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The map label for this gene is dppE [H]

Identifier: 116492199

GI number: 116492199

Start: 440927

End: 442549

Strand: Direct

Name: dppE [H]

Synonym: PEPE_0396

Alternate gene names: 116492199

Gene position: 440927-442549 (Clockwise)

Preceding gene: 116492195

Following gene: 116492200

Centisome position: 24.06

GC content: 37.58

Gene sequence:

>1623_bases
ATGAAACTAAAAACAGTTGTAAAGCTCGGCTCAGTTGCATTAGCTTCAACGTTTGTTTTGGCAGCATGTGGTTCGAGCAA
TTCAAATAGTAAAAAAACAGCAAACATTCAAGAGTCTGCTGAATTAGCAACAATGGATCAATCTAAGGTTACAGATGTGG
TTGGTTTTACCCAATTAGGTAGTACAGAAGAAGGACTATATCGAATTGGTAAGAACAATAAAGTTGAAAATGCGATTGCT
ACAAAAACTAAAGTTTCAGATGATCACAAAACTTACACATTTACTCTACGAAAAGGGGTTAAGTGGAGTAATGGCGATGA
GGTAACTGCAAAAGACTTCGTATATGGTTGGCAAAGAACGGTAAATCCGAAAACAGCTTCCCAATACGCATATATCTTCT
CGGGTGTTAAAAATGCCGATAAAATTGCTAGTGGTAAAGCGAACTATAAATCATTGGGAATTAAGGCTGATGGCAAGTAT
AAGTTGACGGTGACCCTTGATCGTCCGATTTCTTACTTTAAACTCCTGATGGGAATGCCAACCTTCTTCCCTCAAAATGA
GAAGGCCGTTAAAAAGTACGGTGATAAGTATGGTACTTCGGCTAAAACAACAGTTTATAACGGTCCATATCGAATGGAAG
GTTGGACAGGTTCTAACTTAAGCTGGAAGCTCGTTAAGAACAAGACTTACTGGGATAAGAAAAATGTCAAGATGGATACT
TTGAACTGGAAAGTGGTTAAAGACACTGGAACGGCTCTGAACATGTATAATAGTAATAAGCTTGATCAAATGACCTTATC
TAGTGAACAGGTTAAACAATACAAGAATAATAAAGACTACGTTAAGTACTTAAATGCTTCAACTTTCTACATTGAATATA
ACCAAAAGAAGGACAAGTACTTTAAGAATGCTAAAATCCGTAAGGCTCTTTCGTTAGCTATTAATCGTCAACAATTTGTT
GATAAGATTAAAGGTGATGGATCAACGGTTGCAACGGGAGTAACGCCGGCTAAGTTGGCTAAGGATGAAAAGAATGGCAA
GGACTTTGCTTCTGAAGTCGATGTTAAATCAGCTTCGGAATACAATTTGAAAGAAGCTAAAAAGTTGATGGCTGAAGGTC
TTAAAGAAGAAGGTATGCGTTCATTGAACTTCCAACTTCTTAGTGATGATACTACCGCTGCTAAGCAGTCAACTGAATTC
TTACAATCAGCATTTGAAAAGATACCTAATGTGAAAGTTTCGTTAAGTAACGTGCCATTTAAGAACCGTTTAGCAAACTC
GGTCGATGGTAAATTCGATGCAGTTATTACAGCATGGAGCGCTGATTTCTCAGATCCAATCTCATTCCTTCAACTATTTA
CGTCTGATAACTCACAAAATAACGGTAAATGGGCTAATAAGGAATACGATAAGTTGATTGAGGCTGCGAATACTACTGAC
GCTGGTAATACTGAAAAACGTTGGGATGATATGTTGAAGGCGGAACAAATCCTATTGAAGGATCAAGCAGTTGCTCCACT
TTATCAACAAGGACAATCAATGTTGCGTAAAACCAACCTTAAGGGTATTGTGTATAACTCGGCTGGATTGAACTTTGATT
ACAAGCAGGCATATATCAAATAA

Upstream 100 bases:

>100_bases
TTAAAATAATTAGAGTTTAATATTGATTTTAATATAATTTTAATATATACTCATTTTCATAGTAAAAGATAATTGGTTGA
AAATATAGGGAGTGTGTGAG

Downstream 100 bases:

>100_bases
TTAAAAATGGGAACAAATTACATTGGGTGAGAGTGATACATTGCTCTTACCCTTTGTGCATATTGGACCAGAGATTGTGA
GGGAGATTTATGGCAAGATA

Product: ABC-type oligopeptide transport system, periplasmic component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 540; Mature: 540

Protein sequence:

>540_residues
MKLKTVVKLGSVALASTFVLAACGSSNSNSKKTANIQESAELATMDQSKVTDVVGFTQLGSTEEGLYRIGKNNKVENAIA
TKTKVSDDHKTYTFTLRKGVKWSNGDEVTAKDFVYGWQRTVNPKTASQYAYIFSGVKNADKIASGKANYKSLGIKADGKY
KLTVTLDRPISYFKLLMGMPTFFPQNEKAVKKYGDKYGTSAKTTVYNGPYRMEGWTGSNLSWKLVKNKTYWDKKNVKMDT
LNWKVVKDTGTALNMYNSNKLDQMTLSSEQVKQYKNNKDYVKYLNASTFYIEYNQKKDKYFKNAKIRKALSLAINRQQFV
DKIKGDGSTVATGVTPAKLAKDEKNGKDFASEVDVKSASEYNLKEAKKLMAEGLKEEGMRSLNFQLLSDDTTAAKQSTEF
LQSAFEKIPNVKVSLSNVPFKNRLANSVDGKFDAVITAWSADFSDPISFLQLFTSDNSQNNGKWANKEYDKLIEAANTTD
AGNTEKRWDDMLKAEQILLKDQAVAPLYQQGQSMLRKTNLKGIVYNSAGLNFDYKQAYIK

Sequences:

>Translated_540_residues
MKLKTVVKLGSVALASTFVLAACGSSNSNSKKTANIQESAELATMDQSKVTDVVGFTQLGSTEEGLYRIGKNNKVENAIA
TKTKVSDDHKTYTFTLRKGVKWSNGDEVTAKDFVYGWQRTVNPKTASQYAYIFSGVKNADKIASGKANYKSLGIKADGKY
KLTVTLDRPISYFKLLMGMPTFFPQNEKAVKKYGDKYGTSAKTTVYNGPYRMEGWTGSNLSWKLVKNKTYWDKKNVKMDT
LNWKVVKDTGTALNMYNSNKLDQMTLSSEQVKQYKNNKDYVKYLNASTFYIEYNQKKDKYFKNAKIRKALSLAINRQQFV
DKIKGDGSTVATGVTPAKLAKDEKNGKDFASEVDVKSASEYNLKEAKKLMAEGLKEEGMRSLNFQLLSDDTTAAKQSTEF
LQSAFEKIPNVKVSLSNVPFKNRLANSVDGKFDAVITAWSADFSDPISFLQLFTSDNSQNNGKWANKEYDKLIEAANTTD
AGNTEKRWDDMLKAEQILLKDQAVAPLYQQGQSMLRKTNLKGIVYNSAGLNFDYKQAYIK
>Mature_540_residues
MKLKTVVKLGSVALASTFVLAACGSSNSNSKKTANIQESAELATMDQSKVTDVVGFTQLGSTEEGLYRIGKNNKVENAIA
TKTKVSDDHKTYTFTLRKGVKWSNGDEVTAKDFVYGWQRTVNPKTASQYAYIFSGVKNADKIASGKANYKSLGIKADGKY
KLTVTLDRPISYFKLLMGMPTFFPQNEKAVKKYGDKYGTSAKTTVYNGPYRMEGWTGSNLSWKLVKNKTYWDKKNVKMDT
LNWKVVKDTGTALNMYNSNKLDQMTLSSEQVKQYKNNKDYVKYLNASTFYIEYNQKKDKYFKNAKIRKALSLAINRQQFV
DKIKGDGSTVATGVTPAKLAKDEKNGKDFASEVDVKSASEYNLKEAKKLMAEGLKEEGMRSLNFQLLSDDTTAAKQSTEF
LQSAFEKIPNVKVSLSNVPFKNRLANSVDGKFDAVITAWSADFSDPISFLQLFTSDNSQNNGKWANKEYDKLIEAANTTD
AGNTEKRWDDMLKAEQILLKDQAVAPLYQQGQSMLRKTNLKGIVYNSAGLNFDYKQAYIK

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789397, Length=514, Percent_Identity=29.5719844357977, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1787495, Length=449, Percent_Identity=32.739420935412, Blast_Score=196, Evalue=4e-51,
Organism=Escherichia coli, GI87081878, Length=494, Percent_Identity=29.3522267206478, Blast_Score=179, Evalue=5e-46,
Organism=Escherichia coli, GI1787052, Length=547, Percent_Identity=23.7659963436929, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1789966, Length=470, Percent_Identity=25.3191489361702, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1787762, Length=540, Percent_Identity=24.8148148148148, Blast_Score=88, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 60452; Mature: 60452

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKTVVKLGSVALASTFVLAACGSSNSNSKKTANIQESAELATMDQSKVTDVVGFTQLG
CCCHHHHHHHHHHHHHHHHHEECCCCCCCCCEECCHHHHHHHHHCCHHHHHHHHHHHHCC
STEEGLYRIGKNNKVENAIATKTKVSDDHKTYTFTLRKGVKWSNGDEVTAKDFVYGWQRT
CCHHHHEECCCCCCCCHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHC
VNPKTASQYAYIFSGVKNADKIASGKANYKSLGIKADGKYKLTVTLDRPISYFKLLMGMP
CCCCHHHHHHHHHHCCCCHHHHHCCCCCHHEECEECCCEEEEEEEECCCHHHHHHHHCCC
TFFPQNEKAVKKYGDKYGTSAKTTVYNGPYRMEGWTGSNLSWKLVKNKTYWDKKNVKMDT
CCCCCCHHHHHHHHHHHCCCCCEEEECCCEEECCCCCCCCEEEEEECCCCCCCCCCEEEC
LNWKVVKDTGTALNMYNSNKLDQMTLSSEQVKQYKNNKDYVKYLNASTFYIEYNQKKDKY
CEEEEEECCCCEEEECCCCCCHHHHCCHHHHHHHHCCCCCEEEECCEEEEEEECCCHHHH
FKNAKIRKALSLAINRQQFVDKIKGDGSTVATGVTPAKLAKDEKNGKDFASEVDVKSASE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHCCCCCCCHHHHHCCCCCCCC
YNLKEAKKLMAEGLKEEGMRSLNFQLLSDDTTAAKQSTEFLQSAFEKIPNVKVSLSNVPF
CCHHHHHHHHHHHHHHCCHHHCCEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCH
KNRLANSVDGKFDAVITAWSADFSDPISFLQLFTSDNSQNNGKWANKEYDKLIEAANTTD
HHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCC
AGNTEKRWDDMLKAEQILLKDQAVAPLYQQGQSMLRKTNLKGIVYNSAGLNFDYKQAYIK
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHCC
>Mature Secondary Structure
MKLKTVVKLGSVALASTFVLAACGSSNSNSKKTANIQESAELATMDQSKVTDVVGFTQLG
CCCHHHHHHHHHHHHHHHHHEECCCCCCCCCEECCHHHHHHHHHCCHHHHHHHHHHHHCC
STEEGLYRIGKNNKVENAIATKTKVSDDHKTYTFTLRKGVKWSNGDEVTAKDFVYGWQRT
CCHHHHEECCCCCCCCHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHC
VNPKTASQYAYIFSGVKNADKIASGKANYKSLGIKADGKYKLTVTLDRPISYFKLLMGMP
CCCCHHHHHHHHHHCCCCHHHHHCCCCCHHEECEECCCEEEEEEEECCCHHHHHHHHCCC
TFFPQNEKAVKKYGDKYGTSAKTTVYNGPYRMEGWTGSNLSWKLVKNKTYWDKKNVKMDT
CCCCCCHHHHHHHHHHHCCCCCEEEECCCEEECCCCCCCCEEEEEECCCCCCCCCCEEEC
LNWKVVKDTGTALNMYNSNKLDQMTLSSEQVKQYKNNKDYVKYLNASTFYIEYNQKKDKY
CEEEEEECCCCEEEECCCCCCHHHHCCHHHHHHHHCCCCCEEEECCEEEEEEECCCHHHH
FKNAKIRKALSLAINRQQFVDKIKGDGSTVATGVTPAKLAKDEKNGKDFASEVDVKSASE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHCCCCCCCHHHHHCCCCCCCC
YNLKEAKKLMAEGLKEEGMRSLNFQLLSDDTTAAKQSTEFLQSAFEKIPNVKVSLSNVPF
CCHHHHHHHHHHHHHHCCHHHCCEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCH
KNRLANSVDGKFDAVITAWSADFSDPISFLQLFTSDNSQNNGKWANKEYDKLIEAANTTD
HHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCC
AGNTEKRWDDMLKAEQILLKDQAVAPLYQQGQSMLRKTNLKGIVYNSAGLNFDYKQAYIK
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]