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The map label for this gene is hit [H]

Identifier: 116492447

GI number: 116492447

Start: 719818

End: 720249

Strand: Reverse

Name: hit [H]

Synonym: PEPE_0679

Alternate gene names: 116492447

Gene position: 720249-719818 (Counterclockwise)

Preceding gene: 116492451

Following gene: 116492446

Centisome position: 39.31

GC content: 37.5

Gene sequence:

>432_bases
ATGGATGAAAATTGTGTATTTTGTAAAATAATTACTGGCGATATTCCTAGTTATACTGTATATGAAGATGACGTGGTTAA
AGCATTTCTTGATATTTCTCAAGTAACACCTGGACATACTTTGGTGGTACCTAAAAAACATGTTCCCGATCTTTTTGCCT
ATGATTCCCAGCTGGCAGCAGACGTCTTCTCCAGAATTCCTAAGATTGCGACGGCCATCAAGGCTAGCAATCCTGACATT
AAAGCCATGAATGTGATTAATAATAACGGCGAATTAGCCTATCAGAGTGTCTTCCACTCTCACTTCCATTTGATTCCACG
TTATACCAAGGATGATGGTTTCAGCATGACCTTTACTGATAACACCGATAAATACAGTTCTGAGGAACTTCAAAAAATCC
AAAAAAAGATTACTGATCGTTTAGGTGATTAA

Upstream 100 bases:

>100_bases
TCTCCATAAATTATAACATATCGGTCTTTAACCATATTGCTATGATGATACATTCCCTCCTTTTTCATGTATAATTAATT
ATAAATTGGAGGTAGAAATA

Downstream 100 bases:

>100_bases
TTATGGCAAAAAAAACTAAGAAGCATTCATGGTTAAAGTGGTCCATCGGAACTTGGGCTGGTTTTAAAGGTGTCGAATAT
CTTCTTAACCATCCCCATTT

Product: diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 143; Mature: 143

Protein sequence:

>143_residues
MDENCVFCKIITGDIPSYTVYEDDVVKAFLDISQVTPGHTLVVPKKHVPDLFAYDSQLAADVFSRIPKIATAIKASNPDI
KAMNVINNNGELAYQSVFHSHFHLIPRYTKDDGFSMTFTDNTDKYSSEELQKIQKKITDRLGD

Sequences:

>Translated_143_residues
MDENCVFCKIITGDIPSYTVYEDDVVKAFLDISQVTPGHTLVVPKKHVPDLFAYDSQLAADVFSRIPKIATAIKASNPDI
KAMNVINNNGELAYQSVFHSHFHLIPRYTKDDGFSMTFTDNTDKYSSEELQKIQKKITDRLGD
>Mature_143_residues
MDENCVFCKIITGDIPSYTVYEDDVVKAFLDISQVTPGHTLVVPKKHVPDLFAYDSQLAADVFSRIPKIATAIKASNPDI
KAMNVINNNGELAYQSVFHSHFHLIPRYTKDDGFSMTFTDNTDKYSSEELQKIQKKITDRLGD

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320078, Length=141, Percent_Identity=33.3333333333333, Blast_Score=89, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: NA

Molecular weight: Translated: 16118; Mature: 16118

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS00892 HIT_1 ; PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDENCVFCKIITGDIPSYTVYEDDVVKAFLDISQVTPGHTLVVPKKHVPDLFAYDSQLAA
CCCCCEEEEEEECCCCCCEEEHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHH
DVFSRIPKIATAIKASNPDIKAMNVINNNGELAYQSVFHSHFHLIPRYTKDDGFSMTFTD
HHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCEECCCCCEEEECC
NTDKYSSEELQKIQKKITDRLGD
CCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDENCVFCKIITGDIPSYTVYEDDVVKAFLDISQVTPGHTLVVPKKHVPDLFAYDSQLAA
CCCCCEEEEEEECCCCCCEEEHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHH
DVFSRIPKIATAIKASNPDIKAMNVINNNGELAYQSVFHSHFHLIPRYTKDDGFSMTFTD
HHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCEECCCCCEEEECC
NTDKYSSEELQKIQKKITDRLGD
CCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]