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The map label for this gene is paiA [H]

Identifier: 116493405

GI number: 116493405

Start: 1657146

End: 1657661

Strand: Reverse

Name: paiA [H]

Synonym: PEPE_1677

Alternate gene names: 116493405

Gene position: 1657661-1657146 (Counterclockwise)

Preceding gene: 116493406

Following gene: 116493403

Centisome position: 90.46

GC content: 36.63

Gene sequence:

>516_bases
ATGACAATTGATATTCAAAAAGTACGAGTTGAAGAAGTAGAAGCGTTACAAAAGATAAGTATTGAGACTTTTGGAGATAC
TTTTGGCGCAGATAACAGTTCTGAAGATCTAGACCAATACTATCAAAAAGCGTACAATTTCAAACAGTTAACTTCAGAGA
TTATTAATGGTGCATCTTACTTCTTTTTTGCCAAGCAAGCTGATCAGCTTCTAGGGTATTTAAAAGTCAACATAGATGAA
GCTCAGTCAGAAAAAATGGGGTCCGACACTTTGGAAGTTGAGCGGATTTACGTGCGTCAGCAATTTAAACGTCGGGGAGT
TGGCTCTAGATTAATGCAACAGGCACTTGAGGTTGCACAAGAAAACCACAAACGTAAAGTCTGGTTAGGAGTTTGGGAGC
ATAACGAAGCTGCTAAGAAATTTTACCAAACTCAAGGATTTAACCAAGTTGGAGAACATGTTTTTCAATTAGGTAACGAT
TTGCAACGTGATTTAATTATGCTAAAAGATATTTAA

Upstream 100 bases:

>100_bases
ACAGCATTGAAAGCAATGCTGGAGAAAGTTGAACGAAATGTTAGTATCGACTGGAACTATGTAAAAAGTGGTCATCATAG
AAAATATTGAGGTGAATTGA

Downstream 100 bases:

>100_bases
TGGAGGAGCCCCCTAAAATGGATGGGCTTTTTTGTTTGGAATAAACTGGTGATAAATTAAAAAACTAGCAAATTAATGCT
AGCTCTCCAAAACTAAATAA

Product: spermine/spermidine N-acetyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MTIDIQKVRVEEVEALQKISIETFGDTFGADNSSEDLDQYYQKAYNFKQLTSEIINGASYFFFAKQADQLLGYLKVNIDE
AQSEKMGSDTLEVERIYVRQQFKRRGVGSRLMQQALEVAQENHKRKVWLGVWEHNEAAKKFYQTQGFNQVGEHVFQLGND
LQRDLIMLKDI

Sequences:

>Translated_171_residues
MTIDIQKVRVEEVEALQKISIETFGDTFGADNSSEDLDQYYQKAYNFKQLTSEIINGASYFFFAKQADQLLGYLKVNIDE
AQSEKMGSDTLEVERIYVRQQFKRRGVGSRLMQQALEVAQENHKRKVWLGVWEHNEAAKKFYQTQGFNQVGEHVFQLGND
LQRDLIMLKDI
>Mature_170_residues
TIDIQKVRVEEVEALQKISIETFGDTFGADNSSEDLDQYYQKAYNFKQLTSEIINGASYFFFAKQADQLLGYLKVNIDEA
QSEKMGSDTLEVERIYVRQQFKRRGVGSRLMQQALEVAQENHKRKVWLGVWEHNEAAKKFYQTQGFNQVGEHVFQLGNDL
QRDLIMLKDI

Specific function: Possesses N1-acetyltransferase activity toward polyamine substrates including spermidine and spermine. Can acetylate both spermidine and spermine. In this way it may function in regulating intracellular polyamine concentrations and/or binding capabilities

COG id: COG0454

COG function: function code KR; Histone acetyltransferase HPA2 and related acetyltransferases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181 [H]

Pfam domain/function: PF00583 Acetyltransf_1 [H]

EC number: NA

Molecular weight: Translated: 19897; Mature: 19765

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIDIQKVRVEEVEALQKISIETFGDTFGADNSSEDLDQYYQKAYNFKQLTSEIINGASY
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHH
FFFAKQADQLLGYLKVNIDEAQSEKMGSDTLEVERIYVRQQFKRRGVGSRLMQQALEVAQ
HHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
ENHKRKVWLGVWEHNEAAKKFYQTQGFNQVGEHVFQLGNDLQRDLIMLKDI
HCCCCEEEEEEECCCHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHCCC
>Mature Secondary Structure 
TIDIQKVRVEEVEALQKISIETFGDTFGADNSSEDLDQYYQKAYNFKQLTSEIINGASY
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHH
FFFAKQADQLLGYLKVNIDEAQSEKMGSDTLEVERIYVRQQFKRRGVGSRLMQQALEVAQ
HHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
ENHKRKVWLGVWEHNEAAKKFYQTQGFNQVGEHVFQLGNDLQRDLIMLKDI
HCCCCEEEEEEECCCHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2108124; 9384377 [H]