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The map label for this gene is gap [H]

Identifier: 116492261

GI number: 116492261

Start: 512197

End: 513219

Strand: Direct

Name: gap [H]

Synonym: PEPE_0459

Alternate gene names: 116492261

Gene position: 512197-513219 (Clockwise)

Preceding gene: 116492260

Following gene: 116492262

Centisome position: 27.95

GC content: 41.25

Gene sequence:

>1023_bases
ATGACTGTAAAGATTGGTATTAATGGTTTTGGCCGTATTGGTCGTTTAGCATTCCGTCGTATCCACGAATTGGGTGCAAA
ATCAAATGACATCGAAGTTGTTGCTATCAACGATTTGACAAGTCCTGCTTTATTAGCACACTTGCTTAAATATGATTCAA
CACATGGAACTTTTGCTGGTGAAGTTAGTGCAACTGATAACTCAATTATCGTTGACGGCAAAGAATACCGTGTATACGCT
GAACCAAAGGCTCAAGATATTCCTTGGGTTAAGGAAGACGGTGTTGACTTCGTACTTGAATGTACAGGTTTCTACACATC
AAAAGAAAAATCACAAGCTCATTTAGATGCTGGTGCAAAACGTGTATTGGTTTCAGCACCTGCTGGCTCAGATCTTAAGA
CTGTTGTTTACAACGTAAACGATGATGTTTTAACTGCTGACGACCGTATCGTTTCAGCTGGTTCATGTACAACTAACTGT
CTTGCACCAATGGCTTACTTCTTAAACGAAGAATTCGGCGTACAAATTGGTACAATGACAACAGTTCATGCTTACACAAG
TACACAAATGCTTCTTGACGGACCTGTTCGTGGTGGAAACTTCCGTGCTGCACGCGCTGCTGCTGCAAACACAATTCCTC
ACTCAACTGGTGCTGCTAAGGCTATCGGTCTTGTTATCCCAGAATTGAACGGTAAGTTACAAGGACATGCACAACGTGTT
AGCGTTGTTGACGGTTCATTGACAGAACTTGTTTCAATCCTTGACAAGGACGTTACAGTTGAAGAAGTTAATGCTGCTAT
TAAGAAGCATACAGAAGGTAACGAATCATTCGGTTGGAACGAAGACGAAGTTGTATCAAGTGACATCATTGGCACAACAT
ACGGCTCAATCTTTGACCCAACACAAACAGAAGTTACTAAAGCTGGCGACAAGCAATTAGTTAAGACTGTTGCTTGGTAC
GACAACGAATACGGCTTCACTTGCCAAATGGTACGTACTTTATTGAAATTTGCTACTCTTTAA

Upstream 100 bases:

>100_bases
GAAGGTGCAGCAAACGCGATTTTAAAAAAGTAAAGCCATTGTGACTTAACTTTTTAAAATAAATTATTTTTTTAGATTCC
TAAAGGAGGAAATCTTACTT

Downstream 100 bases:

>100_bases
GATTAATTCTTAAAAATTGTAGATTTCAAACCGTCTAATCGGTCTAGGGACGGAGGGAGGTCACTTCCTCCGTCCCTTTT
TTTAGAAAAAATAATTTATT

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MTVKIGINGFGRIGRLAFRRIHELGAKSNDIEVVAINDLTSPALLAHLLKYDSTHGTFAGEVSATDNSIIVDGKEYRVYA
EPKAQDIPWVKEDGVDFVLECTGFYTSKEKSQAHLDAGAKRVLVSAPAGSDLKTVVYNVNDDVLTADDRIVSAGSCTTNC
LAPMAYFLNEEFGVQIGTMTTVHAYTSTQMLLDGPVRGGNFRAARAAAANTIPHSTGAAKAIGLVIPELNGKLQGHAQRV
SVVDGSLTELVSILDKDVTVEEVNAAIKKHTEGNESFGWNEDEVVSSDIIGTTYGSIFDPTQTEVTKAGDKQLVKTVAWY
DNEYGFTCQMVRTLLKFATL

Sequences:

>Translated_340_residues
MTVKIGINGFGRIGRLAFRRIHELGAKSNDIEVVAINDLTSPALLAHLLKYDSTHGTFAGEVSATDNSIIVDGKEYRVYA
EPKAQDIPWVKEDGVDFVLECTGFYTSKEKSQAHLDAGAKRVLVSAPAGSDLKTVVYNVNDDVLTADDRIVSAGSCTTNC
LAPMAYFLNEEFGVQIGTMTTVHAYTSTQMLLDGPVRGGNFRAARAAAANTIPHSTGAAKAIGLVIPELNGKLQGHAQRV
SVVDGSLTELVSILDKDVTVEEVNAAIKKHTEGNESFGWNEDEVVSSDIIGTTYGSIFDPTQTEVTKAGDKQLVKTVAWY
DNEYGFTCQMVRTLLKFATL
>Mature_339_residues
TVKIGINGFGRIGRLAFRRIHELGAKSNDIEVVAINDLTSPALLAHLLKYDSTHGTFAGEVSATDNSIIVDGKEYRVYAE
PKAQDIPWVKEDGVDFVLECTGFYTSKEKSQAHLDAGAKRVLVSAPAGSDLKTVVYNVNDDVLTADDRIVSAGSCTTNCL
APMAYFLNEEFGVQIGTMTTVHAYTSTQMLLDGPVRGGNFRAARAAAANTIPHSTGAAKAIGLVIPELNGKLQGHAQRVS
VVDGSLTELVSILDKDVTVEEVNAAIKKHTEGNESFGWNEDEVVSSDIIGTTYGSIFDPTQTEVTKAGDKQLVKTVAWYD
NEYGFTCQMVRTLLKFATL

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7657116, Length=340, Percent_Identity=43.8235294117647, Blast_Score=256, Evalue=3e-68,
Organism=Homo sapiens, GI7669492, Length=340, Percent_Identity=41.1764705882353, Blast_Score=250, Evalue=1e-66,
Organism=Escherichia coli, GI1788079, Length=336, Percent_Identity=46.4285714285714, Blast_Score=279, Evalue=2e-76,
Organism=Escherichia coli, GI1789295, Length=343, Percent_Identity=41.6909620991254, Blast_Score=250, Evalue=8e-68,
Organism=Caenorhabditis elegans, GI17534679, Length=346, Percent_Identity=43.6416184971098, Blast_Score=250, Evalue=8e-67,
Organism=Caenorhabditis elegans, GI17568413, Length=344, Percent_Identity=43.0232558139535, Blast_Score=249, Evalue=1e-66,
Organism=Caenorhabditis elegans, GI32566163, Length=344, Percent_Identity=43.0232558139535, Blast_Score=249, Evalue=1e-66,
Organism=Caenorhabditis elegans, GI17534677, Length=346, Percent_Identity=43.6416184971098, Blast_Score=249, Evalue=2e-66,
Organism=Saccharomyces cerevisiae, GI6321631, Length=335, Percent_Identity=45.3731343283582, Blast_Score=279, Evalue=5e-76,
Organism=Saccharomyces cerevisiae, GI6322409, Length=335, Percent_Identity=45.3731343283582, Blast_Score=276, Evalue=5e-75,
Organism=Saccharomyces cerevisiae, GI6322468, Length=335, Percent_Identity=44.7761194029851, Blast_Score=275, Evalue=9e-75,
Organism=Drosophila melanogaster, GI19922412, Length=334, Percent_Identity=41.9161676646707, Blast_Score=256, Evalue=2e-68,
Organism=Drosophila melanogaster, GI85725000, Length=340, Percent_Identity=42.6470588235294, Blast_Score=254, Evalue=8e-68,
Organism=Drosophila melanogaster, GI22023983, Length=340, Percent_Identity=42.6470588235294, Blast_Score=254, Evalue=8e-68,
Organism=Drosophila melanogaster, GI17933600, Length=340, Percent_Identity=42.3529411764706, Blast_Score=252, Evalue=2e-67,
Organism=Drosophila melanogaster, GI18110149, Length=340, Percent_Identity=42.3529411764706, Blast_Score=252, Evalue=2e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36628; Mature: 36496

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVKIGINGFGRIGRLAFRRIHELGAKSNDIEVVAINDLTSPALLAHLLKYDSTHGTFAG
CEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCEEE
EVSATDNSIIVDGKEYRVYAEPKAQDIPWVKEDGVDFVLECTGFYTSKEKSQAHLDAGAK
EEECCCCEEEEECCEEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHCCCCC
RVLVSAPAGSDLKTVVYNVNDDVLTADDRIVSAGSCTTNCLAPMAYFLNEEFGVQIGTMT
EEEEECCCCCCCEEEEEECCCCEEECCCCEEECCCCCHHHHHHHHHHHCHHHCEEECCEE
TVHAYTSTQMLLDGPVRGGNFRAARAAAANTIPHSTGAAKAIGLVIPELNGKLQGHAQRV
EEEEECCCEEEEECCCCCCCCCHHHHHHHCCCCCCCCCHHEEEEEEECCCCCCCCCEEEE
SVVDGSLTELVSILDKDVTVEEVNAAIKKHTEGNESFGWNEDEVVSSDIIGTTYGSIFDP
EEECCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCC
TQTEVTKAGDKQLVKTVAWYDNEYGFTCQMVRTLLKFATL
CHHHHHHCCHHHHHHHHHHCCCCCCEEHHHHHHHHHHHCC
>Mature Secondary Structure 
TVKIGINGFGRIGRLAFRRIHELGAKSNDIEVVAINDLTSPALLAHLLKYDSTHGTFAG
EEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCEEE
EVSATDNSIIVDGKEYRVYAEPKAQDIPWVKEDGVDFVLECTGFYTSKEKSQAHLDAGAK
EEECCCCEEEEECCEEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHCCCCC
RVLVSAPAGSDLKTVVYNVNDDVLTADDRIVSAGSCTTNCLAPMAYFLNEEFGVQIGTMT
EEEEECCCCCCCEEEEEECCCCEEECCCCEEECCCCCHHHHHHHHHHHCHHHCEEECCEE
TVHAYTSTQMLLDGPVRGGNFRAARAAAANTIPHSTGAAKAIGLVIPELNGKLQGHAQRV
EEEEECCCEEEEECCCCCCCCCHHHHHHHCCCCCCCCCHHEEEEEEECCCCCCCCCEEEE
SVVDGSLTELVSILDKDVTVEEVNAAIKKHTEGNESFGWNEDEVVSSDIIGTTYGSIFDP
EEECCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCC
TQTEVTKAGDKQLVKTVAWYDNEYGFTCQMVRTLLKFATL
CHHHHHHCCHHHHHHHHHHCCCCCCEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579064 [H]