Click here to switch to the map view.

The map label for this gene is prmA

Identifier: 116492885

GI number: 116492885

Start: 1122291

End: 1123241

Strand: Reverse

Name: prmA

Synonym: PEPE_1123

Alternate gene names: 116492885

Gene position: 1123241-1122291 (Counterclockwise)

Preceding gene: 116492886

Following gene: 116492884

Centisome position: 61.3

GC content: 38.28

Gene sequence:

>951_bases
TTGAAATGGACTGAAGTAAACGTCAAAACAACAAACGAGGCCGTCGAAGCTGTTAGCAGCATTTTCGATGGCCTCGATGC
TGTTGGAGTGAAAATTGAAAATGCACTAGATTTTGAGAATTATCGAGCTAGTAATCCTGCAGAATTAATGGAATTAAAAG
ATATTCCACATATTACTGAAGGTGCAATCGTATCAGCATACTATCCAGACGATACAACAAATATTGACGTAATTTTAAGT
CAATTACGTACTAAGGTGAATGCATTAGTTGACTTTGGACTTGATATTGGAGAAGCCAGCATTACGACGGTTGAAGTGCA
GGATGACAACTGGGCTACAGCATGGAAGAAGTATTATCATCCAGTCCGCATTACCCGTTATTTAACGGTAAAACCAAGTT
GGAGTGATTACCAAGCAAGTTTCAGCGATGAAAAGGTAATTAGCTTAGATCCAGGAATGGCTTTTGGCACGGGAACTCAT
CCCACAACTCGTCTTTGTCTCCAAGCTTTAGAAATGACGATGCGTGGCGGCGAGACACTTTATGATGTCGGAACTGGTTC
AGGAGTTTTAAGTATTGCTGCTAAACACTTAGGAGCAAGTGATGTAGAAGCTTTTGATGTCGATGATATTGCAGTCGCAG
CCGCTCAAGAAAACTTCGATTTAAATCCAATTGCTAAGGATATTAAAGTTAGTGCTAATGATTTATTGAAAGGGATTAAT
CGCCCTGTAGATACAATTGTTGCTAATATTTTATCCGATATTTTAGTACCATTGATTCCGCAAGCTAAGCAATTGCTTAA
TTCCAATGGATATTTCATATTATCAGGGATTATTGATGATAAACTAGAGTTAGTGATAGATACATTGATAGCCAATGATT
TTAAAATTGAAGAAGTTCTACATTACGGTGAGTGGCGTGGCGTGATTGCTACTAATCGGAAAGATGATTAA

Upstream 100 bases:

>100_bases
CCTAAACAAGCTTTAAGTGAAAAATAATTTACTTTTCGTATATTTAAGCAAAATGGTATCATAGTATCTAAACACGAGAT
ATTATAGGAGCTGATTTTGT

Downstream 100 bases:

>100_bases
GGAGAAACTATGCAAAGGTATTTTGTAAAACAGCCCCTTAAGATCCAAGCTGAACTTCAACTTTCGAAAGAAGATTCTCA
TCATCTGATTCGAGTAATGC

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MKWTEVNVKTTNEAVEAVSSIFDGLDAVGVKIENALDFENYRASNPAELMELKDIPHITEGAIVSAYYPDDTTNIDVILS
QLRTKVNALVDFGLDIGEASITTVEVQDDNWATAWKKYYHPVRITRYLTVKPSWSDYQASFSDEKVISLDPGMAFGTGTH
PTTRLCLQALEMTMRGGETLYDVGTGSGVLSIAAKHLGASDVEAFDVDDIAVAAAQENFDLNPIAKDIKVSANDLLKGIN
RPVDTIVANILSDILVPLIPQAKQLLNSNGYFILSGIIDDKLELVIDTLIANDFKIEEVLHYGEWRGVIATNRKDD

Sequences:

>Translated_316_residues
MKWTEVNVKTTNEAVEAVSSIFDGLDAVGVKIENALDFENYRASNPAELMELKDIPHITEGAIVSAYYPDDTTNIDVILS
QLRTKVNALVDFGLDIGEASITTVEVQDDNWATAWKKYYHPVRITRYLTVKPSWSDYQASFSDEKVISLDPGMAFGTGTH
PTTRLCLQALEMTMRGGETLYDVGTGSGVLSIAAKHLGASDVEAFDVDDIAVAAAQENFDLNPIAKDIKVSANDLLKGIN
RPVDTIVANILSDILVPLIPQAKQLLNSNGYFILSGIIDDKLELVIDTLIANDFKIEEVLHYGEWRGVIATNRKDD
>Mature_316_residues
MKWTEVNVKTTNEAVEAVSSIFDGLDAVGVKIENALDFENYRASNPAELMELKDIPHITEGAIVSAYYPDDTTNIDVILS
QLRTKVNALVDFGLDIGEASITTVEVQDDNWATAWKKYYHPVRITRYLTVKPSWSDYQASFSDEKVISLDPGMAFGTGTH
PTTRLCLQALEMTMRGGETLYDVGTGSGVLSIAAKHLGASDVEAFDVDDIAVAAAQENFDLNPIAKDIKVSANDLLKGIN
RPVDTIVANILSDILVPLIPQAKQLLNSNGYFILSGIIDDKLELVIDTLIANDFKIEEVLHYGEWRGVIATNRKDD

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=217, Percent_Identity=36.8663594470046, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_PEDPA (Q03F44)

Other databases:

- EMBL:   CP000422
- RefSeq:   YP_804620.1
- ProteinModelPortal:   Q03F44
- STRING:   Q03F44
- GeneID:   4417092
- GenomeReviews:   CP000422_GR
- KEGG:   ppe:PEPE_1123
- NMPDR:   fig|278197.10.peg.986
- eggNOG:   COG2264
- HOGENOM:   HBG584653
- OMA:   IELNPGM
- PhylomeDB:   Q03F44
- ProtClustDB:   PRK00517
- BioCyc:   PPEN278197:PEPE_1123-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 34696; Mature: 34696

Theoretical pI: Translated: 4.22; Mature: 4.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKWTEVNVKTTNEAVEAVSSIFDGLDAVGVKIENALDFENYRASNPAELMELKDIPHITE
CCEEEEEEEEHHHHHHHHHHHHCCHHHHCEEECCCCCCCCCCCCCHHHHHHHHCCCCCCC
GAIVSAYYPDDTTNIDVILSQLRTKVNALVDFGLDIGEASITTVEVQDDNWATAWKKYYH
CCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCHHHHHHHHCC
PVRITRYLTVKPSWSDYQASFSDEKVISLDPGMAFGTGTHPTTRLCLQALEMTMRGGETL
CEEEEEEEEECCCCCCCCCCCCCCEEEEECCCCEECCCCCHHHHHHHHHHHHHHCCCCEE
YDVGTGSGVLSIAAKHLGASDVEAFDVDDIAVAAAQENFDLNPIAKDIKVSANDLLKGIN
EECCCCCHHHHHHHHHCCCCCCCEECCCHHEEEECCCCCCCCCHHHHHCCCHHHHHHHCC
RPVDTIVANILSDILVPLIPQAKQLLNSNGYFILSGIIDDKLELVIDTLIANDFKIEEVL
CCHHHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCCCCCHHHHH
HYGEWRGVIATNRKDD
HHCCCCCEEECCCCCC
>Mature Secondary Structure
MKWTEVNVKTTNEAVEAVSSIFDGLDAVGVKIENALDFENYRASNPAELMELKDIPHITE
CCEEEEEEEEHHHHHHHHHHHHCCHHHHCEEECCCCCCCCCCCCCHHHHHHHHCCCCCCC
GAIVSAYYPDDTTNIDVILSQLRTKVNALVDFGLDIGEASITTVEVQDDNWATAWKKYYH
CCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCHHHHHHHHCC
PVRITRYLTVKPSWSDYQASFSDEKVISLDPGMAFGTGTHPTTRLCLQALEMTMRGGETL
CEEEEEEEEECCCCCCCCCCCCCCEEEEECCCCEECCCCCHHHHHHHHHHHHHHCCCCEE
YDVGTGSGVLSIAAKHLGASDVEAFDVDDIAVAAAQENFDLNPIAKDIKVSANDLLKGIN
EECCCCCHHHHHHHHHCCCCCCCEECCCHHEEEECCCCCCCCCHHHHHCCCHHHHHHHCC
RPVDTIVANILSDILVPLIPQAKQLLNSNGYFILSGIIDDKLELVIDTLIANDFKIEEVL
CCHHHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCCCCCHHHHH
HYGEWRGVIATNRKDD
HHCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA