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The map label for this gene is lgt

Identifier: 116492245

GI number: 116492245

Start: 490979

End: 491815

Strand: Direct

Name: lgt

Synonym: PEPE_0442

Alternate gene names: 116492245

Gene position: 490979-491815 (Clockwise)

Preceding gene: 116492244

Following gene: 116492246

Centisome position: 26.79

GC content: 40.62

Gene sequence:

>837_bases
GTGAATTTAACGTTAGGAGCACTAAATCCAATTGCCTTTAATCTTGGTGGAATTCAAGTTCATTGGTATGGAATTATCAT
TGCGTCAGCAGTGGTGTTAGCGACGATTTTGGCAGTTCAAGAAGCTAAAAGGCGAAGAATCGATCCAGATTCTATCTACG
ATTTGATTTTATGGGCCTTACCAGTGGCGATTATTACCGCTCGAATGTATTACGTTATTTTTGAGTGGGGATATTACCAA
AACCATGTCGATGAAATTGTACGCGTTTGGGACGGTGGTATTGCCATTTATGGGGCCTTGATTGGGGCTGGAATCGTGGT
CTACCTCTTCTGTCGTGCAAATTGGATTCCAGTTTGGTTAATGTTGGATATCATCGCTCCAGTATTGATTATGGCCCAAG
GTATTGGTCGATGGGGTAATTTTATGAATCAAGAGGCTTTCGGCAGAATTACTAGCTTAACATTTCTCCAAAGTCTTCAT
TTGCCCCATTTTATTATTCAACAAATGCTGATTGATGGAGCCTACCGTCAACCAACTTTTTTATATGAATCGCTTTGGGA
CATCTTGGGCTTTATTGTATTGATGAGTTTGAGACATAAAAAACATTTATTCAAACAAGGGGAAGTGTTCTTGTCCTATG
TAATTTGGTACGCGTTTGGTCGCTTTTTTGTCGAAGGGATGCGCACTGATAGTTTGATGCTATTAGGCATCCGCGTGTCA
CAATGGCTTTCGGTAATACTTTTTATCGGAGCAATTGGTATATTGGTGTTCCGCCGTAAATCGATGCGAGAACGCCTACC
AGATTATTTGGAAGGTAATCAGCTTTCACCAAAATGA

Upstream 100 bases:

>100_bases
ACTTTAGAGCTAAAAATATGGGATATGATGCAACCAAAGTTTTTGATCGTAACTTAAATGAGTTGATCAAAGATAATTCC
CAGAAATAGGAGTGGATTTT

Downstream 100 bases:

>100_bases
ACTTGAGTAAAGTACCTTTGTATACGATAATAGAAAGGTACATAAATTATTTTTAAATTTAAGATTGTAAGGGGATTAAC
TATGGTAAAAAAAGTTGCAG

Product: prolipoprotein diacylglyceryl transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MNLTLGALNPIAFNLGGIQVHWYGIIIASAVVLATILAVQEAKRRRIDPDSIYDLILWALPVAIITARMYYVIFEWGYYQ
NHVDEIVRVWDGGIAIYGALIGAGIVVYLFCRANWIPVWLMLDIIAPVLIMAQGIGRWGNFMNQEAFGRITSLTFLQSLH
LPHFIIQQMLIDGAYRQPTFLYESLWDILGFIVLMSLRHKKHLFKQGEVFLSYVIWYAFGRFFVEGMRTDSLMLLGIRVS
QWLSVILFIGAIGILVFRRKSMRERLPDYLEGNQLSPK

Sequences:

>Translated_278_residues
MNLTLGALNPIAFNLGGIQVHWYGIIIASAVVLATILAVQEAKRRRIDPDSIYDLILWALPVAIITARMYYVIFEWGYYQ
NHVDEIVRVWDGGIAIYGALIGAGIVVYLFCRANWIPVWLMLDIIAPVLIMAQGIGRWGNFMNQEAFGRITSLTFLQSLH
LPHFIIQQMLIDGAYRQPTFLYESLWDILGFIVLMSLRHKKHLFKQGEVFLSYVIWYAFGRFFVEGMRTDSLMLLGIRVS
QWLSVILFIGAIGILVFRRKSMRERLPDYLEGNQLSPK
>Mature_278_residues
MNLTLGALNPIAFNLGGIQVHWYGIIIASAVVLATILAVQEAKRRRIDPDSIYDLILWALPVAIITARMYYVIFEWGYYQ
NHVDEIVRVWDGGIAIYGALIGAGIVVYLFCRANWIPVWLMLDIIAPVLIMAQGIGRWGNFMNQEAFGRITSLTFLQSLH
LPHFIIQQMLIDGAYRQPTFLYESLWDILGFIVLMSLRHKKHLFKQGEVFLSYVIWYAFGRFFVEGMRTDSLMLLGIRVS
QWLSVILFIGAIGILVFRRKSMRERLPDYLEGNQLSPK

Specific function: Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins

COG id: COG0682

COG function: function code M; Prolipoprotein diacylglyceryltransferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lgt family

Homologues:

Organism=Escherichia coli, GI1789192, Length=287, Percent_Identity=26.4808362369338, Blast_Score=83, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LGT_PEDPA (Q03GY4)

Other databases:

- EMBL:   CP000422
- RefSeq:   YP_803980.1
- STRING:   Q03GY4
- GeneID:   4418373
- GenomeReviews:   CP000422_GR
- KEGG:   ppe:PEPE_0442
- NMPDR:   fig|278197.10.peg.410
- eggNOG:   COG0682
- HOGENOM:   HBG450278
- OMA:   TSHIRVA
- ProtClustDB:   PRK00052
- BioCyc:   PPEN278197:PEPE_0442-MONOMER
- HAMAP:   MF_01147
- InterPro:   IPR001640
- TIGRFAMs:   TIGR00544

Pfam domain/function: PF01790 LGT

EC number: 2.4.99.- [C]

Molecular weight: Translated: 31933; Mature: 31933

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: PS01311 LGT

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x133b4d1c)-; HASH(0x162ccf20)-; HASH(0x16baf988)-; HASH(0x413f9f0c)-; HASH(0x1612a3dc)-; HASH(0x16946830)-; HASH(0x1697e600)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCH
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA