGGCCTATGGATTTTACTTTCGTATGTCCTTCTGAGA
TTATAGCATTTAATAATTCATATCATGAATTTAAAGATAGAAATGCATGTATTATAGGAATATCTATTGATTCAGTATAT
ACACATAACGCATGGAGAAATACAAAAATAAATGAAGGAGGAATAGGTCCGATTAAATTTCCAATGATATCTGACATTAC
TAAATCTATACAAAAATCTTATAATATTGAACATGATATACTAACTATTGCATTAAGAGCATCATTTATTATTGATAAAT
CTAATATAATTAGACATCAATCTGTAAATGATTTACCAATTGGAAGAAATATAAAAGAAATACTTCGAATTATTGATGCA
TTACACTATTATGAAAAATTTGGCGAAGTATGTCCTGCGAATTGGAATATAGGAAAAGAAGCAATACAAGCAACTGATGT
AGGAATAAAAAAATATTTATCAAAAAATTCTAAAAAACTATAA

Upstream 100 bases:

>100_bases
ATGAAAAAAAAAAAAACAAAAAATATGTTATAGTATAATAAATTTTTTTAAAAAATATATAAAATACACAATAAAAATTG
AAAAAAAGGTATTAACAAAA

Downstream 100 bases:

>100_bases
TTTTTAATATACAAGTATTATTTAAATTTTATAAAAAATCTTAAAACCATTTATATATTAAAATGGTTTTAATAAAATAA
AAACTTTAAAAAAATACAAT

Product: hypothetical protein

Products: NA

Alternate protein names: Thioredoxin reductase [H]

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MTLVSKKAPNFIAPAILKNGQIIQNFNFKNFSKNKTTVLFFWPMDFTFVCPSEIIAFNNSYHEFKDRNACIIGISIDSVY
THNAWRNTKINEGGIGPIKFPMISDITKSIQKSYNIEHDILTIALRASFIIDKSNIIRHQSVNDLPIGRNIKEILRIIDA
LHYYEKFGEVCPANWNIGKEAIQATDVGIKKYLSKNSKKL

Sequences:

>Translated_200_residues
MTLVSKKAPNFIAPAILKNGQIIQNFNFKNFSKNKTTVLFFWPMDFTFVCPSEIIAFNNSYHEFKDRNACIIGISIDSVY
THNAWRNTKINEGGIGPIKFPMISDITKSIQKSYNIEHDILTIALRASFIIDKSNIIRHQSVNDLPIGRNIKEILRIIDA
LHYYEKFGEVCPANWNIGKEAIQATDVGIKKYLSKNSKKL
>Mature_199_residues
TLVSKKAPNFIAPAILKNGQIIQNFNFKNFSKNKTTVLFFWPMDFTFVCPSEIIAFNNSYHEFKDRNACIIGISIDSVYT
HNAWRNTKINEGGIGPIKFPMISDITKSIQKSYNIEHDILTIALRASFIIDKSNIIRHQSVNDLPIGRNIKEILRIIDAL
HYYEKFGEVCPANWNIGKEAIQATDVGIKKYLSKNSKKL

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4505591, Length=197, Percent_Identity=43.1472081218274, Blast_Score=176, Evalue=1e-44,
Organism=Homo sapiens, GI32455266, Length=197, Percent_Identity=43.1472081218274, Blast_Score=176, Evalue=1e-44,
Organism=Homo sapiens, GI32455264, Length=197, Percent_Identity=43.1472081218274, Blast_Score=176, Evalue=1e-44,
Organism=Homo sapiens, GI32189392, Length=193, Percent_Identity=40.9326424870466, Blast_Score=175, Evalue=2e-44,
Organism=Homo sapiens, GI5802974, Length=192, Percent_Identity=42.7083333333333, Blast_Score=175, Evalue=3e-44,
Organism=Homo sapiens, GI32483377, Length=191, Percent_Identity=42.9319371727749, Blast_Score=174, Evalue=5e-44,
Organism=Homo sapiens, GI5453549, Length=192, Percent_Identity=42.1875, Blast_Score=171, Evalue=5e-43,
Organism=Homo sapiens, GI33188454, Length=82, Percent_Identity=42.6829268292683, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1786822, Length=183, Percent_Identity=33.3333333333333, Blast_Score=106, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI193204376, Length=195, Percent_Identity=38.974358974359, Blast_Score=160, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI32565831, Length=195, Percent_Identity=38.974358974359, Blast_Score=160, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI17554494, Length=195, Percent_Identity=37.4358974358974, Blast_Score=152, Evalue=8e-38,
Organism=Caenorhabditis elegans, GI25153706, Length=199, Percent_Identity=26.6331658291457, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6323613, Length=195, Percent_Identity=38.4615384615385, Blast_Score=152, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6320661, Length=194, Percent_Identity=38.659793814433, Blast_Score=145, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6319407, Length=187, Percent_Identity=32.0855614973262, Blast_Score=92, Evalue=7e-20,
Organism=Drosophila melanogaster, GI17738015, Length=196, Percent_Identity=43.8775510204082, Blast_Score=176, Evalue=1e-44,
Organism=Drosophila melanogaster, GI17157991, Length=197, Percent_Identity=41.1167512690355, Blast_Score=170, Evalue=5e-43,
Organism=Drosophila melanogaster, GI24641739, Length=197, Percent_Identity=41.1167512690355, Blast_Score=170, Evalue=5e-43,
Organism=Drosophila melanogaster, GI24656348, Length=194, Percent_Identity=42.2680412371134, Blast_Score=169, Evalue=8e-43,
Organism=Drosophila melanogaster, GI17864676, Length=194, Percent_Identity=42.2680412371134, Blast_Score=169, Evalue=8e-43,
Organism=Drosophila melanogaster, GI21357347, Length=193, Percent_Identity=35.2331606217617, Blast_Score=151, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24581278, Length=185, Percent_Identity=27.027027027027, Blast_Score=81, Evalue=4e-16,
Organism=Drosophila melanogaster, GI17975518, Length=206, Percent_Identity=28.6407766990291, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24652434, Length=206, Percent_Identity=28.1553398058252, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24652436, Length=185, Percent_Identity=28.6486486486486, Blast_Score=74, Evalue=7e-14,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 22842; Mature: 22711

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLVSKKAPNFIAPAILKNGQIIQNFNFKNFSKNKTTVLFFWPMDFTFVCPSEIIAFNNS
CCCCCCCCCCCHHHHHHCCCEEEECCCCCCCCCCCCEEEEEECCCEEEECCHHHEEECCC
YHEFKDRNACIIGISIDSVYTHNAWRNTKINEGGIGPIKFPMISDITKSIQKSYNIEHDI
HHHHCCCCEEEEEEEECCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHH
LTIALRASFIIDKSNIIRHQSVNDLPIGRNIKEILRIIDALHYYEKFGEVCPANWNIGKE
HHHEEHHHEEECCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
AIQATDVGIKKYLSKNSKKL
HHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TLVSKKAPNFIAPAILKNGQIIQNFNFKNFSKNKTTVLFFWPMDFTFVCPSEIIAFNNS
CCCCCCCCCCHHHHHHCCCEEEECCCCCCCCCCCCEEEEEECCCEEEECCHHHEEECCC
YHEFKDRNACIIGISIDSVYTHNAWRNTKINEGGIGPIKFPMISDITKSIQKSYNIEHDI
HHHHCCCCEEEEEEEECCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHH
LTIALRASFIIDKSNIIRHQSVNDLPIGRNIKEILRIIDALHYYEKFGEVCPANWNIGKE
HHHEEHHHEEECCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
AIQATDVGIKKYLSKNSKKL
HHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438 [H]