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The map label for this gene is opuCB [H]

Identifier: 116493382

GI number: 116493382

Start: 1641185

End: 1641817

Strand: Reverse

Name: opuCB [H]

Synonym: PEPE_1654

Alternate gene names: 116493382

Gene position: 1641817-1641185 (Counterclockwise)

Preceding gene: 116493383

Following gene: 116493381

Centisome position: 89.6

GC content: 39.81

Gene sequence:

>633_bases
ATGATCAACTTCCTGAATCAATATGGAGGCGACATCTTAAGTAAAACGGGACAACATATTTATATTTCAGCTTTTGCTTT
AGCACTGGGAATAATTGTGGCAGTACCTTTGGGAATGCTTTTAATTCGGGCACCTAAAATCTCTGGTTTTGTTATTGGTT
TAGCCAGTGTGATGCAAACTATTCCTGCGCTGGCCTTGCTTGCAATGATGATTCCGATTTTTGGAATTGGGTCAACTCCA
GCCATCGTGGCGTTATTTATCTACTCATTACTTCCTATTTTAAGAAACACGTATCTGGGATTAGATAGTGTAGATCCAGC
GTTAGTGGATGCTGCTAAAGGGATGGGAATGAATAGTTTTCAACGATTGTGGAAAGTTGAATTGCAACTAGCATTACCAG
TAATTATGTCTGGAATTCGTTTATCAGCTACTTATGTAATCGCATGGACTGCTTTGGCATCTTATATCGGTGCTGGCGGT
TTGGGTGATTTGATTTTCAACGGTTTAAATCTATATCGTCCGGATTTAATCTTAGCGGGATCAATCCCTGTGATTATTTT
AGCTTTAGTCGCCGATTTATTACTTGGAAAATTGGAAGACAAATTAACCCCTCGAACACGGGAGGTGGGCTAA

Upstream 100 bases:

>100_bases
TTTATGATGCTTTATTTACAGATGATGGAATCACTACAGATAGCAGTACCGATGCTAGTTCAAAATCGGAGGAGCAAAAA
GAGAAAGATGGTGATCAATA

Downstream 100 bases:

>100_bases
ATGTTAAAAAGATTTCTTAAATTAATTTTGCCGTTGGGCGCATTAGCTGTAGTTCTTTCCGGTTGTGGCTGGCCAGGACT
TGGTGGTACGACTGGAAATA

Product: glycine betaine/carnitine/choline ABC transporter, permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MINFLNQYGGDILSKTGQHIYISAFALALGIIVAVPLGMLLIRAPKISGFVIGLASVMQTIPALALLAMMIPIFGIGSTP
AIVALFIYSLLPILRNTYLGLDSVDPALVDAAKGMGMNSFQRLWKVELQLALPVIMSGIRLSATYVIAWTALASYIGAGG
LGDLIFNGLNLYRPDLILAGSIPVIILALVADLLLGKLEDKLTPRTREVG

Sequences:

>Translated_210_residues
MINFLNQYGGDILSKTGQHIYISAFALALGIIVAVPLGMLLIRAPKISGFVIGLASVMQTIPALALLAMMIPIFGIGSTP
AIVALFIYSLLPILRNTYLGLDSVDPALVDAAKGMGMNSFQRLWKVELQLALPVIMSGIRLSATYVIAWTALASYIGAGG
LGDLIFNGLNLYRPDLILAGSIPVIILALVADLLLGKLEDKLTPRTREVG
>Mature_210_residues
MINFLNQYGGDILSKTGQHIYISAFALALGIIVAVPLGMLLIRAPKISGFVIGLASVMQTIPALALLAMMIPIFGIGSTP
AIVALFIYSLLPILRNTYLGLDSVDPALVDAAKGMGMNSFQRLWKVELQLALPVIMSGIRLSATYVIAWTALASYIGAGG
LGDLIFNGLNLYRPDLILAGSIPVIILALVADLLLGKLEDKLTPRTREVG

Specific function: Involved in a high affinity multicomponent binding- protein-dependent transport system for glycine betaine, carnitine and choline; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1174

COG function: function code E; ABC-type proline/glycine betaine transport systems, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788449, Length=154, Percent_Identity=40.2597402597403, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1788451, Length=194, Percent_Identity=35.0515463917526, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1789033, Length=164, Percent_Identity=35.3658536585366, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1786564, Length=199, Percent_Identity=30.1507537688442, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 22305; Mature: 22305

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINFLNQYGGDILSKTGQHIYISAFALALGIIVAVPLGMLLIRAPKISGFVIGLASVMQT
CCCCHHHHCCHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
IPALALLAMMIPIFGIGSTPAIVALFIYSLLPILRNTYLGLDSVDPALVDAAKGMGMNSF
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHH
QRLWKVELQLALPVIMSGIRLSATYVIAWTALASYIGAGGLGDLIFNGLNLYRPDLILAG
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCEEEEC
SIPVIILALVADLLLGKLEDKLTPRTREVG
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MINFLNQYGGDILSKTGQHIYISAFALALGIIVAVPLGMLLIRAPKISGFVIGLASVMQT
CCCCHHHHCCHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
IPALALLAMMIPIFGIGSTPAIVALFIYSLLPILRNTYLGLDSVDPALVDAAKGMGMNSF
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHH
QRLWKVELQLALPVIMSGIRLSATYVIAWTALASYIGAGGLGDLIFNGLNLYRPDLILAG
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCEEEEC
SIPVIILALVADLLLGKLEDKLTPRTREVG
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10216873; 9384377 [H]