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The map label for this gene is ptsG [H]

Identifier: 116493542

GI number: 116493542

Start: 1795268

End: 1797247

Strand: Reverse

Name: ptsG [H]

Synonym: PEPE_1816

Alternate gene names: 116493542

Gene position: 1797247-1795268 (Counterclockwise)

Preceding gene: 116493543

Following gene: 116493541

Centisome position: 98.08

GC content: 41.06

Gene sequence:

>1980_bases
ATGAAAGCATATTTGCAACGCATGGGTCGTTCTTTACAACTTCCCGTAGCCGTTTTGCCTGCCGCCGCTTTGTTGGTTGG
TATTGGTAACTGGTGGGCTTCTTACAGTAATGACGTAGTTGCTCATTTCTTACAAGCCGGTGGTAACGCTGTTTTAGGTC
AACTACCGCTATTATTTGCCGTTGGTTTAGCCCTCGGGATGTCTGTCGATCAATCTGGGGCTGCTGCCCTCGCTGGGTTA
GTTGCCTTTGAGCTACCGGTCAATGTATTAAAGCCTGAATCGGTTGCTACATTAATGAACATCAAACCTACAGCCGTTGA
TGCTTCGTTTGCTCAAATTGGAAATGTATTTATCGGTATTATCGCTGGTTTGATTGCTGCAGCATTATACAATCGATTCC
ACGAAACAAAATTACCGATGGCTCTTTCCTTCTTTAGTGGTAAGCGTTTAGTACCAATTATGGCTGCCCTTGTTATGCTA
CTTGTCAGTGTAGTGTTACTATTTGTTTGGCCACCAGTTTACGGCGCTCTCGTTGCGTTTGCTAAGTTTATCTTGAACTT
AGGCTGGGTTGGTGCTGGATTGTACGGTTTCTTCAACCGTCTCCTTATCCCAACTGGTTTACATCAAGCTTTGAATTCCG
TATTCTGGTTTGACGTGGCTGGGATTAATGATATTGGTAAATTCTTGGCTTCTCAAGGTACAAAGGGTGTTACAGGTATG
TACCAAGCTGGATTCTTCCCAATCATGATGTTTGGACTTCCAGCCGGAGCTTACGCTATTTACAAAAATGCTCGTCCTGA
AAACAAAGCAACTACAGCATCATTGATGTTAGCTGCTGCATTTGCTTCATTCTTCACCGGTGTTACAGAACCACTTGAAT
TCTCATTTATGTTTGTTGCATGGCCTCTATACGTATTGCACGCAATCTTTACTGGTCTTTCACTCGCATTTGCGGCATTT
ATGCATTGGACAGCTGGTTTTGCATTCAGTGCCGGTTTAGTTGATTATGTGCTTAGTTTGAAGAACCCGATCGCTAACCA
ACCATTATGGTTAATTGTTCAAGGCCTCGTAATGGCTGTAATTTACTATTTTGGTTTCGATTTTGCGATTAAGAAATTCC
ATTTGATGACCCCAGGTCGCGAAGAATTAGCTGAGGACGATGGTGTTGAAGAAGTTGCAACTAATGATTCAGATGATAAG
TATACTGTTCAAGCTAAAAAGATCTACGCTGCTCTAGGCGGTTCAGACAACTTACAAGTCGTGGACAACTGTACAACACG
TCTTCGTCTTAAATTGAATGATACAGATAATATTAATGAAAATGCAATCAAACGCAGTGGTGCTGCAGGATTGAATAAGA
TTGATAAGAATAATCTACAAATTATTATTGGTACTGAAGTTCAATTCGTTTCAGATGCACTTGCAAAATTAGAGAATGCT
AAGGCCCCAATTTCTTCAGTGAAGACTGCTGATGAAACAGCTTCAACAGAAGAAACGGTTGCTGATGGTATTAAACGGGA
TGTTACGGAAGAGTTCTATAGTGTTGCTAATGGACAATACATGGATATTGAGGAAGTTCCTGATGACACGTTTGCTCAAA
AGATGTTGGGTGACGGATATGCTATTAATCCTACTGATGGAACGATTACTGCTCCAGTTGATGGAACAATTACATCAGTA
TTCCCTACTAAACATGCAATTGGTTTCAAGACAGATGCTGGTTTAGAAATCCTTCTTCATATGGGAATCGACACTGTTGA
ATTAAATGGTGCTCCATTCGATGTTAAGGTAGAAGATGGACAAACGGTTAAACATGGTGACGTTGTAGCTAAAGTTGACT
TAGACGCAATTAAAAATGCGGGTAAGCAGACACCAATGATCGTCATCGTTACGAACATGGATGCAGTTCGGGTGATGAAG
TTCAAAGGTAATGCATTAGTTACACCAGAATCCTTAGTTCTTAAAACAACTACTAAGTAA

Upstream 100 bases:

>100_bases
AAAGCGGATTATACCAATAATTTACGCTTGAAATAGCGTTTCCACTAACATAGAATTGGATTATCGCATTTATTCAATAT
TCTATTTGGAGGTATTATTC

Downstream 100 bases:

>100_bases
AATAAGTGAAGCAAAATCCTCTAAATCAACTACAATTGATTTGGGGGATTTTGTTTTCTAATAAAATTGGAGGTAGGGTA
GGATAGCATGGTTGAAAAAG

Product: N-acetylglucosamine and glucose PTS, EIICBA

Products: NA

Alternate protein names: EII-Glc/EIII-Glc; EIICBA-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component; Glucose-specific phosphotransferase enzyme IIA component; PTS system glucose-specific EIIA component [H]

Number of amino acids: Translated: 659; Mature: 659

Protein sequence:

>659_residues
MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDVVAHFLQAGGNAVLGQLPLLFAVGLALGMSVDQSGAAALAGL
VAFELPVNVLKPESVATLMNIKPTAVDASFAQIGNVFIGIIAGLIAAALYNRFHETKLPMALSFFSGKRLVPIMAALVML
LVSVVLLFVWPPVYGALVAFAKFILNLGWVGAGLYGFFNRLLIPTGLHQALNSVFWFDVAGINDIGKFLASQGTKGVTGM
YQAGFFPIMMFGLPAGAYAIYKNARPENKATTASLMLAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGLSLAFAAF
MHWTAGFAFSAGLVDYVLSLKNPIANQPLWLIVQGLVMAVIYYFGFDFAIKKFHLMTPGREELAEDDGVEEVATNDSDDK
YTVQAKKIYAALGGSDNLQVVDNCTTRLRLKLNDTDNINENAIKRSGAAGLNKIDKNNLQIIIGTEVQFVSDALAKLENA
KAPISSVKTADETASTEETVADGIKRDVTEEFYSVANGQYMDIEEVPDDTFAQKMLGDGYAINPTDGTITAPVDGTITSV
FPTKHAIGFKTDAGLEILLHMGIDTVELNGAPFDVKVEDGQTVKHGDVVAKVDLDAIKNAGKQTPMIVIVTNMDAVRVMK
FKGNALVTPESLVLKTTTK

Sequences:

>Translated_659_residues
MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDVVAHFLQAGGNAVLGQLPLLFAVGLALGMSVDQSGAAALAGL
VAFELPVNVLKPESVATLMNIKPTAVDASFAQIGNVFIGIIAGLIAAALYNRFHETKLPMALSFFSGKRLVPIMAALVML
LVSVVLLFVWPPVYGALVAFAKFILNLGWVGAGLYGFFNRLLIPTGLHQALNSVFWFDVAGINDIGKFLASQGTKGVTGM
YQAGFFPIMMFGLPAGAYAIYKNARPENKATTASLMLAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGLSLAFAAF
MHWTAGFAFSAGLVDYVLSLKNPIANQPLWLIVQGLVMAVIYYFGFDFAIKKFHLMTPGREELAEDDGVEEVATNDSDDK
YTVQAKKIYAALGGSDNLQVVDNCTTRLRLKLNDTDNINENAIKRSGAAGLNKIDKNNLQIIIGTEVQFVSDALAKLENA
KAPISSVKTADETASTEETVADGIKRDVTEEFYSVANGQYMDIEEVPDDTFAQKMLGDGYAINPTDGTITAPVDGTITSV
FPTKHAIGFKTDAGLEILLHMGIDTVELNGAPFDVKVEDGQTVKHGDVVAKVDLDAIKNAGKQTPMIVIVTNMDAVRVMK
FKGNALVTPESLVLKTTTK
>Mature_659_residues
MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDVVAHFLQAGGNAVLGQLPLLFAVGLALGMSVDQSGAAALAGL
VAFELPVNVLKPESVATLMNIKPTAVDASFAQIGNVFIGIIAGLIAAALYNRFHETKLPMALSFFSGKRLVPIMAALVML
LVSVVLLFVWPPVYGALVAFAKFILNLGWVGAGLYGFFNRLLIPTGLHQALNSVFWFDVAGINDIGKFLASQGTKGVTGM
YQAGFFPIMMFGLPAGAYAIYKNARPENKATTASLMLAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGLSLAFAAF
MHWTAGFAFSAGLVDYVLSLKNPIANQPLWLIVQGLVMAVIYYFGFDFAIKKFHLMTPGREELAEDDGVEEVATNDSDDK
YTVQAKKIYAALGGSDNLQVVDNCTTRLRLKLNDTDNINENAIKRSGAAGLNKIDKNNLQIIIGTEVQFVSDALAKLENA
KAPISSVKTADETASTEETVADGIKRDVTEEFYSVANGQYMDIEEVPDDTFAQKMLGDGYAINPTDGTITAPVDGTITSV
FPTKHAIGFKTDAGLEILLHMGIDTVELNGAPFDVKVEDGQTVKHGDVVAKVDLDAIKNAGKQTPMIVIVTNMDAVRVMK
FKGNALVTPESLVLKTTTK

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786894, Length=646, Percent_Identity=40.7120743034056, Blast_Score=424, Evalue=1e-120,
Organism=Escherichia coli, GI1787343, Length=477, Percent_Identity=39.2033542976939, Blast_Score=296, Evalue=4e-81,
Organism=Escherichia coli, GI1787908, Length=531, Percent_Identity=32.391713747646, Blast_Score=248, Evalue=9e-67,
Organism=Escherichia coli, GI1788757, Length=149, Percent_Identity=42.9530201342282, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1790159, Length=121, Percent_Identity=42.9752066115703, Blast_Score=98, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 70763; Mature: 70763

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00371 PTS_EIIA_TYPE_1_HIS ; PS51093 PTS_EIIA_TYPE_1 ; PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDVVAHFLQAGGNAVLGQLPLLFA
CCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHH
VGLALGMSVDQSGAAALAGLVAFELPVNVLKPESVATLMNIKPTAVDASFAQIGNVFIGI
HHHHHCCCCCCCHHHHHHHHHHHHCCCHHCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHH
IAGLIAAALYNRFHETKLPMALSFFSGKRLVPIMAALVMLLVSVVLLFVWPPVYGALVAF
HHHHHHHHHHHHHHHCCCCCEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKFILNLGWVGAGLYGFFNRLLIPTGLHQALNSVFWFDVAGINDIGKFLASQGTKGVTGM
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEEECCHHHHHHHHHCCCCCCCCHH
YQAGFFPIMMFGLPAGAYAIYKNARPENKATTASLMLAAAFASFFTGVTEPLEFSFMFVA
HHHCHHHHHHHHCCCCHHHEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
WPLYVLHAIFTGLSLAFAAFMHWTAGFAFSAGLVDYVLSLKNPIANQPLWLIVQGLVMAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
IYYFGFDFAIKKFHLMTPGREELAEDDGVEEVATNDSDDKYTVQAKKIYAALGGSDNLQV
HHHHHHHHHHHEEEECCCCHHHHHCCCCCHHHHCCCCCCEEEEEHHHHHHCCCCCCCEEE
VDNCTTRLRLKLNDTDNINENAIKRSGAAGLNKIDKNNLQIIIGTEVQFVSDALAKLENA
EECCCEEEEEEECCCCCCCHHHHHHCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCC
KAPISSVKTADETASTEETVADGIKRDVTEEFYSVANGQYMDIEEVPDDTFAQKMLGDGY
CCCHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHCCCHHHHHHHHCCCE
AINPTDGTITAPVDGTITSVFPTKHAIGFKTDAGLEILLHMGIDTVELNGAPFDVKVEDG
EECCCCCEEECCCCCCEEEECCCCCCCCCCCCCCHHHHEECCCCEEEECCCCEEEEECCC
QTVKHGDVVAKVDLDAIKNAGKQTPMIVIVTNMDAVRVMKFKGNALVTPESLVLKTTTK
CEEECCCEEEEEEHHHHHCCCCCCCEEEEEECCCEEEEEEECCCEEECCCCEEEEECCC
>Mature Secondary Structure
MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDVVAHFLQAGGNAVLGQLPLLFA
CCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHH
VGLALGMSVDQSGAAALAGLVAFELPVNVLKPESVATLMNIKPTAVDASFAQIGNVFIGI
HHHHHCCCCCCCHHHHHHHHHHHHCCCHHCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHH
IAGLIAAALYNRFHETKLPMALSFFSGKRLVPIMAALVMLLVSVVLLFVWPPVYGALVAF
HHHHHHHHHHHHHHHCCCCCEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKFILNLGWVGAGLYGFFNRLLIPTGLHQALNSVFWFDVAGINDIGKFLASQGTKGVTGM
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEEECCHHHHHHHHHCCCCCCCCHH
YQAGFFPIMMFGLPAGAYAIYKNARPENKATTASLMLAAAFASFFTGVTEPLEFSFMFVA
HHHCHHHHHHHHCCCCHHHEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
WPLYVLHAIFTGLSLAFAAFMHWTAGFAFSAGLVDYVLSLKNPIANQPLWLIVQGLVMAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
IYYFGFDFAIKKFHLMTPGREELAEDDGVEEVATNDSDDKYTVQAKKIYAALGGSDNLQV
HHHHHHHHHHHEEEECCCCHHHHHCCCCCHHHHCCCCCCEEEEEHHHHHHCCCCCCCEEE
VDNCTTRLRLKLNDTDNINENAIKRSGAAGLNKIDKNNLQIIIGTEVQFVSDALAKLENA
EECCCEEEEEEECCCCCCCHHHHHHCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCC
KAPISSVKTADETASTEETVADGIKRDVTEEFYSVANGQYMDIEEVPDDTFAQKMLGDGY
CCCHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHCCCHHHHHHHHCCCE
AINPTDGTITAPVDGTITSVFPTKHAIGFKTDAGLEILLHMGIDTVELNGAPFDVKVEDG
EECCCCCEEECCCCCCEEEECCCCCCCCCCCCCCHHHHEECCCCEEEECCCCEEEEECCC
QTVKHGDVVAKVDLDAIKNAGKQTPMIVIVTNMDAVRVMKFKGNALVTPESLVLKTTTK
CEEECCCEEEEEEHHHHHCCCCCCCEEEEEECCCEEEEEEECCCEEECCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1508157; 9384377; 2497294; 2120236; 1911744; 1906345; 9593197 [H]