Click here to switch to the map view.

The map label for this gene is dhaK [H]

Identifier: 116493390

GI number: 116493390

Start: 1649233

End: 1650225

Strand: Reverse

Name: dhaK [H]

Synonym: PEPE_1662

Alternate gene names: 116493390

Gene position: 1650225-1649233 (Counterclockwise)

Preceding gene: 116493395

Following gene: 116493389

Centisome position: 90.06

GC content: 40.28

Gene sequence:

>993_bases
ATGAAAAAAATCATTAATGATCCAAAGAATGTTGTCGATGAAATGGTTCAAGGATTGGTAAGAAGTTACCCCGAATATTT
AGAAAGAATTCCAGAAACAGGTGTAGTTTATCGTCATGACTTAAAAAATATCCAAGGTCAAGTTGGAATTGTGAGTGGCG
GTGGAAGTGGTCACGAACCCACTCATGCTGGGTTTGTAGGCGATGGAATGTTGAGTGCGGCGGTTTGTGGGGAAGTGTTT
ACGTCACCAACTCCAGATCAAATCTTTGAAGCAATCAAGAAAGTTGATTCGGGAGCCGGTGTATTCTTAGTAATTAAAAA
TTATTCTGGAGATGTCATGAATTTTGAAATGGCTCAAGACATGGCTGAAATGGAAGATATTAAAGTTAAATCGATAGTTG
TTGATGATGATATTGCGGTAGAAAACAGTACTTATACCCAAGGACGCCGTGGCGTCGCAGGGACCATCTTCATGCACAAA
GTTTTAGGTGCGGCCGCAGCTAAAGGAGCCAATCTAGACGAACTAGAACAATTAGCCCAAAAAGTTTTGCCTAATATCAA
GACGATTGCAGTCGCTTTAAGTGGTGCAACTGTTCCAGAAGTAGGTAAACCTGGATTTACACTGGGTGAAGATGAAATTG
AATACGGTGTAGGTATTCATGGTGAGCCAGGCTATCGGCGGGAAAAGTTACAACCTTCCAAGGCCTTAGTAGAAGAATTG
GTTGGAAAATTGAATCAAGAGTTCAAATTCGAAAAGGGCGATCAAGTAGCCGTTTTAGTTAATGGAATGGGAGCTACCCC
ACTCATGGAGCAGTATATCTTCATGAACGATGTTTTAAATAAATTAGCTGATTTAGGTTTGGAAGTTAAATTCACCAAGG
TAGGTAGTTTAATGACTTCGCTTGAAATGGCCGGAATTTCACTAACCTTGTTTAAGGTATCCGACGAAATTGTTGAAAAC
CTAAATTACGCCACAGATACCATTGCTTGGTAA

Upstream 100 bases:

>100_bases
TTATTTTTATTAAACTTTTTAGGCTTTATTCTTGTGATTGTAATCGCTTTCTACTATGCTTTAATTGTACGAAAAAAGTT
ACCGAGGGGGAAATGTTTTC

Downstream 100 bases:

>100_bases
TTTTAATTAGGATGGAGAGAAATAGTATGTTAGATGTTGAAAATGTAAAAAGCTGGATGACCAAATTTAACGAACAAATT
CAAGCTCACCACGATTATCT

Product: dihydroxyacetone kinase subunit DhaK

Products: ADP; glycerone phosphate

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MKKIINDPKNVVDEMVQGLVRSYPEYLERIPETGVVYRHDLKNIQGQVGIVSGGGSGHEPTHAGFVGDGMLSAAVCGEVF
TSPTPDQIFEAIKKVDSGAGVFLVIKNYSGDVMNFEMAQDMAEMEDIKVKSIVVDDDIAVENSTYTQGRRGVAGTIFMHK
VLGAAAAKGANLDELEQLAQKVLPNIKTIAVALSGATVPEVGKPGFTLGEDEIEYGVGIHGEPGYRREKLQPSKALVEEL
VGKLNQEFKFEKGDQVAVLVNGMGATPLMEQYIFMNDVLNKLADLGLEVKFTKVGSLMTSLEMAGISLTLFKVSDEIVEN
LNYATDTIAW

Sequences:

>Translated_330_residues
MKKIINDPKNVVDEMVQGLVRSYPEYLERIPETGVVYRHDLKNIQGQVGIVSGGGSGHEPTHAGFVGDGMLSAAVCGEVF
TSPTPDQIFEAIKKVDSGAGVFLVIKNYSGDVMNFEMAQDMAEMEDIKVKSIVVDDDIAVENSTYTQGRRGVAGTIFMHK
VLGAAAAKGANLDELEQLAQKVLPNIKTIAVALSGATVPEVGKPGFTLGEDEIEYGVGIHGEPGYRREKLQPSKALVEEL
VGKLNQEFKFEKGDQVAVLVNGMGATPLMEQYIFMNDVLNKLADLGLEVKFTKVGSLMTSLEMAGISLTLFKVSDEIVEN
LNYATDTIAW
>Mature_330_residues
MKKIINDPKNVVDEMVQGLVRSYPEYLERIPETGVVYRHDLKNIQGQVGIVSGGGSGHEPTHAGFVGDGMLSAAVCGEVF
TSPTPDQIFEAIKKVDSGAGVFLVIKNYSGDVMNFEMAQDMAEMEDIKVKSIVVDDDIAVENSTYTQGRRGVAGTIFMHK
VLGAAAAKGANLDELEQLAQKVLPNIKTIAVALSGATVPEVGKPGFTLGEDEIEYGVGIHGEPGYRREKLQPSKALVEEL
VGKLNQEFKFEKGDQVAVLVNGMGATPLMEQYIFMNDVLNKLADLGLEVKFTKVGSLMTSLEMAGISLTLFKVSDEIVEN
LNYATDTIAW

Specific function: Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone [H]

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaK domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=336, Percent_Identity=37.202380952381, Blast_Score=225, Evalue=4e-59,
Organism=Escherichia coli, GI87081857, Length=343, Percent_Identity=43.4402332361516, Blast_Score=288, Evalue=5e-79,
Organism=Caenorhabditis elegans, GI17565018, Length=330, Percent_Identity=33.9393939393939, Blast_Score=192, Evalue=3e-49,
Organism=Saccharomyces cerevisiae, GI6321055, Length=336, Percent_Identity=38.0952380952381, Blast_Score=195, Evalue=8e-51,
Organism=Saccharomyces cerevisiae, GI6323570, Length=333, Percent_Identity=34.8348348348348, Blast_Score=167, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004006
- InterPro:   IPR012736 [H]

Pfam domain/function: PF02733 Dak1 [H]

EC number: 2.7.1.29

Molecular weight: Translated: 35662; Mature: 35662

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIINDPKNVVDEMVQGLVRSYPEYLERIPETGVVYRHDLKNIQGQVGIVSGGGSGHEP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHCCCCCEEEEECCCCCCCC
THAGFVGDGMLSAAVCGEVFTSPTPDQIFEAIKKVDSGAGVFLVIKNYSGDVMNFEMAQD
CCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCEEEHHHHHH
MAEMEDIKVKSIVVDDDIAVENSTYTQGRRGVAGTIFMHKVLGAAAAKGANLDELEQLAQ
HHHHHHCEEEEEEECCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHH
KVLPNIKTIAVALSGATVPEVGKPGFTLGEDEIEYGVGIHGEPGYRREKLQPSKALVEEL
HHCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCHHHCCHHHHHHHHH
VGKLNQEFKFEKGDQVAVLVNGMGATPLMEQYIFMNDVLNKLADLGLEVKFTKVGSLMTS
HHHHCHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHH
LEMAGISLTLFKVSDEIVENLNYATDTIAW
HHHCCCEEEEEEHHHHHHHHCCCCHHHCCC
>Mature Secondary Structure
MKKIINDPKNVVDEMVQGLVRSYPEYLERIPETGVVYRHDLKNIQGQVGIVSGGGSGHEP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHCCCCCEEEEECCCCCCCC
THAGFVGDGMLSAAVCGEVFTSPTPDQIFEAIKKVDSGAGVFLVIKNYSGDVMNFEMAQD
CCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCEEEHHHHHH
MAEMEDIKVKSIVVDDDIAVENSTYTQGRRGVAGTIFMHKVLGAAAAKGANLDELEQLAQ
HHHHHHCEEEEEEECCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHH
KVLPNIKTIAVALSGATVPEVGKPGFTLGEDEIEYGVGIHGEPGYRREKLQPSKALVEEL
HHCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCHHHCCHHHHHHHHH
VGKLNQEFKFEKGDQVAVLVNGMGATPLMEQYIFMNDVLNKLADLGLEVKFTKVGSLMTS
HHHHCHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHH
LEMAGISLTLFKVSDEIVENLNYATDTIAW
HHHCCCEEEEEEHHHHHHHHCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; glycerone

Specific reaction: ATP + glycerone = ADP + glycerone phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]