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The map label for this gene is ackA

Identifier: 116515055

GI number: 116515055

Start: 130297

End: 131517

Strand: Direct

Name: ackA

Synonym: BCc_114

Alternate gene names: 116515055

Gene position: 130297-131517 (Clockwise)

Preceding gene: 116515054

Following gene: 116515056

Centisome position: 31.29

GC content: 20.56

Gene sequence:

>1221_bases
ATGAAAAAAAAATTGATTTTAGTATTAAATTGTGGAAGTTCTTCAGTAAAATTTTCTATCATTGATGTAATTGAAGGAGT
TTTATATATTTCAGGAATTGCAAATACTATAAATAATGTATCTTTTTTAAAGATTTATGATATTAAAAAAAAAATAAAAA
TTGTAAAAAAAAATATATCTACTGATTCATATAAAAAATTAATATTATTAATTTGTGATCTTTTGTTTATTCACTTTAAT
AAATATTTAAAATTAATTATAGGTATTGGTCATAGAATTGTACATGGAGGAAAAGACATAAAAAAATCTATGATTATTAA
TAAAAAAATTTTATTAAAAATTAAAAAATCAGCTATTTTTGCACCTCTTCATAATCCATATCATTTAATTGCAATAAAAA
TAATTTTAAATAAATTTGTAAAGTTAAAAAATAGAAATGTTGCTGTGTTTGATACTTCTTTTCATCAAACAATGCCTAAA
AAATCTTTTTTATATGGTATTCCATATTCTTTTTATAAAAAATATTCTATCCGTAAATATGGTGCTCATGGAATTAATCA
CTTTTATATAACACACGAATGTTCTTTATTTTTAAAAAAATCTACTAATAATTTAAATATTATTAGTTGTCATTTAGGTA
GTGGTTCTTCTATTACTGCTATAGTAAATGGTAAATCTATTGATACTTCTATGGGTCTAACTCCTTTAGAAGGATTAGTA
ATGGGAACAAGATGTGGTGACATTGATCCGTATATCATAATATATATGATTAAAAAATTAAATTTTTCAATAACTCAAAT
ACAAAAAATATTAACTAAAAGTTCTGGAGTATTAGGAATTAGTAGTATAACAAGTGATTTCAGAGAATTAGAAAAAAAAT
ATTATAGCCATAAAAAAGCAAAATTAGCAATTGATATTTTTTGTCGTCGAGTATCAAAGTATATTGCTGGATATTCATCA
TTAATGCCTAAAGGAAAATTAGATGCTATTGTATTTACTGGTGGTATTGGAGAAAATTCTAGTTTTATTCGAAAAAAAAT
CATAAAAAATTTATCTATTATAGGATTTTTTTTAGATATTGAAAAAAATTTAATTAAAACAGGAAATAATAATAGATTTA
TACATACTATAAATAGTAAACCTATATTAGTAATACCAGCAGATGAAAATAAAATTATCGCTAAAGAAACATATAATATT
TTAATAAAAAATAATTTTTAA

Upstream 100 bases:

>100_bases
ATATTTATTAATATGATTTTATTTTAAAATATTAATATAATATTTATTATAAATTTTATTTACTATTTTTCTACTTCCTT
CTATATTTTTAGAGATATTT

Downstream 100 bases:

>100_bases
TTTTATTAATATATAAATATTTAATAATTATAGTAAAAATTTTTTTACACAAAATTATTTATACTAATTTAACTTTATGA
AACTACTTTTATGAAAAAAT

Product: AckA

Products: NA

Alternate protein names: Acetokinase

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MKKKLILVLNCGSSSVKFSIIDVIEGVLYISGIANTINNVSFLKIYDIKKKIKIVKKNISTDSYKKLILLICDLLFIHFN
KYLKLIIGIGHRIVHGGKDIKKSMIINKKILLKIKKSAIFAPLHNPYHLIAIKIILNKFVKLKNRNVAVFDTSFHQTMPK
KSFLYGIPYSFYKKYSIRKYGAHGINHFYITHECSLFLKKSTNNLNIISCHLGSGSSITAIVNGKSIDTSMGLTPLEGLV
MGTRCGDIDPYIIIYMIKKLNFSITQIQKILTKSSGVLGISSITSDFRELEKKYYSHKKAKLAIDIFCRRVSKYIAGYSS
LMPKGKLDAIVFTGGIGENSSFIRKKIIKNLSIIGFFLDIEKNLIKTGNNNRFIHTINSKPILVIPADENKIIAKETYNI
LIKNNF

Sequences:

>Translated_406_residues
MKKKLILVLNCGSSSVKFSIIDVIEGVLYISGIANTINNVSFLKIYDIKKKIKIVKKNISTDSYKKLILLICDLLFIHFN
KYLKLIIGIGHRIVHGGKDIKKSMIINKKILLKIKKSAIFAPLHNPYHLIAIKIILNKFVKLKNRNVAVFDTSFHQTMPK
KSFLYGIPYSFYKKYSIRKYGAHGINHFYITHECSLFLKKSTNNLNIISCHLGSGSSITAIVNGKSIDTSMGLTPLEGLV
MGTRCGDIDPYIIIYMIKKLNFSITQIQKILTKSSGVLGISSITSDFRELEKKYYSHKKAKLAIDIFCRRVSKYIAGYSS
LMPKGKLDAIVFTGGIGENSSFIRKKIIKNLSIIGFFLDIEKNLIKTGNNNRFIHTINSKPILVIPADENKIIAKETYNI
LIKNNF
>Mature_406_residues
MKKKLILVLNCGSSSVKFSIIDVIEGVLYISGIANTINNVSFLKIYDIKKKIKIVKKNISTDSYKKLILLICDLLFIHFN
KYLKLIIGIGHRIVHGGKDIKKSMIINKKILLKIKKSAIFAPLHNPYHLIAIKIILNKFVKLKNRNVAVFDTSFHQTMPK
KSFLYGIPYSFYKKYSIRKYGAHGINHFYITHECSLFLKKSTNNLNIISCHLGSGSSITAIVNGKSIDTSMGLTPLEGLV
MGTRCGDIDPYIIIYMIKKLNFSITQIQKILTKSSGVLGISSITSDFRELEKKYYSHKKAKLAIDIFCRRVSKYIAGYSS
LMPKGKLDAIVFTGGIGENSSFIRKKIIKNLSIIGFFLDIEKNLIKTGNNNRFIHTINSKPILVIPADENKIIAKETYNI
LIKNNF

Specific function: Involved In The Activation Of Acetate To Acetyl CoA And The Secretion Of Acetate. During Anaerobic Growth Of The Organism, This Enzyme Is Also Involved In The Synthesis Of Most Of The ATP Formed Catabolically. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family

Homologues:

Organism=Escherichia coli, GI1788633, Length=400, Percent_Identity=47.25, Blast_Score=398, Evalue=1e-112,
Organism=Escherichia coli, GI145693184, Length=394, Percent_Identity=39.0862944162437, Blast_Score=300, Evalue=9e-83,

Paralogues:

None

Copy number: 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ACKA_BUCCC (Q057V8)

Other databases:

- EMBL:   CP000263
- RefSeq:   YP_802684.1
- ProteinModelPortal:   Q057V8
- SMR:   Q057V8
- STRING:   Q057V8
- EnsemblBacteria:   EBBUCT00000001416
- GeneID:   4440824
- GenomeReviews:   CP000263_GR
- KEGG:   bcc:BCc_114
- eggNOG:   COG0282
- GeneTree:   EBGT00050000008196
- HOGENOM:   HBG285863
- OMA:   KENHIRR
- BioCyc:   BAPH372461:BCC_114-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00020
- InterPro:   IPR000890
- InterPro:   IPR004372
- PANTHER:   PTHR21060
- PANTHER:   PTHR21060:SF11
- PIRSF:   PIRSF000722
- PRINTS:   PR00471
- TIGRFAMs:   TIGR00016

Pfam domain/function: PF00871 Acetate_kinase

EC number: =2.7.2.1

Molecular weight: Translated: 45882; Mature: 45882

Theoretical pI: Translated: 10.59; Mature: 10.59

Prosite motif: PS01075 ACETATE_KINASE_1; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKLILVLNCGSSSVKFSIIDVIEGVLYISGIANTINNVSFLKIYDIKKKIKIVKKNIS
CCCEEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHCCEEEEEEEEHHHHHHHHHHCCC
TDSYKKLILLICDLLFIHFNKYLKLIIGIGHRIVHGGKDIKKSMIINKKILLKIKKSAIF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCHHHHHHHHHCHHHEEEEECCEEE
APLHNPYHLIAIKIILNKFVKLKNRNVAVFDTSFHQTMPKKSFLYGIPYSFYKKYSIRKY
EECCCCHHHHHHHHHHHHHHHHCCCCEEEEECHHHHCCCCCCEEECCCHHHHHHCCCCCC
GAHGINHFYITHECSLFLKKSTNNLNIISCHLGSGSSITAIVNGKSIDTSMGLTPLEGLV
CCCCCEEEEEEEEEEEEEEECCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCCCHHHEE
MGTRCGDIDPYIIIYMIKKLNFSITQIQKILTKSSGVLGISSITSDFRELEKKYYSHKKA
EECCCCCCCCEEEEEEHHHCCCCHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCCCHH
KLAIDIFCRRVSKYIAGYSSLMPKGKLDAIVFTGGIGENSSFIRKKIIKNLSIIGFFLDI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHCCEEEEEEEEE
EKNLIKTGNNNRFIHTINSKPILVIPADENKIIAKETYNILIKNNF
HHHHHHCCCCCEEEEEECCCEEEEEECCCCCEEEEEEEEEEEEECC
>Mature Secondary Structure
MKKKLILVLNCGSSSVKFSIIDVIEGVLYISGIANTINNVSFLKIYDIKKKIKIVKKNIS
CCCEEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHCCEEEEEEEEHHHHHHHHHHCCC
TDSYKKLILLICDLLFIHFNKYLKLIIGIGHRIVHGGKDIKKSMIINKKILLKIKKSAIF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCHHHHHHHHHCHHHEEEEECCEEE
APLHNPYHLIAIKIILNKFVKLKNRNVAVFDTSFHQTMPKKSFLYGIPYSFYKKYSIRKY
EECCCCHHHHHHHHHHHHHHHHCCCCEEEEECHHHHCCCCCCEEECCCHHHHHHCCCCCC
GAHGINHFYITHECSLFLKKSTNNLNIISCHLGSGSSITAIVNGKSIDTSMGLTPLEGLV
CCCCCEEEEEEEEEEEEEEECCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCCCHHHEE
MGTRCGDIDPYIIIYMIKKLNFSITQIQKILTKSSGVLGISSITSDFRELEKKYYSHKKA
EECCCCCCCCEEEEEEHHHCCCCHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCCCHH
KLAIDIFCRRVSKYIAGYSSLMPKGKLDAIVFTGGIGENSSFIRKKIIKNLSIIGFFLDI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHCCEEEEEEEEE
EKNLIKTGNNNRFIHTINSKPILVIPADENKIIAKETYNILIKNNF
HHHHHHCCCCCEEEEEECCCEEEEEECCCCCEEEEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA